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Volumn 8, Issue 4, 2013, Pages

Drug Screening for Autophagy Inhibitors Based on the Dissociation of Beclin1-Bcl2 Complex Using BiFC Technique and Mechanism of Eugenol on Anti-Influenza A Virus Activity

Author keywords

[No Author keywords available]

Indexed keywords

BECLIN 1; EUGENOL; HETERODIMER; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN BCL 2;

EID: 84876175515     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0061026     Document Type: Article
Times cited : (111)

References (45)
  • 1
    • 84866106043 scopus 로고    scopus 로고
    • Exploring the mechanism of zanamivir resistance in a neuraminidase mutant: a molecular dynamics study
    • Han N, Liu X, Mu Y, (2012) Exploring the mechanism of zanamivir resistance in a neuraminidase mutant: a molecular dynamics study. PLoS One 7: e44057.
    • (2012) PLoS One , vol.7
    • Han, N.1    Liu, X.2    Mu, Y.3
  • 2
    • 84856078603 scopus 로고    scopus 로고
    • Efficacy of combined therapy with amantadine, oseltamivir, and ribavirin in vivo against susceptible and amantadine-resistant influenza A viruses
    • Nguyen JT, Smee DF, Barnard DL, Julander JG, Gross M, et al. (2012) Efficacy of combined therapy with amantadine, oseltamivir, and ribavirin in vivo against susceptible and amantadine-resistant influenza A viruses. PLoS One 7: e31006.
    • (2012) PLoS One , vol.7
    • Nguyen, J.T.1    Smee, D.F.2    Barnard, D.L.3    Julander, J.G.4    Gross, M.5
  • 3
    • 79959614025 scopus 로고    scopus 로고
    • Rapid detection of the H275Y oseltamivir resistance mutation in influenza A/H1N1 2009 by single base pair RT-PCR and high-resolution melting
    • Tong SY, Dakh F, Hurt AC, Deng YM, Freeman K, et al. (2011) Rapid detection of the H275Y oseltamivir resistance mutation in influenza A/H1N1 2009 by single base pair RT-PCR and high-resolution melting. PLoS One 6: e21446.
    • (2011) PLoS One , vol.6
    • Tong, S.Y.1    Dakh, F.2    Hurt, A.C.3    Deng, Y.M.4    Freeman, K.5
  • 4
    • 72649105081 scopus 로고    scopus 로고
    • Matrix Protein 2 of Influenza A Virus Blocks Autophagosome Fusion with Lysosomes
    • Gannage M, Dormann D, Albrecht R, Dengjel J, Torossi T, et al. (2009) Matrix Protein 2 of Influenza A Virus Blocks Autophagosome Fusion with Lysosomes. Cell Host Microbe 6: 367-380.
    • (2009) Cell Host Microbe , vol.6 , pp. 367-380
    • Gannage, M.1    Dormann, D.2    Albrecht, R.3    Dengjel, J.4    Torossi, T.5
  • 5
    • 84855293818 scopus 로고    scopus 로고
    • IRGM Is a Common Target of RNA Viruses that Subvert the Autophagy Network
    • e1002422-Article No.: e1002422
    • Gregoire IP, Richetta C, Meyniel-Schicklin L, Borel S, Pradezynski F, et al. (2011) IRGM Is a Common Target of RNA Viruses that Subvert the Autophagy Network. PLoS Pathog 7: e1002422-Article No.: e1002422.
    • (2011) PLoS Pathog , vol.7
    • Gregoire, I.P.1    Richetta, C.2    Meyniel-Schicklin, L.3    Borel, S.4    Pradezynski, F.5
  • 6
    • 65249090334 scopus 로고    scopus 로고
    • Autophagy is involved in influenza A virus replication
    • Zhou Z, Jiang X, Liu D, Fan Z, Hu X, et al. (2009) Autophagy is involved in influenza A virus replication. Autophagy 5: 321-328.
    • (2009) Autophagy , vol.5 , pp. 321-328
    • Zhou, Z.1    Jiang, X.2    Liu, D.3    Fan, Z.4    Hu, X.5
  • 7
    • 84857460034 scopus 로고    scopus 로고
    • Inhibition of Autophagy Ameliorates Acute Lung Injury Caused by Avian Influenza A H5N1 Infection
    • Sun Y, Li C, Shu Y, Ju X, Zou Z, et al. (2012) Inhibition of Autophagy Ameliorates Acute Lung Injury Caused by Avian Influenza A H5N1 Infection. Sci Signal 5: ra16.
