Identification of beta-amyloid-binding sites on transthyretin

Protein Engineering, Design and Selection

Volumn 25, Issue 7, 2012, Pages 337-345

  Du, Jiali ^a   Cho, Patricia Y ^a   Yang, Dennis T ^a   Murphy, Regina M ^a  

^a University of Wisconsin Madison   (United States)

Author keywords

beta amyloid; scanning alanine mutagenesis; SPOT peptide arrays; transthyretin

Indexed keywords

BETA-AMYLOID; NATIVE PROTEINS; NEUROTOXICITY; PEPTIDE ARRAYS; STRONG BINDING; TETRAMER STABILITY; TRANSTHYRETIN; WILD TYPES;

AMINO ACIDS; OLIGOMERS; PEPTIDES;

GLYCOPROTEINS;

ALANINE; AMYLOID BETA PROTEIN; PREALBUMIN;

AMINO ACID SEQUENCE; ARTICLE; BETA SHEET; BINDING SITE; CONTROLLED STUDY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN STABILITY; PROTEIN STRUCTURE;

ALANINE; AMINO ACID SEQUENCE; AMYLOID BETA-PEPTIDES; BINDING SITES; HUMANS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; PREALBUMIN; PROTEIN BINDING; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, SECONDARY;

EID: 84862994625     PISSN: 17410126     EISSN: 17410134     Source Type: Journal    
DOI: 10.1093/protein/gzs026     Document Type: Article

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