-
1
-
-
0028281773
-
Tissue and plasma concentrations of amidated and glycine-extended glucagon-like peptide I in humans
-
C. Ørskov, L. Rabenhøj, A. Wettergren, H. Kofod, and J. J. Holst, "Tissue and plasma concentrations of amidated and glycine-extended glucagon-like peptide I in humans," Diabetes, vol. 43, no. 4, pp. 535-539, 1994.
-
(1994)
Diabetes
, vol.43
, Issue.4
, pp. 535-539
-
-
Ørskov, C.1
Rabenhøj, L.2
Wettergren, A.3
Kofod, H.4
Holst, J.J.5
-
2
-
-
0037312821
-
The influence of GLP-1 on glucose-stimulated insulin secretion: Effects on β-cell sensitivity in type 2 and nondiabetic subjects
-
L. L. Kjems, J. J. Holst, A. Vølund, and S. Madsbad, "The influence of GLP-1 on glucose-stimulated insulin secretion: effects on β-cell sensitivity in type 2 and nondiabetic subjects," Diabetes, vol. 52, no. 2, pp. 380-386, 2003.
-
(2003)
Diabetes
, vol.52
, Issue.2
, pp. 380-386
-
-
Kjems, L.L.1
Holst, J.J.2
Vølund, A.3
Madsbad, S.4
-
3
-
-
0027215348
-
Dipeptidyl-peptidase IV hydrolyses gastric inhibitory polypeptide, glucagon-like peptide-1(7-36)amide, peptide histidine methionine and is responsible for their degradation in human serum
-
R. Mentlein, B. Gallwitz, and W. E. Schmidt, "Dipeptidyl-peptidase IV hydrolyses gastric inhibitory polypeptide, glucagon-like peptide-1(7-36)amide, peptide histidine methionine and is responsible for their degradation in human serum," European Journal of Biochemistry, vol. 214, no. 3, pp. 829-835, 1993.
-
(1993)
European Journal of Biochemistry
, vol.214
, Issue.3
, pp. 829-835
-
-
Mentlein, R.1
Gallwitz, B.2
Schmidt, W.E.3
-
4
-
-
84890118673
-
Anti-diabetic actions of glucagon-like peptide-1 on pancreatic beta-cells
-
Y.-S. Lee and H.-S. Jun, "Anti-diabetic actions of glucagon-like peptide-1 on pancreatic beta-cells," Metabolism: Clinical and Experimental, vol. 63, no. 1, pp. 9-19, 2014.
-
(2014)
Metabolism: Clinical and Experimental
, vol.63
, Issue.1
, pp. 9-19
-
-
Lee, Y.-S.1
Jun, H.-S.2
-
5
-
-
64149130125
-
Functional pancreatic beta-cell mass: Involvement in type 2 diabetes and therapeutic intervention
-
M. Karaca, C. Magnan, and C. Kargar, "Functional pancreatic beta-cell mass: involvement in type 2 diabetes and therapeutic intervention," Diabetes & Metabolism, vol. 35, no. 2, pp. 77-84, 2009.
-
(2009)
Diabetes & Metabolism
, vol.35
, Issue.2
, pp. 77-84
-
-
Karaca, M.1
Magnan, C.2
Kargar, C.3
-
6
-
-
33644618433
-
The biology of incretin hormones
-
D. J. Drucker, "The biology of incretin hormones," Cell Metabolism, vol. 3, no. 3, pp. 153-165, 2006.
-
(2006)
Cell Metabolism
, vol.3
, Issue.3
, pp. 153-165
-
-
Drucker, D.J.1
-
7
-
-
84906219286
-
Effects of sitagliptin therapy on markers of low-grade inflammation and cell adhesion molecules in patients with type 2 diabetes
-
A. J. Tremblay, B. Lamarche, C. F. Deacon, S. J. Weisnagel, and P. Couture, "Effects of sitagliptin therapy on markers of low-grade inflammation and cell adhesion molecules in patients with type 2 diabetes," Metabolism: Clinical and Experimental, vol. 63, no. 9, pp. 1141-1148, 2014.
-
(2014)
Metabolism: Clinical and Experimental
, vol.63
, Issue.9
, pp. 1141-1148
-
-
Tremblay, A.J.1
Lamarche, B.2
Deacon, C.F.3
Weisnagel, S.J.4
Couture, P.5
-
8
-
-
84928984759
-
Sirtuin 6 expression and inflammatory activity in diabetic atherosclerotic plaques: Effects of incretin treatment
-
M. L. Balestrieri, M. R. Rizzo, M. Barbieri et al., "Sirtuin 6 expression and inflammatory activity in diabetic atherosclerotic plaques: effects of incretin treatment," Diabetes, vol. 64, no. 4, pp. 1395-1406, 2015.
-
(2015)
Diabetes
, vol.64
, Issue.4
, pp. 1395-1406
-
-
Balestrieri, M.L.1
Rizzo, M.R.2
Barbieri, M.3
-
9
-
-
84859867948
-
Clinical use of liraglutide in type 2 diabetes and its effects on cardiovascular risk factors
-
A. Varanasi, P. Patel, A. Makdissi, S. Dhindsa, A. Chaudhuri, and P. Dandona, "Clinical use of liraglutide in type 2 diabetes and its effects on cardiovascular risk factors," Endocrine Practice, vol. 18, no. 2, pp. 140-145, 2012.
-
(2012)
Endocrine Practice
, vol.18
, Issue.2
, pp. 140-145
-
-
Varanasi, A.1
Patel, P.2
Makdissi, A.3
Dhindsa, S.4
Chaudhuri, A.5
Dandona, P.6
-
10
-
-
79959778328
-
Long-acting glucagon-like peptide 1 receptor agonists: A review of their efficacy and tolerability
-
A. J. Garber, "Long-acting glucagon-like peptide 1 receptor agonists: a review of their efficacy and tolerability," Diabetes Care, vol. 34, supplement 2, pp. S279-S284, 2011.
-
(2011)
Diabetes Care
, vol.34
, pp. S279-S284
-
-
Garber, A.J.1
-
11
-
-
84957878858
-
Incretin therapies: Highlighting common features and differences in the modes of action of glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors
-
M. Nauck, "Incretin therapies: highlighting common features and differences in the modes of action of glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors," Diabetes, Obesity & Metabolism, vol. 18, no. 3, pp. 203-216, 2016.
-
(2016)
Diabetes, Obesity & Metabolism
, vol.18
, Issue.3
, pp. 203-216
-
-
Nauck, M.1
-
12
-
-
77951151612
-
Inhibition of monocyte adhesion to endothelial cells and attenuation of atherosclerotic lesion by a glucagon-like peptide-1 receptor agonist, exendin-4
-
M. Arakawa, T. Mita, K. Azuma et al., "Inhibition of monocyte adhesion to endothelial cells and attenuation of atherosclerotic lesion by a glucagon-like peptide-1 receptor agonist, exendin-4," Diabetes, vol. 59, no. 4, pp. 1030-1037, 2010.
-
(2010)
Diabetes
, vol.59
, Issue.4
, pp. 1030-1037
-
-
Arakawa, M.1
Mita, T.2
Azuma, K.3
-
13
-
-
0026775150
-
Expression cloning of the pancreatic β cell receptor for the gluco- incretin hormone glucagon-like peptide 1
-
B. Thorens, "Expression cloning of the pancreatic β cell receptor for the gluco- incretin hormone glucagon-like peptide 1," Proceedings of the National Academy of Sciences of the United States of America, vol. 89, no. 18, pp. 8641-8645, 1992.
-
(1992)
Proceedings of the National Academy of Sciences of the United States of America
, vol.89
, Issue.18
, pp. 8641-8645
-
-
Thorens, B.1
-
14
-
-
84895190840
-
The protective roles of GLP-1R signaling in diabetic nephropathy: Possible mechanism and therapeutic potential
-
H. Fujita, T. Morii, H. Fujishima et al., "The protective roles of GLP-1R signaling in diabetic nephropathy: possible mechanism and therapeutic potential," Kidney International, vol. 85, no. 3, pp. 579-589, 2014.
-
(2014)
Kidney International
, vol.85
, Issue.3
, pp. 579-589
-
-
Fujita, H.1
Morii, T.2
Fujishima, H.3
-
15
-
-
84874626634
-
Pulmonary GLP-1 receptor increases at birth and exogenous GLP-1 receptor agonists augmented surfactant-protein levels in litters from normal and nitrofen-treated pregnant rats
-
M. Romaní-Pérez, V. Outeiriño-Iglesias, M. Gil-Lozano, L. C. González-Matías, F. Mallo, and E. Vigo, "Pulmonary GLP-1 receptor increases at birth and exogenous GLP-1 receptor agonists augmented surfactant-protein levels in litters from normal and nitrofen-treated pregnant rats," Endocrinology, vol. 154, no. 3, pp. 1144-1155, 2013.
