메뉴 건너뛰기




Volumn 360, Issue 1459, 2005, Pages 1411-1425

Theoretical models of selection and mutation on quantitative traits

Author keywords

Mutation; Mutation selection balance; Pleiotropy; Polygenic variation; Quantitative genetics

Indexed keywords

GENETIC VARIATION;

EID: 31344442812     PISSN: 09628436     EISSN: None     Source Type: Journal    
DOI: 10.1098/rstb.2005.1667     Document Type: Review
Times cited : (256)

References (111)
  • 1
    • 0022828323 scopus 로고
    • Molecular population genetics of the alcohol dehydrogenase region of Drosophila melanogaster
    • Aquadro, C. F., Dene, S. F., Bland, M. M., Langley, C. H. & Laurie-Ahlberg, C. C. 1986 Molecular population genetics of the alcohol dehydrogenase region of Drosophila melanogaster. Genetics 114, 1165-1190.
    • (1986) Genetics , vol.114 , pp. 1165-1190
    • Aquadro, C.F.1    Dene, S.F.2    Bland, M.M.3    Langley, C.H.4    Laurie-Ahlberg, C.C.5
  • 2
    • 31344463319 scopus 로고
    • The maintenance of polygenic variation through a balance between mutation and stabilising selection
    • Barton, N. H. 1986 The maintenance of polygenic variation through a balance between mutation and stabilising selection. Genet. Res. 54, 59-77.
    • (1986) Genet. Res. , vol.54 , pp. 59-77
    • Barton, N.H.1
  • 3
    • 0025259533 scopus 로고
    • Pleiotropic models of quantitative variation
    • Barton, N. H. 1990 Pleiotropic models of quantitative variation. Genetics 124, 777-782.
    • (1990) Genetics , vol.124 , pp. 777-782
    • Barton, N.H.1
  • 4
    • 0033374429 scopus 로고    scopus 로고
    • Clines in polygenic traits
    • Barton, N. H. 1999 Clines in polygenic traits. Genet. Res. 74, 223-236.
    • (1999) Genet. Res. , vol.74 , pp. 223-236
    • Barton, N.H.1
  • 5
    • 0036245475 scopus 로고    scopus 로고
    • Understanding quantitative genetic variation
    • Barton, N. H. & Keightley, P. D. 2002 Understanding quantitative genetic variation. Nat. Rev. Genet. 3, 11-21.
    • (2002) Nat. Rev. Genet. , vol.3 , pp. 11-21
    • Barton, N.H.1    Keightley, P.D.2
  • 6
    • 0024792701 scopus 로고
    • Evolutionary quantitative genetics: How little do we know?
    • Barton, N. H. & Turelli, M. 1989 Evolutionary quantitative genetics: How little do we know? Ann. Rev. Genet. 23, 337-370.
    • (1989) Ann. Rev. Genet. , vol.23 , pp. 337-370
    • Barton, N.H.1    Turelli, M.2
  • 7
    • 7344226239 scopus 로고    scopus 로고
    • Mathematical properties of mutation-selection models
    • Bürger, R. 1998 Mathematical properties of mutation-selection models. Genetica 102/103, 279-298.
    • (1998) Genetica , vol.102-103 , pp. 279-298
    • Bürger, R.1
  • 8
    • 0344993925 scopus 로고    scopus 로고
    • Evolution of genetic variability and the advantage of sex and recombination in changing environments
    • Bürger, R. 1999 Evolution of genetic variability and the advantage of sex and recombination in changing environments. Genetics 153, 1055-1069.
    • (1999) Genetics , vol.153 , pp. 1055-1069
    • Bürger, R.1
  • 10
    • 3843098318 scopus 로고    scopus 로고
    • The effects of intraspecific competition and stabilizing selection on a polygenic trait
    • Bürger, R. & Gimelfarb, A. 2004 The effects of intraspecific competition and stabilizing selection on a polygenic trait. Genetics 167, 1425-1443.
    • (2004) Genetics , vol.167 , pp. 1425-1443
    • Bürger, R.1    Gimelfarb, A.2
  • 11
    • 0027945336 scopus 로고
    • A pleiotropic nonadditive model of variation in quantitative traits
    • Caballero, A. & Keightley, P. D. 1994 A pleiotropic nonadditive model of variation in quantitative traits. Genetics 138, 883-900.
    • (1994) Genetics , vol.138 , pp. 883-900
    • Caballero, A.1    Keightley, P.D.2
  • 12
    • 0031265414 scopus 로고    scopus 로고
    • Average dominance for polygenes: Drawbacks of regression estimates
    • Caballero, A., Keightley, P. D. & Turelli, M. 1997 Average dominance for polygenes: Drawbacks of regression estimates. Genetics 147, 1487-1490.
    • (1997) Genetics , vol.147 , pp. 1487-1490
    • Caballero, A.1    Keightley, P.D.2    Turelli, M.3
  • 13
    • 0035931911 scopus 로고    scopus 로고
    • Chance and necessity: The evolution of morphological complexity and diversity
    • Carroll, S. B. 2001 Chance and necessity: the evolution of morphological complexity and diversity. Nature 409, 1102-1109.
