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Volumn 877, Issue 27, 2009, Pages 3137-3143
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Simultaneous quantification of psoralen and isopsoralen in rat plasma by ultra-performance liquid chromatography/tandem mass spectrometry and its application to a pharmacokinetic study after oral administration of Haigou Pill
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Author keywords
Isomers; Isopsoralen; Pharmacokinetics; Psoralen; UPLC MS MS
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Indexed keywords
ACQUITY;
CALIBRATION CURVES;
CHROMATOGRAPHIC SEPARATIONS;
CONCENTRATION RANGES;
EXTRACTION RECOVERY;
FURAZOLIDONE;
INTERNAL STANDARDS;
ISOPSORALEN;
LINEAR GRADIENTS;
LIQUID CHROMATOGRAPHY/TANDEM MASS SPECTROMETRY;
LOWER LIMIT OF QUANTITATIONS;
MATRIX EFFECTS;
ORAL ADMINISTRATION;
PHARMACOKINETIC STUDIES;
PLASMA SAMPLES;
POSITIVE ION MODE;
PRE-TREATMENT;
PROTEIN PRECIPITATION;
PSORALEN;
RAT PLASMA;
RUNTIMES;
UPLC/MS/MS;
VALIDATED METHODS;
ACETONITRILE;
HIGH PRESSURE LIQUID CHROMATOGRAPHY;
LIQUIDS;
MASS SPECTROMETERS;
MASS SPECTROMETRY;
ORGANIC ACIDS;
PHARMACOKINETICS;
PLASMA (HUMAN);
PLASMAS;
ISOMERS;
ACETONITRILE;
ANGELICIN;
FORMIC ACID;
FURAZOLIDONE;
PSORALEN;
WATER;
ANALYTICAL EQUIPMENT;
ANIMAL EXPERIMENT;
AREA UNDER THE CURVE;
ARTICLE;
CONCENTRATION (PARAMETERS);
CONTROLLED STUDY;
DRUG BLOOD LEVEL;
DRUG STABILITY;
DRUG STORAGE;
FLOW RATE;
HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;
IONIZATION;
ISOMER;
MALE;
MAXIMUM PLASMA CONCENTRATION;
NONHUMAN;
PRECIPITATION;
PRIORITY JOURNAL;
RAT;
TANDEM MASS SPECTROMETRY;
TEMPERATURE;
TIME TO MAXIMUM PLASMA CONCENTRATION;
ADMINISTRATION, ORAL;
ANIMALS;
CHROMATOGRAPHY, HIGH PRESSURE LIQUID;
DRUGS, CHINESE HERBAL;
FABACEAE;
FICUSIN;
LINEAR MODELS;
MALE;
PSORALENS;
RATS;
RATS, WISTAR;
REPRODUCIBILITY OF RESULTS;
SENSITIVITY AND SPECIFICITY;
TANDEM MASS SPECTROMETRY;
RATTUS;
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EID: 69749088528
PISSN: 15700232
EISSN: None
Source Type: Journal
DOI: 10.1016/j.jchromb.2009.07.035 Document Type: Article |
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Times cited : (19)
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References (23)
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