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Volumn 32, Issue 8, 2015, Pages 2130-2140

Gene expression evolves under a house-of-cards model of stabilizing selection

Author keywords

Gene expression; House of Cards; Quantitative genomics; Regulatory evolution; Stabilizing selection

Indexed keywords

BUDDING; DROSOPHILA; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETIC VARIABILITY; MODEL; MUTATION ACCUMULATION; MUTATION RATE; PHENOTYPE; PREDICTION; YEAST; BIOLOGICAL MODEL; MOLECULAR EVOLUTION; PHYSIOLOGY;

EID: 84964592973     PISSN: 07374038     EISSN: 15371719     Source Type: Journal    
DOI: 10.1093/molbev/msv094     Document Type: Article
Times cited : (55)

References (80)
  • 1
    • 79954988547 scopus 로고    scopus 로고
    • Effective population size and the efficacy of selection on the X chromosomes of two closely related Drosophila species
    • Andolfatto P, Wong KM, Bachtrog D. 2011. Effective population size and the efficacy of selection on the X chromosomes of two closely related Drosophila species. Genome Biol EVol. 3:114-128.
    • (2011) Genome Biol EVol. , vol.3 , pp. 114-128
    • Andolfatto, P.1    Wong, K.M.2    Bachtrog, D.3
  • 2
    • 59049088893 scopus 로고    scopus 로고
    • Optimization of gene expression by natural selection
    • Bedford T, Hartl D. 2009. Optimization of gene expression by natural selection. Proc Natl Acad Sci USA. 106:1133-1138.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 1133-1138
    • Bedford, T.1    Hartl, D.2
  • 4
    • 0037177625 scopus 로고    scopus 로고
    • Genetic dissection of transcriptional regulation in budding yeast
    • Brem R, Yvert G, Clinton R, Kruglyak L. 2002. Genetic dissection of transcriptional regulation in budding yeast. Science 296:752-755.
    • (2002) Science , vol.296 , pp. 752-755
    • Brem, R.1    Yvert, G.2    Clinton, R.3    Kruglyak, L.4
  • 5
    • 44849142385 scopus 로고    scopus 로고
    • Cascading transcriptional effects of a naturally occurring frameshift mutation in Saccharomyces cerevisiae
    • Brown K, Landry C, Hartl D, Cavalieri D. 2008. Cascading transcriptional effects of a naturally occurring frameshift mutation in Saccharomyces cerevisiae. Mol Ecol. 17:2985-2997.
    • (2008) Mol Ecol. , vol.17 , pp. 2985-2997
    • Brown, K.1    Landry, C.2    Hartl, D.3    Cavalieri, D.4
  • 6
    • 0024938738 scopus 로고
    • Maintenance of genetic variability by mutation selection balance - A child's guide through the jungle
    • Bulmer MG 1989. Maintenance of genetic variability by mutation selection balance - a child's guide through the jungle. Genome 31: 761-767.
    • (1989) Genome , vol.31 , pp. 761-767
    • Bulmer, M.G.1
  • 8
    • 0024936691 scopus 로고
    • How much heritable variation can be maintained in finite populations by mutation selection balance
    • Burger R, Wagner GP, Stettinger F. 1989. How much heritable variation can be maintained in finite populations by mutation selection balance. Evolution 43:1748-1766.
    • (1989) Evolution , vol.43 , pp. 1748-1766
    • Burger, R.1    Wagner, G.P.2    Stettinger, F.3
  • 9
    • 59449090035 scopus 로고    scopus 로고
    • Evolution of primate gene expression: Drift and corrective sweeps?
    • Chaix R, Somel M, Kreil DP, Khaitovich P, Lunter GA. 2008. Evolution of primate gene expression: drift and corrective sweeps? Genetics 180: 1379-1389.