    • (2001) Nature , vol.409 , pp. 1102-1109
    • Carroll, S.B.1
  • 14
    • 0029104835 scopus 로고
    • Genetic variability of plant characters in the partial inbreeder Collinsia Heterophylla (Scrophulariaceae)
    • Charlesworth, D. & Mayer, S. 1995 Genetic variability of plant characters in the partial inbreeder Collinsia Heterophylla (Scrophulariaceae). Am. J. Bot. 82, 112-120.
    • (1995) Am. J. Bot. , vol.82 , pp. 112-120
    • Charlesworth, D.1    Mayer, S.2
  • 18
    • 3042758677 scopus 로고    scopus 로고
    • 100 Generations of selection for oil and protein in corn
    • Dudley, J. W. & Lambert, R. J. 2004 100 generations of selection for oil and protein in corn. Plant Breeding Rev. 24, 79-110.
    • (2004) Plant Breeding Rev. , vol.24 , pp. 79-110
    • Dudley, J.W.1    Lambert, R.J.2
  • 19
    • 0003315911 scopus 로고
    • Natural selection in the wild
    • Princeton, NJ: Princeton University Press
    • Endler, J. A. 1986 Natural selection in the wild. Monographs in population biology, 21. Princeton, NJ: Princeton University Press.
    • (1986) Monographs in Population Biology , pp. 21
    • Endler, J.A.1
  • 20
    • 0033611501 scopus 로고    scopus 로고
    • High genomic deleterious mutation rates in hominids
    • Eyre-Walker, A. & Keightley, P. D. 1999 High genomic deleterious mutation rates in hominids. Nature 397, 344-347.
    • (1999) Nature , vol.397 , pp. 344-347
    • Eyre-Walker, A.1    Keightley, P.D.2
  • 21
    • 0018632320 scopus 로고
    • Excursions along the interface between disruptive and stabilising selection
    • Felsenstein, J. 1979 Excursions along the interface between disruptive and stabilising selection. Genetics 93, 773-795.
    • (1979) Genetics , vol.93 , pp. 773-795
    • Felsenstein, J.1
  • 22
    • 84971185409 scopus 로고
    • The correlation between relatives on the supposition of Mendelian inheritance
    • Fisher, R. A. 1918 The correlation between relatives on the supposition of Mendelian inheritance. Proc. R. Soc. (Edinb.) 52, 399-433.
    • (1918) Proc. R. Soc. (Edinb.) , vol.52 , pp. 399-433
    • Fisher, R.A.1
  • 24
    • 0002700414 scopus 로고
    • The founder effect and response to artificial selection in Drosophila
    • ed. A. Robertson, Slough, UK: Commonwealth Agricultural Bureaux
    • Frankham, R. 1980 The founder effect and response to artificial selection in Drosophila. In Selection experiments in laboratory and domestic animals (ed. A. Robertson), pp. 87-90. Slough, UK: Commonwealth Agricultural Bureaux.
    • (1980) Selection Experiments in Laboratory and Domestic Animals , pp. 87-90
    • Frankham, R.1
  • 25
    • 0025084451 scopus 로고
    • Are responses to artificial selection for reproductive fitness characters consistently asymmetrical?
    • Frankham, R. 1990 Are responses to artificial selection for reproductive fitness characters consistently asymmetrical? Genet. Res. 56, 35-42.
    • (1990) Genet. Res. , vol.56 , pp. 35-42
    • Frankham, R.1
  • 26
    • 0033582279 scopus 로고    scopus 로고
    • New estimates of the rates and effects of mildly deleterious mutation in Drosophila melanogaster
    • Fry, J. D., Keightley, P. D., Heinsohn, S. L. & Nuzhdin, S. V. 1999 New estimates of the rates and effects of mildly deleterious mutation in Drosophila melanogaster. Proc. Natl Acad. Sci. USA 96, 574-579.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 574-579
    • Fry, J.D.1    Keightley, P.D.2    Heinsohn, S.L.3    Nuzhdin, S.V.4
  • 28
    • 0027286541 scopus 로고
    • Pleiotropic models of polygenic variation, stabilizing selection, and epistasis
    • Gavrilets, S. & de Jong, G. 1993 Pleiotropic models of polygenic variation, stabilizing selection, and epistasis. Genetics 134, 609-625.
    • (1993) Genetics , vol.134 , pp. 609-625
    • Gavrilets, S.1    De Jong, G.2
  • 29
    • 0037173615 scopus 로고    scopus 로고
    • Functional profiling of the Saccharomyces cerevisiae genome
    • Giaever, G. et al. 2002 Functional profiling of the Saccharomyces cerevisiae genome. Nature 418, 387-391.
    • (2002) Nature , vol.418 , pp. 387-391
    • Giaever, G.1
  • 30
    • 0021180012 scopus 로고
    • Pleiotropic overdominance and the maintenance of genetic variation in polygenic characters
    • Gillespie, J. H. 1984 Pleiotropic overdominance and the maintenance of genetic variation in polygenic characters. Genetics 107, 321-330.
