The Ability of Flux Balance Analysis to Predict Evolution of Central Metabolism Scales with the Initial Distance to the Optimum

PLoS Computational Biology

Volumn 9, Issue 6, 2013, Pages

  Harcombe, William R ^a   Delaney, Nigel F ^a,d   Leiby, Nicholas ^a   Klitgord, Niels ^b,e   Marx, Christopher J ^a,c  

^a HARVARD UNIVERSITY   (United States)

^b BOSTON UNIVERSITY   (United States)

^c HARVARD UNIVERSITY   (United States)

^d MASSACHUSETTS GENERAL HOSPITAL   (United States)

^e LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ESCHERICHIA COLI; GLUCOSE; METABOLISM; PHYSIOLOGY;

13-C LABELING; CENTRAL METABOLISMS; FLUX BALANCE ANALYSIS; FLUX DISTRIBUTIONS; INITIAL DISTANCE; INTERNAL FLUXES; METABOLIC FLUX; MULTIPLE CRITERIA; OPTIMALITY; OPTIMALITY CRITERIA;

FORECASTING;

CARBON 13; GLUCOSE; LACTIC ACID;

ARTICLE; BACTERIAL GROWTH; BACTERIAL METABOLISM; BACTERIAL STRAIN; CONTROLLED STUDY; CULTURE MEDIUM; ESCHERICHIA COLI; FLUX BALANCE ANALYSIS; GENOME ANALYSIS; ISOTOPE LABELING; METABOLIC PARAMETERS; METABOLIC RATE; METABOLISM; NONHUMAN; PREDICTION; STOICHIOMETRY;

ESCHERICHIA COLI;

EID: 84879515443     PISSN: 1553734X     EISSN: 15537358     Source Type: Journal    
DOI: 10.1371/journal.pcbi.1003091     Document Type: Article

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