    • (2008) Genetics , vol.180 , pp. 1379-1389
    • Chaix, R.1    Somel, M.2    Kreil, D.P.3    Khaitovich, P.4    Lunter, G.A.5
  • 10
    • 84872036603 scopus 로고    scopus 로고
    • Genome-wide fine-scale recombination rate variation in Drosophila melanogaster
    • Chan AH, Jenkins PA, Song YS. 2012. Genome-wide fine-scale recombination rate variation in Drosophila melanogaster. PLoS Genet. 8: e1003090.
    • (2012) PLoS Genet , vol.8
    • Chan, A.H.1    Jenkins, P.A.2    Song, Y.S.3
  • 11
    • 60349093708 scopus 로고    scopus 로고
    • Effective population size and patterns of molecular evolution and variation
    • Charlesworth B. 2009. Effective population size and patterns of molecular evolution and variation. Nat Rev Genet. 10:195-205.
    • (2009) Nat Rev Genet , vol.10 , pp. 195-205
    • Charlesworth, B.1
  • 12
    • 63449105244 scopus 로고    scopus 로고
    • Intrinsic variability of gene expression encoded in nucleosome positioning sequences
    • Choi J, Kim Y. 2009. Intrinsic variability of gene expression encoded in nucleosome positioning sequences. Nat Genet. 41:498-503.
    • (2009) Nat Genet , vol.41 , pp. 498-503
    • Choi, J.1    Kim, Y.2
  • 14
    • 33644768092 scopus 로고    scopus 로고
    • Nucleotide polymorphism and linkage disequilibrium in wild populations of the partial selfer Caenorhabditis elegans
    • Cutter AD 2006. Nucleotide polymorphism and linkage disequilibrium in wild populations of the partial selfer Caenorhabditis elegans. Genetics 172:171-184.
    • (2006) Genetics , vol.172 , pp. 171-184
    • Cutter, A.D.1
  • 15
    • 18144405733 scopus 로고    scopus 로고
    • The transcriptional consequences of mutation and natural selection in Caenorhabditis elegans
    • Denver DR, Morris K, Streelman JT, Kim SK, Lynch M, Thomas WK. 2005. The transcriptional consequences of mutation and natural selection in Caenorhabditis elegans. Nat Genet. 37:544-548.
    • (2005) Nat Genet , vol.37 , pp. 544-548
    • Denver, D.R.1    Morris, K.2    Streelman, J.T.3    Kim, S.K.4    Lynch, M.5    Thomas, W.K.6
  • 16
    • 84904565859 scopus 로고    scopus 로고
    • Mapping small effect mutations in Saccharomyces cerevisiae: Impacts of experimental design and mutational properties
    • Duveau F, BP M, Gruber J, Mack K, Sood N, Brooks T, Wittkopp P. 2014. Mapping small effect mutations in Saccharomyces cerevisiae: impacts of experimental design and mutational properties. G3 4: 1205-1216.
    • (2014) G3 , vol.4 , pp. 1205-1216
    • Duveau, F.1    Bp, M.2    Gruber, J.3    Mack, K.4    Sood, N.5    Brooks, T.6    Wittkopp, P.7
  • 18
    • 78649310938 scopus 로고    scopus 로고
    • Shifts in the intensity of purifying selection: An analysis of genomewide polymorphism data from two closely related yeast species
    • Elyashiv E, Bullaughey K, Sattath S, Rinott Y, Przeworski M, Sella G. 2010. Shifts in the intensity of purifying selection: an analysis of genomewide polymorphism data from two closely related yeast species. Genome Res. 20:1558-1573.
    • (2010) Genome Res. , vol.20 , pp. 1558-1573
    • Elyashiv, E.1    Bullaughey, K.2    Sattath, S.3    Rinott, Y.4    Przeworski, M.5    Sella, G.6
  • 19
    • 33846633697 scopus 로고    scopus 로고
    • Resolving the paradox of stasis: Models with stabilizing selection explain evolutionary divergence on all time-scales
    • Estes S, Arnold SJ. 2007. Resolving the paradox of stasis: models with stabilizing selection explain evolutionary divergence on all time-scales. Am Nat. 169:227-244.