    • (1984) Genetics , vol.107 , pp. 321-330
    • Gillespie, J.H.1
  • 32
    • 0035678847 scopus 로고    scopus 로고
    • Is the population size of a species relevant to its evolution?
    • Gillespie, J. H. 2001 Is the population size of a species relevant to its evolution? Evolution 55, 2161-2169.
    • (2001) Evolution , vol.55 , pp. 2161-2169
    • Gillespie, J.H.1
  • 33
    • 0024495795 scopus 로고
    • Genotype-environment interactions and the maintenance of polygenic variation
    • Gillespie, J. H. & Turelli, M. 1989 Genotype-environment interactions and the maintenance of polygenic variation. Genetics 137, 129-138.
    • (1989) Genetics , vol.137 , pp. 129-138
    • Gillespie, J.H.1    Turelli, M.2
  • 34
    • 0035209177 scopus 로고    scopus 로고
    • Large upward bias in estimation of locus-specific effects from genomewide scans
    • Göring, H. H. H., Terwilliger, J. D. & Blangero, J. 2001 Large upward bias in estimation of locus-specific effects from genomewide scans. Am. J. Hum. Genet. 69, 1357-1369.
    • (2001) Am. J. Hum. Genet. , vol.69 , pp. 1357-1369
    • Göring, H.H.H.1    Terwilliger, J.D.2    Blangero, J.3
  • 36
    • 0026615320 scopus 로고
    • Hybridization of bird species
    • Grant, P. R. & Grant, B. R. 1992 Hybridization of bird species. Science 256, 193-197.
    • (1992) Science , vol.256 , pp. 193-197
    • Grant, P.R.1    Grant, B.R.2
  • 37
    • 0008578712 scopus 로고
    • Polymorphism due to selection of varying direction
    • Haldane, J. B. S. & Jayakar, S. D. 1963 Polymorphism due to selection of varying direction. J. Genet. 58, 237-242.
    • (1963) J. Genet. , vol.58 , pp. 237-242
    • Haldane, J.B.S.1    Jayakar, S.D.2
  • 38
    • 0037402339 scopus 로고    scopus 로고
    • Is modularity necessary for evolvability? Remarks on the relationship between pleiotropy and evolvability
    • Hansen, T. F. 2003 Is modularity necessary for evolvability? Remarks on the relationship between pleiotropy and evolvability. Biosystems 69, 83-94.
    • (2003) Biosystems , vol.69 , pp. 83-94
    • Hansen, T.F.1
  • 39
    • 0024354727 scopus 로고
    • Pleiotropic stabilising selection limits the number of polymorphic loci to at most the number of characters
    • Hastings, A. & Hom, C. L. 1989 Pleiotropic stabilising selection limits the number of polymorphic loci to at most the number of characters. Genetics 122, 459-463.
    • (1989) Genetics , vol.122 , pp. 459-463
    • Hastings, A.1    Hom, C.L.2
  • 41
    • 0002374442 scopus 로고
    • Interrelations of mutation, population size, artificial and natural selection
    • ed. B. S. Weir, E. J. Eisen, M. M. Goodman & G. Namkoong, Sunderland, MA: Sinauer
    • Hill, W. G. & Keightley, P. D. 1988 Interrelations of mutation, population size, artificial and natural selection. In Proceedings of the Second International Conference on Quantitative Genetics (ed. B. S. Weir, E. J. Eisen, M. M. Goodman & G. Namkoong), pp. 57-70. Sunderland, MA: Sinauer.
    • (1988) Proceedings of the Second International Conference on Quantitative Genetics , pp. 57-70
    • Hill, W.G.1    Keightley, P.D.2
  • 43
    • 0026540999 scopus 로고
    • Comparing evolvability and variability of quantitative traits
    • Houle, D. 1992 Comparing evolvability and variability of quantitative traits. Genetics 130, 195-204.
    • (1992) Genetics , vol.130 , pp. 195-204
    • Houle, D.1
  • 44
    • 0030011757 scopus 로고    scopus 로고
    • Comparing mutational variabilities
    • Houle, D., Morikawa, B. & Lynch, M. 1996 Comparing mutational variabilities. Genetics 143, 1467-1483.
    • (1996) Genetics , vol.143 , pp. 1467-1483
    • Houle, D.1    Morikawa, B.2    Lynch, M.3
  • 45
    • 0014921532 scopus 로고
    • The founder effect and response to artificial selection
    • James, J. W. 1971 The founder effect and response to artificial selection. Genet. Res. 16, 241-250.
    • (1971) Genet. Res. , vol.16 , pp. 241-250
    • James, J.W.1
  • 46
    • 0033534015 scopus 로고    scopus 로고
    • The approach to mutation-selection balance in an infinite asexual population, and the evolution of mutation rates
    • doi:10.1098/rspb.1999.0936
    • Johnson, T. 1999 The approach to mutation-selection balance in an infinite asexual population, and the evolution of mutation rates. Proc. R. Soc. B 266, 2389-2397. (doi:10.1098/rspb.1999.0936.)
