-
2
-
-
84863707351
-
Cancer treatment and survivorship statistics, 2012
-
Siegel R, DeSantis C, Virgo K, Stein K, Mariotto A, Smith T, Cooper D, Gansler T, Lerro C, Fedewa S, et al: Cancer treatment and survivorship statistics, 2012. CA Cancer J Clin 62: 220-241, 2012.
-
(2012)
CA Cancer J Clin
, vol.62
, pp. 220-241
-
-
Siegel, R.1
DeSantis, C.2
Virgo, K.3
Stein, K.4
Mariotto, A.5
Smith, T.6
Cooper, D.7
Gansler, T.8
Lerro, C.9
Fedewa, S.10
-
3
-
-
79751489596
-
Molecular genetics of colorectal cancer
-
Fearon ER: Molecular genetics of colorectal cancer. Annu Rev Pathol 6: 479-507, 2011.
-
(2011)
Annu Rev Pathol
, vol.6
, pp. 479-507
-
-
Fearon, E.R.1
-
4
-
-
67949102053
-
Recent progress in the biology and physiology of sirtuins
-
Finkel T, Deng CX and Mostoslavsky R: Recent progress in the biology and physiology of sirtuins. Nature 460: 587-591, 2009.
-
(2009)
Nature
, vol.460
, pp. 587-591
-
-
Finkel, T.1
Deng, C.X.2
Mostoslavsky, R.3
-
5
-
-
84886904734
-
The emerging and diverse roles of sirtuins in cancer: A clinical perspective
-
Yuan H, Su L and Chen WY: The emerging and diverse roles of sirtuins in cancer: A clinical perspective. Onco Targets Ther 6: 1399-1416, 2013.
-
(2013)
Onco Targets Ther
, vol.6
, pp. 1399-1416
-
-
Yuan, H.1
Su, L.2
Chen, W.Y.3
-
6
-
-
27544434763
-
Tumor suppressor HIC1 directly regulates SIRT1 to modulate p53-dependent DNA-damage responses
-
Chen WY, Wang DH, Yen RC, Luo J, Gu W and Baylin SB: Tumor suppressor HIC1 directly regulates SIRT1 to modulate p53-dependent DNA-damage responses. Cell 123: 437-448, 2005.
-
(2005)
Cell
, vol.123
, pp. 437-448
-
-
Chen, W.Y.1
Wang, D.H.2
Yen, R.C.3
Luo, J.4
Gu, W.5
Baylin, S.B.6
-
7
-
-
12144290563
-
Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase
-
Brunet A, Sweeney LB, Sturgill JF, Chua KF, Greer PL, Lin Y, Tran H, Ross SE, Mostoslavsky R, Cohen HY, et al: Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase. Science 303: 2011-2015, 2004.
-
(2004)
Science
, vol.303
, pp. 2011-2015
-
-
Brunet, A.1
Sweeney, L.B.2
Sturgill, J.F.3
Chua, K.F.4
Greer, P.L.5
Lin, Y.6
Tran, H.7
Ross, S.E.8
Mostoslavsky, R.9
Cohen, H.Y.10
-
8
-
-
84903823510
-
Overexpression of sirt7 exhibits oncogenic property and serves as a prognostic factor in colorectal cancer
-
Yu H, Ye W, Wu J, Meng X, Liu RY, Ying X, Zhou Y, Wang H, Pan C and Huang W: Overexpression of sirt7 exhibits oncogenic property and serves as a prognostic factor in colorectal cancer. Clin Cancer Res 20: 3434-3445, 2014.
-
(2014)
Clin Cancer Res
, vol.20
, pp. 3434-3445
-
-
Yu, H.1
Ye, W.2
Wu, J.3
Meng, X.4
Liu, R.Y.5
Ying, X.6
Zhou, Y.7
Wang, H.8
Pan, C.9
Huang, W.10
-
9
-
-
84904812392
-
The sirtuin 3 expression profile is associated with pathological and clinical outcomes in colon cancer patients
-
Liu C, Huang Z, Jiang H and Shi F: The sirtuin 3 expression profile is associated with pathological and clinical outcomes in colon cancer patients. Biomed Res Int 2014: 871263, 2014.