    • (2012) Sci Signal , vol.5
    • Sun, Y.1    Li, C.2    Shu, Y.3    Ju, X.4    Zou, Z.5
  • 8
    • 82455212854 scopus 로고    scopus 로고
    • Avian influenza A virus H5N1 causes autophagy-mediated cell death through suppression of mTOR signaling
    • Ma J, Sun Q, Mi R, Zhang H, (2011) Avian influenza A virus H5N1 causes autophagy-mediated cell death through suppression of mTOR signaling. J Genet Genomics 38: 533-537.
    • (2011) J Genet Genomics , vol.38 , pp. 533-537
    • Ma, J.1    Sun, Q.2    Mi, R.3    Zhang, H.4
  • 9
    • 0345167800 scopus 로고    scopus 로고
    • TSC2 mediates cellular energy response to control cell growth and survival
    • Inoki K, Zhu T, Guan KL, (2003) TSC2 mediates cellular energy response to control cell growth and survival. Cell 115: 577-590.
    • (2003) Cell , vol.115 , pp. 577-590
    • Inoki, K.1    Zhu, T.2    Guan, K.L.3
  • 10
    • 79960800953 scopus 로고    scopus 로고
    • Beclin-1 targeting for viral immune escape
    • Munz C, (2011) Beclin-1 targeting for viral immune escape. Viruses 3: 1166-1178.
    • (2011) Viruses , vol.3 , pp. 1166-1178
    • Munz, C.1
  • 11
    • 84862023791 scopus 로고    scopus 로고
    • Imperfect interface of Beclin1 coiled-coil domain regulates homodimer and heterodimer formation with Atg14L and UVRAG
    • Li X, He L, Che KH, Funderburk SF, Pan L, et al. (2012) Imperfect interface of Beclin1 coiled-coil domain regulates homodimer and heterodimer formation with Atg14L and UVRAG. Nat Commun 3: 662.
    • (2012) Nat Commun , vol.3 , pp. 662
    • Li, X.1    He, L.2    Che, K.H.3    Funderburk, S.F.4    Pan, L.5
  • 12
    • 79952628267 scopus 로고    scopus 로고
    • The Beclin 1 network regulates autophagy and apoptosis
    • Kang R, Zeh HJ, Lotze MT, Tang D, (2011) The Beclin 1 network regulates autophagy and apoptosis. Cell Death Differ 18: 571-580.
    • (2011) Cell Death Differ , vol.18 , pp. 571-580
    • Kang, R.1    Zeh, H.J.2    Lotze, M.T.3    Tang, D.4
  • 13
    • 68149139456 scopus 로고    scopus 로고
    • The autophagy effector Beclin 1: a novel BH3-only protein
    • Sinha S, Levine B, (2008) The autophagy effector Beclin 1: a novel BH3-only protein. Oncogene 27Suppl 1: S137-148.
    • (2008) Oncogene , vol.27
    • Sinha, S.1    Levine, B.2
  • 14
    • 77957680501 scopus 로고    scopus 로고
    • Traf6 and A20 differentially regulate TLR4-induced autophagy by affecting the ubiquitination of Beclin 1
    • Shi CS, Kehrl JH, (2010) Traf6 and A20 differentially regulate TLR4-induced autophagy by affecting the ubiquitination of Beclin 1. Autophagy 6: 986-987.
    • (2010) Autophagy , vol.6 , pp. 986-987
    • Shi, C.S.1    Kehrl, J.H.2
  • 17
    • 84857305639 scopus 로고    scopus 로고
    • Direct molecular interactions between Beclin 1 and the canonical NFkappaB activation pathway
    • Niso-Santano M, Criollo A, Malik SA, Michaud M, Morselli E, et al. (2012) Direct molecular interactions between Beclin 1 and the canonical NFkappaB activation pathway. Autophagy 8.
    • (2012) Autophagy , vol.8
    • Niso-Santano, M.1    Criollo, A.2    Malik, S.A.3    Michaud, M.4    Morselli, E.5
  • 18
    • 80053139511 scopus 로고    scopus 로고
    • Pepstatin A alters host cell autophagic machinery and leads to a decrease in influenza A virus production
    • Matarrese P, Nencioni L, Checconi P, Ciarlo L, Gambardella L, et al. (2011) Pepstatin A alters host cell autophagic machinery and leads to a decrease in influenza A virus production. J Cell Physiol 226: 3368-3377.
