Peptides Composed of Alternating L- and D-Amino Acids Inhibit Amyloidogenesis in Three Distinct Amyloid Systems Independent of Sequence

Journal of Molecular Biology

Volumn 428, Issue 11, 2016, Pages 2317-2328

  Kellock, Jackson ^a   Hopping, Gene ^a   Caughey, Byron ^b   Daggett, Valerie ^a  

^a University of Washington   (United States)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

amyloid; beta amyloid; inhibitor; toxic oligomer; sheet

Indexed keywords

AMINO ACID; AMINO ACID DERIVATIVE; AMYLOID PROTEIN; DEXTRO AMINO ACID; AMYLIN; AMYLOID; AMYLOID BETA PROTEIN; PREALBUMIN; PROTEIN AGGREGATE;

AMYLOIDOGENESIS; AMYLOIDOSIS; ARTICLE; CHIRALITY; CIRCULAR DICHROISM; HUMAN; MOLECULAR DYNAMICS; MOLECULAR PATHOLOGY; PEPTIDE ANALYSIS; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN IMMOBILIZATION; PROTEIN SECONDARY STRUCTURE; PROTEIN STABILITY; AMINO ACID SEQUENCE; METABOLISM; PHYSIOLOGY; PROTEIN MULTIMERIZATION;

AMINO ACID SEQUENCE; AMINO ACIDS; AMYLOID; AMYLOID BETA-PEPTIDES; AMYLOIDOGENIC PROTEINS; AMYLOIDOSIS; HUMANS; ISLET AMYLOID POLYPEPTIDE; MOLECULAR DYNAMICS SIMULATION; PREALBUMIN; PROTEIN AGGREGATES; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, SECONDARY;

EID: 84964614548     PISSN: 00222836     EISSN: 10898638     Source Type: Journal    
DOI: 10.1016/j.jmb.2016.03.013     Document Type: Article

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