-
2
-
-
0002025725
-
On the treatment of Diabetus mellitus by acid extract of Duodenal Mucous Membrane
-
Moore B. On the treatment of Diabetus mellitus by acid extract of Duodenal Mucous Membrane. Biochem J 1906. 1:28-38.
-
(1906)
Biochem J
, vol.1
, pp. 28-38
-
-
Moore, B.1
-
3
-
-
0013942426
-
Stimulation of release of insulin by an extract of intestinal mucosa
-
Dupre J, Beck JC. Stimulation of release of insulin by an extract of intestinal mucosa. Diabetes 1966. 15:555-559.
-
(1966)
Diabetes
, vol.15
, pp. 555-559
-
-
Dupre, J.1
Beck, J.C.2
-
6
-
-
0019124304
-
Gastric inhibitory polypeptide (GIP) and insulin release after small-bowel resection in man
-
Lauritsen KB, Moody AJ, Christensen KC, Lindkaer Jensen S. Gastric inhibitory polypeptide (GIP) and insulin release after small-bowel resection in man. Scand J Gastroenterol 1980. 15:833-840.
-
(1980)
Scand J Gastroenterol
, vol.15
, pp. 833-840
-
-
Lauritsen, K.B.1
Moody, A.J.2
Christensen, K.C.3
Lindkaer, J.S.4
-
7
-
-
0023107555
-
Insulinotropin: Glucagon-like peptide I (7-37) co-encoded in the glucagon gene is a potent stimulator of insulin release in the perfused rat pancreas
-
Mojsov S, Weir GC, Habener JF. Insulinotropin: glucagon-like peptide I (7-37) co-encoded in the glucagon gene is a potent stimulator of insulin release in the perfused rat pancreas. J Clin Invest 1987. 79:616-619.
-
(1987)
J Clin Invest
, vol.79
, pp. 616-619
-
-
Mojsov, S.1
Weir, G.C.2
Habener, J.F.3
-
8
-
-
0023638829
-
Glucagon-like peptide-1 7-36: A physiological incretin in man
-
Kreymann B, Williams G, Ghatei MA, Bloom SR. Glucagon-like peptide-1 7-36: a physiological incretin in man. Lancet 1987. 2:1300-1304.
-
(1987)
Lancet
, vol.2
, pp. 1300-1304
-
-
Kreymann, B.1
Williams, G.2
Ghatei, M.A.3
Bloom, S.R.4
-
9
-
-
0015606796
-
Cellular localization of gastric inhibitory polypeptide in the duodenum and jejunum
-
Polak JM, Bloom SR, Kuzio M, Brown JC, Pearse AG. Cellular localization of gastric inhibitory polypeptide in the duodenum and jejunum. Gut 1973. 14:284-288.
-
(1973)
Gut
, vol.14
, pp. 284-288
-
-
Polak, J.M.1
Bloom, S.R.2
Kuzio, M.3
Brown, J.C.4
Pearse, A.G.5
-
10
-
-
0016734622
-
Identification of the intestinal cell storing gastric inhibitory peptide
-
Buffa R, Polak JM, Pearse AG, Solcia E, Grimelius L, Capella C. Identification of the intestinal cell storing gastric inhibitory peptide. Histochemistry 1975. 43:249-255.
-
(1975)
Histochemistry
, vol.43
, pp. 249-255
-
-
Buffa, R.1
Polak, J.M.2
Pearse, A.G.3
Solcia, E.4
Grimelius, L.5
Capella, C.6
-
11
-
-
0022971804
-
Glucagon-like peptides GLP-1 and GLP-2, predicted products of the glucagon gene, are secreted separately from pig small intestine but not pancreas
-
Orskov C, Holst JJ, Knuhtsen S, Baldissera FG, Poulsen SS, Nielsen OV. Glucagon-like peptides GLP-1 and GLP-2, predicted products of the glucagon gene, are secreted separately from pig small intestine but not pancreas. Endocrinology 1986. 119:1467-1475.
-
(1986)
Endocrinology
, vol.119
, pp. 1467-1475
-
-
Orskov, C.1
Holst, J.J.2
Knuhtsen, S.3
Baldissera, F.G.4
Poulsen, S.S.5
Nielsen, O.V.6
-
12
-
-
0029921394
-
Effects of fasting, refeeding, and intraluminal triglyceride on proglucagon expression in jejunum and ileum
-
Hoyt EC, Lund PK, Winesett DE, Fuller CR, Ghatei MA, Bloom SR, Ulshen MH. Effects of fasting, refeeding, and intraluminal triglyceride on proglucagon expression in jejunum and ileum. Diabetes 1996. 45:434-439.
-
(1996)
Diabetes
, vol.45
, pp. 434-439
-
-
Hoyt, E.C.1
Lund, P.K.2
Winesett, D.E.3
Fuller, C.R.4
Ghatei, M.A.5
Bloom, S.R.6
Ulshen, M.H.7
-
13
-
-
0038121744
-
Both GLP-1 and GIP are insulinotropic at basal and postprandial glucose levels and contribute nearly equally to the incretin effect of a meal in healthy subjects
-
Vilsboll T, Krarup T, Madsbad S, Holst JJ. Both GLP-1 and GIP are insulinotropic at basal and postprandial glucose levels and contribute nearly equally to the incretin effect of a meal in healthy subjects. Regul Pept 2003. 114:115-121.
-
(2003)
Regul Pept
, vol.114
, pp. 115-121
-
-
Vilsboll, T.1
Krarup, T.2
Madsbad, S.3
Holst, J.J.4
-
14
-
-
0027391607
-
Preserved incretin activity of glucagon-like peptide 1 [7-36 amide] but not of synthetic human gastric inhibitory polypeptide in patients with type-2 diabetes mellitus
-
Nauck MA, Heimesaat MM, Orskov C, Holst JJ, Ebert R, Creutzfeldt W. Preserved incretin activity of glucagon-like peptide 1 [7-36 amide] but not of synthetic human gastric inhibitory polypeptide in patients with type-2 diabetes mellitus. J Clin Invest 1993. 91:301-307.
-
(1993)
J Clin Invest
, vol.91
, pp. 301-307
-
-
Nauck, M.A.1
Heimesaat, M.M.2
Orskov, C.3
Holst, J.J.4
Ebert, R.5
Creutzfeldt, W.6
-
15
-
-
0028224617
-
The insulinotropic actions of glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (7-37) in normal and diabetic subjects
-
Elahi D, McAloon-Dyke M, Fukagawa NK, Meneilly GS, Sclater AL, Minaker KL, Habener JF, Andersen DK. The insulinotropic actions of glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (7-37) in normal and diabetic subjects. Regul Pept 1994. 51:63-74.
-
(1994)
Regul Pept
, vol.51
, pp. 63-74
-
-
Elahi, D.1
McAloon-Dyke, M.2
Fukagawa, N.K.3
Meneilly, G.S.4
Sclater, A.L.5
Minaker, K.L.6
Habener, J.F.7
Andersen, D.K.8
-
16
-
-
0037312821
-
The influence of GLP-1 on glucose-stimulated insulin secretion: Effects on beta-cell sensitivity in type 2 and nondiabetic subjects
-
Kjems LL, Holst JJ, Volund A, Madsbad S. The influence of GLP-1 on glucose-stimulated insulin secretion: effects on beta-cell sensitivity in type 2 and nondiabetic subjects. Diabetes 2003. 52:380-386.
-
(2003)
Diabetes
, vol.52
, pp. 380-386
-
-
Kjems, L.L.1
Holst, J.J.2
Volund, A.3
Madsbad, S.4
-
17
-
-
79953165707
-
GIP does not potentiate the antidiabetic effects of GLP-1 in hyperglycemic patients with type 2 diabetes
-
Mentis N, Vardarli I, Kothe LD, Holst JJ, Deacon CF, Theodorakis M, Meier JJ, Nauck MA. GIP does not potentiate the antidiabetic effects of GLP-1 in hyperglycemic patients with type 2 diabetes. Diabetes 2011. 60:1270-1276.
-
(2011)
Diabetes
, vol.60
, pp. 1270-1276
-
-
Mentis, N.1
Vardarli, I.2
Kothe, L.D.3
Holst, J.J.4
Deacon, C.F.5
Theodorakis, M.6
Meier, J.J.7
Nauck, M.A.8
-
18
-
-
0023008693
-
Preproglucagon gene expression in pancreas and intestine diversifies at the level of post-translational processing
-
Mojsov S, Heinrich G, Wilson IB, Ravazzola M, Orci L, Habener JF. Preproglucagon gene expression in pancreas and intestine diversifies at the level of post-translational processing. J Biol Chem 1986. 261:11880-11889.
