A rapid and sensitive LC-MS/MS method for quantification of four anthocyanins and its application in a clinical pharmacology study of a bioadhesive black raspberry gel

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 877, Issue 31, 2009, Pages 4027-4034

  Ling, Yonghua ^a   Ren, Chen ^a   Mallery, Susan R ^a   Ugalde, Carlos M ^a   Pei, Ping ^a   Saradhi, U V R Vijaya ^a   Stoner, Gary D ^b,c   Chan, Kenneth K ^a,b,c   Liu, Zhongfa ^a,b  

^a OHIO STATE UNIVERSITY   (United States)

^b OHIO STATE UNIVERSITY   (United States)

^c THE OHIO STATE UNIVERSITY COLLEGE OF MEDICINE   (United States)

Author keywords

Anthocyanins; Bioadhesive black raspberry gel; LC MS MS; Pharmacology; Quantitation

Indexed keywords

ANTHOCYANINS; BIOADHESIVES; CHEMOPREVENTIVE EFFECTS; CLINICAL PHARMACOLOGY; COEFFICIENTS OF VARIATIONS; CYANIDIN; HIGHLY SENSITIVE; HUMAN PLASMAS; HUMAN SALIVA; LC-MS/MS; LOWER LIMIT OF QUANTIFICATIONS; ORAL MUCOSA; ORAL TISSUES; TISSUE HOMOGENATES; TISSUE LEVELS; TOPICAL APPLICATION;

BODY FLUIDS; QUALITY CONTROL; QUALITY FUNCTION DEPLOYMENT; TOTAL QUALITY MANAGEMENT;

GELS;

ADHESIVE AGENT; ANTHOCYANIN; BIOADHESIVE; CYANIDIN 3 (2G XYLOSYL)RUTINOSIDE; CYANIDIN 3 GLUCOSIDE; CYANIDIN 3 RUTINOSIDE; CYANIDIN 3 SAMBUBIOSIDE; UNCLASSIFIED DRUG;

ACCURACY; ARTICLE; DRUG BLOOD LEVEL; DRUG DISTRIBUTION; DRUG SALIVA LEVEL; DRUG STABILITY; FREEZE DRYING; GEL; HUMAN; HUMAN TISSUE; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RASPBERRY; VALIDATION PROCESS;

ANTHOCYANINS; CHROMATOGRAPHY, LIQUID; GELS; GLUCOSIDES; HUMANS; MOUTH MUCOSA; PLANT EXTRACTS; REFERENCE STANDARDS; SALIVA; TANDEM MASS SPECTROMETRY;

RUBUS OCCIDENTALIS;

EID: 72049129970     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2009.10.026     Document Type: Article

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