-
(2013)
Endocrinology
, vol.154
, Issue.3
, pp. 1144-1155
-
-
Romaní-Pérez, M.1
Outeiriño-Iglesias, V.2
Gil-Lozano, M.3
González-Matías, L.C.4
Mallo, F.5
Vigo, E.6
-
16
-
-
0028867442
-
Distribution of GLP-1 binding sites in the rat brain: Evidence that exendin-4 is a ligand of brain GLP-1 binding sites
-
R. Goke, P. J. Larsen, J. D. Mikkelsen, and S. P. Sheikh, "Distribution of GLP-1 binding sites in the rat brain: evidence that exendin-4 is a ligand of brain GLP-1 binding sites," The European Journal of Neuroscience, vol. 7, no. 11, pp. 2294-2300, 1995.
-
(1995)
The European Journal of Neuroscience
, vol.7
, Issue.11
, pp. 2294-2300
-
-
Goke, R.1
Larsen, P.J.2
Mikkelsen, J.D.3
Sheikh, S.P.4
-
17
-
-
33744996917
-
Glucagon-like peptide-1 inhibits LPS-induced IL-1β production in cultured rat astrocytes
-
T. Iwai, S. Ito, K. Tanimitsu, S. Udagawa, and J.-I. Oka, "Glucagon-like peptide-1 inhibits LPS-induced IL-1β production in cultured rat astrocytes," Neuroscience Research, vol. 55, no. 4, pp. 352-360, 2006.
-
(2006)
Neuroscience Research
, vol.55
, Issue.4
, pp. 352-360
-
-
Iwai, T.1
Ito, S.2
Tanimitsu, K.3
Udagawa, S.4
Oka, J.-I.5
-
18
-
-
84866055251
-
Glucagon-like peptide-1 inhibits adipose tissue macrophage infiltration and inflammation in an obese mouse model of diabetes
-
Y.-S. Lee, M.-S. Park, J.-S. Choung et al., "Glucagon-like peptide-1 inhibits adipose tissue macrophage infiltration and inflammation in an obese mouse model of diabetes," Diabetologia, vol. 55, no. 9, pp. 2456-2468, 2012.
-
(2012)
Diabetologia
, vol.55
, Issue.9
, pp. 2456-2468
-
-
Lee, Y.-S.1
Park, M.-S.2
Choung, J.-S.3
-
19
-
-
79251541159
-
Dipeptidyl peptidase IV inhibitor sitagliptin reduces local inflammation in adipose tissue and in pancreatic islets of obese mice
-
A. D. Dobrian, Q. Ma, J. W. Lindsay et al., "Dipeptidyl peptidase IV inhibitor sitagliptin reduces local inflammation in adipose tissue and in pancreatic islets of obese mice," The American Journal of Physiology - Endocrinology and Metabolism, vol. 300, no. 2, pp. E410-E421, 2011.
-
(2011)
The American Journal of Physiology - Endocrinology and Metabolism
, vol.300
, Issue.2
, pp. E410-E421
-
-
Dobrian, A.D.1
Ma, Q.2
Lindsay, J.W.3
-
20
-
-
84856000294
-
GLP-1, the gut-brain, and brain-periphery axes
-
C. Cabou and R. Burcelin, "GLP-1, the gut-brain, and brain-periphery axes," Review of Diabetic Studies, vol. 8, no. 3, pp. 418-431, 2011.
-
(2011)
Review of Diabetic Studies
, vol.8
, Issue.3
, pp. 418-431
-
-
Cabou, C.1
Burcelin, R.2
-
21
-
-
84910603708
-
Effects of glucagon-like peptide-1 receptor agonists on non-alcoholic fatty liver disease and inflammation
-
X.-C. Wang, A. M. Gusdon, H. Liu, and S. Qu, "Effects of glucagon-like peptide-1 receptor agonists on non-alcoholic fatty liver disease and inflammation," World Journal of Gastroenterology, vol. 20, no. 40, pp. 14821-14830, 2014.
-
(2014)
World Journal of Gastroenterology
, vol.20
, Issue.40
, pp. 14821-14830
-
-
Wang, X.-C.1
Gusdon, A.M.2
Liu, H.3
Qu, S.4
-
22
-
-
48949088649
-
Anti-proliferative effect of pro-inflammatory cytokines in cultured β cells is associated with extracellular signal-regulated kinase 1/2 pathway inhibition: Protective role of glucagon-like peptide -1
-
M. Blandino-Rosano, G. Perez-Arana, J. M. Mellado-Gil, C. Segundo, and M. Aguilar-Diosdado, "Anti-proliferative effect of pro-inflammatory cytokines in cultured β cells is associated with extracellular signal-regulated kinase 1/2 pathway inhibition: protective role of glucagon-like peptide -1," Journal of Molecular Endocrinology, vol. 41, no. 1-2, pp. 35-44, 2008.
-
(2008)
Journal of Molecular Endocrinology
, vol.41
, Issue.1-2
, pp. 35-44
-
-
Blandino-Rosano, M.1
Perez-Arana, G.2
Mellado-Gil, J.M.3
Segundo, C.4
Aguilar-Diosdado, M.5
-
23
-
-
67650057935
-
A long-acting glucagon-like peptide-1 analogue attenuates induction of plasminogen activator inhibitor type-1 and vascular adhesion molecules
-
H. Liu, A. E. Dear, L. B. Knudsen, and R. W. Simpson, "A long-acting glucagon-like peptide-1 analogue attenuates induction of plasminogen activator inhibitor type-1 and vascular adhesion molecules," The Journal of Endocrinology, vol. 201, no. 1, pp. 59-66, 2009.
-
(2009)
The Journal of Endocrinology
, vol.201
, Issue.1
, pp. 59-66
-
-
Liu, H.1
Dear, A.E.2
Knudsen, L.B.3
Simpson, R.W.4
-
24
-
-
84874085243
-
The type 2 diabetes drug liraglutide reduces chronic inflammation induced by irradiation in the mouse brain
-
V. Parthsarathy and C. Hölscher, "The type 2 diabetes drug liraglutide reduces chronic inflammation induced by irradiation in the mouse brain," European Journal of Pharmacology, vol. 700, no. 1-3, pp. 42-50, 2013.
-
(2013)
European Journal of Pharmacology
, vol.700
, Issue.1-3
, pp. 42-50
-
-
Parthsarathy, V.1
Hölscher, C.2
-
25
-
-
84899895454
-
Sitagliptin prevents inflammation and apoptotic cell death in the kidney of type 2 diabetic animals
-
C. Marques, C. Mega, A. Gonçalves et al., "Sitagliptin prevents inflammation and apoptotic cell death in the kidney of type 2 diabetic animals," Mediators of Inflammation, vol. 2014, Article ID 538737, 15 pages, 2014.
-
(2014)
Mediators of Inflammation
, vol.2014
-
-
Marques, C.1
Mega, C.2
Gonçalves, A.3
-
26
-
-
84866356839
-
-/- mice
-
-/- mice," Diabetologia, vol. 55, no. 8, pp. 2267-2275, 2012.
-
(2012)
Diabetologia
, vol.55
, Issue.8
, pp. 2267-2275
-
-
Vittone, F.1
Liberman, A.2
Vasic, D.3
-
27
-
-
0034904508
-
The role of glial cells in Parkinson's disease
-
M. Vila, V. Jackson-Lewis, C. Guégan et al., "The role of glial cells in Parkinson's disease," Current Opinion in Neurology, vol. 14, no. 4, pp. 483-489, 2001.
-
(2001)
Current Opinion in Neurology
, vol.14
, Issue.4
, pp. 483-489
-
-
Vila, M.1
Jackson-Lewis, V.2
Guégan, C.3
-
28
-
-
84964374284
-
Glucagon-like peptide-1 preserves non-alcoholic fatty liver disease through inhibition of the endoplasmic reticulum stress-associated pathway
-
N. Ao, J. Yang, X. Wang, and J. Du, "Glucagon-like peptide-1 preserves non-alcoholic fatty liver disease through inhibition of the endoplasmic reticulum stress-associated pathway," Hepatology Research, 2015.
-
(2015)
Hepatology Research
-
-
Ao, N.1
Yang, J.2
Wang, X.3
Du, J.4
-
29
-
-
79961180020
-
Mechanisms mediating the diuretic and natriuretic actions of the incretin hormone glucagon-like peptide-1
-
R. O. Crajoinas, F. T. Oricchio, T. D. Pessoa et al., "Mechanisms mediating the diuretic and natriuretic actions of the incretin hormone glucagon-like peptide-1," The American Journal of Physiology-Renal Physiology, vol. 301, no. 2, pp. F355-F363, 2011.