    • (2011) J Cell Physiol , vol.226 , pp. 3368-3377
    • Matarrese, P.1    Nencioni, L.2    Checconi, P.3    Ciarlo, L.4    Gambardella, L.5
  • 19
    • 84861808686 scopus 로고    scopus 로고
    • High-Throughput Screening for AntiInfluenza A Virus Drugs and Study of the Mechanism of Procyanidin on Influenza A VirusInduced Autophagy
    • DOI: 10.1177/1087057111435236
    • Dai J, Wang G, Li W, Zhang L, Yang J, et al. (2012) High-Throughput Screening for AntiInfluenza A Virus Drugs and Study of the Mechanism of Procyanidin on Influenza A VirusInduced Autophagy. J Biomol Screen DOI: 10.1177/1087057111435236.
    • (2012) J Biomol Screen
    • Dai, J.1    Wang, G.2    Li, W.3    Zhang, L.4    Yang, J.5
  • 20
    • 34247186472 scopus 로고    scopus 로고
    • Reactive oxygen species are essential for autophagy and specifically regulate the activity of Atg4
    • Scherz-Shouval R, Shvets E, Fass E, Shorer H, Gil L, et al. (2007) Reactive oxygen species are essential for autophagy and specifically regulate the activity of Atg4. Embo J 26: 1749-1760.
    • (2007) Embo J , vol.26 , pp. 1749-1760
    • Scherz-Shouval, R.1    Shvets, E.2    Fass, E.3    Shorer, H.4    Gil, L.5
  • 21
    • 77957652556 scopus 로고    scopus 로고
    • Anti-neoplastic activity of the cytosolic FoxO1 results from autophagic cell death
    • Zhao Y, Wang L, Yang J, Zhang P, Ma K, et al. (2010) Anti-neoplastic activity of the cytosolic FoxO1 results from autophagic cell death. Autophagy 6: 988-990.
    • (2010) Autophagy , vol.6 , pp. 988-990
    • Zhao, Y.1    Wang, L.2    Yang, J.3    Zhang, P.4    Ma, K.5
  • 22
    • 84862176440 scopus 로고    scopus 로고
    • ER-bound protein tyrosine phosphatase PTP1B interacts with Src at the plasma membrane/substrate interface
    • Monteleone MC, Gonzalez Wusener AE, Burdisso JE, Conde C, Caceres A, et al. (2012) ER-bound protein tyrosine phosphatase PTP1B interacts with Src at the plasma membrane/substrate interface. PLoS One 7: e38948.
    • (2012) PLoS One , vol.7
    • Monteleone, M.C.1    Gonzalez Wusener, A.E.2    Burdisso, J.E.3    Conde, C.4    Caceres, A.5
  • 23
    • 0036241055 scopus 로고    scopus 로고
    • Visualization of interactions among bZIP and Rel family proteins in living cells using bimolecular fluorescence complementation
    • Hu CD, Chinenov Y, Kerppola TK, (2002) Visualization of interactions among bZIP and Rel family proteins in living cells using bimolecular fluorescence complementation. Mol Cell 9: 789-798.
    • (2002) Mol Cell , vol.9 , pp. 789-798
    • Hu, C.D.1    Chinenov, Y.2    Kerppola, T.K.3
  • 24
  • 25
    • 83655190818 scopus 로고    scopus 로고
    • HMGB1 regulates autophagy through increasing transcriptional activities of JNK and ERK in human myeloid leukemia cells
    • Zhao M, Yang M, Yang L, Yu Y, Xie M, et al. (2011) HMGB1 regulates autophagy through increasing transcriptional activities of JNK and ERK in human myeloid leukemia cells. BMB Rep 44: 601-606.
    • (2011) BMB Rep , vol.44 , pp. 601-606
    • Zhao, M.1    Yang, M.2    Yang, L.3    Yu, Y.4    Xie, M.5
  • 26
    • 84855779811 scopus 로고    scopus 로고
    • Suppressing production of reactive oxygen species (ROS) for influenza A virus therapy
    • Vlahos R, Stambas J, Selemidis S, (2012) Suppressing production of reactive oxygen species (ROS) for influenza A virus therapy. Trends Pharmacol Sci 33: 3-8.
    • (2012) Trends Pharmacol Sci , vol.33 , pp. 3-8
    • Vlahos, R.1    Stambas, J.2    Selemidis, S.3
  • 27
    • 64549084052 scopus 로고    scopus 로고
    • Upregulation of Beclin-1 expression and phosphorylation of Bcl-2 and p53 are involved in the JNK-mediated autophagic cell death
    • Park KJ, Lee SH, Lee CH, Jang JY, Chung J, et al. (2009) Upregulation of Beclin-1 expression and phosphorylation of Bcl-2 and p53 are involved in the JNK-mediated autophagic cell death. Biochem Biophys Res Commun 382: 726-729.