-
(2014)
Biomed Res Int
, vol.2014
, pp. 871263
-
-
Liu, C.1
Huang, Z.2
Jiang, H.3
Shi, F.4
-
10
-
-
84870874690
-
The histone deacetylase SIRT6 is a tumor suppressor that controls cancer metabolism
-
Sebastián C, Zwaans BM, Silberman DM, Gymrek M, Goren A, Zhong L, Ram O, Truelove J, Guimaraes AR, Toiber D, et al: The histone deacetylase SIRT6 is a tumor suppressor that controls cancer metabolism. Cell 151: 1185-1199, 2012.
-
(2012)
Cell
, vol.151
, pp. 1185-1199
-
-
Sebastián, C.1
Zwaans, B.M.2
Silberman, D.M.3
Gymrek, M.4
Goren, A.5
Zhong, L.6
Ram, O.7
Truelove, J.8
Guimaraes, A.R.9
Toiber, D.10
-
11
-
-
67650563916
-
SirT1 is an inhibitor of proliferation and tumor formation in colon cancer
-
Kabra N, Li Z, Chen L, Li B, Zhang X, Wang C, Yeatman T, Coppola D and Chen J: SirT1 is an inhibitor of proliferation and tumor formation in colon cancer. J Biol Chem 284: 18210-18217, 2009.
-
(2009)
J Biol Chem
, vol.284
, pp. 18210-18217
-
-
Kabra, N.1
Li, Z.2
Chen, L.3
Li, B.4
Zhang, X.5
Wang, C.6
Yeatman, T.7
Coppola, D.8
Chen, J.9
-
12
-
-
0037291214
-
The human Sir2 ortholog, SIRT2, is an NAD+-dependent tubulin deacetylase
-
North BJ, Marshall BL, Borra MT, Denu JM and Verdin E: The human Sir2 ortholog, SIRT2, is an NAD+-dependent tubulin deacetylase. Mol Cell 11: 437-444, 2003.
-
(2003)
Mol Cell
, vol.11
, pp. 437-444
-
-
North, B.J.1
Marshall, B.L.2
Borra, M.T.3
Denu, J.M.4
Verdin, E.5
-
13
-
-
33646550204
-
SirT2 is a histone deacetylase with preference for histone H4 Lys 16 during mitosis
-
Vaquero A, Scher MB, Lee DH, Sutton A, Cheng HL, Alt FW, Serrano L, Sternglanz R and Reinberg D: SirT2 is a histone deacetylase with preference for histone H4 Lys 16 during mitosis. Genes Dev 20: 1256-1261, 2006.
-
(2006)
Genes Dev
, vol.20
, pp. 1256-1261
-
-
Vaquero, A.1
Scher, M.B.2
Lee, D.H.3
Sutton, A.4
Cheng, H.L.5
Alt, F.W.6
Serrano, L.7
Sternglanz, R.8
Reinberg, D.9
-
14
-
-
65549113750
-
CBP/p300-mediated acetylation of histone H3 on lysine 56
-
Das C, Lucia MS, Hansen KC and Tyler JK: CBP/p300-mediated acetylation of histone H3 on lysine 56. Nature 459: 113-117, 2009.
-
(2009)
Nature
, vol.459
, pp. 113-117
-
-
Das, C.1
Lucia, M.S.2
Hansen, K.C.3
Tyler, J.K.4
-
15
-
-
34547397081
-
SIRT2 regulates adipocyte differentiation through FoxO1 acetylation/deacetylation
-
Jing E, Gesta S and Kahn CR: SIRT2 regulates adipocyte differentiation through FoxO1 acetylation/deacetylation. Cell Metab 6: 105-114, 2007.