-
(1986)
J Biol Chem
, vol.261
, pp. 11880-11889
-
-
Mojsov, S.1
Heinrich, G.2
Wilson, I.B.3
Ravazzola, M.4
Orci, L.5
Habener, J.F.6
-
19
-
-
0023005768
-
Proglucagon processing in a rat islet cell line resembles phenotype of intestine rather than pancreas
-
Philippe J, Mojsov S, Drucker DJ, Habener JF. Proglucagon processing in a rat islet cell line resembles phenotype of intestine rather than pancreas. Endocrinology 1986. 119:2833-2839.
-
(1986)
Endocrinology
, vol.119
, pp. 2833-2839
-
-
Philippe, J.1
Mojsov, S.2
Drucker, D.J.3
Habener, J.F.4
-
20
-
-
0031029936
-
Distribution of glucagon-like peptide-1 and other preproglucagon- derived peptides in the rat hypothalamus and brainstem
-
Larsen PJ, Tang-Christensen M, Holst JJ, Orskov C. Distribution of glucagon-like peptide-1 and other preproglucagon- derived peptides in the rat hypothalamus and brainstem. Neuroscience 1997. 77:257-270.
-
(1997)
Neuroscience
, vol.77
, pp. 257-270
-
-
Larsen, P.J.1
Tang-Christensen, M.2
Holst, J.J.3
Orskov, C.4
-
21
-
-
0028281773
-
Tissue and plasma concentrations of amidated and glycine-extended glucagon-like peptide I in humans
-
Orskov C, Rabenhoj L, Wettergren A, Kofod H, Holst JJ. Tissue and plasma concentrations of amidated and glycine-extended glucagon-like peptide I in humans. Diabetes 1994. 43:535-539.
-
(1994)
Diabetes
, vol.43
, pp. 535-539
-
-
Orskov, C.1
Rabenhoj, L.2
Wettergren, A.3
Kofod, H.4
Holst, J.J.5
-
22
-
-
0024421193
-
Characterization of glucagon-like peptide-1-(7-36)amide in the hypothalamus
-
Kreymann B, Ghatei MA, Burnet P, Williams G, Kanse S, Diani AR, Bloom SR. Characterization of glucagon-like peptide-1-(7-36)amide in the hypothalamus. Brain Res 1989. 502:325-331.
-
(1989)
Brain Res
, vol.502
, pp. 325-331
-
-
Kreymann, B.1
Ghatei, M.A.2
Burnet, P.3
Williams, G.4
Kanse, S.5
Diani, A.R.6
Bloom, S.R.7
-
23
-
-
75349091535
-
Molecular mechanisms underlying nutrient detection by incretin-secreting cells
-
Reimann F. Molecular mechanisms underlying nutrient detection by incretin-secreting cells. Int Dairy J 2010. 20:236-242.
-
(2010)
Int Dairy J
, vol.20
, pp. 236-242
-
-
Reimann, F.1
-
24
-
-
0037414781
-
Glucagon-like peptide-1 receptor signaling modulates beta cell apoptosis
-
Li Y, Hansotia T, Yusta B, Ris F, Halban PA, Drucker DJ. Glucagon-like peptide-1 receptor signaling modulates beta cell apoptosis. J Biol Chem 2003. 278:471-478.
-
(2003)
J Biol Chem
, vol.278
, pp. 471-478
-
-
Li, Y.1
Hansotia, T.2
Yusta, B.3
Ris, F.4
Halban, P.A.5
Drucker, D.J.6
-
25
-
-
0345374580
-
Glucagon-like peptide 1 inhibits cell apoptosis and improves glucose responsiveness of freshly isolated human islets
-
Farilla L, Bulotta A, Hirshberg B, Li Calzi S, Khoury N, Noushmehr H, Bertolotto C, Di Mario U, Harlan DM, Perfetti R. Glucagon-like peptide 1 inhibits cell apoptosis and improves glucose responsiveness of freshly isolated human islets. Endocrinology 2003. 144:5149-5158.
-
(2003)
Endocrinology
, vol.144
, pp. 5149-5158
-
-
Farilla, L.1
Bulotta, A.2
Hirshberg, B.3
li Calzi, S.4
Khoury, N.5
Noushmehr, H.6
Bertolotto, C.7
di Mario, U.8
Harlan, D.M.9
Perfetti, R.10
-
26
-
-
79953320085
-
Expression and spatial heterogeneity of dipeptidyl peptidases in endothelial cells of conduct vessels and capillaries
-
Matheeussen V, Baerts L, De Meyer G, De Keulenaer G, Van der Veken P, Augustyns K, Dubois V, Scharpe S, De Meester I. Expression and spatial heterogeneity of dipeptidyl peptidases in endothelial cells of conduct vessels and capillaries. Biol Chem 2011. 392(3):189-198.
-
(2011)
Biol Chem
, vol.392
, Issue.3
, pp. 189-198
-
-
Matheeussen, V.1
Baerts, L.2
de Meyer, G.3
de Keulenaer, G.4
van der Veken, P.5
Augustyns, K.6
Dubois, V.7
Scharpe, S.8
de Meester, I.9
-
27
-
-
12244281855
-
Circulation and degradation of GIP and GLP-1
-
Deacon CF. Circulation and degradation of GIP and GLP-1. Horm Metab Res 2004. 36:761-765.
-
(2004)
Horm Metab Res
, vol.36
, pp. 761-765
-
-
Deacon, C.F.1
-
28
-
-
78751648843
-
Dipeptidyl peptidase IV in the hypothalamus and hippocampus of monosodium glutamate obese and food-deprived rats
-
Alponti RF, Frezzatti R, Barone JM, Alegre Vde S, Silveira PF. Dipeptidyl peptidase IV in the hypothalamus and hippocampus of monosodium glutamate obese and food-deprived rats. Metabolism 2011. 60:234-242.
-
(2011)
Metabolism
, vol.60
, pp. 234-242
-
-
Alponti, R.F.1
Frezzatti, R.2
Barone, J.M.3
Alegre, V.S.4
Silveira, P.F.5
-
29
-
-
77956301808
-
Preproglucagon derived peptides GLP-1, GLP-2 and oxyntomodulin in the CNS: Role of peripherally secreted and centrally produced peptides
-
Vrang N, Larsen PJ. Preproglucagon derived peptides GLP-1, GLP-2 and oxyntomodulin in the CNS: role of peripherally secreted and centrally produced peptides. Prog Neurobiol 2010. 92:442-462.
-
(2010)
Prog Neurobiol
, vol.92
, pp. 442-462
-
-
Vrang, N.1
Larsen, P.J.2
-
30
-
-
24944436267
-
Neutral endopeptidase 24.11 and dipeptidyl peptidase IV are both mediators of the degradation of glucagon-like peptide 1 in the anaesthetised pig
-
Plamboeck A, Holst JJ, Carr RD, Deacon CF. Neutral endopeptidase 24.11 and dipeptidyl peptidase IV are both mediators of the degradation of glucagon-like peptide 1 in the anaesthetised pig. Diabetologia 2005. 48:1882-1890.
-
(2005)
Diabetologia
, vol.48
, pp. 1882-1890
-
-
Plamboeck, A.1
Holst, J.J.2
Carr, R.D.3
Deacon, C.F.4
-
31
-
-
0029111540
-
Characterisation of the processing by human neutral endopeptidase 24.11 of GLP-1(7-36) amide and comparison of the substrate specificity of the enzyme for other glucagonlike peptides
-
Hupe-Sodmann K, McGregor GP, Bridenbaugh R, Goke R, Goke B, Thole H, Zimmermann B, Voigt K. Characterisation of the processing by human neutral endopeptidase 24.11 of GLP-1(7-36) amide and comparison of the substrate specificity of the enzyme for other glucagonlike peptides. Regul Pept 1995. 58:149-156.
-
(1995)
Regul Pept
, vol.58
, pp. 149-156
-
-
Hupe-Sodmann, K.1
McGregor, G.P.2
Bridenbaugh, R.3
Goke, R.4
Goke, B.5
Thole, H.6
Zimmermann, B.7
Voigt, K.8
-
32
-
-
17844399596
-
Glucagon-like peptide-1 mediates the therapeutic actions of DPP-IV inhibitors
-
Holst JJ, Deacon CF. Glucagon-like peptide-1 mediates the therapeutic actions of DPP-IV inhibitors. Diabetologia 2005. 48:612-615.
-
(2005)
Diabetologia
, vol.48
, pp. 612-615
-
-
Holst, J.J.1
Deacon, C.F.2
-
33
-
-
0034880655
-
Determinants of the impaired secretion of glucagon-like peptide-1 in type 2 diabetic patients
-
Toft-Nielsen MB, Damholt MB, Madsbad S, Hilsted LM, Hughes TE, Michelsen BK, Holst JJ. Determinants of the impaired secretion of glucagon-like peptide-1 in type 2 diabetic patients. J Clin Endocrinol Metab 2001. 86:3717-3723.