    • (1999) Proc. R. Soc. B , vol.266 , pp. 2389-2397
    • Johnson, T.1
  • 47
    • 0014731627 scopus 로고
    • Variation in metrical characters in Drosophila populations. II. Natural selection
    • Kearsey, M. J. & Barnes, B. W. 1970 Variation in metrical characters in Drosophila populations. II. Natural selection. Heredity 25, 11-21.
    • (1970) Heredity , vol.25 , pp. 11-21
    • Kearsey, M.J.1    Barnes, B.W.2
  • 48
    • 0030469972 scopus 로고    scopus 로고
    • Nature of deleterious mutation load in Drosophila
    • Keightley, P. D. 1996 Nature of deleterious mutation load in Drosophila. Genetics 144, 1993-1999.
    • (1996) Genetics , vol.144 , pp. 1993-1999
    • Keightley, P.D.1
  • 49
    • 3042792537 scopus 로고    scopus 로고
    • Mutational variation and long-term selection response
    • Keightley, P. D. 2004 Mutational variation and long-term selection response. Plant Breeding Rev. 24, 227-248.
    • (2004) Plant Breeding Rev. , vol.24 , pp. 227-248
    • Keightley, P.D.1
  • 50
    • 0030976617 scopus 로고    scopus 로고
    • Genomic mutation rates for lifetime reproductive output and lifespan in Caenorhabditis elegans
    • Keightley, P. D. & Caballero, A. 1997 Genomic mutation rates for lifetime reproductive output and lifespan in Caenorhabditis elegans. Proc. Natl Acad. Sci. USA 94, 3823-3827.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 3823-3827
    • Keightley, P.D.1    Caballero, A.2
  • 51
    • 0033209826 scopus 로고    scopus 로고
    • Terumi Mukai and the riddle of deleterious mutation rates
    • Keightley, P. D. & Eyre-Walker, A. 1999 Terumi Mukai and the riddle of deleterious mutation rates. Genetics 153, 515-523.
    • (1999) Genetics , vol.153 , pp. 515-523
    • Keightley, P.D.1    Eyre-Walker, A.2
  • 52
    • 0034644576 scopus 로고    scopus 로고
    • Deleterious mutations and the evolution of sex
    • Keightley, P. D. & Eyre-Walker, A. 2000 Deleterious mutations and the evolution of sex. Science 290, 331-334.
    • (2000) Science , vol.290 , pp. 331-334
    • Keightley, P.D.1    Eyre-Walker, A.2
  • 53
    • 0024430144 scopus 로고
    • Quantitative genetic variability maintained by mutation-stabilizing selection balance: Sampling variation and response to subsequent directional selection
    • Keightley, P. D. & Hill, W. G. 1989 Quantitative genetic variability maintained by mutation-stabilizing selection balance: sampling variation and response to subsequent directional selection. Genet. Res. 54, 45-57.
    • (1989) Genet. Res. , vol.54 , pp. 45-57
    • Keightley, P.D.1    Hill, W.G.2
  • 54
    • 0025200474 scopus 로고
    • Variation maintained in quantitative traits with mutation-selection balance: Pleiotropic side-effects on fitness traits
    • Keightley, P. D. & Hill, W. G. 1990 Variation maintained in quantitative traits with mutation-selection balance: pleiotropic side-effects on fitness traits. Proc. R. Soc. B 242, 95-100.
    • (1990) Proc. R. Soc. B , vol.242 , pp. 95-100
    • Keightley, P.D.1    Hill, W.G.2
  • 55
    • 0030053805 scopus 로고    scopus 로고
    • A genetic map of quantitative trait loci for body weight in the mouse
    • Keightley, P. D., Hardge, T., May, L. & Bulfield, G. 1996 A genetic map of quantitative trait loci for body weight in the mouse. Genetics 142, 227-235.
    • (1996) Genetics , vol.142 , pp. 227-235
    • Keightley, P.D.1    Hardge, T.2    May, L.3    Bulfield, G.4
  • 56
    • 0031902920 scopus 로고    scopus 로고
    • Inbreeding and its fitness effects in an insular population of song sparrows (Melospiza melodia)
    • Keller, L. F. 1998 Inbreeding and its fitness effects in an insular population of song sparrows (Melospiza melodia). Evolution 52, 240-250.
    • (1998) Evolution , vol.52 , pp. 240-250
    • Keller, L.F.1
  • 57
    • 0013802404 scopus 로고
    • A stochastic model concerning the maintenance of genetic variability in quantitative characters
    • Kimura, M. 1965 A stochastic model concerning the maintenance of genetic variability in quantitative characters. Proc. Natl Acad. Sci. USA 54, 731-736.
    • (1965) Proc. Natl. Acad. Sci. USA , vol.54 , pp. 731-736
    • Kimura, M.1
  • 58
    • 0014494672 scopus 로고
    • The number of heterozygous nucleotide sites maintained in a finite population due to steady flux of mutation
    • Kimura, M. 1969 The number of heterozygous nucleotide sites maintained in a finite population due to steady flux of mutation. Genetics 61, 893-903.
    • (1969) Genetics , vol.61 , pp. 893-903
    • Kimura, M.1
  • 59
    • 0001503634 scopus 로고
    • A simple model for the balance between selection and mutation
    • Kingman, J. F. C. 1978 A simple model for the balance between selection and mutation. J. Appl. Prob. 15, 1-12.