-
(2007)
Cell Metab
, vol.6
, pp. 105-114
-
-
Jing, E.1
Gesta, S.2
Kahn, C.R.3
-
16
-
-
39749143163
-
Sirt2 interacts with 14-3-3 beta/gamma and down-regulates the activity of p53
-
Jin YH, Kim YJ, Kim DW, Baek KH, Kang BY, Yeo CY and Lee KY: Sirt2 interacts with 14-3-3 beta/gamma and down-regulates the activity of p53. Biochem Biophys Res Commun 368: 690-695, 2008.
-
(2008)
Biochem Biophys Res Commun
, vol.368
, pp. 690-695
-
-
Jin, Y.H.1
Kim, Y.J.2
Kim, D.W.3
Baek, K.H.4
Kang, B.Y.5
Yeo, C.Y.6
Lee, K.Y.7
-
17
-
-
80054769188
-
SIRT2 maintains genome integrity and suppresses tumorigenesis through regulating APC/C activity
-
Kim HS, Vassilopoulos A, Wang RH, Lahusen T, Xiao Z, Xu X, Li C, Veenstra TD, Li B, Yu H, et al: SIRT2 maintains genome integrity and suppresses tumorigenesis through regulating APC/C activity. Cancer Cell 20: 487-499, 2011.
-
(2011)
Cancer Cell
, vol.20
, pp. 487-499
-
-
Kim, H.S.1
Vassilopoulos, A.2
Wang, R.H.3
Lahusen, T.4
Xiao, Z.5
Xu, X.6
Li, C.7
Veenstra, T.D.8
Li, B.9
Yu, H.10
-
18
-
-
33748316536
-
SIRT4 inhibits glutamate dehydrogenase and opposes the effects of calorie restriction in pancreatic beta cells
-
Haigis MC, Mostoslavsky R, Haigis KM, Fahie K, Christodoulou DC, Murphy AJ, Valenzuela DM, Yancopoulos GD, Karow M, Blander G, et al: SIRT4 inhibits glutamate dehydrogenase and opposes the effects of calorie restriction in pancreatic beta cells. Cell 126: 941-954, 2006.
-
(2006)
Cell
, vol.126
, pp. 941-954
-
-
Haigis, M.C.1
Mostoslavsky, R.2
Haigis, K.M.3
Fahie, K.4
Christodoulou, D.C.5
Murphy, A.J.6
Valenzuela, D.M.7
Yancopoulos, G.D.8
Karow, M.9
Blander, G.10
-
19
-
-
77957762687
-
SIRT4 regulates fatty acid oxidation and mitochondrial gene expression in liver and muscle cells
-
Nasrin N, Wu X, Fortier E, Feng Y, Bare' OC, Chen S, Ren X, Wu Z, Streeper RS and Bordone L: SIRT4 regulates fatty acid oxidation and mitochondrial gene expression in liver and muscle cells. J Biol Chem 285: 31995-32002, 2010.
-
(2010)
J Biol Chem
, vol.285
, pp. 31995-32002
-
-
Nasrin, N.1
Wu, X.2
Fortier, E.3
Feng, Y.4
Bare, O.C.5
Chen, S.6
Ren, X.7
Wu, Z.8
Streeper, R.S.9
Bordone, L.10
-
20
-
-
36349030394
-
Regulation of insulin secretion by SIRT4, a mitochondrial ADP-ribosyltransferase
-
Ahuja N, Schwer B, Carobbio S, Waltregny D, North BJ, Castronovo V, Maechler P and Verdin E: Regulation of insulin secretion by SIRT4, a mitochondrial ADP-ribosyltransferase. J Biol Chem 282: 33583-33592, 2007.
-
(2007)
J Biol Chem
, vol.282
, pp. 33583-33592
-
-
Ahuja, N.1
Schwer, B.2
Carobbio, S.3
Waltregny, D.4
North, B.J.5
Castronovo, V.6
Maechler, P.7
Verdin, E.8
-
21
-
-
84876359638
-
SIRT4 has tumorsuppressive activity and regulates the cellular metabolic response to DNA damage by inhibiting mitochondrial glutamine metabolism
-
Jeong SM, Xiao C, Finley LW, Lahusen T, Souza AL, Pierce K, Li YH, Wang X, Laurent G, German NJ, et al: SIRT4 has tumorsuppressive activity and regulates the cellular metabolic response to DNA damage by inhibiting mitochondrial glutamine metabolism. Cancer Cell 23: 450-463, 2013.