    • (2007) Am Nat. , vol.169 , pp. 227-244
    • Estes, S.1    Arnold, S.J.2
  • 20
    • 4944245629 scopus 로고    scopus 로고
    • Population genetic variation in gene expression is associated with phenotypic variation in Saccharomyces cerevisiae
    • Fay J, McCullough H, Sniegowski P, Eisen M. 2004. Population genetic variation in gene expression is associated with phenotypic variation in Saccharomyces cerevisiae. Genome Biol. 5:R26.
    • (2004) Genome Biol. , vol.5 , pp. R26
    • Fay, J.1    McCullough, H.2    Sniegowski, P.3    Eisen, M.4
  • 22
    • 84860153608 scopus 로고    scopus 로고
    • Using genomic tools to study regulatory evolution
    • Gilad Y. 2012. Using genomic tools to study regulatory evolution. Methods Mol Biol. 856:335-361.
    • (2012) Methods Mol Biol. , vol.856 , pp. 335-361
    • Gilad, Y.1
  • 23
    • 84859208133 scopus 로고    scopus 로고
    • Contrasting properties of gene-specific regulatory, coding, and copy number mutations in Saccharomyces cerevisiae: Frequency, effects, and dominance
    • Gruber JD, Vogel K, Kalay G, Wittkopp PJ. 2012. Contrasting properties of gene-specific regulatory, coding, and copy number mutations in Saccharomyces cerevisiae: frequency, effects, and dominance. PLoS Genet. 8:e1002497.
    • (2012) PLoS Genet , vol.8
    • Gruber, J.D.1    Vogel, K.2    Kalay, G.3    Wittkopp, P.J.4
  • 24
    • 0036578654 scopus 로고    scopus 로고
    • Topological and causal structure of the yeast transcriptional regulatory network
    • Guelzim N, Bottani S, Bourgine P, Kepes F. 2002. Topological and causal structure of the yeast transcriptional regulatory network. Nat Genet. 31:60-63.
    • (2002) Nat Genet , vol.31 , pp. 60-63
    • Guelzim, N.1    Bottani, S.2    Bourgine, P.3    Kepes, F.4
  • 25
    • 84883250225 scopus 로고    scopus 로고
    • The rate and effects of spontaneous mutation on fitness traits in the social amoeba, Dictyostelium discoideum
    • Hall DW, Fox S, Kuzdzal-Fick JJ, Strassmann JE, Queller DC. 2013. The rate and effects of spontaneous mutation on fitness traits in the social amoeba, Dictyostelium discoideum. G3 3:1115-1127.
    • (2013) G3 , vol.3 , pp. 1115-1127
    • Hall, D.W.1    Fox, S.2    Kuzdzal-Fick, J.J.3    Strassmann, J.E.4    Queller, D.C.5
  • 26
    • 0023136661 scopus 로고
    • Regulatory and structural genes for lysosomes of mice
    • Hammer MF, Wilson AC. 1987. Regulatory and structural genes for lysosomes of mice. Genetics 115:521-533.
    • (1987) Genetics , vol.115 , pp. 521-533
    • Hammer, M.F.1    Wilson, A.C.2
  • 28
    • 84879515443 scopus 로고    scopus 로고
    • The ability of flux balance analysis to predict evolution of central metabolism scales with the initial distance to the optimum
    • Harcombe WR, Delaney NF, Leiby N, Klitgord N, Marx CJ. 2013. The ability of flux balance analysis to predict evolution of central metabolism scales with the initial distance to the optimum. PLoS Comput Biol. 9:e1003091.
    • (2013) PLoS Comput Biol. , vol.9
    • Harcombe, W.R.1    Delaney, N.F.2    Leiby, N.3    Klitgord, N.4    Marx, C.J.5
  • 29
    • 84901465749 scopus 로고    scopus 로고
    • The genotype-phenotype map of yeast complex traits: Basic parameters and the role of natural selection
    • Ho W-C, Zhang J. 2014. The genotype-phenotype map of yeast complex traits: basic parameters and the role of natural selection. Mol Biol EVol. 31:1568-1580.