-
(2011)
The American Journal of Physiology-Renal Physiology
, vol.301
, Issue.2
, pp. F355-F363
-
-
Crajoinas, R.O.1
Oricchio, F.T.2
Pessoa, T.D.3
-
30
-
-
84929306694
-
Glucagon like peptide-1 attenuates bleomycin-induced pulmonary fibrosis, involving the inactivation of NF-κB in mice
-
S. Gou, T. Zhu, W. Wang, M. Xiao, X.-C. Wang, and Z.-H. Chen, "Glucagon like peptide-1 attenuates bleomycin-induced pulmonary fibrosis, involving the inactivation of NF-κB in mice," International Immunopharmacology, vol. 22, no. 2, pp. 498-504, 2014.
-
(2014)
International Immunopharmacology
, vol.22
, Issue.2
, pp. 498-504
-
-
Gou, S.1
Zhu, T.2
Wang, W.3
Xiao, M.4
Wang, X.-C.5
Chen, Z.-H.6
-
31
-
-
80054681735
-
Glucagon-like peptide-1 (GLP-1) and the regulation of human invariant natural killer T cells: Lessons from obesity, diabetes and psoriasis
-
A. E. Hogan, A. M. Tobin, T. Ahern et al., "Glucagon-like peptide-1 (GLP-1) and the regulation of human invariant natural killer T cells: lessons from obesity, diabetes and psoriasis," Diabetologia, vol. 54, no. 11, pp. 2745-2754, 2011.
-
(2011)
Diabetologia
, vol.54
, Issue.11
, pp. 2745-2754
-
-
Hogan, A.E.1
Tobin, A.M.2
Ahern, T.3
-
32
-
-
84886451568
-
Exendin-4 and GLP-1 decreases induced expression of ICAM-1, VCAM-1 and RAGE in human retinal pigment epithelial cells
-
M. Dorecka, K. Siemianowicz, T. Francuz et al., "Exendin-4 and GLP-1 decreases induced expression of ICAM-1, VCAM-1 and RAGE in human retinal pigment epithelial cells," Pharmacological Reports, vol. 65, no. 4, pp. 884-890, 2013.
-
(2013)
Pharmacological Reports
, vol.65
, Issue.4
, pp. 884-890
-
-
Dorecka, M.1
Siemianowicz, K.2
Francuz, T.3
-
33
-
-
28044432292
-
Autoimmune destruction of pancreatic β cells
-
J.-W. Yoon and H.-S. Jun, "Autoimmune destruction of pancreatic β cells," American Journal of Therapeutics, vol. 12, no. 6, pp. 580-591, 2005.
-
(2005)
American Journal of Therapeutics
, vol.12
, Issue.6
, pp. 580-591
-
-
Yoon, J.-W.1
Jun, H.-S.2
-
34
-
-
0027953703
-
Banting lecture: Insulin action, diabetogenes, and the cause of type II diabetes
-
C. R. Kahn, "Banting lecture: insulin action, diabetogenes, and the cause of type II diabetes," Diabetes, vol. 43, no. 8, pp. 1066-1084, 1994.
-
(1994)
Diabetes
, vol.43
, Issue.8
, pp. 1066-1084
-
-
Kahn, C.R.1
-
35
-
-
0024160877
-
Banting lecture 1988. Role of insulin resistance in human disease
-
G. M. Reaven, "Banting lecture 1988. Role of insulin resistance in human disease," Diabetes, vol. 37, no. 12, pp. 1595-1607, 1988.
-
(1988)
Diabetes
, vol.37
, Issue.12
, pp. 1595-1607
-
-
Reaven, G.M.1
-
36
-
-
0028229508
-
Insulin resistance or insulin deficiency. Which is the primary cause of NIDDM?
-
S. I. Taylor, D. Accili, and Y. Imai, "Insulin resistance or insulin deficiency. Which is the primary cause of NIDDM?" Diabetes, vol. 43, no. 6, pp. 735-740, 1994.
-
(1994)
Diabetes
, vol.43
, Issue.6
, pp. 735-740
-
-
Taylor, S.I.1
Accili, D.2
Imai, Y.3
-
37
-
-
84885063145
-
Diabetes and beta cell function: From mechanisms to evaluation and clinical implications
-
S. Cernea and M. Dobreanu, "Diabetes and beta cell function: from mechanisms to evaluation and clinical implications," Biochemia Medica, vol. 23, no. 3, pp. 266-280, 2013.
-
(2013)
Biochemia Medica
, vol.23
, Issue.3
, pp. 266-280
-
-
Cernea, S.1
Dobreanu, M.2
-
38
-
-
84901445280
-
β-Cell failure in type 2 diabetes: Postulated mechanisms and prospects for prevention and treatment
-
P. A. Halban, K. S. Polonsky, D. W. Bowden et al., "β-Cell failure in type 2 diabetes: postulated mechanisms and prospects for prevention and treatment," Diabetes Care, vol. 37, no. 6, pp. 1751-1758, 2014.
-
(2014)
Diabetes Care
, vol.37
, Issue.6
, pp. 1751-1758
-
-
Halban, P.A.1
Polonsky, K.S.2
Bowden, D.W.3
-
39
-
-
33644749322
-
Mechanisms of pancreatic β-cell death in type 1 and type 2 diabetes: Many differences, few similarities
-
M. Cnop, N. Welsh, J.-C. Jonas, A. Jörns, S. Lenzen, and D. L. Eizirik, "Mechanisms of pancreatic β-cell death in type 1 and type 2 diabetes: many differences, few similarities," Diabetes, vol. 54, supplement 2, pp. S97-S107, 2005.
-
(2005)
Diabetes
, vol.54
, pp. S97-S107
-
-
Cnop, M.1
Welsh, N.2
Jonas, J.-C.3
Jörns, A.4
Lenzen, S.5
Eizirik, D.L.6
-
40
-
-
0023784346
-
IFN-γ and tumor necrosis factor-α: Cytotoxicity to murine islets of Langerhans
-
I. L. Campbell, A. Iscaro, and L. C. Harrison, "IFN-γ and tumor necrosis factor-α: cytotoxicity to murine islets of Langerhans," Journal of Immunology, vol. 141, no. 7, pp. 2325-2329, 1988.
-
(1988)
Journal of Immunology
, vol.141
, Issue.7
, pp. 2325-2329
-
-
Campbell, I.L.1
Iscaro, A.2
Harrison, L.C.3
-
41
-
-
0033557102
-
Inhibitory effects of streptozotocin, tumor necrosis factor-α, and interleukin-1β on glucokinase activity in pancreatic islets and gene expression of GLUT2 and glucokinase
-
C. Park, J.-R. Kim, J.-K. Shim et al., "Inhibitory effects of streptozotocin, tumor necrosis factor-α, and interleukin-1β on glucokinase activity in pancreatic islets and gene expression of GLUT2 and glucokinase," Archives of Biochemistry and Biophysics, vol. 362, no. 2, pp. 217-224, 1999.
-
(1999)
Archives of Biochemistry and Biophysics
, vol.362
, Issue.2
, pp. 217-224
-
-
Park, C.1
Kim, J.-R.2
Shim, J.-K.3
-
42
-
-
33644747390
-
Mechanisms of β-cell death in type 2 diabetes
-
M. Y. Donath, J. A. Ehses, K. Maedler et al., "Mechanisms of β-cell death in type 2 diabetes," Diabetes, vol. 54, supplement 2, pp. S108-S113, 2005.
-
(2005)
Diabetes
, vol.54
, pp. S108-S113
-
-
Donath, M.Y.1
Ehses, J.A.2
Maedler, K.3
-
43
-
-
84930330603
-
Endogenous GLP-1 as a key self-defense molecule against lipotoxicity in pancreatic islets
-
C. Huang, L. Yuan, and S. Cao, "Endogenous GLP-1 as a key self-defense molecule against lipotoxicity in pancreatic islets," International Journal of Molecular Medicine, vol. 36, no. 1, pp. 173-185, 2015.
-
(2015)
International Journal of Molecular Medicine
, vol.36
, Issue.1
, pp. 173-185
-
-
Huang, C.1
Yuan, L.2
Cao, S.3
-
44
-
-
84857422732
-
Antiapoptotic actions of exendin-4 against hypoxia and cytokines are augmented by CREB
-
K. Velmurugan, A. N. Balamurugan, G. Loganathan, A. Ahmad, B. J. Hering, and S. Pugazhenthi, "Antiapoptotic actions of exendin-4 against hypoxia and cytokines are augmented by CREB," Endocrinology, vol. 153, no. 3, pp. 1116-1128, 2012.
