The acid-mediated denaturation pathway of transthyretin yields a conformational intermediate that can self-assemble into amyloid

Biochemistry

Volumn 35, Issue 20, 1996, Pages 6470-6482

  Lai, Zhihong ^a   Colón, Wilfredo ^a,b   Kelly, Jeffery W ^a  

^a TEXAS A AND M UNIVERSITY   (United States)

^b FOX CHASE CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID; PREALBUMIN;

AMINO ACID SEQUENCE; ARTICLE; PH; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN DENATURATION; PROTEIN QUATERNARY STRUCTURE; PROTEIN TERTIARY STRUCTURE;

AMYLOID; AMYLOIDOSIS; ANIMALS; ESCHERICHIA COLI; HUMANS; HYDROGEN-ION CONCENTRATION; MODELS, MOLECULAR; MOLECULAR STRUCTURE; MUTAGENESIS, SITE-DIRECTED; PREALBUMIN; PROTEIN CONFORMATION; PROTEIN DENATURATION; PROTEIN FOLDING; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS;

EID: 0030004644     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi952501g     Document Type: Article

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