-
(2001)
J Clin Endocrinol Metab
, vol.86
, pp. 3717-3723
-
-
Toft-Nielsen, M.B.1
Damholt, M.B.2
Madsbad, S.3
Hilsted, L.M.4
Hughes, T.E.5
Michelsen, B.K.6
Holst, J.J.7
-
34
-
-
79952310049
-
Secretion of glucagon-like peptide-1 (GLP-1) in type 2 diabetes: What is up, what is down?
-
Nauck MA, Vardarli I, Deacon CF, Holst JJ, Meier JJ. Secretion of glucagon-like peptide-1 (GLP-1) in type 2 diabetes: what is up, what is down? Diabetologia 2011. 54:10-18.
-
(2011)
Diabetologia
, vol.54
, pp. 10-18
-
-
Nauck, M.A.1
Vardarli, I.2
Deacon, C.F.3
Holst, J.J.4
Meier, J.J.5
-
35
-
-
6344241190
-
Structurally modified analogues of glucagon-like peptide-1 (GLP- 1) and glucose-dependent insulinotropic polypeptide (GIP) as future antidiabetic agents
-
Green BD, Gault VA, O'Harte F P, Flatt PR. Structurally modified analogues of glucagon-like peptide-1 (GLP- 1) and glucose-dependent insulinotropic polypeptide (GIP) as future antidiabetic agents. Curr Pharm Des 2004. 10:3651-3662.
-
(2004)
Curr Pharm Des
, vol.10
, pp. 3651-3662
-
-
Green, B.D.1
Gault, V.A.2
O'Harte, F.P.3
Flatt, P.R.4
-
36
-
-
72449121795
-
Leptin and the systems neuroscience of meal size control
-
Grill HJ. Leptin and the systems neuroscience of meal size control. Front Neuroendocrinol 2010. 31:61-78.
-
(2010)
Front Neuroendocrinol
, vol.31
, pp. 61-78
-
-
Grill, H.J.1
-
37
-
-
34247639607
-
Characterization of brainstem preproglucagon projections to the paraventricular and dorsomedial hypothalamic nuclei
-
Vrang N, Hansen M, Larsen PJ, Tang-Christensen M. Characterization of brainstem preproglucagon projections to the paraventricular and dorsomedial hypothalamic nuclei. Brain Res 2007. 1149:118-126.
-
(2007)
Brain Res
, vol.1149
, pp. 118-126
-
-
Vrang, N.1
Hansen, M.2
Larsen, P.J.3
Tang-Christensen, M.4
-
38
-
-
36749000010
-
Upregulation of the brainstem preproglucagon system in the obese Zucker rat
-
Vrang N, Larsen PJ, Jensen PB, Lykkegaard K, Artmann A, Larsen LK, Tang-Christensen M. Upregulation of the brainstem preproglucagon system in the obese Zucker rat. Brain Res 2008. 1187:116-124.
-
(2008)
Brain Res
, vol.1187
, pp. 116-124
-
-
Vrang, N.1
Larsen, P.J.2
Jensen, P.B.3
Lykkegaard, K.4
Artmann, A.5
Larsen, L.K.6
Tang-Christensen, M.7
-
39
-
-
79953189360
-
Preproglucagon neurons project widely to autonomic control areas in the mouse brain
-
Llewellyn-Smith IJ, Reimann F, Gribble FM, Trapp S. Preproglucagon neurons project widely to autonomic control areas in the mouse brain. Neuroscience 2011. 180:111-121.
-
(2011)
Neuroscience
, vol.180
, pp. 111-121
-
-
Llewellyn-Smith, I.J.1
Reimann, F.2
Gribble, F.M.3
Trapp, S.4
-
40
-
-
0023950336
-
Distribution of glucagonlike peptide I (GLP-I), glucagon, and glicentin in the rat brain: An immunocytochemical study
-
Jin SL, Han VK, Simmons JG, Towle AC, Lauder JM, Lund PK. Distribution of glucagonlike peptide I (GLP-I), glucagon, and glicentin in the rat brain: an immunocytochemical study. J Comp Neurol 1988. 271:519-532.
-
(1988)
J Comp Neurol
, vol.271
, pp. 519-532
-
-
Jin, S.L.1
Han, V.K.2
Simmons, J.G.3
Towle, A.C.4
Lauder, J.M.5
Lund, P.K.6
-
41
-
-
0033545166
-
Distribution of pre-pro-glucagon and glucagon-like peptide-1 receptor messenger RNAs in the rat central nervous system
-
Merchenthaler I, Lane M, Shughrue P. Distribution of pre-pro-glucagon and glucagon-like peptide-1 receptor messenger RNAs in the rat central nervous system. J Comp Neurol 1999. 403:261-280.
-
(1999)
J Comp Neurol
, vol.403
, pp. 261-280
-
-
Merchenthaler, I.1
Lane, M.2
Shughrue, P.3
-
42
-
-
0028900758
-
Tissue-specific expression of the human receptor for glucagon-like peptide-I: Brain, heart and pancreatic forms have the same deduced amino acid sequences
-
Wei Y, Mojsov S. Tissue-specific expression of the human receptor for glucagon-like peptide-I: brain, heart and pancreatic forms have the same deduced amino acid sequences. FEBS Lett 1995. 358:219-224.
-
(1995)
FEBS Lett
, vol.358
, pp. 219-224
-
-
Wei, Y.1
Mojsov, S.2
-
43
-
-
0030056878
-
Expression of the glucagon-like peptide-1 receptor gene in rat brain
-
Alvarez E, Roncero I, Chowen JA, Thorens B, Blazquez E. Expression of the glucagon-like peptide-1 receptor gene in rat brain. J Neurochem 1996. 66:920-927.
-
(1996)
J Neurochem
, vol.66
, pp. 920-927
-
-
Alvarez, E.1
Roncero, I.2
Chowen, J.A.3
Thorens, B.4
Blazquez, E.5
-
44
-
-
0027425034
-
Cloning and functional expression of the human islet GLP-1 receptor. Demonstration that exendin-4 is an agonist and exendin-(9-39) an antagonist of the receptor
-
Thorens B, Porret A, Buhler L, Deng SP, Morel P, Widmann C. Cloning and functional expression of the human islet GLP-1 receptor. Demonstration that exendin-4 is an agonist and exendin-(9-39) an antagonist of the receptor. Diabetes 1993. 42:1678-1682.
-
(1993)
Diabetes
, vol.42
, pp. 1678-1682
-
-
Thorens, B.1
Porret, A.2
Buhler, L.3
Deng, S.P.4
Morel, P.5
Widmann, C.6
-
45
-
-
0026775150
-
Expression cloning of the pancreatic beta cell receptor for the gluco-incretin hormone glucagon-like peptide 1
-
Thorens B. Expression cloning of the pancreatic beta cell receptor for the gluco-incretin hormone glucagon-like peptide 1. Proc Natl Acad Sci U S A 1992. 89:8641-8645.
-
(1992)
Proc Natl Acad Sci U S A
, vol.89
, pp. 8641-8645
-
-
Thorens, B.1
-
46
-
-
0027435283
-
Cloning and functional expression of the human glucagon-like peptide-1 (GLP-1) receptor
-
Dillon JS, Tanizawa Y, Wheeler MB, Leng XH, Ligon BB, Rabin DU, Yoo-Warren H, Permutt MA, Boyd AE 3rd. Cloning and functional expression of the human glucagon-like peptide-1 (GLP-1) receptor. Endocrinology 1993. 133:1907-1910.
-
(1993)
Endocrinology
, vol.133
, pp. 1907-1910
-
-
Dillon, J.S.1
Tanizawa, Y.2
Wheeler, M.B.3
Leng, X.H.4
Ligon, B.B.5
Rabin, D.U.6
Yoo-Warren, H.7
Permutt, M.A.8
Boyd III, A.E.9
-
47
-
-
0037373183
-
The glucagon receptor family
-
International Union of Pharmacology. XXXV
-
Mayo KE, Miller LJ, Bataille D, Dalle S, Goke B, Thorens B, Drucker DJ. International Union of Pharmacology. XXXV. The glucagon receptor family. Pharmacol Rev 2003. 55:167-194.
-
(2003)
Pharmacol Rev
, vol.55
, pp. 167-194
-
-
Mayo, K.E.1
Miller, L.J.2
Bataille, D.3
Dalle, S.4
Goke, B.5
Thorens, B.6
Drucker, D.J.7
-
48
-
-
0344357096
-
Glucagon-like peptide I stimulates insulin gene expression and increases cyclic AMP levels in a rat islet cell line
-
Drucker DJ, Philippe J, Mojsov S, Chick WL, Habener JF. Glucagon-like peptide I stimulates insulin gene expression and increases cyclic AMP levels in a rat islet cell line. Proc Natl Acad Sci U S A 1987. 84:3434-3438.