-
(2012)
Endocrinology
, vol.153
, Issue.3
, pp. 1116-1128
-
-
Velmurugan, K.1
Balamurugan, A.N.2
Loganathan, G.3
Ahmad, A.4
Hering, B.J.5
Pugazhenthi, S.6
-
45
-
-
77954611378
-
Reversal of new-onset diabetes through modulating inflammation and stimulating β-cell replication in nonobese diabetic mice by a dipeptidyl peptidase IV inhibitor
-
L. Tian, J. Gao, J. Hao et al., "Reversal of new-onset diabetes through modulating inflammation and stimulating β-cell replication in nonobese diabetic mice by a dipeptidyl peptidase IV inhibitor," Endocrinology, vol. 151, no. 7, pp. 3049-3060, 2010.
-
(2010)
Endocrinology
, vol.151
, Issue.7
, pp. 3049-3060
-
-
Tian, L.1
Gao, J.2
Hao, J.3
-
46
-
-
84865459917
-
Chronic DPP-IV inhibition with PKF-275-055 attenuates inflammation and improves gene expressions responsible for insulin secretion in streptozotocin induced diabetic rats
-
A. S. Akarte, B. P. Srinivasan, S. Gandhi, and S. Sole, "Chronic DPP-IV inhibition with PKF-275-055 attenuates inflammation and improves gene expressions responsible for insulin secretion in streptozotocin induced diabetic rats," European Journal of Pharmaceutical Sciences, vol. 47, no. 2, pp. 456-463, 2012.
-
(2012)
European Journal of Pharmaceutical Sciences
, vol.47
, Issue.2
, pp. 456-463
-
-
Akarte, A.S.1
Srinivasan, B.P.2
Gandhi, S.3
Sole, S.4
-
47
-
-
84919620889
-
DPP IV inhibitor suppresses STZ-induced islets injury dependent on activation of the IGFR/Akt/mTOR signaling pathways by GLP-1 in monkeys
-
Y. Zhang, Y. Chen, J. Cheng, Z. Guo, Y. Lu, and B. Tian, "DPP IV inhibitor suppresses STZ-induced islets injury dependent on activation of the IGFR/Akt/mTOR signaling pathways by GLP-1 in monkeys," Biochemical and Biophysical Research Communications, vol. 456, no. 1, pp. 139-144, 2015.
-
(2015)
Biochemical and Biophysical Research Communications
, vol.456
, Issue.1
, pp. 139-144
-
-
Zhang, Y.1
Chen, Y.2
Cheng, J.3
Guo, Z.4
Lu, Y.5
Tian, B.6
-
48
-
-
77957678974
-
Anti-inflammatory action of exendin-4 in human islets is enhanced by phosphodiesterase inhibitors: Potential therapeutic benefits in diabetic patients
-
U. Pugazhenthi, K. Velmurugan, A. Tran, G. Mahaffey, and S. Pugazhenthi, "Anti-inflammatory action of exendin-4 in human islets is enhanced by phosphodiesterase inhibitors: potential therapeutic benefits in diabetic patients," Diabetologia, vol. 53, no. 11, pp. 2357-2368, 2010.
-
(2010)
Diabetologia
, vol.53
, Issue.11
, pp. 2357-2368
-
-
Pugazhenthi, U.1
Velmurugan, K.2
Tran, A.3
Mahaffey, G.4
Pugazhenthi, S.5
-
49
-
-
84930476726
-
Anti-inflammatory properties of exenatide in human pancreatic islets
-
S. R. Cechin, I. Pérez-Álvarez, E. Fenjves et al., "Anti-inflammatory properties of exenatide in human pancreatic islets," Cell Transplantation, vol. 21, no. 4, pp. 633-648, 2012.
-
(2012)
Cell Transplantation
, vol.21
, Issue.4
, pp. 633-648
-
-
Cechin, S.R.1
Pérez-Álvarez, I.2
Fenjves, E.3
-
50
-
-
33745216724
-
MCP-1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesity
-
H. Kanda, S. Tateya, Y. Tamori et al., "MCP-1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesity,"The Journal of Clinical Investigation, vol. 116, no. 6, pp. 1494-1505, 2006.
-
(2006)
The Journal of Clinical Investigation
, vol.116
, Issue.6
, pp. 1494-1505
-
-
Kanda, H.1
Tateya, S.2
Tamori, Y.3
-
51
-
-
31044456529
-
CCR2 modulates inflammatory and metabolic effects of high-fat feeding
-
S. P. Weisberg, D. Hunter, R. Huber et al., "CCR2 modulates inflammatory and metabolic effects of high-fat feeding," Journal of Clinical Investigation, vol. 116, no. 1, pp. 115-124, 2006.
-
(2006)
Journal of Clinical Investigation
, vol.116
, Issue.1
, pp. 115-124
-
-
Weisberg, S.P.1
Hunter, D.2
Huber, R.3
-
52
-
-
68349137821
-
Normalization of obesity-associated insulin resistance through immunotherapy
-
S. Winer, Y. Chan, G. Paltser et al., "Normalization of obesity-associated insulin resistance through immunotherapy," Nature Medicine, vol. 15, no. 8, pp. 921-929, 2009.
-
(2009)
Nature Medicine
, vol.15
, Issue.8
, pp. 921-929
-
-
Winer, S.1
Chan, Y.2
Paltser, G.3
-
53
-
-
84944035499
-
Is there a link between liraglutide and pancreatitis? A post hoc review of pooled and patient-level data from completed liraglutide type 2 diabetes clinical trials
-
T. M. Jensen, K. Saha, and W. M. Steinberg, "Is there a link between liraglutide and pancreatitis? A post hoc review of pooled and patient-level data from completed liraglutide type 2 diabetes clinical trials," Diabetes Care, vol. 38, pp. 1058-1066, 2015.
-
(2015)
Diabetes Care
, vol.38
, pp. 1058-1066
-
-
Jensen, T.M.1
Saha, K.2
Steinberg, W.M.3
-
54
-
-
84869217643
-
Pancreatitis: A potential complication of liraglutide?
-
A. S. Franks, P. H. Lee, and C. M. George, "Pancreatitis: a potential complication of liraglutide?" Annals of Pharmacotherapy, vol. 46, no. 11, pp. 1547-1553, 2012.
-
(2012)
Annals of Pharmacotherapy
, vol.46
, Issue.11
, pp. 1547-1553
-
-
Franks, A.S.1
Lee, P.H.2
George, C.M.3
-
55
-
-
84878185729
-
A critical analysis of the clinical use of incretin-based therapies: Are the GLP-1 therapies safe?
-
P. C. Butler, M. Elashoff, R. Elashoff, and E. A. M. Gale, "A critical analysis of the clinical use of incretin-based therapies: are the GLP-1 therapies safe?" Diabetes Care, vol. 36, no. 7, pp. 2118-2125, 2013.
-
(2013)
Diabetes Care
, vol.36
, Issue.7
, pp. 2118-2125
-
-
Butler, P.C.1
Elashoff, M.2
Elashoff, R.3
Gale, E.A.M.4
-
56
-
-
34249277445
-
Endotoxemia, immune response to periodontal pathogens, and systemic inflammation associate with incident cardiovascular disease events
-
P. J. Pussinen, K. Tuomisto, P. Jousilahti, A. S. Havulinna, J. Sundvall, and V. Salomaa, "Endotoxemia, immune response to periodontal pathogens, and systemic inflammation associate with incident cardiovascular disease events," Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 27, no. 6, pp. 1433-1439, 2007.
-
(2007)
Arteriosclerosis, Thrombosis, and Vascular Biology
, vol.27
, Issue.6
, pp. 1433-1439
-
-
Pussinen, P.J.1
Tuomisto, K.2
Jousilahti, P.3
Havulinna, A.S.4
Sundvall, J.5
Salomaa, V.6
-
57
-
-
84859307224
-
Of microbes and meals: The health consequences of dietary endotoxemia
-
C. J. Kelly, S. P. Colgan, and D. N. Frank, "Of microbes and meals: the health consequences of dietary endotoxemia," Nutrition in Clinical Practice, vol. 27, no. 2, pp. 215-225, 2012.
-
(2012)
Nutrition in Clinical Practice
, vol.27
, Issue.2
, pp. 215-225
-
-
Kelly, C.J.1
Colgan, S.P.2
Frank, D.N.3
-
58
-
-
84876808529
-
Immunity, atherosclerosis and cardiovascular disease
-
J. Frostegård, "Immunity, atherosclerosis and cardiovascular disease," BMC Medicine, vol. 11, article 117, 2013.
-
(2013)
BMC Medicine
, vol.11
-
-
Frostegård, J.1
-
59
-
-
67849084815
-
Glucagon-like peptide-1 protects mesenteric endothelium from injury during inflammation
-
K. C. Dozier, E. L. Cureton, R. O. Kwan, B. Curran, J. Sadjadi, and G. P. Victorino, "Glucagon-like peptide-1 protects mesenteric endothelium from injury during inflammation," Peptides, vol. 30, no. 9, pp. 1735-1741, 2009.