-
(2013)
Cancer Cell
, vol.23
, pp. 450-463
-
-
Jeong, S.M.1
Xiao, C.2
Finley, L.W.3
Lahusen, T.4
Souza, A.L.5
Pierce, K.6
Li, Y.H.7
Wang, X.8
Laurent, G.9
German, N.J.10
-
22
-
-
84877720366
-
The mTORC1 pathway stimulates glutamine metabolism and cell proliferation by repressing SIRT4
-
Csibi A, Fendt SM, Li C, Poulogiannis G, Choo AY, Chapski DJ, Jeong SM, Dempsey JM, Parkhitko A, Morrison T, et al: The mTORC1 pathway stimulates glutamine metabolism and cell proliferation by repressing SIRT4. Cell 153: 840-854, 2013.
-
(2013)
Cell
, vol.153
, pp. 840-854
-
-
Csibi, A.1
Fendt, S.M.2
Li, C.3
Poulogiannis, G.4
Choo, A.Y.5
Chapski, D.J.6
Jeong, S.M.7
Dempsey, J.M.8
Parkhitko, A.9
Morrison, T.10
-
23
-
-
84897565291
-
Lysine glutarylation is a protein posttranslational modification regulated by SIRT5
-
Tan M, Peng C, Anderson KA, Chhoy P, Xie Z, Dai L, Park J, Chen Y, Huang H, Zhang Y, et al: Lysine glutarylation is a protein posttranslational modification regulated by SIRT5. Cell Metab 19: 605-617, 2014.
-
(2014)
Cell Metab
, vol.19
, pp. 605-617
-
-
Tan, M.1
Peng, C.2
Anderson, K.A.3
Chhoy, P.4
Xie, Z.5
Dai, L.6
Park, J.7
Chen, Y.8
Huang, H.9
Zhang, Y.10
-
24
-
-
81055122671
-
Sirt5 is a NAD-dependent protein lysine demalonylase and desuccinylase
-
Du J, Zhou Y, Su X, Yu JJ, Khan S, Jiang H, Kim J, Woo J, Kim JH, Choi BH, et al: Sirt5 is a NAD-dependent protein lysine demalonylase and desuccinylase. Science 334: 806-809, 2011.
-
(2011)
Science
, vol.334
, pp. 806-809
-
-
Du, J.1
Zhou, Y.2
Su, X.3
Yu, J.J.4
Khan, S.5
Jiang, H.6
Kim, J.7
Woo, J.8
Kim, J.H.9
Choi, B.H.10
-
25
-
-
65249087389
-
SIRT5 deacetylates carbamoyl phosphate synthetase 1 and regulates the urea cycle
-
Nakagawa T, Lomb DJ, Haigis MC and Guarente L: SIRT5 deacetylates carbamoyl phosphate synthetase 1 and regulates the urea cycle. Cell 137: 560-570, 2009.
-
(2009)
Cell
, vol.137
, pp. 560-570
-
-
Nakagawa, T.1
Lomb, D.J.2
Haigis, M.C.3
Guarente, L.4
-
26
-
-
84928587149
-
SIRT5 facilitates cancer cell growth and drug resistance in non-small cell lung cancer
-
Lu W, Zuo Y, Feng Y and Zhang M: SIRT5 facilitates cancer cell growth and drug resistance in non-small cell lung cancer. Tumour Biol 35: 10699-10705, 2014.
-
(2014)
Tumour Biol
, vol.35
, pp. 10699-10705
-
-
Lu, W.1
Zuo, Y.2
Feng, Y.3
Zhang, M.4
-
27
-
-
84930519237
-
Sirtuin-4 (SIRT4) is downregulated and associated with some clinicopathological features in gastric adenocarcinoma
-
Huang G, Cui F, Yu F, Lu H, Zhang M, Tang H and Peng Z: Sirtuin-4 (SIRT4) is downregulated and associated with some clinicopathological features in gastric adenocarcinoma. Biomed Pharmacother 72: 135-139, 2015.