-
(1987)
Proc Natl Acad Sci U S A
, vol.84
, pp. 3434-3438
-
-
Drucker, D.J.1
Philippe, J.2
Mojsov, S.3
Chick, W.L.4
Habener, J.F.5
-
49
-
-
0027164996
-
Functional expression of the rat glucagons like peptide-I receptor, evidence for coupling to both adenylyl cyclase and phospholipase-C
-
Wheeler MB, Lu M, Dillon JS, Leng XH, Chen C, Boyd AE 3rd. Functional expression of the rat glucagons like peptide-I receptor, evidence for coupling to both adenylyl cyclase and phospholipase-C. Endocrinology 1993. 133:57-62.
-
(1993)
Endocrinology
, vol.133
, pp. 57-62
-
-
Wheeler, M.B.1
Lu, M.2
Dillon, J.S.3
Leng, X.H.4
Chen, C.5
Boyd III, A.E.6
-
50
-
-
33749396593
-
Glucagon-like peptide 1 activates protein kinase C through Ca2+-dependent activation of phospholipase C in insulin-secreting cells
-
Suzuki Y, Zhang H, Saito N, Kojima I, Urano T, Mogami H. Glucagon-like peptide 1 activates protein kinase C through Ca2+-dependent activation of phospholipase C in insulin-secreting cells. J Biol Chem 2006. 281:28499-28507.
-
(2006)
J Biol Chem
, vol.281
, pp. 28499-28507
-
-
Suzuki, Y.1
Zhang, H.2
Saito, N.3
Kojima, I.4
Urano, T.5
Mogami, H.6
-
51
-
-
0028867442
-
Distribution of GLP-1 binding sites in the rat brain: Evidence that exendin-4 is a ligand of brain GLP-1 binding sites
-
Goke R, Larsen PJ, Mikkelsen JD, Sheikh SP. Distribution of GLP-1 binding sites in the rat brain: evidence that exendin-4 is a ligand of brain GLP-1 binding sites. Eur J Neurosci 1995. 7:2294-2300.
-
(1995)
Eur J Neurosci
, vol.7
, pp. 2294-2300
-
-
Goke, R.1
Larsen, P.J.2
Mikkelsen, J.D.3
Sheikh, S.P.4
-
52
-
-
0029806072
-
Glucagonlike peptide-1 receptor (GLP1-R) mRNA in the rat hypothalamus
-
Shughrue PJ, Lane MV, Merchenthaler I. Glucagonlike peptide-1 receptor (GLP1-R) mRNA in the rat hypothalamus. Endocrinology 1996. 137:5159-5162.
-
(1996)
Endocrinology
, vol.137
, pp. 5159-5162
-
-
Shughrue, P.J.1
Lane, M.V.2
Merchenthaler, I.3
-
53
-
-
13644268431
-
The expression of GLP-1 receptor mRNA and protein allows the effect of GLP-1 on glucose metabolism in the human hypothalamus and brainstem
-
Alvarez E, Martinez MD, Roncero I, Chowen JA, Garcia-Cuartero B, Gispert JD, Sanz C, Vazquez P, Maldonado A, de Caceres J, et al. The expression of GLP-1 receptor mRNA and protein allows the effect of GLP-1 on glucose metabolism in the human hypothalamus and brainstem. J Neurochem 2005. 92:798-806.
-
(2005)
J Neurochem
, vol.92
, pp. 798-806
-
-
Alvarez, E.1
Martinez, M.D.2
Roncero, I.3
Chowen, J.A.4
Garcia-Cuartero, B.5
Gispert, J.D.6
Sanz, C.7
Vazquez, P.8
Maldonado, A.9
de Caceres, J.10
-
54
-
-
0345726358
-
Glucagonlike peptide-1-responsive catecholamine neurons in the area postrema link peripheral glucagon-like peptide-1 with central autonomic control sites
-
Yamamoto H, Kishi T, Lee CE, Choi BJ, Fang H, Hollenberg AN, Drucker DJ, Elmquist JK. Glucagonlike peptide-1-responsive catecholamine neurons in the area postrema link peripheral glucagon-like peptide-1 with central autonomic control sites. J Neurosci 2003. 23:2939-2946.
-
(2003)
J Neurosci
, vol.23
, pp. 2939-2946
-
-
Yamamoto, H.1
Kishi, T.2
Lee, C.E.3
Choi, B.J.4
Fang, H.5
Hollenberg, A.N.6
Drucker, D.J.7
Elmquist, J.K.8
-
55
-
-
0035434115
-
Glucose competence of the hepatoportal vein sensor requires the presence of an activated glucagon-like peptide-1 receptor
-
Burcelin R, Da Costa A, Drucker D, Thorens B. Glucose competence of the hepatoportal vein sensor requires the presence of an activated glucagon-like peptide-1 receptor. Diabetes 2001. 50:1720-1728.
-
(2001)
Diabetes
, vol.50
, pp. 1720-1728
-
-
Burcelin, R.1
da Costa, A.2
Drucker, D.3
Thorens, B.4
-
56
-
-
0842325280
-
Receptor gene expression of glucagon-like peptide- 1, but not glucose-dependent insulinotropic polypeptide, in rat nodose ganglion cells
-
Nakagawa A, Satake H, Nakabayashi H, Nishizawa M, Furuya K, Nakano S, Kigoshi T, Nakayama K, Uchida K. Receptor gene expression of glucagon-like peptide- 1, but not glucose-dependent insulinotropic polypeptide, in rat nodose ganglion cells. Auton Neurosci 2004. 110:36-43.
-
(2004)
Auton Neurosci
, vol.110
, pp. 36-43
-
-
Nakagawa, A.1
Satake, H.2
Nakabayashi, H.3
Nishizawa, M.4
Furuya, K.5
Nakano, S.6
Kigoshi, T.7
Nakayama, K.8
Uchida, K.9
-
57
-
-
0033696456
-
Portal GLP-1 administration in rats augments the insulin response to glucose via neuronal mechanisms
-
Balkan B, Li X. Portal GLP-1 administration in rats augments the insulin response to glucose via neuronal mechanisms. Am J Physiol Regul Integr Comp Physiol 2000. 279:R1449-R1454.
-
(2000)
Am J Physiol Regul Integr Comp Physiol
, vol.279
-
-
Balkan, B.1
Li, X.2
-
58
-
-
34748898831
-
Glucagon-like peptide-1 (GLP-1) receptors expressed on nerve terminals in the portal vein mediate the effects of endogenous GLP-1 on glucose tolerance in rats
-
Vahl TP, Tauchi M, Durler TS, Elfers EE, Fernandes TM, Bitner RD, Ellis KS, Woods SC, Seeley RJ, Herman JP, et al. Glucagon-like peptide-1 (GLP-1) receptors expressed on nerve terminals in the portal vein mediate the effects of endogenous GLP-1 on glucose tolerance in rats. Endocrinology 2007. 148:4965-4973.
-
(2007)
Endocrinology
, vol.148
, pp. 4965-4973
-
-
Vahl, T.P.1
Tauchi, M.2
Durler, T.S.3
Elfers, E.E.4
Fernandes, T.M.5
Bitner, R.D.6
Ellis, K.S.7
Woods, S.C.8
Seeley, R.J.9
Herman, J.P.10
-
59
-
-
55849125147
-
Role of central nervous system glucagon- like Peptide-1 receptors in enteric glucose sensing
-
Knauf C, Cani PD, Kim DH, Iglesias MA, Chabo C, Waget A, Colom A, Rastrelli S, Delzenne NM, Drucker DJ, et al. Role of central nervous system glucagon- like Peptide-1 receptors in enteric glucose sensing. Diabetes 2008. 57:2603-2612.
-
(2008)
Diabetes
, vol.57
, pp. 2603-2612
-
-
Knauf, C.1
Cani, P.D.2
Kim, D.H.3
Iglesias, M.A.4
Chabo, C.5
Waget, A.6
Colom, A.7
Rastrelli, S.8
Delzenne, N.M.9
Drucker, D.J.10
-
60
-
-
0021242737
-
Projection of the hepatic vagal nerve in the medulla oblongata
-
Adachi A. Projection of the hepatic vagal nerve in the medulla oblongata. J Auton Nerv Syst 1984. 10:287-293.
-
(1984)
J Auton Nerv Syst
, vol.10
, pp. 287-293
-
-
Adachi, A.1
-
61
-
-
0021367606
-
Convergence of hepatoportal glucose-sensitive afferent signals to glucose-sensitive units within the nucleus of the solitary tract
-
Adachi A, Shimizu N, Oomura Y, Kobashi M. Convergence of hepatoportal glucose-sensitive afferent signals to glucose-sensitive units within the nucleus of the solitary tract. Neurosci Lett 1984. 46:215-218.