-
(2009)
Peptides
, vol.30
, Issue.9
, pp. 1735-1741
-
-
Dozier, K.C.1
Cureton, E.L.2
Kwan, R.O.3
Curran, B.4
Sadjadi, J.5
Victorino, G.P.6
-
60
-
-
84901341959
-
Glucagon-Like Peptide-1 (GLP-1) analog liraglutide inhibits endothelial cell inflammation through a calcium and AMPK dependent mechanism
-
N. M. Krasner, Y. Ido, N. B. Ruderman, and J. M. Cacicedo, "Glucagon-Like Peptide-1 (GLP-1) analog liraglutide inhibits endothelial cell inflammation through a calcium and AMPK dependent mechanism," PLoS ONE, vol. 9, no. 5, Article ID e97554, 2014.
-
(2014)
PLoS ONE
, vol.9
, Issue.5
-
-
Krasner, N.M.1
Ido, Y.2
Ruderman, N.B.3
Cacicedo, J.M.4
-
61
-
-
77958052010
-
A glucagon-like peptide-1 (GLP-1) analogue, liraglutide, upregulates nitric oxide production and exerts anti-inflammatory action in endothelial cells
-
Y. Hattori, T. Jojima, A. Tomizawa et al., "A glucagon-like peptide-1 (GLP-1) analogue, liraglutide, upregulates nitric oxide production and exerts anti-inflammatory action in endothelial cells," Diabetologia, vol. 53, no. 10, pp. 2256-2263, 2010.
-
(2010)
Diabetologia
, vol.53
, Issue.10
, pp. 2256-2263
-
-
Hattori, Y.1
Jojima, T.2
Tomizawa, A.3
-
62
-
-
84858707110
-
The glucagon-like peptide 1 analog liraglutide reduces TNF-α-induced oxidative stress and inflammation in endothelial cells
-
A. Shiraki, J.-I. Oyama, H. Komoda et al., "The glucagon-like peptide 1 analog liraglutide reduces TNF-α-induced oxidative stress and inflammation in endothelial cells," Atherosclerosis, vol. 221, no. 2, pp. 375-382, 2012.
-
(2012)
Atherosclerosis
, vol.221
, Issue.2
, pp. 375-382
-
-
Shiraki, A.1
Oyama, J.-I.2
Komoda, H.3
-
63
-
-
84892402412
-
Exendin-4 decreases liver inflammation and atherosclerosis development simultaneously by reducing macrophage infiltration
-
Y. Wang, E. T. Parlevliet, J. J. Geerling et al., "Exendin-4 decreases liver inflammation and atherosclerosis development simultaneously by reducing macrophage infiltration," British Journal of Pharmacology, vol. 171, no. 3, pp. 723-734, 2014.
-
(2014)
British Journal of Pharmacology
, vol.171
, Issue.3
, pp. 723-734
-
-
Wang, Y.1
Parlevliet, E.T.2
Geerling, J.J.3
-
64
-
-
84919712450
-
DPP-4 inhibitors repress NLRP3 inflammasome and interleukin-1beta via GLP-1 receptor in macrophages through protein kinase C pathway
-
Y. Dai, D. Dai, X. Wang, Z. Ding, and J. L. Mehta, "DPP-4 inhibitors repress NLRP3 inflammasome and interleukin-1beta via GLP-1 receptor in macrophages through protein kinase C pathway," Cardiovascular Drugs and Therapy, vol. 28, no. 5, pp. 425-432, 2014.
-
(2014)
Cardiovascular Drugs and Therapy
, vol.28
, Issue.5
, pp. 425-432
-
-
Dai, Y.1
Dai, D.2
Wang, X.3
Ding, Z.4
Mehta, J.L.5
-
65
-
-
84959161493
-
Dipeptidyl peptidase-4 inhibitor, linagliptin, ameliorates endothelial dysfunction and atherogenesis in normoglycemic apolipoprotein-E deficient mice
-
H. M. Salim, D. Fukuda, Y. Higashikuni et al., "Dipeptidyl peptidase-4 inhibitor, linagliptin, ameliorates endothelial dysfunction and atherogenesis in normoglycemic apolipoprotein-E deficient mice," Vascular Pharmacology, vol. 79, pp. 16-23, 2015.
-
(2015)
Vascular Pharmacology
, vol.79
, pp. 16-23
-
-
Salim, H.M.1
Fukuda, D.2
Higashikuni, Y.3
-
66
-
-
84893162958
-
The DPP-4 inhibitor sitagliptin attenuates the progress of atherosclerosis in apolipoprotein-E-knockout mice via AMPK- and MAPK-dependent mechanisms
-
Y. Zeng, C. Li, M. Guan et al., "The DPP-4 inhibitor sitagliptin attenuates the progress of atherosclerosis in apolipoprotein-E-knockout mice via AMPK- and MAPK-dependent mechanisms," Cardiovascular Diabetology, vol. 13, article 32, 2014.
-
(2014)
Cardiovascular Diabetology
, vol.13
-
-
Zeng, Y.1
Li, C.2
Guan, M.3
-
67
-
-
84954308309
-
Effects of glucagon-like peptide-1 on advanced glycation endproduct-induced aortic endothelial dysfunction in streptozotocin-induced diabetic rats: Possible roles of Rho kinase- and AMP kinase-mediated nuclear factor κB signaling pathways
-
S. Tang, Q. Zhang, H. Tang et al., "Effects of glucagon-like peptide-1 on advanced glycation endproduct-induced aortic endothelial dysfunction in streptozotocin-induced diabetic rats: possible roles of Rho kinase- and AMP kinase-mediated nuclear factor κB signaling pathways," Endocrine, pp. 1-10, 2016.
-
(2016)
Endocrine
, pp. 1-10
-
-
Tang, S.1
Zhang, Q.2
Tang, H.3
-
68
-
-
84862908699
-
A dipeptidyl peptidase-4 inhibitor, des-fluoro-sitagliptin, improves endothelial function and reduces atherosclerotic lesion formation in apolipoprotein E-deficient mice
-
J. Matsubara, S. Sugiyama, K. Sugamura et al., "A dipeptidyl peptidase-4 inhibitor, des-fluoro-sitagliptin, improves endothelial function and reduces atherosclerotic lesion formation in apolipoprotein E-deficient mice," Journal of the American College of Cardiology, vol. 59, no. 3, pp. 265-276, 2012.
-
(2012)
Journal of the American College of Cardiology
, vol.59
, Issue.3
, pp. 265-276
-
-
Matsubara, J.1
Sugiyama, S.2
Sugamura, K.3
-
69
-
-
85013728733
-
Dipeptidylpeptidase-4 inhibitor, alogliptin, attenuates arterial inflammation and neointimal formation after injury in low-density lipoprotein (LDL) receptor-deficient mice
-
K. Akita, K. Isoda, K. Shimada, and H. Daida, "Dipeptidylpeptidase-4 inhibitor, alogliptin, attenuates arterial inflammation and neointimal formation after injury in low-density lipoprotein (LDL) receptor-deficient mice," Journal of the American Heart Association, vol. 4, no. 3, Article ID e001469, 2015.
-
(2015)
Journal of the American Heart Association
, vol.4
, Issue.3
-
-
Akita, K.1
Isoda, K.2
Shimada, K.3
Daida, H.4
-
70
-
-
84888120953
-
-/- mice
-
-/- mice," Atherosclerosis, vol. 231, no. 2, pp. 427-435, 2013.
-
(2013)
Atherosclerosis
, vol.231
, Issue.2
, pp. 427-435
-
-
Burgmaier, M.1
Liberman, A.2
Möllmann, J.3
-
71
-
-
84870203841
-
Anti-inflammatory properties of sirtuin 6 in human umbilical vein endothelial cells
-
M. Lappas, "Anti-inflammatory properties of sirtuin 6 in human umbilical vein endothelial cells,"Mediators of Inflammation, vol. 2012,Article ID597514, 11 pages, 2012.
-
(2012)
Mediators of Inflammation
, vol.2012
-
-
Lappas, M.1
-
72
-
-
84902375846
-
Anti-inflammatory effect of exendin-4 postconditioning during myocardial ischemia and reperfusion
-
X. Du, X. Hu, and J. Wei, "Anti-inflammatory effect of exendin-4 postconditioning during myocardial ischemia and reperfusion," Molecular Biology Reports, vol. 41, no. 6, pp. 3853-3857, 2014.
-
(2014)
Molecular Biology Reports
, vol.41
, Issue.6
, pp. 3853-3857
-
-
Du, X.1
Hu, X.2
Wei, J.3
-
73
-
-
85027916650
-
Glucagon-like peptide-1 receptor agonist protects against hyperglycemia-induced cardiocytes injury by inhibiting high mobility group box 1 expression
-
Y. Cai, X. Hu, B. Yi, T. Zhang, and Z. Wen, "Glucagon-like peptide-1 receptor agonist protects against hyperglycemia-induced cardiocytes injury by inhibiting high mobility group box 1 expression," Molecular Biology Reports, vol. 39, no. 12, pp. 10705-10711, 2012.