    • (2009) Biochem Biophys Res Commun , vol.382 , pp. 726-729
    • Park, K.J.1    Lee, S.H.2    Lee, C.H.3    Jang, J.Y.4    Chung, J.5
  • 28
    • 70450221927 scopus 로고    scopus 로고
    • N-acetyl-L-cysteine (NAC) inhibits virus replication and expression of pro-inflammatory molecules in A549 cells infected with highly pathogenic H5N1 influenza A virus
    • Geiler J, Michaelis M, Naczk P, Leutz A, Langer K, et al. (2010) N-acetyl-L-cysteine (NAC) inhibits virus replication and expression of pro-inflammatory molecules in A549 cells infected with highly pathogenic H5N1 influenza A virus. Biochem Pharmacol 79: 413-420.
    • (2010) Biochem Pharmacol , vol.79 , pp. 413-420
    • Geiler, J.1    Michaelis, M.2    Naczk, P.3    Leutz, A.4    Langer, K.5
  • 29
    • 59149090850 scopus 로고    scopus 로고
    • Role of JNK1-dependent Bcl-2 phosphorylation in ceramide-induced macroautophagy
    • Pattingre S, Bauvy C, Carpentier S, Levade T, Levine B, et al. (2009) Role of JNK1-dependent Bcl-2 phosphorylation in ceramide-induced macroautophagy. J Biol Chem 284: 2719-2728.
    • (2009) J Biol Chem , vol.284 , pp. 2719-2728
    • Pattingre, S.1    Bauvy, C.2    Carpentier, S.3    Levade, T.4    Levine, B.5
  • 31
    • 80051777105 scopus 로고    scopus 로고
    • Eugenolol and glyceryl-isoeugenol suppress LPS-induced iNOS expression by down-regulating NF-kappaB AND AP-1 through inhibition of MAPKS and AKT/IkappaBalpha signaling pathways in macrophages
    • Yeh JL, Hsu JH, Hong YS, Wu JR, Liang JC,et al. Eugenolol and glyceryl-isoeugenol suppress LPS-induced iNOS expression by down-regulating NF-kappaB AND AP-1 through inhibition of MAPKS and AKT/IkappaBalpha signaling pathways in macrophages. Int J Immunopathol Pharmacol 24: 345-356.
    • Int J Immunopathol Pharmacol , vol.24 , pp. 345-356
    • Yeh, J.L.1    Hsu, J.H.2    Hong, Y.S.3    Wu, J.R.4    Liang, J.C.5
  • 32
    • 60149098492 scopus 로고    scopus 로고
    • The pivotal role of c-Jun NH2-terminal kinase-mediated Beclin 1 expression during anticancer agents-induced autophagy in cancer cells
    • Li DD, Wang LL, Deng R, Tang J, Shen Y, et al. (2009) The pivotal role of c-Jun NH2-terminal kinase-mediated Beclin 1 expression during anticancer agents-induced autophagy in cancer cells. Oncogene 28: 886-898.
    • (2009) Oncogene , vol.28 , pp. 886-898
    • Li, D.D.1    Wang, L.L.2    Deng, R.3    Tang, J.4    Shen, Y.5
  • 33
    • 80053303830 scopus 로고    scopus 로고
    • Autophagy and cytokines
    • Harris J, (2011) Autophagy and cytokines. Cytokine 56: 140-144.
    • (2011) Cytokine , vol.56 , pp. 140-144
    • Harris, J.1
  • 34
    • 78650606465 scopus 로고    scopus 로고
    • High-throughput identification of compounds targeting influenza RNA-dependent RNA polymerase activity
    • Su CY, Cheng TJ, Lin MI, Wang SY, Huang WI, et al. (2010) High-throughput identification of compounds targeting influenza RNA-dependent RNA polymerase activity. Proc Natl Acad Sci U S A 107: 19151-19156.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 19151-19156
    • Su, C.Y.1    Cheng, T.J.2    Lin, M.I.3    Wang, S.Y.4    Huang, W.I.5
  • 35
    • 21944446960 scopus 로고    scopus 로고
    • Drug screening for influenza neuraminidase inhibitors
    • Liu A, Cao H, Du G, (2005) Drug screening for influenza neuraminidase inhibitors. Sci China C Life Sci 48: 1-5.
    • (2005) Sci China C Life Sci , vol.48 , pp. 1-5
    • Liu, A.1    Cao, H.2    Du, G.3
  • 36
    • 77649295601 scopus 로고    scopus 로고
    • Pyrazole compound BPR1P0034 with potent and selective anti-influenza virus activity
    • Shih SR, Chu TY, Reddy GR, Tseng SN, Chen HL, et al. (2010) Pyrazole compound BPR1P0034 with potent and selective anti-influenza virus activity. J Biomed Sci 17: 13.