-
(1984)
Neurosci Lett
, vol.46
, pp. 215-218
-
-
Adachi, A.1
Shimizu, N.2
Oomura, Y.3
Kobashi, M.4
-
62
-
-
77954102250
-
Hepatic-portal vein infusions of glucagon-like peptide-1 reduce meal size and increase c-Fos expression in the nucleus tractus solitarii, area postrema and central nucleus of the amygdala in rats
-
Baumgartner I, Pacheco-Lopez G, Ruttimann EB, Arnold M, Asarian L, Langhans W, Geary N, Hillebrand JJ. Hepatic-portal vein infusions of glucagon-like peptide-1 reduce meal size and increase c-Fos expression in the nucleus tractus solitarii, area postrema and central nucleus of the amygdala in rats. J Neuroendocrinol 2010. 22:557-563.
-
(2010)
J Neuroendocrinol
, vol.22
, pp. 557-563
-
-
Baumgartner, I.1
Pacheco-Lopez, G.2
Ruttimann, E.B.3
Arnold, M.4
Asarian, L.5
Langhans, W.6
Geary, N.7
Hillebrand, J.J.8
-
63
-
-
77953915094
-
Exenatide reduces food intake and activates the enteric nervous system of the gastrointestinal tract and the dorsal vagal complex of the hindbrain in the rat by a GLP-1 receptor
-
Washington MC, Raboin SJ, Thompson W, Larsen CJ, Sayegh AI. Exenatide reduces food intake and activates the enteric nervous system of the gastrointestinal tract and the dorsal vagal complex of the hindbrain in the rat by a GLP-1 receptor. Brain Res 2010. 1344:124-133.
-
(2010)
Brain Res
, vol.1344
, pp. 124-133
-
-
Washington, M.C.1
Raboin, S.J.2
Thompson, W.3
Larsen, C.J.4
Sayegh, A.I.5
-
64
-
-
0020530053
-
Functional correlations between lateral hypothalamic glucose-sensitive neurons and hepatic portal glucosesensitive units in rat
-
Shimizu N, Oomura Y, Novin D, Grijalva CV, Cooper PH. Functional correlations between lateral hypothalamic glucose-sensitive neurons and hepatic portal glucosesensitive units in rat. Brain Res 1983. 265:49-54.
-
(1983)
Brain Res
, vol.265
, pp. 49-54
-
-
Shimizu, N.1
Oomura, Y.2
Novin, D.3
Grijalva, C.V.4
Cooper, P.H.5
-
65
-
-
0033815547
-
Portal glucose infusion in the mouse induces hypoglycemia: Evidence that the hepatoportal glucose sensor stimulates glucose utilization
-
Burcelin R, Dolci W, Thorens B. Portal glucose infusion in the mouse induces hypoglycemia: evidence that the hepatoportal glucose sensor stimulates glucose utilization. Diabetes 2000. 49:1635-1642.
-
(2000)
Diabetes
, vol.49
, pp. 1635-1642
-
-
Burcelin, R.1
Dolci, W.2
Thorens, B.3
-
66
-
-
0038651914
-
GLUT4, AMP kinase, but not the insulin receptor, are required for hepatoportal glucose sensorstimulated muscle glucose utilization
-
Burcelin R, Crivelli V, Perrin C, Da Costa A, Mu J, Kahn BB, Birnbaum MJ, Kahn CR, Vollenweider P, Thorens B. GLUT4, AMP kinase, but not the insulin receptor, are required for hepatoportal glucose sensorstimulated muscle glucose utilization. J Clin Invest 2003. 111:1555-1562.
-
(2003)
J Clin Invest
, vol.111
, pp. 1555-1562
-
-
Burcelin, R.1
Crivelli, V.2
Perrin, C.3
da Costa, A.4
Mu, J.5
Kahn, B.B.6
Birnbaum, M.J.7
Kahn, C.R.8
Vollenweider, P.9
Thorens, B.10
-
67
-
-
0033810262
-
Glucose sensing by the hepatoportal sensor is GLUT2-dependent: In vivo analysis in GLUT2-null mice
-
Burcelin R, Dolci W, Thorens B. Glucose sensing by the hepatoportal sensor is GLUT2-dependent: in vivo analysis in GLUT2-null mice. Diabetes 2000. 49:1643-1648.
-
(2000)
Diabetes
, vol.49
, pp. 1643-1648
-
-
Burcelin, R.1
Dolci, W.2
Thorens, B.3
-
68
-
-
0029903111
-
Glucagonlike peptide I receptors in the subfornical organ and the area postrema are accessible to circulating glucagon-like peptide I
-
Orskov C, Poulsen SS, Moller M, Holst JJ. Glucagonlike peptide I receptors in the subfornical organ and the area postrema are accessible to circulating glucagon-like peptide I. Diabetes 1996. 45:832-835.
-
(1996)
Diabetes
, vol.45
, pp. 832-835
-
-
Orskov, C.1
Poulsen, S.S.2
Moller, M.3
Holst, J.J.4
-
69
-
-
0036307872
-
Glucagon-like peptide-1 receptor stimulation increases blood pressure and heart rate and activates autonomic regulatory neurons
-
Yamamoto H, Lee CE, Marcus JN, Williams TD, Overton JM, Lopez ME, Hollenberg AN, Baggio L, Saper CB, Drucker DJ, et al. Glucagon-like peptide-1 receptor stimulation increases blood pressure and heart rate and activates autonomic regulatory neurons. J Clin Invest 2002. 110:43-52.
-
(2002)
J Clin Invest
, vol.110
, pp. 43-52
-
-
Yamamoto, H.1
Lee, C.E.2
Marcus, J.N.3
Williams, T.D.4
Overton, J.M.5
Lopez, M.E.6
Hollenberg, A.N.7
Baggio, L.8
Saper, C.B.9
Drucker, D.J.10
-
70
-
-
31044456099
-
Brain glucagon-like peptide-1 increases insulin secretion and muscle insulin resistance to favor hepatic glycogen storage
-
Knauf C, Cani PD, Perrin C, Iglesias MA, Maury JF, Bernard E, Benhamed F, Gremeaux T, Drucker DJ, Kahn CR, et al. Brain glucagon-like peptide-1 increases insulin secretion and muscle insulin resistance to favor hepatic glycogen storage. J Clin Invest 2005. 115:3554-3563.
-
(2005)
J Clin Invest
, vol.115
, pp. 3554-3563
-
-
Knauf, C.1
Cani, P.D.2
Perrin, C.3
Iglesias, M.A.4
Maury, J.F.5
Bernard, E.6
Benhamed, F.7
Gremeaux, T.8
Drucker, D.J.9
Kahn, C.R.10
-
71
-
-
57149110807
-
What is known, new and controversial about GLP-1?
-
Minutes of the 1st European GLP-1 Club Meeting, Marseille, 28-29 May 2008
-
Burcelin R. What is known, new and controversial about GLP-1? Minutes of the 1st European GLP-1 Club Meeting, Marseille, 28-29 May 2008. Diabetes Metab 2008. 34:627-630.
-
(2008)
Diabetes Metab
, vol.34
, pp. 627-630
-
-
Burcelin, R.1
-
72
-
-
0026648961
-
Isolation and characterization of exendin-4, an exendin- 3 analogue, from Heloderma suspectum venom. Further evidence for an exendin receptor on dispersed acini from guinea pig pancreas
-
Eng J, Kleinman WA, Singh L, Singh G, Raufman JP. Isolation and characterization of exendin-4, an exendin- 3 analogue, from Heloderma suspectum venom. Further evidence for an exendin receptor on dispersed acini from guinea pig pancreas. J Biol Chem 1992. 267:7402-7405.
-
(1992)
J Biol Chem
, vol.267
, pp. 7402-7405
-
-
Eng, J.1
Kleinman, W.A.2
Singh, L.3
Singh, G.4
Raufman, J.P.5
-
73
-
-
0026795135
-
Truncated glucagon- like peptide-1 interacts with exendin receptors on dispersed acini from guinea pig pancreas. Identification of a mammalian analogue of the reptilian peptide exendin-4
-
Raufman JP, Singh L, Singh G, Eng J. Truncated glucagon- like peptide-1 interacts with exendin receptors on dispersed acini from guinea pig pancreas. Identification of a mammalian analogue of the reptilian peptide exendin-4. J Biol Chem 1992. 267:21432-21437.
-
(1992)
J Biol Chem
, vol.267
, pp. 21432-21437
-
-
Raufman, J.P.1
Singh, L.2
Singh, G.3
Eng, J.4
-
74
-
-
0027184119
-
Exendin-4 is a high potency agonist and truncated exendin-(9-39)-amide an antagonist at the glucagon-like peptide 1-(7-36)-amide receptor of insulinsecreting beta-cells
-
Goke R, Fehmann HC, Linn T, Schmidt H, Krause M, Eng J, Goke B. Exendin-4 is a high potency agonist and truncated exendin-(9-39)-amide an antagonist at the glucagon-like peptide 1-(7-36)-amide receptor of insulinsecreting beta-cells. J Biol Chem 1993. 268:19650-19655.