-
(2012)
Molecular Biology Reports
, vol.39
, Issue.12
, pp. 10705-10711
-
-
Cai, Y.1
Hu, X.2
Yi, B.3
Zhang, T.4
Wen, Z.5
-
74
-
-
84936876236
-
Sitagliptin alleviated myocardial remodeling of the left ventricle and improved cardiac diastolic dysfunction in diabetic rats
-
Y.-S. Liu, Z.-W. Huang, L. Wang et al., "Sitagliptin alleviated myocardial remodeling of the left ventricle and improved cardiac diastolic dysfunction in diabetic rats," Journal of Pharmacological Sciences, vol. 127, no. 3, pp. 260-274, 2015.
-
(2015)
Journal of Pharmacological Sciences
, vol.127
, Issue.3
, pp. 260-274
-
-
Liu, Y.-S.1
Huang, Z.-W.2
Wang, L.3
-
75
-
-
24144453087
-
Microglia and inflammation-mediated neurodegeneration: Multiple triggers with a common mechanism
-
M. L. Block and J.-S. Hong, "Microglia and inflammation-mediated neurodegeneration: multiple triggers with a common mechanism," Progress in Neurobiology, vol. 76, no. 2, pp. 77-98, 2005.
-
(2005)
Progress in Neurobiology
, vol.76
, Issue.2
, pp. 77-98
-
-
Block, M.L.1
Hong, J.-S.2
-
76
-
-
34548822734
-
The role of anti-inflammatory agents in Parkinson's disease
-
E. G. McGeer and P. L. McGeer, "The role of anti-inflammatory agents in Parkinson's disease," CNS Drugs, vol. 21, no. 10, pp. 789-797, 2007.
-
(2007)
CNS Drugs
, vol.21
, Issue.10
, pp. 789-797
-
-
McGeer, E.G.1
McGeer, P.L.2
-
77
-
-
11444256801
-
Glia and their cytokines in progression of neurodegeneration
-
R. E. Mrak and W. S. T. Griffin, "Glia and their cytokines in progression of neurodegeneration," Neurobiology of Aging, vol. 26, no. 3, pp. 349-354, 2005.
-
(2005)
Neurobiology of Aging
, vol.26
, Issue.3
, pp. 349-354
-
-
Mrak, R.E.1
Griffin, W.S.T.2
-
78
-
-
78650029989
-
Insulin metabolism and the risk of Alzheimer disease: The Rotterdam Study
-
E. M. C. Schrijvers, J. C. M. Witteman, E. J. G. Sijbrands, A. Hofman, P. J. Koudstaal, and M. M. B. Breteler, "Insulin metabolism and the risk of Alzheimer disease: the Rotterdam Study," Neurology, vol. 75, no. 22, pp. 1982-1987, 2010.
-
(2010)
Neurology
, vol.75
, Issue.22
, pp. 1982-1987
-
-
Schrijvers, E.M.C.1
Witteman, J.C.M.2
Sijbrands, E.J.G.3
Hofman, A.4
Koudstaal, P.J.5
Breteler, M.M.B.6
-
79
-
-
84872569583
-
GLP-1 secretion by microglial cells and decreased CNS expression in obesity
-
C. Kappe, L. M. Tracy, C. Patrone, K. Iverfeldt, and Å. Sjöholm, "GLP-1 secretion by microglial cells and decreased CNS expression in obesity," Journal of Neuroinflammation, vol. 9, article 276, 2012.
-
(2012)
Journal of Neuroinflammation
, vol.9
-
-
Kappe, C.1
Tracy, L.M.2
Patrone, C.3
Iverfeldt, K.4
Sjöholm, Å.5
-
80
-
-
22144491473
-
Enhancing central nervous system endogenous GLP-1 receptor pathways for intervention in Alzheimer's disease
-
T. Perry and N. H. Greig, "Enhancing central nervous system endogenous GLP-1 receptor pathways for intervention in Alzheimer's disease," Current Alzheimer Research, vol. 2, no. 3, pp. 377-385, 2005.
-
(2005)
Current Alzheimer Research
, vol.2
, Issue.3
, pp. 377-385
-
-
Perry, T.1
Greig, N.H.2
-
81
-
-
77953880083
-
Incretin analogues that have been developed to treat type 2 diabetes hold promise as a novel treatment strategy for Alzheimer's disease
-
C. Holscher, "Incretin analogues that have been developed to treat type 2 diabetes hold promise as a novel treatment strategy for Alzheimer's disease," Recent Patents on CNS Drug Discovery, vol. 5, no. 2, pp. 109-117, 2010.
-
(2010)
Recent Patents on CNS Drug Discovery
, vol.5
, Issue.2
, pp. 109-117
-
-
Holscher, C.1
-
82
-
-
76449115696
-
Glucagon-like peptide 1 receptor stimulation as a means of neuroprotection
-
A. Harkavyi and P. S. Whitton, "Glucagon-like peptide 1 receptor stimulation as a means of neuroprotection," British Journal of Pharmacology, vol. 159, no. 3, pp. 495-501, 2010.
-
(2010)
British Journal of Pharmacology
, vol.159
, Issue.3
, pp. 495-501
-
-
Harkavyi, A.1
Whitton, P.S.2
-
83
-
-
69549128161
-
Receptors for the incretin glucagon-like peptide-1 are expressed on neurons in the central nervous system
-
A. Hamilton and C. Hölscher, "Receptors for the incretin glucagon-like peptide-1 are expressed on neurons in the central nervous system," NeuroReport, vol. 20, no. 13, pp. 1161-1166, 2009.
-
(2009)
NeuroReport
, vol.20
, Issue.13
, pp. 1161-1166
-
-
Hamilton, A.1
Hölscher, C.2
-
84
-
-
79751479118
-
Novel GLP-1 mimetics developed to treat type 2 diabetes promote progenitor cell proliferation in the brain
-
A. Hamilton, S. Patterson, D. Porter, V. A. Gault, and C. Holscher, "Novel GLP-1 mimetics developed to treat type 2 diabetes promote progenitor cell proliferation in the brain," Journal of Neuroscience Research, vol. 89, no. 4, pp. 481-489, 2011.
-
(2011)
Journal of Neuroscience Research
, vol.89
, Issue.4
, pp. 481-489
-
-
Hamilton, A.1
Patterson, S.2
Porter, D.3
Gault, V.A.4
Holscher, C.5
-
85
-
-
84858713174
-
Drugs developed to treat diabetes, liraglutide and lixisenatide, cross the blood brain barrier and enhance neurogenesis
-
K. Hunter and C. Hölscher, "Drugs developed to treat diabetes, liraglutide and lixisenatide, cross the blood brain barrier and enhance neurogenesis," BMC Neuroscience, vol. 13, article 33, 2012.
-
(2012)
BMC Neuroscience
, vol.13
-
-
Hunter, K.1
Hölscher, C.2
-
86
-
-
79955749452
-
The diabetes drug liraglutide prevents degenerative processes in a mouse model of Alzheimer's disease
-
P. L. Mcclean, V. Parthsarathy, E. Faivre, and C. Holscher, "The diabetes drug liraglutide prevents degenerative processes in a mouse model of Alzheimer's disease," The Journal of Neuroscience, vol. 31, no. 17, pp. 6587-6594, 2011.
-
(2011)
The Journal of Neuroscience
, vol.31
, Issue.17
, pp. 6587-6594
-
-
Mcclean, P.L.1
Parthsarathy, V.2
Faivre, E.3
Holscher, C.4
-
87
-
-
84899478592
-
Activation of spinal glucagon-like peptide-1 receptors specifically suppresses pain hypersensitivity
-
N. Gong, Q. Xiao, B. Zhu et al., "Activation of spinal glucagon-like peptide-1 receptors specifically suppresses pain hypersensitivity," Journal of Neuroscience, vol. 34, no. 15, pp. 5322-5334, 2014.
-
(2014)
Journal of Neuroscience
, vol.34
, Issue.15
, pp. 5322-5334
-
-
Gong, N.1
Xiao, Q.2
Zhu, B.3
-
88
-
-
0027304893
-
Action of the diabetogenic drug streptozotocin on glycolytic and glycogenolytic metabolism in adult rat brain cortex and hippocampus
-
K. Plaschke and S. Hoyer, "Action of the diabetogenic drug streptozotocin on glycolytic and glycogenolytic metabolism in adult rat brain cortex and hippocampus," International Journal of Developmental Neuroscience, vol. 11, no. 4, pp. 477-483, 1993.