    • (2014) Mol Biol EVol. , vol.31 , pp. 1568-1580
    • Ho, W.-C.1    Zhang, J.2
  • 30
    • 84876022337 scopus 로고    scopus 로고
    • Abundant gene-by-environment interactions in gene expression reaction norms to copper within Saccharomyces cerevisiae
    • Hodgins-Davis A, Adomas AB, Warringer J, Townsend JP. 2012. Abundant gene-by-environment interactions in gene expression reaction norms to copper within Saccharomyces cerevisiae. Genome Biol EVol. 4:1061-1079.
    • (2012) Genome Biol EVol. , vol.4 , pp. 1061-1079
    • Hodgins-Davis, A.1    Adomas, A.B.2    Warringer, J.3    Townsend, J.P.4
  • 31
    • 0034616930 scopus 로고    scopus 로고
    • Functional discovery via a compendium of expression profiles
    • Hughes TR, et al. 2000. Functional discovery via a compendium of expression profiles. Cell 102:109-126.
    • (2000) Cell , vol.102 , pp. 109-126
    • Hughes, T.R.1
  • 32
    • 46249106059 scopus 로고    scopus 로고
    • Gene expression variation in African and European populations of Drosophila melanogaster
    • Hutter S, Saminadin-Peter SS, Stephan W, Parsch J. 2008. Gene expression variation in African and European populations of Drosophila melanogaster. Genome Biol. 9:R12.11-R12.15.
    • (2008) Genome Biol. , vol.9 , pp. R1211-R1215
    • Hutter, S.1    Saminadin-Peter, S.S.2    Stephan, W.3    Parsch, J.4
  • 33
    • 84877748807 scopus 로고    scopus 로고
    • Interspecific divergence of transcription networks along lines of genetic variance in Drosophila: Dimensionality, evolvability, and constraint
    • Innocenti P, Chenoweth S. 2013. Interspecific divergence of transcription networks along lines of genetic variance in Drosophila: dimensionality, evolvability, and constraint. Mol Biol EVol. 30: 1358-1367.
    • (2013) Mol Biol EVol. , vol.30 , pp. 1358-1367
    • Innocenti, P.1    Chenoweth, S.2
  • 34
    • 31344442812 scopus 로고    scopus 로고
    • Theoretical models of selection and mutation on quantitative traits
    • Johnson T, Barton N. 2005. Theoretical models of selection and mutation on quantitative traits. Philos Trans R Soc Lond B Biol Sci. 360: 1411-1425.
    • (2005) Philos Trans R Soc Lond B Biol Sci. , vol.360 , pp. 1411-1425
    • Johnson, T.1    Barton, N.2
  • 35
    • 22144440528 scopus 로고    scopus 로고
    • Toward a neutral evolutionary model of gene expression
    • Khaitovich P, Paabo S, Weiss G. 2005. Toward a neutral evolutionary model of gene expression. Genetics 170:929-939.
    • (2005) Genetics , vol.170 , pp. 929-939
    • Khaitovich, P.1    Paabo, S.2    Weiss, G.3
  • 36
    • 0016669094 scopus 로고
    • Evolution at 2 levels in humans and chimpanzees
    • King MC, Wilson AC. 1975. Evolution at 2 levels in humans and chimpanzees. Science 188:107-116.
    • (1975) Science , vol.188 , pp. 107-116
    • King, M.C.1    Wilson, A.C.2
  • 37
    • 0001503634 scopus 로고
    • Simple model for balance between selection and mutation
    • Kingman JFC. 1978. Simple model for balance between selection and mutation. J Appl Probab. 15:1-12.
    • (1978) J Appl Probab. , vol.15 , pp. 1-12
    • Kingman, J.F.C.1
  • 38
    • 79951910307 scopus 로고    scopus 로고
    • Phenotypic selection in natural populations: What limits directional selection?
    • Kingsolver JG, Diamond SE. 2011. Phenotypic selection in natural populations: what limits directional selection? Am Nat. 177: 346-357.