    • (1978) J. Appl. Prob. , vol.15 , pp. 1-12
    • Kingman, J.F.C.1
  • 61
    • 0026758764 scopus 로고
    • Deleterious mutations, apparent stabilizing selection and the maintenance of quantitative variation
    • Kondrashov, A. S. & Turelli, M. 1992 Deleterious mutations, apparent stabilizing selection and the maintenance of quantitative variation. Genetics 132, 603-618.
    • (1992) Genetics , vol.132 , pp. 603-618
    • Kondrashov, A.S.1    Turelli, M.2
  • 62
    • 0029842292 scopus 로고    scopus 로고
    • High genetic variability under the balance between symmetric mutation and fluctuating stabilizing selection
    • Kondrashov, A. S. & Yampolsky, L. Y. 1996 High genetic variability under the balance between symmetric mutation and fluctuating stabilizing selection. Genet. Res. 68, 157-164.
    • (1996) Genet. Res. , vol.68 , pp. 157-164
    • Kondrashov, A.S.1    Yampolsky, L.Y.2
  • 63
    • 0016814243 scopus 로고
    • The maintenance of genetic variability by mutation in a polygenic character with linked loci
    • Lande, R. 1975 The maintenance of genetic variability by mutation in a polygenic character with linked loci. Genet. Res. 26, 221-235.
    • (1975) Genet. Res. , vol.26 , pp. 221-235
    • Lande, R.1
  • 64
    • 0018946312 scopus 로고
    • The genetic covariance between characters maintained by pleiotropic mutations
    • Lande, R. 1980 The genetic covariance between characters maintained by pleiotropic mutations. Genetics 94, 203-215.
    • (1980) Genetics , vol.94 , pp. 203-215
    • Lande, R.1
  • 65
    • 0001214721 scopus 로고
    • The measurement of selection on correlated characters
    • Lande, R. & Arnold, S. J. 1983 The measurement of selection on correlated characters. Evolution 37, 1210-1226.
    • (1983) Evolution , vol.37 , pp. 1210-1226
    • Lande, R.1    Arnold, S.J.2
  • 66
    • 0025217786 scopus 로고
    • Efficiency of marker-assisted selection in the improvement of quantitative traits
    • Lande, R. & Thompson, R. 1990 Efficiency of marker-assisted selection in the improvement of quantitative traits. Genetics 124, 743-756.
    • (1990) Genetics , vol.124 , pp. 743-756
    • Lande, R.1    Thompson, R.2
  • 67
    • 0027137780 scopus 로고
    • Evolution in vitro: Analysis of a lineage of ribozymes
    • Lehman, N. & Joyce, G. F. 1993 Evolution in vitro: analysis of a lineage of ribozymes. Curr. Biol. 3, 723-734.
    • (1993) Curr. Biol. , vol.3 , pp. 723-734
    • Lehman, N.1    Joyce, G.F.2
  • 68
    • 0031747186 scopus 로고    scopus 로고
    • Two sites in the Delta gene region contribute to naturally occurring variation in bristle number in Drosophila melanogaster
    • Long, A. D., Lyman, R. F., Langley, C. H. & Mackay, T. F. C. 1998 Two sites in the Delta gene region contribute to naturally occurring variation in bristle number in Drosophila melanogaster. Genetics 149, 999-1017.
    • (1998) Genetics , vol.149 , pp. 999-1017
    • Long, A.D.1    Lyman, R.F.2    Langley, C.H.3    Mackay, T.F.C.4
  • 69
    • 0034056305 scopus 로고    scopus 로고
    • Both naturally occurring insertions of transposable elements and intermediate frequency polymorphisms at the achaete scute complex are associated with variation in bristle number in Drosophila melanogaster
    • Long, A. D., Lyman, R. F., Morgan, A. H., Langley, C. H. & Mackay, T. F. C. 2000 Both naturally occurring insertions of transposable elements and intermediate frequency polymorphisms at the achaete scute complex are associated with variation in bristle number in Drosophila melanogaster. Genetics 154, 1255-1269.
    • (2000) Genetics , vol.154 , pp. 1255-1269
    • Long, A.D.1    Lyman, R.F.2    Morgan, A.H.3    Langley, C.H.4    Mackay, T.F.C.5
  • 70
    • 0023950868 scopus 로고
    • The rate of polygenic mutation
    • Lynch, M. 1988 The rate of polygenic mutation. Genet. Res. 51, 137-148.
    • (1988) Genet. Res. , vol.51 , pp. 137-148
    • Lynch, M.1
  • 73
    • 0026525956 scopus 로고
    • Effects of P element insertions on quantitative traits in Drosophila melanogaster
    • Mackay, T. F. C., Lyman, R. F. & Jackson, M. S. 1990 Effects of P element insertions on quantitative traits in Drosophila melanogaster. Genetics 130, 315-332.