-
(1993)
J Biol Chem
, vol.268
, pp. 19650-19655
-
-
Goke, R.1
Fehmann, H.C.2
Linn, T.3
Schmidt, H.4
Krause, M.5
Eng, J.6
Goke, B.7
-
75
-
-
10244241840
-
Colocalization of glucagon-like peptide-1 (GLP-1) receptors, glucose transporter GLUT-2, and glucokinase mRNAs in rat hypothalamic cells: Evidence for a role of GLP-1 receptor agonists as an inhibitory signal for food and water in-take
-
Navarro M, Rodriquez de Fonseca F, Alvarez E, Chowen JA, Zueco JA, Gomez R, Eng J, Blazquez E. Colocalization of glucagon-like peptide-1 (GLP-1) receptors, glucose transporter GLUT-2, and glucokinase mRNAs in rat hypothalamic cells: evidence for a role of GLP-1 receptor agonists as an inhibitory signal for food and water in-take. J Neurochem 1996. 67:1982-1991.
-
(1996)
J Neurochem
, vol.67
, pp. 1982-1991
-
-
Navarro, M.1
de Fonseca, R.F.2
Alvarez, E.3
Chowen, J.A.4
Zueco, J.A.5
Gomez, R.6
Eng, J.7
Blazquez, E.8
-
76
-
-
0029958404
-
Glucose intolerance but normal satiety in mice with a null mutation in the glucagon-like peptide 1 receptor gene
-
Scrocchi LA, Brown TJ, MaClusky N, Brubaker PL, Auerbach AB, Joyner AL, Drucker DJ. Glucose intolerance but normal satiety in mice with a null mutation in the glucagon-like peptide 1 receptor gene. Nat Med 1996. 2:1254-1258.
-
(1996)
Nat Med
, vol.2
, pp. 1254-1258
-
-
Scrocchi, L.A.1
Brown, T.J.2
Maclusky, N.3
Brubaker, P.L.4
Auerbach, A.B.5
Joyner, A.L.6
Drucker, D.J.7
-
77
-
-
13344282056
-
A role for glucagon-like peptide-1 in the central regulation of feeding
-
Turton MD, O'Shea D, Gunn I, Beak SA, Edwards CM, Meeran K, Choi SJ, Taylor GM, Heath MM, Lambert PD, et al. A role for glucagon-like peptide-1 in the central regulation of feeding. Nature 1996. 379:69-72.
-
(1996)
Nature
, vol.379
, pp. 69-72
-
-
Turton, M.D.1
O'Shea, D.2
Gunn, I.3
Beak, S.A.4
Edwards, C.M.5
Meeran, K.6
Choi, S.J.7
Taylor, G.M.8
Heath, M.M.9
Lambert, P.D.10
-
78
-
-
0029859220
-
Central administration of GLP-1-(7-36) amide inhibits food and water intake in rats
-
Tang-Christensen M, Larsen PJ, Goke R, Fink-Jensen A, Jessop DS, Moller M, Sheikh SP. Central administration of GLP-1-(7-36) amide inhibits food and water intake in rats. Am J Physiol 1996. 271:R848-R856.
-
(1996)
Am J Physiol
, vol.271
-
-
Tang-Christensen, M.1
Larsen, P.J.2
Goke, R.3
Fink-Jensen, A.4
Jessop, D.S.5
Moller, M.6
Sheikh, S.P.7
-
79
-
-
0031891391
-
PVN infusion of GLP-1-(7- 36) amide suppresses feeding but does not induce aversion or alter locomotion in rats
-
McMahon LR, Wellman PJ. PVN infusion of GLP-1-(7- 36) amide suppresses feeding but does not induce aversion or alter locomotion in rats. Am J Physiol 1998. 274:R23-R29.
-
(1998)
Am J Physiol
, vol.274
-
-
McMahon, L.R.1
Wellman, P.J.2
-
80
-
-
0032940582
-
Repeated intracerebroventricular administration of glucagon-like peptide-1-(7-36) amide or exendin-(9-39) alters body weight in the rat
-
Meeran K, O'Shea D, Edwards CM, Turton MD, Heath MM, Gunn I, Abusnana S, Rossi M, Small CJ, et al. Repeated intracerebroventricular administration of glucagon-like peptide-1-(7-36) amide or exendin-(9-39) alters body weight in the rat. Endocrinology 1999. 140:244-250.
-
(1999)
Endocrinology
, vol.140
, pp. 244-250
-
-
Meeran, K.1
O'Shea, D.2
Edwards, C.M.3
Turton, M.D.4
Heath, M.M.5
Gunn, I.6
Abusnana, S.7
Rossi, M.8
Small, C.J.9
-
81
-
-
0032005005
-
Glucagon-like peptide 1 promotes satiety and suppresses energy intake in humans
-
Flint A, Raben A, Astrup A, Holst JJ. Glucagon-like peptide 1 promotes satiety and suppresses energy intake in humans. J Clin Invest 1998. 101:515-520.
-
(1998)
J Clin Invest
, vol.101
, pp. 515-520
-
-
Flint, A.1
Raben, A.2
Astrup, A.3
Holst, J.J.4
-
82
-
-
0032966882
-
Glucagon-like peptide-1 promotes satiety and reduces food intake in patients with diabetes mellitus type 2
-
Gutzwiller JP, Drewe J, Goke B, Schmidt H, Rohrer B, Lareida J, Beglinger C. Glucagon-like peptide-1 promotes satiety and reduces food intake in patients with diabetes mellitus type 2. Am J Physiol 1999. 276:R1541-R1544.
-
(1999)
Am J Physiol
, vol.276
-
-
Gutzwiller, J.P.1
Drewe, J.2
Goke, B.3
Schmidt, H.4
Rohrer, B.5
Lareida, J.6
Beglinger, C.7
-
83
-
-
0033021677
-
Energy intake and appetite are suppressed by glucagon-like peptide-1 (GLP-1) in obese men
-
Naslund E, Barkeling B, King N, Gutniak M, Blundell JE, Holst JJ, Rossner S, Hellstrom PM. Energy intake and appetite are suppressed by glucagon-like peptide-1 (GLP-1) in obese men. Int J Obes Relat Metab Disord 1999. 23:304-311.
-
(1999)
Int J Obes Relat Metab Disord
, vol.23
, pp. 304-311
-
-
Naslund, E.1
Barkeling, B.2
King, N.3
Gutniak, M.4
Blundell, J.E.5
Holst, J.J.6
Rossner, S.7
Hellstrom, P.M.8
-
84
-
-
0037066595
-
Glucagon-like peptide 1 as a regulator of food intake and body weight: Therapeutic perspectives
-
Meier JJ, Gallwitz B, Schmidt WE, Nauck MA. Glucagon-like peptide 1 as a regulator of food intake and body weight: therapeutic perspectives. Eur J Pharmacol 2002. 440:269-279.
-
(2002)
Eur J Pharmacol
, vol.440
, pp. 269-279
-
-
Meier, J.J.1
Gallwitz, B.2
Schmidt, W.E.3
Nauck, M.A.4
-
85
-
-
0030068620
-
Gastric emptying, glucose responses, and insulin secretion after a liquid test meal: Effects of exogenous glucagon-like peptide-1 (GLP-1)-(7-36) amide in type 2 (noninsulin-dependent) diabetic patients
-
Willms B, Werner J, Holst JJ, Orskov C, Creutzfeldt W, Nauck MA. Gastric emptying, glucose responses, and insulin secretion after a liquid test meal: effects of exogenous glucagon-like peptide-1 (GLP-1)-(7-36) amide in type 2 (noninsulin-dependent) diabetic patients. J Clin Endocrinol Metab 1996. 81:327-332.
-
(1996)
J Clin Endocrinol Metab
, vol.81
, pp. 327-332
-
-
Willms, B.1
Werner, J.2
Holst, J.J.3
Orskov, C.4
Creutzfeldt, W.5
Nauck, M.A.6
-
86
-
-
0032871230
-
GLP-1 slows solid gastric emptying and inhibits insulin, glucagon, and PYY release in humans
-
Naslund E, Bogefors J, Skogar S, Gryback P, Jacobsson H, Holst JJ, Hellstrom PM. GLP-1 slows solid gastric emptying and inhibits insulin, glucagon, and PYY release in humans. Am J Physiol 1999. 277:R910-R916.
-
(1999)
Am J Physiol
, vol.277
-
-
Naslund, E.1
Bogefors, J.2
Skogar, S.3
Gryback, P.4
Jacobsson, H.5
Holst, J.J.6
Hellstrom, P.M.7
-
87
-
-
17944365214
-
A meta-analysis of the effect of glucagon-like peptide-1 (7-36) amide on ad libitum energy intake in humans
-
Verdich C, Flint A, Gutzwiller JP, Naslund E, Beglinger C, Hellstrom PM, Long SJ, Morgan LM, Holst JJ, Astrup A. A meta-analysis of the effect of glucagon-like peptide-1 (7-36) amide on ad libitum energy intake in humans. J Clin Endocrinol Metab 2001. 86:4382-4389.
