Punicalagin attenuates palmitate-induced lipotoxicity in HepG2 cells by activating the Keap1-Nrf2 antioxidant defense system

Molecular Nutrition and Food Research

Volumn 60, Issue 5, 2016, Pages 1139-1149

  Yan, Chunhong ^a   Sun, Wenyan ^a   Wang, Xun ^a   Long, Jiangang ^a   Liu, Xuebo ^b   Feng, Zhihui ^a   Liu, Jiankang ^a  

^a XI'AN JIAOTONG UNIVERSITY   (China)

^b NORTHWEST A F UNIVERSITY   (China)

Author keywords

Hepatocyte; Lipotoxicity; Mitochondrial function; Nrf2; Punicalagin

Indexed keywords

ANTIOXIDANT; KEAP1 PROTEIN, HUMAN; KELCH LIKE ECH ASSOCIATED PROTEIN 1; NFE2L2 PROTEIN, HUMAN; PALMITIC ACID DERIVATIVE; PUNICALAGIN; REACTIVE OXYGEN METABOLITE; TANNIN; TRANSCRIPTION FACTOR NRF2;

APOPTOSIS; CELL SURVIVAL; CHEMISTRY; DRUG EFFECTS; GENETICS; HEP-G2 CELL LINE; HUMAN; LIPID METABOLISM; LIVER CELL; LYTHRACEAE; METABOLISM; MITOCHONDRION; SIGNAL TRANSDUCTION;

ANTIOXIDANTS; APOPTOSIS; CELL SURVIVAL; HEP G2 CELLS; HEPATOCYTES; HUMANS; HYDROLYZABLE TANNINS; KELCH-LIKE ECH-ASSOCIATED PROTEIN 1; LIPID METABOLISM; MITOCHONDRIA; NF-E2-RELATED FACTOR 2; PALMITATES; PUNICACEAE; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION;

EID: 84963860095     PISSN: 16134125     EISSN: 16134133     Source Type: Journal    
DOI: 10.1002/mnfr.201500490     Document Type: Article

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