    • (1990) Genetics , vol.130 , pp. 315-332
    • Mackay, T.F.C.1    Lyman, R.F.2    Jackson, M.S.3
  • 74
    • 0031714655 scopus 로고    scopus 로고
    • The population genetics of adaptation: The distribution of factors fixed during adaptive evolution
    • Orr, H. A. 1998 The population genetics of adaptation: the distribution of factors fixed during adaptive evolution. Evolution 52, 935-949.
    • (1998) Evolution , vol.52 , pp. 935-949
    • Orr, H.A.1
  • 75
    • 0034025692 scopus 로고    scopus 로고
    • Adaptation and the cost of complexity
    • Orr, H. A. 2000 Adaptation and the cost of complexity. Evolution 54, 13-20.
    • (2000) Evolution , vol.54 , pp. 13-20
    • Orr, H.A.1
  • 76
    • 0027095368 scopus 로고
    • The genetics of adaptation: A reassessment
    • Orr, H. A. & Coyne, J. A. 1992 The genetics of adaptation: a reassessment. Am. Nat. 140, 725-742.
    • (1992) Am. Nat. , vol.140 , pp. 725-742
    • Orr, H.A.1    Coyne, J.A.2
  • 77
    • 1842451461 scopus 로고    scopus 로고
    • Two steps forward, one step back: The pleiotropic effects of favoured alleles
    • doi:10.1098/rspb.2003.2635
    • Otto, S. P. 2004 Two steps forward, one step back: the pleiotropic effects of favoured alleles. Proc. R. Soc. B 271, 705-714. (doi:10.1098/rspb. 2003.2635.)
    • (2004) Proc. R. Soc. B , vol.271 , pp. 705-714
    • Otto, S.P.1
  • 78
    • 0034536680 scopus 로고    scopus 로고
    • Detecting the undetected: Estimating the total number of loci underlying a quantitative trait
    • Otto, S. P. & Jones, C. D. 2000 Detecting the undetected: estimating the total number of loci underlying a quantitative trait. Genetics 156, 2093-2107.
    • (2000) Genetics , vol.156 , pp. 2093-2107
    • Otto, S.P.1    Jones, C.D.2
  • 79
    • 0002795621 scopus 로고
    • Mathematical contributions to the theory of evolution. XI. On the influence of natural selection on the variability and correlation of organs
    • Pearson, K. 1903 Mathematical contributions to the theory of evolution. XI. On the influence of natural selection on the variability and correlation of organs. Phil. Trans. R. Soc. A 200, 1-66.
    • (1903) Phil. Trans. R. Soc. A , vol.200 , pp. 1-66
    • Pearson, K.1
  • 80
    • 0034925447 scopus 로고    scopus 로고
    • Genetic variation for morphological and allozyme variation in relation to population size in Clarkia dudleyana, an endemic annual
    • Podolsky, R. H. 2001 Genetic variation for morphological and allozyme variation in relation to population size in Clarkia dudleyana, an endemic annual. Conserv. Biol. 15, 412-423.
    • (2001) Conserv. Biol. , vol.15 , pp. 412-423
    • Podolsky, R.H.1
  • 81
    • 0036799545 scopus 로고    scopus 로고
    • The allelic architecture of human disease genes: Common disease - Common variant... or not?
    • Pritchard, J. K. & Cox, N. J. 2002 The allelic architecture of human disease genes: common disease - common variant... or not?. Hum. Mol. Genet. 11, 2417-2242.
    • (2002) Hum. Mol. Genet. , vol.11 , pp. 2417-12242
    • Pritchard, J.K.1    Cox, N.J.2
  • 82
    • 0034926475 scopus 로고    scopus 로고
    • How closely correlated are molecular and quantitative measures of genetic variation? A meta-analysis
    • Reed, D. H. & Frankham, R. 2001 How closely correlated are molecular and quantitative measures of genetic variation? A meta-analysis. Evolution 55, 1095-1103.
    • (2001) Evolution , vol.55 , pp. 1095-1103
    • Reed, D.H.1    Frankham, R.2
  • 83
    • 0000099381 scopus 로고
    • Effect of selection against extreme deviants based on deviation or on homozygosis
    • Robertson, A. 1956 Effect of selection against extreme deviants based on deviation or on homozygosis. J. Genet. 54, 236-248.
    • (1956) J. Genet. , vol.54 , pp. 236-248
    • Robertson, A.1
  • 84
    • 0002341199 scopus 로고
    • The nature of quantitative genetic variation
    • ed. R. A. Brink, Madison, WI: University of Wisconsin Press
    • Robertson, A. 1967 The nature of quantitative genetic variation. In Heritage from Mendel (ed. R. A. Brink), pp. 265-280. Madison, WI: University of Wisconsin Press.
    • (1967) Heritage from Mendel , pp. 265-280
    • Robertson, A.1
  • 86
    • 0000722825 scopus 로고
    • The evolution of niche width
    • Roughgarden, J. 1972 The evolution of niche width. Am. Nat. 106, 683-718.
    • (1972) Am. Nat. , vol.106 , pp. 683-718
    • Roughgarden, J.1
  • 87
    • 0028174690 scopus 로고
    • Exploring fitness surfaces
    • Schluter, D. & Nychka, D. 1994 Exploring fitness surfaces. Am. Nat. 143, 597-616.