-
(2015)
Biomed Pharmacother
, vol.72
, pp. 135-139
-
-
Huang, G.1
Cui, F.2
Yu, F.3
Lu, H.4
Zhang, M.5
Tang, H.6
Peng, Z.7
-
28
-
-
84898011296
-
Sorting out functions of sirtuins in cancer
-
Roth M and Chen WY: Sorting out functions of sirtuins in cancer. Oncogene 33: 1609-1620, 2014.
-
(2014)
Oncogene
, vol.33
, pp. 1609-1620
-
-
Roth, M.1
Chen, W.Y.2
-
29
-
-
67650348173
-
Expression of DBC1 and SIRT1 is associated with poor prognosis of gastric carcinoma
-
Cha EJ, Noh SJ, Kwon KS, Kim CY, Park BH, Park HS, Lee H, Chung MJ, Kang MJ, Lee DG, et al: Expression of DBC1 and SIRT1 is associated with poor prognosis of gastric carcinoma. Clin Cancer Res 15: 4453-4459, 2009.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 4453-4459
-
-
Cha, E.J.1
Noh, S.J.2
Kwon, K.S.3
Kim, C.Y.4
Park, B.H.5
Park, H.S.6
Lee, H.7
Chung, M.J.8
Kang, M.J.9
Lee, D.G.10
-
30
-
-
36549044009
-
Function of the SIRT1 protein deacetylase in cancer
-
Stünkel W, Peh BK, Tan YC, Nayagam VM, Wang X, Salto-Tellez M, Ni B, Entzeroth M and Wood J: Function of the SIRT1 protein deacetylase in cancer. Biotechnol J 2: 1360-1368, 2007.
-
(2007)
Biotechnol J
, vol.2
, pp. 1360-1368
-
-
Stünkel, W.1
Peh, B.K.2
Tan, Y.C.3
Nayagam, V.M.4
Wang, X.5
Salto-Tellez, M.6
Ni, B.7
Entzeroth, M.8
Wood, J.9
-
31
-
-
34547100073
-
SIRT1 is significantly elevated in mouse and human prostate cancer
-
Huffman DM, Grizzle WE, Bamman MM, Kim JS, Eltoum IA, Elgavish A and Nagy TR: SIRT1 is significantly elevated in mouse and human prostate cancer. Cancer Res 67: 6612-6618, 2007.
-
(2007)
Cancer Res
, vol.67
, pp. 6612-6618
-
-
Huffman, D.M.1
Grizzle, W.E.2
Bamman, M.M.3
Kim, J.S.4
Eltoum, I.A.5
Elgavish, A.6
Nagy, T.R.7
-
32
-
-
34247570492
-
Strong expression of a longevity-related protein, SIRT1, in Bowen's disease
-
Hida Y, Kubo Y, Murao K and Arase S: Strong expression of a longevity-related protein, SIRT1, in Bowen's disease. Arch Dermatol Res 299: 103-106, 2007.
-
(2007)
Arch Dermatol Res
, vol.299
, pp. 103-106
-
-
Hida, Y.1
Kubo, Y.2
Murao, K.3
Arase, S.4
-
33
-
-
53149137486
-
Impaired DNA damage response, genome instability, and tumorigenesis in SIRT1 mutant mice
-
Wang RH, Sengupta K, Li C, Kim HS, Cao L, Xiao C, Kim S, Xu X, Zheng Y, Chilton B, et al: Impaired DNA damage response, genome instability, and tumorigenesis in SIRT1 mutant mice. Cancer Cell 14: 312-323, 2008.
