BAX and BAK1 are dispensable for ABT-737- induced dissociation of the BCL2-BECN1 complex and autophagy

Autophagy

Volumn 11, Issue 3, 2015, Pages 452-459

  Pedro, Jose Manuel Bravo San ^a,b,c,d,e   Wei, Yongjie ^e   Sica, Valentina ^a,b,c,d,e   Maiuri, Maria Chiara ^a,b,c,d,e   Zou, Zhongju ^f   Kroemer, Guido ^a,b,c,e,g   Levine, Beth ^f  

^a CENTRE DE RECHERCHE DES CORDELIERS   (France)

^b INSERM   (France)

^c UNIVERSITÉ PARIS DESCARTES   (France)

^d INSTITUT GUSTAVE ROUSSY   (France)

^e Metabolomics and Cell Biology Platforms Gustave Roussy Cancer Campus   (France)

^f UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^g HÔPITAL EUROPÉEN GEORGES POMPIDOU   (France)

Author keywords

ABT 737; Apoptosis; Autophagy; BAK1; BAX; BCL2; BECN1 (Beclin 1)

Indexed keywords

4 [4 (4' CHLORO 2 BIPHENYLYLMETHYL) 1 PIPERAZINYL] N [4 [3 DIMETHYLAMINO 1 (PHENYLTHIOMETHYL)PROPYLAMINO] 3 NITROBENZENESULFONYL]BENZAMIDE; BAK1 PROTEIN; BECLIN 1; PROTEIN BAK; PROTEIN BAX; PROTEIN BCL 2; UNCLASSIFIED DRUG; ABT-737; APOPTOSIS REGULATORY PROTEIN; BAK1 PROTEIN, HUMAN; BAK1 PROTEIN, MOUSE; BAX PROTEIN (53-86); BAX PROTEIN, HUMAN; BAX PROTEIN, MOUSE; BCL2 PROTEIN, HUMAN; BCL2 PROTEIN, MOUSE; BECN1 PROTEIN, HUMAN; BECN1 PROTEIN, MOUSE; BIPHENYL DERIVATIVE; MEMBRANE PROTEIN; NITROPHENOL; ONCOPROTEIN; PEPTIDE FRAGMENT; PIPERAZINE DERIVATIVE; PROTEIN BINDING; SULFONAMIDE;

ANIMAL CELL; APOPTOSIS; ARTICLE; AUTOPHAGY; CELL CULTURE; CELL DEATH; CELL VIABILITY; DISSOCIATION; EMBRYO; ENVIRONMENTAL STRESS; FLOW CYTOMETRY; HCT116 CELL LINE; IMMUNOFLUORESCENCE; MOUSE; NONHUMAN; VIRUS PARTICLE; WESTERN BLOTTING; ANIMAL; CHEMISTRY; FIBROBLAST; FLUORESCENCE MICROSCOPY; HCT 116 CELL LINE; HUMAN; KNOCKOUT MOUSE; METABOLISM; TUMOR CELL LINE;

ANIMALS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; AUTOPHAGY; BCL-2 HOMOLOGOUS ANTAGONIST-KILLER PROTEIN; BCL-2-ASSOCIATED X PROTEIN; BECLIN-1; BIPHENYL COMPOUNDS; CELL LINE, TUMOR; FIBROBLASTS; FLOW CYTOMETRY; HCT116 CELLS; HUMANS; MEMBRANE PROTEINS; MICE; MICE, KNOCKOUT; MICROSCOPY, FLUORESCENCE; NITROPHENOLS; PEPTIDE FRAGMENTS; PIPERAZINES; PROTEIN BINDING; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; SULFONAMIDES;

EID: 84939866355     PISSN: 15548627     EISSN: 15548635     Source Type: Journal    
DOI: 10.1080/15548627.2015.1017191     Document Type: Article

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