    • (1994) Am. Nat. , vol.143 , pp. 597-616
    • Schluter, D.1    Nychka, D.2
  • 88
    • 0034698298 scopus 로고    scopus 로고
    • One sequence, two ribozymes: Implications for the emergence of new ribozyme folds
    • Schultes, E. A. & Bartel, D. P. 2000 One sequence, two ribozymes: Implications for the emergence of new ribozyme folds. Science 289, 448-452.
    • (2000) Science , vol.289 , pp. 448-452
    • Schultes, E.A.1    Bartel, D.P.2
  • 89
    • 0034015984 scopus 로고    scopus 로고
    • Spontaneous mutational effects on reproductive traits of Arabidopsis thaliana
    • Shaw, R. G., Byers, D. L. & Darmo, E. 2000 Spontaneous mutational effects on reproductive traits of Arabidopsis thaliana. Genetics 155, 369-378.
    • (2000) Genetics , vol.155 , pp. 369-378
    • Shaw, R.G.1    Byers, D.L.2    Darmo, E.3
  • 90
    • 0018563643 scopus 로고
    • Frequency- and density-dependent selection on a quantitative character
    • Slatkin, M. 1979 Frequency- and density-dependent selection on a quantitative character. Genetics 93, 755-771.
    • (1979) Genetics , vol.93 , pp. 755-771
    • Slatkin, M.1
  • 91
    • 0023275704 scopus 로고
    • Heritable variation and heterozygosity under a balance between mutations and stabilising selection
    • Slatkin, M. 1987 Heritable variation and heterozygosity under a balance between mutations and stabilising selection. Genet. Res. 50, 53-62.
    • (1987) Genet. Res. , vol.50 , pp. 53-62
    • Slatkin, M.1
  • 92
    • 0025232697 scopus 로고
    • The quantitative genetic consequences of pleiotropy under stabilizing and directional selection
    • Slatkin, M. & Frank, S. A. 1990 The quantitative genetic consequences of pleiotropy under stabilizing and directional selection. Genetics 125, 207-213.
    • (1990) Genetics , vol.125 , pp. 207-213
    • Slatkin, M.1    Frank, S.A.2
  • 93
    • 0034251814 scopus 로고    scopus 로고
    • Evolutionary developmental biology and the problem of variation
    • Stern, D. L. 2000 Evolutionary developmental biology and the problem of variation. Evolution 54, 1079-1091.
    • (2000) Evolution , vol.54 , pp. 1079-1091
    • Stern, D.L.1
  • 94
    • 0030128741 scopus 로고    scopus 로고
    • The genetic variance maintained by pleiotropic mutation
    • Tanaka, Y. 1996 The genetic variance maintained by pleiotropic mutation. Theor. Popul. Biol. 49, 211-231.
    • (1996) Theor. Popul. Biol. , vol.49 , pp. 211-231
    • Tanaka, Y.1
  • 95
    • 0026664105 scopus 로고
    • Mosaic analysis gives an estimate of the extent of genomic involvement in the development of the visual system in D. melanogaster
    • Thaker, H. M. & Kankel, D. R. 1992 Mosaic analysis gives an estimate of the extent of genomic involvement in the development of the visual system in D. melanogaster. Genetics 131, 883-894.
    • (1992) Genetics , vol.131 , pp. 883-894
    • Thaker, H.M.1    Kankel, D.R.2
  • 96
    • 0021419667 scopus 로고
    • Heritable genetic variation via mutation selection balance: Lurch's zeta meets the abdominal bristle
    • Turelli, M. 1984 Heritable genetic variation via mutation selection balance: Lurch's zeta meets the abdominal bristle. Theor. Popul. Biol. 25, 138-193.
    • (1984) Theor. Popul. Biol. , vol.25 , pp. 138-193
    • Turelli, M.1
  • 97
    • 0022233074 scopus 로고
    • Effects of pleiotropy on predictions concerning mutation-selection balance for polygenic traits
    • Turelli, M. 1985 Effects of pleiotropy on predictions concerning mutation-selection balance for polygenic traits. Genetics 111, 165-195.
    • (1985) Genetics , vol.111 , pp. 165-195
    • Turelli, M.1
  • 98
    • 1642379258 scopus 로고    scopus 로고
    • Polygenic variation maintained by balancing selection: Pleiotropy, sex-dependent allelic effects and GXE interactions
    • Turelli, M. & Barton, N. H. 2004 Polygenic variation maintained by balancing selection: Pleiotropy, sex-dependent allelic effects and GXE interactions. Genetics 166, 1053-1079.
    • (2004) Genetics , vol.166 , pp. 1053-1079
    • Turelli, M.1    Barton, N.H.2
  • 99
    • 0029661332 scopus 로고    scopus 로고
    • Complex adaptations and the evolution of evolvability
    • Wagner, G. P. & Altenberg, L. 1996 Complex adaptations and the evolution of evolvability. Evolution 50, 967-976.
    • (1996) Evolution , vol.50 , pp. 967-976
    • Wagner, G.P.1    Altenberg, L.2
  • 100
    • 0032549157 scopus 로고    scopus 로고
    • Pleiotropy and the preservation of perfection
    • Waxman, D. & Peck, J. R. 1998 Pleiotropy and the preservation of perfection. Science 279, 1210-1213.