-
(1993)
International Journal of Developmental Neuroscience
, vol.11
, Issue.4
, pp. 477-483
-
-
Plaschke, K.1
Hoyer, S.2
-
89
-
-
84942435321
-
Exenatide reduces TNF-α expression and improves hippocampal neuron numbers and memory in streptozotocin treated rats
-
V. Solmaz, B. P. C¸inar, G. Yiǧittürk, T. C¸avus¸oǧlu, D. Tas¸kiran, and O. Erbas¸, "Exenatide reduces TNF-α expression and improves hippocampal neuron numbers and memory in streptozotocin treated rats," European Journal of Pharmacology, vol. 765, pp. 482-487, 2015.
-
(2015)
European Journal of Pharmacology
, vol.765
, pp. 482-487
-
-
Solmaz, V.1
C¸inar, B.P.2
Yiǧittürk, G.3
C¸avus¸oǧlu, T.4
Tas¸kiran, D.5
Erbas¸, O.6
-
90
-
-
84895067918
-
Glucagon-like peptide-1 protects synaptic and learning functions from neuroinflammation in rodents
-
T. Iwai, T. Sawabe, K. Tanimitsu, M. Suzuki, S. Sasaki-Hamada, and J.-I. Oka, "Glucagon-like peptide-1 protects synaptic and learning functions from neuroinflammation in rodents," Journal of Neuroscience Research, vol. 92, no. 4, pp. 446-454, 2014.
-
(2014)
Journal of Neuroscience Research
, vol.92
, Issue.4
, pp. 446-454
-
-
Iwai, T.1
Sawabe, T.2
Tanimitsu, K.3
Suzuki, M.4
Sasaki-Hamada, S.5
Oka, J.-I.6
-
91
-
-
84886592674
-
Liraglutide can reverse memory impairment, synaptic loss and reduce plaque load in aged APP/PS1 mice, a model of Alzheimer's disease
-
P. L. McClean and C. Hölscher, "Liraglutide can reverse memory impairment, synaptic loss and reduce plaque load in aged APP/PS1 mice, a model of Alzheimer's disease," Neuropharmacology, vol. 76, pp. 57-67, 2014.
-
(2014)
Neuropharmacology
, vol.76
, pp. 57-67
-
-
McClean, P.L.1
Hölscher, C.2
-
92
-
-
84897829368
-
The incretin hormones glucagonlike peptide 1 and glucose-dependent insulinotropic polypeptide are neuroprotective in mouse models of Alzheimer's disease
-
C. Hölscher, "The incretin hormones glucagonlike peptide 1 and glucose-dependent insulinotropic polypeptide are neuroprotective in mouse models of Alzheimer's disease," Alzheimer's & Dementia, vol. 10, no. 1, pp. S47-S54, 2014.
-
(2014)
Alzheimer's & Dementia
, vol.10
, Issue.1
, pp. S47-S54
-
-
Hölscher, C.1
-
93
-
-
76749116176
-
Long-term inhibition of dipeptidyl peptidase-4 in Alzheimer's prone mice
-
M. D'Amico, C. Di Filippo, R. Marfella et al., "Long-term inhibition of dipeptidyl peptidase-4 in Alzheimer's prone mice," Experimental Gerontology, vol. 45, no. 3, pp. 202-207, 2010.
-
(2010)
Experimental Gerontology
, vol.45
, Issue.3
, pp. 202-207
-
-
D'Amico, M.1
Di Filippo, C.2
Marfella, R.3
-
94
-
-
70349334516
-
Exendin-4 protects dopaminergic neurons by inhibition of microglial activation and matrix metalloproteinase-3 expression in an animal model of Parkinson's disease
-
S. Kim, M. Moon, and S. Park, "Exendin-4 protects dopaminergic neurons by inhibition of microglial activation and matrix metalloproteinase-3 expression in an animal model of Parkinson's disease," The Journal of Endocrinology, vol. 202, no. 3, pp. 431-439, 2009.
-
(2009)
The Journal of Endocrinology
, vol.202
, Issue.3
, pp. 431-439
-
-
Kim, S.1
Moon, M.2
Park, S.3
-
95
-
-
84857185142
-
Exendin-4 improves steatohepatitis by increasing Sirt1 expression in high-fat diet-induced obese C57BL/6J mice
-
J. Lee, S.-W. Hong, S. W. Chae et al., "Exendin-4 improves steatohepatitis by increasing Sirt1 expression in high-fat diet-induced obese C57BL/6J mice," PLoS ONE, vol. 7, no. 2, Article ID e31394, 2012.
-
(2012)
PLoS ONE
, vol.7
, Issue.2
-
-
Lee, J.1
Hong, S.-W.2
Chae, S.W.3
-
96
-
-
84908632327
-
SIRT1 mediates the effect of GLP-1 receptor agonist exenatide on ameliorating hepatic steatosis
-
F. Xu, Z. Li, X. Zheng et al., "SIRT1 mediates the effect of GLP-1 receptor agonist exenatide on ameliorating hepatic steatosis," Diabetes, vol. 63, no. 11, pp. 3637-3646, 2014.
-
(2014)
Diabetes
, vol.63
, Issue.11
, pp. 3637-3646
-
-
Xu, F.1
Li, Z.2
Zheng, X.3
-
97
-
-
84924080351
-
Pilot study of liraglutide effects in non-alcoholic steatohepatitis and non-alcoholic fatty liver disease with glucose intolerance in Japanese patients (LEAN-J)
-
Y. Eguchi, Y. Kitajima, H. Hyogo et al., "Pilot study of liraglutide effects in non-alcoholic steatohepatitis and non-alcoholic fatty liver disease with glucose intolerance in Japanese patients (LEAN-J)," Hepatology Research, vol. 45, no. 3, pp. 269-278, 2015.
-
(2015)
Hepatology Research
, vol.45
, Issue.3
, pp. 269-278
-
-
Eguchi, Y.1
Kitajima, Y.2
Hyogo, H.3
-
98
-
-
84869111529
-
Exenatide plus metformin compared with metformin alone on β-cell function in patients with Type 2 diabetes
-
G. Derosa, I. G. Franzetti, F. Querci et al., "Exenatide plus metformin compared with metformin alone on β-cell function in patients with Type 2 diabetes," Diabetic Medicine, vol. 29, no. 12, pp. 1515-1523, 2012.
-
(2012)
Diabetic Medicine
, vol.29
, Issue.12
, pp. 1515-1523
-
-
Derosa, G.1
Franzetti, I.G.2
Querci, F.3
-
99
-
-
0142061945
-
Diabetic nephropathy is associated with low-grade inflammation in Type 1 diabetic patients
-
M. Saraheimo, A.-M. Teppo, C. Forsblom, J. Fagerudd, and P.- H. Groop, "Diabetic nephropathy is associated with low-grade inflammation in Type 1 diabetic patients," Diabetologia, vol. 46, no. 10, pp. 1402-1407, 2003.
-
(2003)
Diabetologia
, vol.46
, Issue.10
, pp. 1402-1407
-
-
Saraheimo, M.1
Teppo, A.-M.2
Forsblom, C.3
Fagerudd, J.4
Groop, P.- H.5
-
100
-
-
0036224765
-
Increased urinary albumin excretion, endothelial dysfunction, and chronic low-grade inflammation in type 2 diabetes: Progressive, interrelated, and independently associated with risk of death
-
C. D. A. Stehouwer, M.-A. Gall, J. W. R. Twisk, E. Knudsen, J. J. Emeis, and H.-H. Parving, "Increased urinary albumin excretion, endothelial dysfunction, and chronic low-grade inflammation in type 2 diabetes: progressive, interrelated, and independently associated with risk of death," Diabetes, vol. 51, no. 4, pp. 1157-1165, 2002.
-
(2002)
Diabetes
, vol.51
, Issue.4
, pp. 1157-1165
-
-
Stehouwer, C.D.A.1
Gall, M.-A.2
Twisk, J.W.R.3
Knudsen, E.4
Emeis, J.J.5
Parving, H.-H.6
-
101
-
-
79953826349
-
Glucagon-like peptide-1 receptor agonist ameliorates renal injury through its anti-inflammatory action without lowering blood glucose level in a rat model of type 1 diabetes
-
R. Kodera, K. Shikata, H. U. Kataoka et al., "Glucagon-like peptide-1 receptor agonist ameliorates renal injury through its anti-inflammatory action without lowering blood glucose level in a rat model of type 1 diabetes," Diabetologia, vol. 54, no. 4, pp. 965-978, 2011.
-
(2011)
Diabetologia
, vol.54
, Issue.4
, pp. 965-978
-
-
Kodera, R.1
Shikata, K.2
Kataoka, H.U.3
-
102
-
-
33947584619
-
Glucagon-like peptide 1 receptor expression in primary porcine proximal tubular cells
-
P. Schlatter, C. Beglinger, J. Drewe, and H. Gutmann, "Glucagon-like peptide 1 receptor expression in primary porcine proximal tubular cells," Regulatory Peptides, vol. 141, no. 1-3, pp. 120-128, 2007.