    • (2011) Am Nat. , vol.177 , pp. 346-357
    • Kingsolver, J.G.1    Diamond, S.E.2
  • 40
    • 0037224621 scopus 로고    scopus 로고
    • Direct estimates of human per nucleotide mutation rates at 20 loci causing Mendelian diseases
    • Kondrashov AS 2003. Direct estimates of human per nucleotide mutation rates at 20 loci causing Mendelian diseases. Hum Mutat. 21: 12-27.
    • (2003) Hum Mutat. , vol.21 , pp. 12-27
    • Kondrashov, A.S.1
  • 41
    • 0017144189 scopus 로고
    • Natural selection and random genetic drift in phenotypic evolution
    • Lande R. 1976. Natural selection and random genetic drift in phenotypic evolution. Evolution 30:314-334.
    • (1976) Evolution , vol.30 , pp. 314-334
    • Lande, R.1
  • 42
  • 43
    • 84876371050 scopus 로고    scopus 로고
    • Genomic background and generation time influence deleterious mutation rates in Daphnia
    • Latta LC, Morgan KK, Weaver CS, Allen D, Schaack S, Lynch M. 2013. Genomic background and generation time influence deleterious mutation rates in Daphnia. Genetics 193:539.
    • (2013) Genetics , vol.193 , pp. 539
    • Latta, L.C.1    Morgan, K.K.2    Weaver, C.S.3    Allen, D.4    Schaack, S.5    Lynch, M.6
  • 44
    • 79959478938 scopus 로고    scopus 로고
    • Approximate Bayesian analysis of Drosophila melanogaster polymorphism data reveals a recent colonization of Southeast Asia
    • Laurent SJY, Werzner A, Excoffier L, Stephan W. 2011. Approximate Bayesian analysis of Drosophila melanogaster polymorphism data reveals a recent colonization of Southeast Asia. Mol Biol EVol. 28: 2041-2051.
    • (2011) Mol Biol EVol. , vol.28 , pp. 2041-2051
    • Laurent, S.J.Y.1    Werzner, A.2    Excoffier, L.3    Stephan, W.4
  • 45
    • 13244251285 scopus 로고    scopus 로고
    • Rates of divergence in gene expression profiles of primates, mice, and flies: Stabilizing selection and variability among functional categories
    • Lemos B, Meiklejohn CD, Caceres M, Hartl DL. 2005. Rates of divergence in gene expression profiles of primates, mice, and flies: stabilizing selection and variability among functional categories. Evolution 59: 126-137.
    • (2005) Evolution , vol.59 , pp. 126-137
    • Lemos, B.1    Meiklejohn, C.D.2    Caceres, M.3    Hartl, D.L.4
  • 46
    • 0023950868 scopus 로고
    • The rate of polygenic mutation
    • Lynch M. 1988. The rate of polygenic mutation. Genet Res. 51:137-148.
    • (1988) Genet Res. , vol.51 , pp. 137-148
    • Lynch, M.1
  • 47
    • 48249133274 scopus 로고    scopus 로고
    • A genome-wide view of the spectrum of spontaneous mutations in yeast
    • Lynch M, et al. 2008. A genome-wide view of the spectrum of spontaneous mutations in yeast. Proc Natl Acad Sci USA. 105:9272-9277.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 9272-9277
    • Lynch, M.1
  • 48
    • 0001199482 scopus 로고
    • Phenotypic evolution by neutral mutation
    • Lynch M, Hill W. 1986. Phenotypic evolution by neutral mutation. Evolution 40:915-935.
    • (1986) Evolution , vol.40 , pp. 915-935
    • Lynch, M.1    Hill, W.2
  • 50
    • 84890562372 scopus 로고    scopus 로고
    • Epistasis and quantitative traits: Using model organisms to study gene-gene interactions
    • Mackay TFC. 2014. Epistasis and quantitative traits: using model organisms to study gene-gene interactions. Nat Rev Genet. 15:22-33.