-
(2008)
Cancer Cell
, vol.14
, pp. 312-323
-
-
Wang, R.H.1
Sengupta, K.2
Li, C.3
Kim, H.S.4
Cao, L.5
Xiao, C.6
Kim, S.7
Xu, X.8
Zheng, Y.9
Chilton, B.10
-
34
-
-
44849096876
-
The SIRT1 deacetylase suppresses intestinal tumorigenesis and colon cancer growth
-
Firestein R, Blander G, Michan S, Oberdoerffer P, Ogino S, Campbell J, Bhimavarapu A, Luikenhuis S, de Cabo R, Fuchs C, et al: The SIRT1 deacetylase suppresses intestinal tumorigenesis and colon cancer growth. PLoS One 3: e2020, 2008.
-
(2008)
PLoS One
, vol.3
, pp. e2020
-
-
Firestein, R.1
Blander, G.2
Michan, S.3
Oberdoerffer, P.4
Ogino, S.5
Campbell, J.6
Bhimavarapu, A.7
Luikenhuis, S.8
De Cabo, R.9
Fuchs, C.10
-
35
-
-
0041829415
-
Proteomics-based identification of differentially expressed genes in human gliomas: Down-regulation of SIRT2 gene
-
Hiratsuka M, Inoue T, Toda T, Kimura N, Shirayoshi Y, Kamitani H, Watanabe T, Ohama E, Tahimic CG, Kurimasa A, et al: Proteomics-based identification of differentially expressed genes in human gliomas: Down-regulation of SIRT2 gene. Biochem Biophys Res Commun 309: 558-566, 2003.
-
(2003)
Biochem Biophys Res Commun
, vol.309
, pp. 558-566
-
-
Hiratsuka, M.1
Inoue, T.2
Toda, T.3
Kimura, N.4
Shirayoshi, Y.5
Kamitani, H.6
Watanabe, T.7
Ohama, E.8
Tahimic, C.G.9
Kurimasa, A.10
-
36
-
-
84897744855
-
Mammalian SIRT2 inhibits keratin 19 expression and is a tumor suppressor in skin
-
Ming M, Qiang L, Zhao B and He YY: Mammalian SIRT2 inhibits keratin 19 expression and is a tumor suppressor in skin. Exp Dermatol 23: 207-209, 2014.
-
(2014)
Exp Dermatol
, vol.23
, pp. 207-209
-
-
Ming, M.1
Qiang, L.2
Zhao, B.3
He, Y.Y.4
-
37
-
-
84859447698
-
The role of sirtuin 2 activation by nicotinamide phosphoribosyltransferase in the aberrant proliferation and survival of myeloid leukemia cells
-
Dan L, Klimenkova O, Klimiankou M, Klusman JH, van den Heuvel-Eibrink MM, Reinhardt D, Welte K and Skokowa J: The role of sirtuin 2 activation by nicotinamide phosphoribosyltransferase in the aberrant proliferation and survival of myeloid leukemia cells. Haematologica 97: 551-559, 2012.
-
(2012)
Haematologica
, vol.97
, pp. 551-559
-
-
Dan, L.1
Klimenkova, O.2
Klimiankou, M.3
Klusman, J.H.4
Van Den Heuvel-Eibrink, M.M.5
Reinhardt, D.6
Welte, K.7
Skokowa, J.8
-
38
-
-
84870063661
-
Cortactin is associated with tumour progression and poor prognosis in prostate cancer and SIRT2 other than HADC6 may work as facilitator in situ
-
Hou H, Chen W, Zhao L, Zuo Q, Zhang G, Zhang X, Wang H, Gong H, Li X, Wang M, et al: Cortactin is associated with tumour progression and poor prognosis in prostate cancer and SIRT2 other than HADC6 may work as facilitator in situ. J Clin Pathol 65: 1088-1096, 2012.
-
(2012)
J Clin Pathol
, vol.65
, pp. 1088-1096
-
-
Hou, H.1
Chen, W.2
Zhao, L.3
Zuo, Q.4
Zhang, G.5
Zhang, X.6
Wang, H.7
Gong, H.8
Li, X.9
Wang, M.10
-
39
-
-
84894109588
-
SIRT4 suppresses tumor formation in genetic models of Myc-induced B cell lymphoma
-
Jeong SM, Lee A, Lee J and Haigis MC: SIRT4 suppresses tumor formation in genetic models of Myc-induced B cell lymphoma. J Biol Chem 289: 4135-4144, 2014.