-
(2007)
Regulatory Peptides
, vol.141
, Issue.1-3
, pp. 120-128
-
-
Schlatter, P.1
Beglinger, C.2
Drewe, J.3
Gutmann, H.4
-
103
-
-
84955211839
-
Exendin-4 attenuates renal tubular injury by decreasing oxidative stress and inflammation in streptozotocin-induced diabetic mice
-
S. Sancar-Bas, S. Gezginci-Oktayoglu, and S. Bolkent, "Exendin-4 attenuates renal tubular injury by decreasing oxidative stress and inflammation in streptozotocin-induced diabetic mice," Growth Factors, vol. 33, no. 5-6, pp. 419-429, 2015.
-
(2015)
Growth Factors
, vol.33
, Issue.5-6
, pp. 419-429
-
-
Sancar-Bas, S.1
Gezginci-Oktayoglu, S.2
Bolkent, S.3
-
104
-
-
84964338729
-
Saxagliptin reduces renal tubulointerstitial inflammation, hypertrophy and fibrosis in diabetes
-
M. Gangadharan Komala, S. Gross, A. Zaky, C. Pollock, and U. Panchapakesan, "Saxagliptin reduces renal tubulointerstitial inflammation, hypertrophy and fibrosis in diabetes," Nephrology, 2015.
-
(2015)
Nephrology
-
-
Gangadharan Komala, M.1
Gross, S.2
Zaky, A.3
Pollock, C.4
Panchapakesan, U.5
-
105
-
-
84893704282
-
Dipeptidyl peptidase-4 inhibitor ameliorates early renal injury through its anti-inflammatory action in a rat model of type 1 diabetes
-
R. Kodera, K. Shikata, T. Takatsuka et al., "Dipeptidyl peptidase-4 inhibitor ameliorates early renal injury through its anti-inflammatory action in a rat model of type 1 diabetes," Biochemical and Biophysical Research Communications, vol. 443, no. 3, pp. 828-833, 2014.
-
(2014)
Biochemical and Biophysical Research Communications
, vol.443
, Issue.3
, pp. 828-833
-
-
Kodera, R.1
Shikata, K.2
Takatsuka, T.3
-
106
-
-
84929469873
-
Linagliptin blocks renal damage in type 1 diabetic rats by suppressing advanced glycation end products-receptor axis
-
S. Nakashima, T. Matsui, M. Takeuchi, and S.-I. Yamagishi, "Linagliptin blocks renal damage in type 1 diabetic rats by suppressing advanced glycation end products-receptor axis," Hormone and Metabolic Research, vol. 46, no. 10, pp. 717-721, 2014.
-
(2014)
Hormone and Metabolic Research
, vol.46
, Issue.10
, pp. 717-721
-
-
Nakashima, S.1
Matsui, T.2
Takeuchi, M.3
Yamagishi, S.-I.4
-
107
-
-
84927740133
-
Anti-inflammatory role of DPP-4 inhibitors in a nondiabetic model of glomerular injury
-
Y. Higashijima, T. Tanaka, J. Yamaguchi, S. Tanaka, and M. Nangaku, "Anti-inflammatory role of DPP-4 inhibitors in a nondiabetic model of glomerular injury," The American Journal of Physiology - Renal Physiology, vol. 308, no. 8, pp. F878-F887, 2015.
-
(2015)
The American Journal of Physiology - Renal Physiology
, vol.308
, Issue.8
, pp. F878-F887
-
-
Higashijima, Y.1
Tanaka, T.2
Yamaguchi, J.3
Tanaka, S.4
Nangaku, M.5
-
108
-
-
84889034019
-
Protection of glucagon-like peptide-1 in cisplatin-induced renal injury elucidates gut-kidney connection
-
D. Katagiri, Y. Hamasaki, K. Doi et al., "Protection of glucagon-like peptide-1 in cisplatin-induced renal injury elucidates gut-kidney connection," Journal of the American Society of Nephrology, vol. 24, no. 12, pp. 2034-2043, 2013.
-
(2013)
Journal of the American Society of Nephrology
, vol.24
, Issue.12
, pp. 2034-2043
-
-
Katagiri, D.1
Hamasaki, Y.2
Doi, K.3
-
109
-
-
84886165527
-
Exendin-4 and sitagliptin protect kidney from ischemia-reperfusion injury through suppressing oxidative stress and inflammatory reaction
-
Y.-T. Chen, T.-H. Tsai, C.-C. Yang et al., "Exendin-4 and sitagliptin protect kidney from ischemia-reperfusion injury through suppressing oxidative stress and inflammatory reaction," Journal of Translational Medicine, vol. 11, article 270, 2013.
-
(2013)
Journal of Translational Medicine
, vol.11
-
-
Chen, Y.-T.1
Tsai, T.-H.2
Yang, C.-C.3
-
110
-
-
84940504492
-
Glucagon like peptide-1 (GLP-1) modulates OVA-induced airway inflammation and mucus secretion involving a protein kinase A (PKA)-dependent nuclear factor-κB (NF-κB) signaling pathway in mice
-
T. Zhu, X.-L. Wu, W. Zhang, and M. Xiao, "Glucagon like peptide-1 (GLP-1) modulates OVA-induced airway inflammation and mucus secretion involving a protein kinase A (PKA)-dependent nuclear factor-κB (NF-κB) signaling pathway in mice," International Journal of Molecular Sciences, vol. 16, no. 9, pp. 20195-20211, 2015.
-
(2015)
International Journal of Molecular Sciences
, vol.16
, Issue.9
, pp. 20195-20211
-
-
Zhu, T.1
Wu, X.-L.2
Zhang, W.3
Xiao, M.4
-
111
-
-
84944166687
-
GLP-1 receptor agonist exenatide attenuates the detrimental effects of obesity on inflammatory profile in testis and sperm quality in mice
-
E. Zhang, F. Xu, H. Liang et al., "GLP-1 receptor agonist exenatide attenuates the detrimental effects of obesity on inflammatory profile in testis and sperm quality in mice," American Journal of Reproductive Immunology, vol. 74, no. 5, pp. 457-466, 2015.
-
(2015)
American Journal of Reproductive Immunology
, vol.74
, Issue.5
, pp. 457-466
-
-
Zhang, E.1
Xu, F.2
Liang, H.3
-
112
-
-
79952987886
-
Paternal body mass index is associated with decreased blastocyst development and reduced live birth rates following assisted reproductive technology
-
H. W. Bakos, R. C. Henshaw, M. Mitchell, and M. Lane, "Paternal body mass index is associated with decreased blastocyst development and reduced live birth rates following assisted reproductive technology," Fertility and Sterility, vol. 95, no. 5, pp. 1700-1704, 2011.
-
(2011)
Fertility and Sterility
, vol.95
, Issue.5
, pp. 1700-1704
-
-
Bakos, H.W.1
Henshaw, R.C.2
Mitchell, M.3
Lane, M.4
-
113
-
-
80054708816
-
Glucagon-like peptide-1 (GLP-1) receptor agonists, obesity and psoriasis: Diabetes meets dermatology
-
D. J. Drucker and C. F. Rosen, "Glucagon-like peptide-1 (GLP-1) receptor agonists, obesity and psoriasis: diabetes meets dermatology," Diabetologia, vol. 54, no. 11, pp. 2741-2744, 2011.
-
(2011)
Diabetologia
, vol.54
, Issue.11
, pp. 2741-2744
-
-
Drucker, D.J.1
Rosen, C.F.2
-
114
-
-
84896727316
-
Improvement in psoriasis after treatment with the glucagon-like peptide-1 receptor agonist liraglutide
-
A. Faurschou, F. K. Knop, J. P. Thyssen, C. Zachariae, L. Skov, and T. Vilsbøll, "Improvement in psoriasis after treatment with the glucagon-like peptide-1 receptor agonist liraglutide," Acta Diabetologica, vol. 51, no. 1, pp. 147-150, 2014.
-
(2014)
Acta Diabetologica
, vol.51
, Issue.1
, pp. 147-150
-
-
Faurschou, A.1
Knop, F.K.2
Thyssen, J.P.3
Zachariae, C.4
Skov, L.5
Vilsbøll, T.6
-
115
-
-
84928244016
-
Gliptin and GLP-1 analog treatment improves survival and vascular inflammation/dysfunction in animals with lipopolysaccharide-induced endotoxemia
-
S. Steven, M. Hausding, S. Kröller-Schön et al., "Gliptin and GLP-1 analog treatment improves survival and vascular inflammation/dysfunction in animals with lipopolysaccharide-induced endotoxemia," Basic Research in Cardiology, vol. 110, no. 2, article 6, 2015.
-
(2015)
Basic Research in Cardiology
, vol.110
, Issue.2
-
-
Steven, S.1
Hausding, M.2
Kröller-Schön, S.3
|