-
(2001)
J Clin Endocrinol Metab
, vol.86
, pp. 4382-4389
-
-
Verdich, C.1
Flint, A.2
Gutzwiller, J.P.3
Naslund, E.4
Beglinger, C.5
Hellstrom, P.M.6
Long, S.J.7
Morgan, L.M.8
Holst, J.J.9
Astrup, A.10
-
88
-
-
67649636449
-
Intrameal hepatic portal and intraperitoneal infusions of glucagon-like peptide-1 reduce spontaneous meal size in the rat via different mechanisms
-
Ruttimann EB, Arnold M, Hillebrand JJ, Geary N, Langhans W. Intrameal hepatic portal and intraperitoneal infusions of glucagon-like peptide-1 reduce spontaneous meal size in the rat via different mechanisms. Endocrinology 2009. 150:1174-1181.
-
(2009)
Endocrinology
, vol.150
, pp. 1174-1181
-
-
Ruttimann, E.B.1
Arnold, M.2
Hillebrand, J.J.3
Geary, N.4
Langhans, W.5
-
89
-
-
63849248275
-
Evidence that intestinal glucagon-like peptide-1 plays a physiological role in satiety
-
Williams DL, Baskin DG, Schwartz MW. Evidence that intestinal glucagon-like peptide-1 plays a physiological role in satiety. Endocrinology 2009. 150:1680-1687.
-
(2009)
Endocrinology
, vol.150
, pp. 1680-1687
-
-
Williams, D.L.1
Baskin, D.G.2
Schwartz, M.W.3
-
90
-
-
77955573674
-
Efficacy and safety of exenatide once weekly versus sitagliptin or pioglitazone as an adjunct to metformin for treatment of type 2 diabetes (DURATION-2): A randomized trial
-
Bergenstal RM, Wysham C, Macconell L, Malloy J, Walsh B, Yan P, Wilhelm K, Malone J, Porter LE. Efficacy and safety of exenatide once weekly versus sitagliptin or pioglitazone as an adjunct to metformin for treatment of type 2 diabetes (DURATION-2): a randomized trial. Lancet 2010. 376:431-439.
-
(2010)
Lancet
, vol.376
, pp. 431-439
-
-
Bergenstal, R.M.1
Wysham, C.2
Macconell, L.3
Malloy, J.4
Walsh, B.5
Yan, P.6
Wilhelm, K.7
Malone, J.8
Porter, L.E.9
-
91
-
-
77953859640
-
Once weekly exenatide compared with insulin glargine titrated to target in patients with type 2 diabetes (DURATION-3): An open-label randomized trial
-
Diamant M, Van Gaal L, Stranks S, Northrup J, Cao D, Taylor K, Trautmann M. Once weekly exenatide compared with insulin glargine titrated to target in patients with type 2 diabetes (DURATION-3): an open-label randomized trial. Lancet 2010. 375:2234-2243.
-
(2010)
Lancet
, vol.375
, pp. 2234-2243
-
-
Diamant, M.1
van Gaal, L.2
Stranks, S.3
Northrup, J.4
Cao, D.5
Taylor, K.6
Trautmann, M.7
-
92
-
-
0347360186
-
Pharmacology of exenatide (synthetic exendin-4): A potential therapeutic for improved glycemic control of type 2 diabetes
-
Nielsen LL, Young AA, Parkes DG. Pharmacology of exenatide (synthetic exendin-4): a potential therapeutic for improved glycemic control of type 2 diabetes. Regul Pept 2004. 117:77-88.
-
(2004)
Regul Pept
, vol.117
, pp. 77-88
-
-
Nielsen, L.L.1
Young, A.A.2
Parkes, D.G.3
-
93
-
-
50949094723
-
Arcuate glucagon-like peptide 1 receptors regulate glucose homeostasis but not food intake
-
Sandoval DA, Bagnol D, Woods SC, D'Alessio DA, Seeley RJ. Arcuate glucagon-like peptide 1 receptors regulate glucose homeostasis but not food intake. Diabetes 2008. 57:2046-2054.
-
(2008)
Diabetes
, vol.57
, pp. 2046-2054
-
-
Sandoval, D.A.1
Bagnol, D.2
Woods, S.C.3
D'alessio, D.A.4
Seeley, R.J.5
-
94
-
-
55049140818
-
Acute effects of glucagon-like peptide-1 on hypothalamic neuropeptide and AMP activated kinase expression in fasted rats
-
Seo S, Ju S, Chung H, Lee D, Park S. Acute effects of glucagon-like peptide-1 on hypothalamic neuropeptide and AMP activated kinase expression in fasted rats. Endocr J 2008. 55:867-874.
-
(2008)
Endocr J
, vol.55
, pp. 867-874
-
-
Seo, S.1
Ju, S.2
Chung, H.3
Lee, D.4
Park, S.5
-
95
-
-
0029119084
-
Insulin-mediated skeletal muscle vasodilation contributes to both insulin sensitivity and responsiveness in lean humans
-
Baron AD, Steinberg HO, Chaker H, Leaming R, Johnson A, Brechtel G. Insulin-mediated skeletal muscle vasodilation contributes to both insulin sensitivity and responsiveness in lean humans. J Clin Invest 1995. 96:786-792.
-
(1995)
J Clin Invest
, vol.96
, pp. 786-792
-
-
Baron, A.D.1
Steinberg, H.O.2
Chaker, H.3
Leaming, R.4
Johnson, A.5
Brechtel, G.6
-
96
-
-
0025954408
-
Mechanism of insulin resistance in insulin-dependent diabetes mellitus: A major role for reduced skeletal muscle blood flow
-
Baron AD, Laakso M, Brechtel G, Edelman SV. Mechanism of insulin resistance in insulin-dependent diabetes mellitus: a major role for reduced skeletal muscle blood flow. J Clin Endocrinol Metab 1991. 73:637-643.
-
(1991)
J Clin Endocrinol Metab
, vol.73
, pp. 637-643
-
-
Baron, A.D.1
Laakso, M.2
Brechtel, G.3
Edelman, S.V.4
-
97
-
-
0029977757
-
Obesity/insulin resistance is associated with endothelial dysfunction. Implications for the syndrome of insulin resistance
-
Steinberg HO, Chaker H, Leaming R, Johnson A, Brechtel G, Baron AD. Obesity/insulin resistance is associated with endothelial dysfunction. Implications for the syndrome of insulin resistance. J Clin Invest 1996. 97:2601-2610.
-
(1996)
J Clin Invest
, vol.97
, pp. 2601-2610
-
-
Steinberg, H.O.1
Chaker, H.2
Leaming, R.3
Johnson, A.4
Brechtel, G.5
Baron, A.D.6
-
98
-
-
0028030813
-
Insulin-mediated skeletal muscle vasodilation is nitric oxide dependent. A novel action of insulin to increase nitric oxide release
-
Steinberg HO, Brechtel G, Johnson A, Fineberg N, Baron AD. Insulin-mediated skeletal muscle vasodilation is nitric oxide dependent. A novel action of insulin to increase nitric oxide release. J Clin Invest 1994. 94:1172-1179.
-
(1994)
J Clin Invest
, vol.94
, pp. 1172-1179
-
-
Steinberg, H.O.1
Brechtel, G.2
Johnson, A.3
Fineberg, N.4
Baron, A.D.5
-
99
-
-
0032714917
-
Neural contribution to the effect of glucagon-like peptide-1-(7- 36) amide on arterial blood pressure in rats
-
Barragan JM, Eng J, Rodriguez R, Blazquez E. Neural contribution to the effect of glucagon-like peptide-1-(7- 36) amide on arterial blood pressure in rats. Am J Physiol 1999. 277:E784-E791.
-
(1999)
Am J Physiol
, vol.277
-
-
Barragan, J.M.1
Eng, J.2
Rodriguez, R.3
Blazquez, E.4
-
100
-
-
0842346377
-
Effects of intracerebroventricularly injected glucagon-like peptide-1 on cardiovascular parameters; role of central cholinergic system and vasopressin
-
Isbil-Buyukcoskun N, Gulec G. Effects of intracerebroventricularly injected glucagon-like peptide-1 on cardiovascular parameters; role of central cholinergic system and vasopressin. Regul Pept 2004. 118:33-38.
-
(2004)
Regul Pept
, vol.118
, pp. 33-38
-
-
Isbil-Buyukcoskun, N.1
Gulec, G.2
-
101
-
-
0030583731
-
Interactions of exendin-(9-39) with the effects of glucagon-like peptide-1-(7-36) amide and of exendin-4 on arterial blood pressure and heart rate in rats
-
Barragan JM, Rodriguez RE, Eng J, Blazquez E. Interactions of exendin-(9-39) with the effects of glucagon-like peptide-1-(7-36) amide and of exendin-4 on arterial blood pressure and heart rate in rats. Regul Pept 1996. 67:63-68.
