Modeling ALS with iPSCs reveals that mutant SOD1 misregulates neurofilament balance in motor neurons

Cell Stem Cell

Volumn 14, Issue 6, 2014, Pages 796-809

  Chen, Hong ^a,b   Qian, Kun ^a,b   Du, Zhongwei ^b   Cao, Jingyuan ^b   Petersen, Andrew ^b   Liu, Huisheng ^b   Blackbourn, Lisle W ^b   Huang, Cindytzu Ling ^b   Errigo, Anthony ^b   Yin, Yingnan ^b   Lu, Jianfeng ^b   Ayala, Melvin ^b   Zhang, Su Chun ^b,c  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b UNIVERSITY OF WISCONSIN MADISON   (United States)

^c UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COPPER ZINC SUPEROXIDE DISMUTASE; MUTANT PROTEIN; SUPEROXIDE DISMUTASE; MESSENGER RNA;

3' UNTRANSLATED REGION; AMYOTROPHIC LATERAL SCLEROSIS; ARTICLE; CELL AGGREGATION; EMBRYONIC STEM CELL; GENE EXPRESSION; GENE MUTATION; GLIA CELL; HUMAN; HUMAN CELL; MOTONEURON; NERVE FIBER DEGENERATION; NEUROFILAMENT; NEUROPATHOLOGY; PATHOGENESIS; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN RNA BINDING; BIOLOGICAL MODEL; GENETICS; INDUCED PLURIPOTENT STEM CELL; METABOLISM; MUTATION; PATHOLOGY; BINDING AFFINITY; CONTROLLED STUDY; GLIA; HUMAN CELL CULTURE; MUTANT; NERVE DEGENERATION; NEURITE;

AMYOTROPHIC LATERAL SCLEROSIS; HUMANS; INDUCED PLURIPOTENT STEM CELLS; MODELS, BIOLOGICAL; MOTOR NEURONS; MUTANT PROTEINS; MUTATION; SUPEROXIDE DISMUTASE;

EID: 84902134581     PISSN: 19345909     EISSN: 18759777     Source Type: Journal    
DOI: 10.1016/j.stem.2014.02.004     Document Type: Article

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