    • (2014) Nat Rev Genet , vol.15 , pp. 22-33
    • Mackay, T.F.C.1
  • 51
    • 79952129813 scopus 로고    scopus 로고
    • Outcrossing, mitotic recombination, and life-history trade-offs shape genome evolution in Saccharomyces cerevisiae
    • Magwene PM, Kayikci O, Granek JA, Reininga JM, Scholl Z, Murray D. 2011. Outcrossing, mitotic recombination, and life-history trade-offs shape genome evolution in Saccharomyces cerevisiae. Proc Natl Acad Sci USA. 108:1987-1992.
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 1987-1992
    • Magwene, P.M.1    Kayikci, O.2    Granek, J.A.3    Reininga, J.M.4    Scholl, Z.5    Murray, D.6
  • 52
    • 84863537088 scopus 로고    scopus 로고
    • Predictive regulatory models in Drosophila melanogaster by integrative inference of transcriptional networks
    • Marbach D, Roy S, Ay F, Meyer PE, Candeias R, Kahveci T, Bristow CA, Kellis M. 2012. Predictive regulatory models in Drosophila melanogaster by integrative inference of transcriptional networks. Genome Res. 22:1334-1349.
    • (2012) Genome Res. , vol.22 , pp. 1334-1349
    • Marbach, D.1    Roy, S.2    Ay, F.3    Meyer, P.E.4    Candeias, R.5    Kahveci, T.6    Bristow, C.A.7    Kellis, M.8
  • 53
    • 84930221731 scopus 로고    scopus 로고
    • Selection for robustness constrains variation in a yeast promoter
    • Access published March 16, 2015
    • Metzger B, Yuan D, Gruber J, Duveau F, Wittkopp P. 2015. Selection for robustness constrains variation in a yeast promoter. Nature Advance Access published March 16, 2015, doi:10.1038/nature14244.
    • (2015) Nature Advance
    • Metzger, B.1    Yuan, D.2    Gruber, J.3    Duveau, F.4    Wittkopp, P.5
  • 54
    • 79961041294 scopus 로고    scopus 로고
    • Mutation rates and intraspecific divergence of the mitochondrial genome of Pristionchus pacificus
    • Molnar RI, Bartelmes G, Dinkelacker I, Witte H, Sommer RJ. 2011. Mutation rates and intraspecific divergence of the mitochondrial genome of Pristionchus pacificus. Mol Biol EVol. 28:2317-2326.
    • (2011) Mol Biol EVol. , vol.28 , pp. 2317-2326
    • Molnar, R.I.1    Bartelmes, G.2    Dinkelacker, I.3    Witte, H.4    Sommer, R.J.5
  • 55
    • 84870709677 scopus 로고    scopus 로고
    • Estimate of the spontaneous mutation rate in Chlamydomonas reinhardtii
    • Ness RW, Morgan AD, Colegrave N, Keightley PD. 2012. Estimate of the spontaneous mutation rate in Chlamydomonas reinhardtii. Genetics 192:1447-1454.
    • (2012) Genetics , vol.192 , pp. 1447-1454
    • Ness, R.W.1    Morgan, A.D.2    Colegrave, N.3    Keightley, P.D.4
  • 56
    • 0017220894 scopus 로고
    • Role of very slightly deleterious mutations in molecular evolution and polymorphism
    • Ohta T. 1976. Role of very slightly deleterious mutations in molecular evolution and polymorphism. Theor Popul Biol. 10:254-275.
    • (1976) Theor Popul Biol. , vol.10 , pp. 254-275
    • Ohta, T.1
  • 57
    • 0001654122 scopus 로고    scopus 로고
    • Development of neutral and nearly neutral theories
    • Ohta T, Gillespie JH. 1996. Development of neutral and nearly neutral theories. Theor Popul Biol. 49:128-142.
    • (1996) Theor Popul Biol. , vol.49 , pp. 128-142
    • Ohta, T.1    Gillespie, J.H.2
  • 58
    • 0034536680 scopus 로고    scopus 로고
    • Detecting the undetected: Estimating the total number of loci underlying a quantitative trait
    • Otto SP, Jones CD. 2000. Detecting the undetected: estimating the total number of loci underlying a quantitative trait. Genetics 156: 2093-2107.