-
(1996)
Regul Pept
, vol.67
, pp. 63-68
-
-
Barragan, J.M.1
Rodriguez, R.E.2
Eng, J.3
Blazquez, E.4
-
102
-
-
57649192347
-
Brain glucagon-like peptide-1 regulates arterial blood flow, heart rate, and insulin sensitivity
-
Cabou C, Campistron G, Marsollier N, Leloup C, Cruciani-Guglielmacci C, Penicaud L, Drucker DJ, Magnan C, Burcelin R. Brain glucagon-like peptide-1 regulates arterial blood flow, heart rate, and insulin sensitivity. Diabetes 2008. 57:2577-2587.
-
(2008)
Diabetes
, vol.57
, pp. 2577-2587
-
-
Cabou, C.1
Campistron, G.2
Marsollier, N.3
Leloup, C.4
Cruciani-Guglielmacci, C.5
Penicaud, L.6
Drucker, D.J.7
Magnan, C.8
Burcelin, R.9
-
103
-
-
54049143652
-
Effects of glucagon-like peptide-1, yohimbine, and nitrergic modulation on sympathetic and parasympathetic activity in humans
-
Bharucha AE, Charkoudian N, Andrews CN, Camilleri M, Sletten D, Zinsmeister AR, Low PA. Effects of glucagon-like peptide-1, yohimbine, and nitrergic modulation on sympathetic and parasympathetic activity in humans. Am J Physiol Regul Integr Comp Physiol 2008. 295:R874-R880.
-
(2008)
Am J Physiol Regul Integr Comp Physiol
, vol.295
-
-
Bharucha, A.E.1
Charkoudian, N.2
Andrews, C.N.3
Camilleri, M.4
Sletten, D.5
Zinsmeister, A.R.6
Low, P.A.7
-
104
-
-
0032976939
-
Continuous subcutaneous infusion of glucagon-like peptide 1 lowers plasma glucose and reduces appetite in type 2 diabetic patients
-
Toft-Nielsen MB, Madsbad S, Holst JJ. Continuous subcutaneous infusion of glucagon-like peptide 1 lowers plasma glucose and reduces appetite in type 2 diabetic patients. Diabetes Care 1999. 22:1137-1143.
-
(1999)
Diabetes Care
, vol.22
, pp. 1137-1143
-
-
Toft-Nielsen, M.B.1
Madsbad, S.2
Holst, J.J.3
-
105
-
-
76949099016
-
Effect of exenatide on heart rate and blood pressure in subjects with type 2 diabetes mellitus: A double-blind, placebo-controlled, randomized pilot study
-
Gill A, Hoogwerf BJ, Burger J, Bruce S, Macconell L, Yan P, Braun D, Giaconia J, Malone J. Effect of exenatide on heart rate and blood pressure in subjects with type 2 diabetes mellitus: a double-blind, placebo-controlled, randomized pilot study. Cardiovasc Diabetol 2010. 9:6.
-
(2010)
Cardiovasc Diabetol
, vol.9
, pp. 6
-
-
Gill, A.1
Hoogwerf, B.J.2
Burger, J.3
Bruce, S.4
Macconell, L.5
Yan, P.6
Braun, D.7
Giaconia, J.8
Malone, J.9
-
106
-
-
76749161358
-
Effects of exenatide on systolic blood pressure in subjects with type 2 diabetes
-
Okerson T, Yan P, Stonehouse A, Brodows R. Effects of exenatide on systolic blood pressure in subjects with type 2 diabetes. Am J Hypertens 2010. 23:334-339.
-
(2010)
Am J Hypertens
, vol.23
, pp. 334-339
-
-
Okerson, T.1
Yan, P.2
Stonehouse, A.3
Brodows, R.4
-
107
-
-
77749273703
-
Cardiovascular and metabolic effects of 48-h glucagon-like peptide-1 infusion in compensated chronic patients with heart failure
-
Halbirk M, Norrelund H, Moller N, Holst JJ, Schmitz O, Nielsen R, Nielsen-Kudsk JE, Nielsen SS, Nielsen TT, Eiskjaer H, et al. Cardiovascular and metabolic effects of 48-h glucagon-like peptide-1 infusion in compensated chronic patients with heart failure. Am J Physiol Heart Circ Physiol 2010. 298:H1096-H1102.
-
(2010)
Am J Physiol Heart Circ Physiol
, vol.298
-
-
Halbirk, M.1
Norrelund, H.2
Moller, N.3
Holst, J.J.4
Schmitz, O.5
Nielsen, R.6
Nielsen-Kudsk, J.E.7
Nielsen, S.S.8
Nielsen, T.T.9
Eiskjaer, H.10
-
108
-
-
77954738952
-
Impact of GLP-1 and GLP-1 receptor agonists on cardiovascular risk factors in type 2 diabetes
-
Verge D, Lopez X. Impact of GLP-1 and GLP-1 receptor agonists on cardiovascular risk factors in type 2 diabetes. Curr Diabetes Rev 2010. 6:191-200.
-
(2010)
Curr Diabetes Rev
, vol.6
, pp. 191-200
-
-
Verge, D.1
Lopez, X.2
-
109
-
-
65949097938
-
Direct control of peripheral lipid deposition by CNS GLP-1 receptor signaling is mediated by the sympathetic nervous system and blunted in diet-induced obesity
-
Nogueiras R, Perez-Tilve D, Veyrat-Durebex C, Morgan DA, Varela L, Haynes WG, Patterson JT, Disse E, Pfluger PT, Lopez M, et al. Direct control of peripheral lipid deposition by CNS GLP-1 receptor signaling is mediated by the sympathetic nervous system and blunted in diet-induced obesity. J Neurosci 2009. 29:5916-5925.
-
(2009)
J Neurosci
, vol.29
, pp. 5916-5925
-
-
Nogueiras, R.1
Perez-Tilve, D.2
Veyrat-Durebex, C.3
Morgan, D.A.4
Varela, L.5
Haynes, W.G.6
Patterson, J.T.7
Disse, E.8
Pfluger, P.T.9
Lopez, M.10
-
110
-
-
80052903104
-
Brain GLP-1 signaling regulates femoral artery blood flow and insulin sensitivity through hypothalamic PKC-delta
-
Cabou C, Vachoux C, Campistron G, Drucker DJ, Burcelin R. Brain GLP-1 signaling regulates femoral artery blood flow and insulin sensitivity through hypothalamic PKC-delta. Diabetes 2011. 60(9):2245-2256.
-
(2011)
Diabetes
, vol.60
, Issue.9
, pp. 2245-2256
-
-
Cabou, C.1
Vachoux, C.2
Campistron, G.3
Drucker, D.J.4
Burcelin, R.5
-
111
-
-
0028216874
-
The protein kinase C family for neuronal signaling
-
Tanaka C, Nishizuka Y. The protein kinase C family for neuronal signaling. Annu Rev Neurosci 1994. 17:551-567.
-
(1994)
Annu Rev Neurosci
, vol.17
, pp. 551-567
-
-
Tanaka, C.1
Nishizuka, Y.2
-
112
-
-
53249093993
-
Brain glucagon-like peptide 1 signaling controls the onset of high-fat diet-induced insulin resistance and reduces energy expenditure
-
Knauf C, Cani PD, Ait-Belgnaoui A, Benani A, Dray C, Cabou C, Colom A, Uldry M, Rastrelli S, Sabatier E, et al. Brain glucagon-like peptide 1 signaling controls the onset of high-fat diet-induced insulin resistance and reduces energy expenditure. Endocrinology 2008. 149:4768-4777.
-
(2008)
Endocrinology
, vol.149
, pp. 4768-4777
-
-
Knauf, C.1
Cani, P.D.2
Ait-Belgnaoui, A.3
Benani, A.4
Dray, C.5
Cabou, C.6
Colom, A.7
Uldry, M.8
Rastrelli, S.9
Sabatier, E.10
-
113
-
-
79960710589
-
Physiological and pharmacological mechanisms through which the DPP-4 inhibitor sitagliptin regulates glycemia in mice
-
Waget A, Cabou C, Masseboeuf M, Cattan P, Armanet M, Karaca M, Castel J, Garret C, Payros G, Maida A, et al. Physiological and pharmacological mechanisms through which the DPP-4 inhibitor sitagliptin regulates glycemia in mice. Endocrinology, 2011. 152(8):3018-3029.
-
(2011)
Endocrinology
, vol.152
, Issue.8
, pp. 3018-3029
-
-
Waget, A.1
Cabou, C.2
Masseboeuf, M.3
Cattan, P.4
Armanet, M.5
Karaca, M.6
Castel, J.7
Garret, C.8
Payros, G.9
Maida, A.10
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