-
(2014)
J Biol Chem
, vol.289
, pp. 4135-4144
-
-
Jeong, S.M.1
Lee, A.2
Lee, J.3
Haigis, M.C.4
-
40
-
-
79958787784
-
Sirtuin 1 is upregulated in a subset of hepatocellular carcinomas where it is essential for telomere maintenance and tumor cell growth
-
Chen J, Zhang B, Wong N, Lo AW, To KF, Chan AW, Ng MH, Ho CY, Cheng SH, Lai PB, et al: Sirtuin 1 is upregulated in a subset of hepatocellular carcinomas where it is essential for telomere maintenance and tumor cell growth. Cancer Res 71: 4138-4149, 2011.
-
(2011)
Cancer Res
, vol.71
, pp. 4138-4149
-
-
Chen, J.1
Zhang, B.2
Wong, N.3
Lo, A.W.4
To, K.F.5
Chan, A.W.6
Ng, M.H.7
Ho, C.Y.8
Cheng, S.H.9
Lai, P.B.10
-
41
-
-
84919933749
-
Sirtuin 4 is a lipoamidase regulating pyruvate dehydrogenase complex activity
-
Mathias RA, Greco TM, Oberstein A, Budayeva HG, Chakrabarti R, Rowland EA, Kang Y, Shenk T and Cristea IM: Sirtuin 4 is a lipoamidase regulating pyruvate dehydrogenase complex activity. Cell 159: 1615-1625, 2014.
-
(2014)
Cell
, vol.159
, pp. 1615-1625
-
-
Mathias, R.A.1
Greco, T.M.2
Oberstein, A.3
Budayeva, H.G.4
Chakrabarti, R.5
Rowland, E.A.6
Kang, Y.7
Shenk, T.8
Cristea, I.M.9
-
42
-
-
84875890762
-
Targeting cellular metabolism to improve cancer therapeutics
-
Zhao Y, Butler EB and Tan M: Targeting cellular metabolism to improve cancer therapeutics. Cell Death Dis 4: e532, 2013.
-
(2013)
Cell Death Dis
, vol.4
, pp. e532
-
-
Zhao, Y.1
Butler, E.B.2
Tan, M.3
-
44
-
-
39149111234
-
2-Deoxyglucose combined with wild-type p53 overexpression enhances cytotoxicity in human prostate cancer cells via oxidative stress
-
Ahmad IM, Abdalla MY, Aykin-Burns N, Simons AL, Oberley LW, Domann FE and Spitz DR: 2-Deoxyglucose combined with wild-type p53 overexpression enhances cytotoxicity in human prostate cancer cells via oxidative stress. Free Radic Biol Med 44: 826-834, 2008.
-
(2008)
Free Radic Biol Med
, vol.44
, pp. 826-834
-
-
Ahmad, I.M.1
Abdalla, M.Y.2
Aykin-Burns, N.3
Simons, A.L.4
Oberley, L.W.5
Domann, F.E.6
Spitz, D.R.7
-
45
-
-
84861975431
-
Metabolic reprogramming in cancer: Unraveling the role of glutamine in tumorigenesis
-
Daye D and Wellen KE: Metabolic reprogramming in cancer: Unraveling the role of glutamine in tumorigenesis. Semin Cell Dev Biol 23: 362-369, 2012.
-
(2012)
Semin Cell Dev Biol
, vol.23
, pp. 362-369
-
-
Daye, D.1
Wellen, K.E.2
-
46
-
-
77949967131
-
Targeting metabolic transformation for cancer therapy
-
Tennant DA, Durán RV and Gottlieb E: Targeting metabolic transformation for cancer therapy. Nat Rev Cancer 10: 267-277, 2010.
-
(2010)
Nat Rev Cancer
, vol.10
, pp. 267-277
-
-
Tennant, D.A.1
Durán, R.V.2
Gottlieb, E.3
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