    • (2000) Genetics , vol.156 , pp. 2093-2107
    • Otto, S.P.1    Jones, C.D.2
  • 61
    • 0037313182 scopus 로고    scopus 로고
    • Evolution of gene expression in the Drosophila melanogaster subgroup
    • Rifkin S, Kim J, White K. 2003. Evolution of gene expression in the Drosophila melanogaster subgroup. Nat Genet. 33:138-144.
    • (2003) Nat Genet , vol.33 , pp. 138-144
    • Rifkin, S.1    Kim, J.2    White, K.3
  • 62
    • 27744499137 scopus 로고    scopus 로고
    • A mutation accumulation assay reveals a broad capacity for rapid evolution of gene expression
    • Rifkin SA, Houle D, Kim J, White KP. 2005. A mutation accumulation assay reveals a broad capacity for rapid evolution of gene expression. Nature 438:220-223.
    • (2005) Nature , vol.438 , pp. 220-223
    • Rifkin, S.A.1    Houle, D.2    Kim, J.3    White, K.P.4
  • 63
    • 77957942349 scopus 로고    scopus 로고
    • Selection at linked sites shapes heritable phenotypic variation in C. elegans
    • Rockman MV, Skrovanek SS, Kruglyak L. 2010. Selection at linked sites shapes heritable phenotypic variation in C. elegans. Science 330: 372-376.
    • (2010) Science , vol.330 , pp. 372-376
    • Rockman, M.V.1    Skrovanek, S.S.2    Kruglyak, L.3
  • 64
    • 43049094834 scopus 로고    scopus 로고
    • Fitness effects of mutation accumulation in a natural outbred population of wild radish (Raphanus raphanistrum): Comparison of field and greenhouse environments
    • Roles AJ, Conner JK. 2008. Fitness effects of mutation accumulation in a natural outbred population of wild radish (Raphanus raphanistrum): comparison of field and greenhouse environments. Evolution 62:1066-1075.
    • (2008) Evolution , vol.62 , pp. 1066-1075
    • Roles, A.J.1    Conner, J.K.2
  • 67
    • 43249129715 scopus 로고    scopus 로고
    • Gene-environment interaction in yeast gene expression
    • Smith E, Kruglyak L. 2008. Gene-environment interaction in yeast gene expression. PLoS Biol. 6:810-824.
    • (2008) PLoS Biol. , vol.6 , pp. 810-824
    • Smith, E.1    Kruglyak, L.2
  • 68
    • 0034251814 scopus 로고    scopus 로고
    • Perspective: Evolutionary developmental biology and the problem of variation
    • Stern DL 2000. Perspective: evolutionary developmental biology and the problem of variation. Evolution 54:1079-1091.
    • (2000) Evolution , vol.54 , pp. 1079-1091
    • Stern, D.L.1
  • 69
    • 51249121392 scopus 로고    scopus 로고
    • Estimating nonlinear selection gradients using quadratic regression coefficients: Double or nothing?
    • Stinchcombe JR, Agrawal AF, Hohenlohe PA, Arnold SJ, Blows MW. 2008. Estimating nonlinear selection gradients using quadratic regression coefficients: double or nothing? Evolution 62:2435-2440.
    • (2008) Evolution , vol.62 , pp. 2435-2440
    • Stinchcombe, J.R.1    Agrawal, A.F.2    Hohenlohe, P.A.3    Arnold, S.J.4    Blows, M.W.5
  • 70
    • 84901599270 scopus 로고    scopus 로고
    • Genetic interactions involving five or more genes contribute to a complex trait in yeast
    • Taylor MB, Ehrenreich IM. 2014. Genetic interactions involving five or more genes contribute to a complex trait in yeast. PLoS Genet. 10: e1004324.
    • (2014) PLoS Genet , vol.10
    • Taylor, M.B.1    Ehrenreich, I.M.2
  • 71
    • 0037572260 scopus 로고    scopus 로고
    • Population genetic variation in genome-wide gene expression
    • Townsend J, Cavalieri D, Hartl D. 2003. Population genetic variation in genome-wide gene expression. Mol Cell Biol. 20:955-963.
