Inhibition of TGF-β signaling promotes human pancreatic β-cell replication

Diabetes

Volumn 65, Issue 5, 2016, Pages 1208-1218

  Dhawan, Sangeeta ^a   Dirice, Ercument ^b   Kulkarni, Rohit N ^b   Bhushan, Anil ^c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 [4 (1,3 BENZODIOXOL 5 YL) 5 (2 PYRIDINYL) 1H IMIDAZOL 2 YL]BENZAMIDE; CYCLIN DEPENDENT KINASE INHIBITOR 2A; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; 1,3 DIOXOLANE DERIVATIVE; 4-(5-BENZO(1,3)DIOXOL-5-YL-4-PYRIDIN-2-YL-1H-IMIDAZOL-2-YL)BENZAMIDE; BENZAMIDE DERIVATIVE; INSULIN; P16 PROTEIN, HUMAN; SMAD3 PROTEIN, HUMAN; TGFB1 PROTEIN, HUMAN; TRANSFORMING GROWTH FACTOR BETA RECEPTOR; TRANSFORMING GROWTH FACTOR BETA1;

ADULT; ANIMAL EXPERIMENT; ARTICLE; CELL AGING; CELL DIVISION; CELL PROLIFERATION; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; FEMALE; HUMAN; MALE; MOUSE; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; WESTERN BLOTTING; AGONISTS; ANIMAL; ANTAGONISTS AND INHIBITORS; C57BL MOUSE; CELL CULTURE; CYTOLOGY; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; HETEROTOPIC TRANSPLANTATION; METABOLISM; NONOBESE DIABETIC MOUSE; PANCREAS ISLET TRANSPLANTATION; PHYSIOLOGY; REGENERATION; SCID MOUSE; SECRETION (PROCESS); TISSUE BANK; TRANSGENIC MOUSE; XENOGRAFT;

ANIMALS; BENZAMIDES; CELL PROLIFERATION; CELLS, CULTURED; CYCLIN-DEPENDENT KINASE INHIBITOR P16; DIOXOLES; FEMALE; GENE EXPRESSION REGULATION; HUMANS; INSULIN; INSULIN-SECRETING CELLS; ISLETS OF LANGERHANS TRANSPLANTATION; MALE; MICE, INBRED C57BL; MICE, INBRED NOD; MICE, SCID; MICE, TRANSGENIC; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA; REGENERATION; SIGNAL TRANSDUCTION; SMAD3 PROTEIN; TISSUE BANKS; TRANSFORMING GROWTH FACTOR BETA1; TRANSPLANTATION, HETEROLOGOUS; TRANSPLANTATION, HETEROTOPIC;

EID: 84964573479     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db15-1331     Document Type: Article

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