    • (1998) Science , vol.279 , pp. 1210-1213
    • Waxman, D.1    Peck, J.R.2
  • 101
    • 0026513493 scopus 로고
    • How small are the smallest selectable domains of form
    • Weber, K. E. 1992 How small are the smallest selectable domains of form. Genetics 130, 345-353.
    • (1992) Genetics , vol.130 , pp. 345-353
    • Weber, K.E.1
  • 102
    • 0025353575 scopus 로고
    • Increased selection response in larger populations. II. Selection for ethanol vapor resistance in Drosophila melanogaster at two population sizes
    • Weber, K. E. & Diggins, L. T. 1990 Increased selection response in larger populations. II. Selection for ethanol vapor resistance in Drosophila melanogaster at two population sizes. Genetics 125, 585-597.
    • (1990) Genetics , vol.125 , pp. 585-597
    • Weber, K.E.1    Diggins, L.T.2
  • 103
    • 0032819610 scopus 로고    scopus 로고
    • An analysis of polygenes affecting wing shape on chromosome 3 in Drosophila melanogaster
    • Weber, K. et al. 1999 An analysis of polygenes affecting wing shape on chromosome 3 in Drosophila melanogaster. Genetics 153, 773-786.
    • (1999) Genetics , vol.153 , pp. 773-786
    • Weber, K.1
  • 104
    • 0032900475 scopus 로고    scopus 로고
    • The changes in genetic and environmental variance with inbreeding in Drosophila melanogaster
    • Whitlock, M. C. & Fowler, K. 1999 The changes in genetic and environmental variance with inbreeding in Drosophila melanogaster. Genetics 152, 345-353.
    • (1999) Genetics , vol.152 , pp. 345-353
    • Whitlock, M.C.1    Fowler, K.2
  • 105
    • 0043210647 scopus 로고    scopus 로고
    • Scaling of mutational effects in models for pleiotropy
    • Wingreen, N. S., Miller, J. & Cox, E. C. 2003 Scaling of mutational effects in models for pleiotropy. Genetics 164, 1221-1228.
    • (2003) Genetics , vol.164 , pp. 1221-1228
    • Wingreen, N.S.1    Miller, J.2    Cox, E.C.3
  • 106
    • 77951515648 scopus 로고
    • Evolution in populations in approximate equilibrium
    • Wright, S. 1935 Evolution in populations in approximate equilibrium. J. Genet. 30, 257-266.
    • (1935) J. Genet. , vol.30 , pp. 257-266
    • Wright, S.1
  • 107
    • 0018824443 scopus 로고
    • Long-term selection for a quantitative character in large replicate populations of Drosophila melanogaster. I. Response to selection
    • Yoo, B. H. 1980 Long-term selection for a quantitative character in large replicate populations of Drosophila melanogaster. I. Response to selection. Genet. Res. 35, 1-17.
    • (1980) Genet. Res. , vol.35 , pp. 1-17
    • Yoo, B.H.1
  • 108
    • 0036743347 scopus 로고    scopus 로고
    • Joint effects of pleiotropic selection and stabilizing selection on the maintenance of quantitative genetic variation at mutation-selection balance
    • Zhang, X.-S. & Hill, W. G. 2002 Joint effects of pleiotropic selection and stabilizing selection on the maintenance of quantitative genetic variation at mutation-selection balance. Genetics 162, 459-471.
    • (2002) Genetics , vol.162 , pp. 459-471
    • Zhang, X.-S.1    Hill, W.G.2
  • 109
    • 0043286740 scopus 로고    scopus 로고
    • Multivariate stabilizing selection and pleiotropy in the maintenance of quantitative genetic variation
    • Zhang, X.-S. & Hill, W. G. 2003 Multivariate stabilizing selection and pleiotropy in the maintenance of quantitative genetic variation. Evolution 57, 1761-1775.
    • (2003) Evolution , vol.57 , pp. 1761-1775
    • Zhang, X.-S.1    Hill, W.G.2
  • 110
    • 0036259692 scopus 로고    scopus 로고
    • Pleiotropic model of maintenance of quantitative genetic variation at mutation-selection balance
    • Zhang, X.-S., Wang, J. & Hill, W. G. 2002 Pleiotropic model of maintenance of quantitative genetic variation at mutation-selection balance. Genetics 161, 419-433.
    • (2002) Genetics , vol.161 , pp. 419-433
    • Zhang, X.-S.1    Wang, J.2    Hill, W.G.3
  • 111
    • 1642389513 scopus 로고    scopus 로고
    • Influence of dominance, leptokurtosis and pleiotropy of deleterious mutations on quantitative genetic variation at mutation-selection balance
    • Zhang, X.-S., Wang, J. & Hill, W. G. 2004 Influence of dominance, leptokurtosis and pleiotropy of deleterious mutations on quantitative genetic variation at mutation-selection balance. Genetics 166, 597-610.
    • (2004) Genetics , vol.166 , pp. 597-610
    • Zhang, X.-S.1    Wang, J.2    Hill, W.G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.