    • (2003) Mol Cell Biol. , vol.20 , pp. 955-963
    • Townsend, J.1    Cavalieri, D.2    Hartl, D.3
  • 72
    • 0037975700 scopus 로고    scopus 로고
    • Bayesian analysis of gene expression levels: Statistical quantification of relative mRNA level across multiple strains or treatments
    • 3RESEARCH0071
    • Townsend JP, Hartl DL. 2002. Bayesian analysis of gene expression levels: statistical quantification of relative mRNA level across multiple strains or treatments. Genome Biol. 3RESEARCH0071.
    • (2002) Genome Biol.
    • Townsend, J.P.1    Hartl, D.L.2
  • 73
    • 0021419667 scopus 로고
    • Heritable genetic variation via mutation selection balance - Lerch's zeta meets the abdominal bristle
    • Turelli M. 1984. Heritable genetic variation via mutation selection balance - Lerch's zeta meets the abdominal bristle. Theor Popul Biol. 25: 138-193.
    • (1984) Theor Popul Biol. , vol.25 , pp. 138-193
    • Turelli, M.1
  • 74
    • 77954225714 scopus 로고    scopus 로고
    • Genome-wide gene expression regulation as a function of genotype and age in C. elegans
    • Vinuela A, Snoek LB, Riksen JAG, Kammenga JE. 2010. Genome-wide gene expression regulation as a function of genotype and age in C. elegans. Genome Res. 20:929-937.
    • (2010) Genome Res. , vol.20 , pp. 929-937
    • Vinuela, A.1    Snoek, L.B.2    Riksen, J.A.G.3    Kammenga, J.E.4
  • 75
    • 84869117854 scopus 로고    scopus 로고
    • Aging uncouples heritability and expression-QTL in Caenorhabditis elegans
    • Vinuela A, Snoek LB, Riksen JAG, Kammenga JE. 2012. Aging uncouples heritability and expression-QTL in Caenorhabditis elegans. G3 2: 597-605.
    • (2012) G3 , vol.2 , pp. 597-605
    • Vinuela, A.1    Snoek, L.B.2    Riksen, J.A.G.3    Kammenga, J.E.4
  • 76
    • 34249775493 scopus 로고    scopus 로고
    • Energy costs constrain the evolution of gene expression
    • Wagner A. 2007. Energy costs constrain the evolution of gene expression. J Exp Zool B Mol Dev EVol. 308B:322-324.
    • (2007) J Exp Zool B Mol Dev EVol. , vol.308 B , pp. 322-324
    • Wagner, A.1
  • 77
    • 76249110585 scopus 로고    scopus 로고
    • Abundant genetic variation + strong selection = multivariate genetic constraints. A geometric view of adaptation
    • Walsh B, Blows MW. 2008. Abundant genetic variation + strong selection = multivariate genetic constraints. A geometric view of adaptation. Ann Rev Ecol Syst. 4.0:41-59.
    • (2008) Ann Rev Ecol Syst. , vol.4 , pp. 41-59
    • Walsh, B.1    Blows, M.W.2
  • 78
    • 84859984293 scopus 로고    scopus 로고
    • A selection index for gene expression evolution and its application to the divergence between humans and chimpanzees
    • Warnefors M, Eyre-Walker A. 2012. A selection index for gene expression evolution and its application to the divergence between humans and chimpanzees. PLoS One 7:7.
    • (2012) PLoS One , vol.7 , pp. 7
    • Warnefors, M.1    Eyre-Walker, A.2
  • 80
    • 0000730822 scopus 로고
    • 2 types of molecular evolution - Evidence from studies of interspecific hybridization
    • Wilson AC, Maxson LR, Sarich VM. 1974. 2 types of molecular evolution - evidence from studies of interspecific hybridization. Proc Natl Acad Sci USA. 71:2843-2847.
    • (1974) Proc Natl Acad Sci USA , vol.71 , pp. 2843-2847
    • Wilson, A.C.1    Maxson, L.R.2    Sarich, V.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.