    • (2010) J Biomed Sci , vol.17 , pp. 13
    • Shih, S.R.1    Chu, T.Y.2    Reddy, G.R.3    Tseng, S.N.4    Chen, H.L.5
  • 37
    • 78951486960 scopus 로고    scopus 로고
    • Discovery of novel benzoquinazolinones and thiazoloimidazoles, inhibitors of influenza H5N1 and H1N1 viruses, from a cell-based high-throughput screen
    • Maddry JA, Chen X, Jonsson CB, Ananthan S, Hobrath J, et al. (2011) Discovery of novel benzoquinazolinones and thiazoloimidazoles, inhibitors of influenza H5N1 and H1N1 viruses, from a cell-based high-throughput screen. J Biomol Screen 16: 73-81.
    • (2011) J Biomol Screen , vol.16 , pp. 73-81
    • Maddry, J.A.1    Chen, X.2    Jonsson, C.B.3    Ananthan, S.4    Hobrath, J.5
  • 39
    • 80055073333 scopus 로고    scopus 로고
    • The host interactome of influenza virus presents new potential targets for antiviral drugs
    • Shaw ML, (2011) The host interactome of influenza virus presents new potential targets for antiviral drugs. Rev Med Virol 21: 358-369.
    • (2011) Rev Med Virol , vol.21 , pp. 358-369
    • Shaw, M.L.1
  • 40
    • 75149173978 scopus 로고    scopus 로고
    • Targeting Beclin 1 for viral subversion of macroautophagy
    • Gannage M, Ramer PC, Munz C, (2010) Targeting Beclin 1 for viral subversion of macroautophagy. Autophagy 6: 166-167.
    • (2010) Autophagy , vol.6 , pp. 166-167
    • Gannage, M.1    Ramer, P.C.2    Munz, C.3
  • 41
    • 79956126271 scopus 로고    scopus 로고
    • Oxidative stress stimulates autophagic flux during ischemia/reperfusion
    • Hariharan N, Zhai P, Sadoshima J, (2011) Oxidative stress stimulates autophagic flux during ischemia/reperfusion. Antioxid Redox Sign 14: 2179-2190.
    • (2011) Antioxid Redox Sign , vol.14 , pp. 2179-2190
    • Hariharan, N.1    Zhai, P.2    Sadoshima, J.3
  • 42
    • 69449092228 scopus 로고    scopus 로고
    • p65/RelA binds and activates the beclin 1 promoter
    • Copetti T, Demarchi F, Schneider C, (2009) p65/RelA binds and activates the beclin 1 promoter. Autophagy 5: 858-859.
    • (2009) Autophagy , vol.5 , pp. 858-859
    • Copetti, T.1    Demarchi, F.2    Schneider, C.3
  • 43
    • 61349195982 scopus 로고    scopus 로고
    • Influence of borneol on primary mice oral fibroblasts: a penetration enhancer may be used in oral submucous fibrosis
    • Dai JP, Chen J, Bei YF, Han BX, Wang S, (2009) Influence of borneol on primary mice oral fibroblasts: a penetration enhancer may be used in oral submucous fibrosis. J Oral Pathol Med 38: 276-281.
    • (2009) J Oral Pathol Med , vol.38 , pp. 276-281
    • Dai, J.P.1    Chen, J.2    Bei, Y.F.3    Han, B.X.4    Wang, S.5
  • 44
    • 53749106185 scopus 로고    scopus 로고
    • NF-kappaB signaling differentially regulates influenza virus RNA synthesis
    • Kumar N, Xin ZT, Liang Y, Ly H, Liang Y, (2008) NF-kappaB signaling differentially regulates influenza virus RNA synthesis. J Virol 82: 9880-9889.
    • (2008) J Virol , vol.82 , pp. 9880-9889
    • Kumar, N.1    Xin, Z.T.2    Liang, Y.3    Ly, H.4    Liang, Y.5
  • 45
    • 58149344941 scopus 로고    scopus 로고
    • Antiviral activity of raoulic acid from Raoulia australis against Picornaviruses
    • Choi HJ, Lim CH, Song JH, Baek SH, Kwon DH, (2009) Antiviral activity of raoulic acid from Raoulia australis against Picornaviruses. Phytomedicine 16: 35-39.
    • (2009) Phytomedicine , vol.16 , pp. 35-39
    • Choi, H.J.1    Lim, C.H.2    Song, J.H.3    Baek, S.H.4    Kwon, D.H.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.