메뉴 건너뛰기




Volumn 2, Issue DEC, 2014, Pages

Mitochondrial metabolism and the control of vascular smooth muscle cell proliferation

Author keywords

Mitochondrial dynamics; Mitochondrial metabolism; Mitofusin 2; Proliferation; Vascular smooth muscle cell

Indexed keywords


EID: 84962668308     PISSN: None     EISSN: 2296634X     Source Type: Journal    
DOI: 10.3389/fcell.2014.00072     Document Type: Review
Times cited : (105)

References (97)
  • 1
    • 76749110211 scopus 로고    scopus 로고
    • Mitochondrial dysfunction enhances the migration of vascular smooth muscles cells via suppression of Akt phosphorylation
    • Ahn, S. Y., Choi, Y. S., Koo, H. J., Jeong, J. H., Park, W. H., Kim, M., et al. (2010). Mitochondrial dysfunction enhances the migration of vascular smooth muscles cells via suppression of Akt phosphorylation. Biochim. Biophys. Acta 1800, 275-281. doi: 10.1016/j.bbagen.2009.09.005
    • (2010) Biochim. Biophys. Acta , vol.1800 , pp. 275-281
    • Ahn, S.Y.1    Choi, Y.S.2    Koo, H.J.3    Jeong, J.H.4    Park, W.H.5    Kim, M.6
  • 2
    • 84872388657 scopus 로고    scopus 로고
    • Mitochondrial (dys)function and regulation of macrophage cholesterol efflux
    • Allen, A. M., Taylor, J. M., and Graham, A. (2013). Mitochondrial (dys)function and regulation of macrophage cholesterol efflux. Clin. Sci. Lond. 124, 509-515. doi: 10.1042/CS20120358
    • (2013) Clin. Sci. Lond , vol.124 , pp. 509-515
    • Allen, A.M.1    Taylor, J.M.2    Graham, A.3
  • 3
    • 39149106144 scopus 로고    scopus 로고
    • Mitochondrial metabolism, redox signaling, and fusion: a mitochondria-ROS-HIF-1alpha-Kv1.5 O2-sensing pathway at the intersection of pulmonary hypertension and cancer
    • Archer, S. L., Gomberg-Maitland, M., Maitland, M. L., Rich, S., Garcia, J. G., and Weir, E. K. (2008). Mitochondrial metabolism, redox signaling, and fusion: a mitochondria-ROS-HIF-1alpha-Kv1.5 O2-sensing pathway at the intersection of pulmonary hypertension and cancer. Am. J. Physiol. Heart. Circ. Physiol. 294, H570-H578. doi: 10.1152/ajpheart.01324.2007
    • (2008) Am. J. Physiol. Heart. Circ. Physiol , vol.294 , pp. H570-H578
    • Archer, S.L.1    Gomberg-Maitland, M.2    Maitland, M.L.3    Rich, S.4    Garcia, J.G.5    Weir, E.K.6
  • 4
    • 24144462451 scopus 로고    scopus 로고
    • Expression of Mfn2, the Charcot-Marie-Tooth neuropathy type 2A gene, in human skeletal muscle: effects of type 2 diabetes, obesity, weight loss, and the regulatory role of tumor necrosis factor alpha and interleukin-6
    • Bach, D., Naon, D., Pich, S., Soriano, F. X., Vega, N., Rieusset, J., et al. (2005). Expression of Mfn2, the Charcot-Marie-Tooth neuropathy type 2A gene, in human skeletal muscle: effects of type 2 diabetes, obesity, weight loss, and the regulatory role of tumor necrosis factor alpha and interleukin-6. Diabetes 54, 2685-2693. doi: 10.2337/diabetes.54.9.2685
    • (2005) Diabetes , vol.54 , pp. 2685-2693
    • Bach, D.1    Naon, D.2    Pich, S.3    Soriano, F.X.4    Vega, N.5    Rieusset, J.6
  • 6
    • 80051946060 scopus 로고    scopus 로고
    • Integrative genomics identifies MCU as an essential component of the mitochondrial calcium uniporter
    • Baughman, J. M., Perocchi, F., Girgis, H. S., Plovanich, M., Belcher-Timme, C. A., Sancak, Y., et al. (2011). Integrative genomics identifies MCU as an essential component of the mitochondrial calcium uniporter. Nature 476, 341-345. doi: 10.1038/nature10234
    • (2011) Nature , vol.476 , pp. 341-345
    • Baughman, J.M.1    Perocchi, F.2    Girgis, H.S.3    Plovanich, M.4    Belcher-Timme, C.A.5    Sancak, Y.6
  • 7
    • 0038125598 scopus 로고    scopus 로고
    • Calcium signalling: dynamics, homeostasis and remodelling
    • Berridge, M. J., Bootman, M. D., and Roderick, H. L. (2003). Calcium signalling: dynamics, homeostasis and remodelling. Nat. Rev. Mol. Cell Biol. 4, 517-529. doi: 10.1038/nrm1155
    • (2003) Nat. Rev. Mol. Cell Biol , vol.4 , pp. 517-529
    • Berridge, M.J.1    Bootman, M.D.2    Roderick, H.L.3
  • 8
    • 70350164417 scopus 로고    scopus 로고
    • How and why does the endoplasmic reticulum move?
    • Bola, B., and Allan, V. (2009). How and why does the endoplasmic reticulum move? Biochem. Soc. Trans. 37, 961-965. doi: 10.1042/BST0370961
    • (2009) Biochem. Soc. Trans , vol.37 , pp. 961-965
    • Bola, B.1    Allan, V.2
  • 9
    • 35248842739 scopus 로고    scopus 로고
    • Mitochondria on the move
    • Boldogh, I. R., and Pon, L. A. (2007). Mitochondria on the move. Trends Cell Biol. 17, 502-510. doi: 10.1016/j.tcb.2007.07.008
    • (2007) Trends Cell Biol , vol.17 , pp. 502-510
    • Boldogh, I.R.1    Pon, L.A.2
  • 10
    • 33745155785 scopus 로고    scopus 로고
    • An abnormal mitochondrial-hypoxia inducible factor-1alpha-Kv channel pathway disrupts oxygen sensing and triggers pulmonary arterial hypertension in fawn hooded rats: similarities to human pulmonary arterial hypertension
    • Bonnet, S., Michelakis, E. D., Porter, C. J., Andrade-Navarro, M. A., Thebaud, B., Bonnet, S., et al. (2006). An abnormal mitochondrial-hypoxia inducible factor-1alpha-Kv channel pathway disrupts oxygen sensing and triggers pulmonary arterial hypertension in fawn hooded rats: similarities to human pulmonary arterial hypertension. Circulation 113, 2630-2641. doi: 10.1161/CIRCULATIONAHA.105.609008
    • (2006) Circulation , vol.113 , pp. 2630-2641
    • Bonnet, S.1    Michelakis, E.D.2    Porter, C.J.3    Andrade-Navarro, M.A.4    Thebaud, B.5    Bonnet, S.6
  • 11
    • 34547456414 scopus 로고    scopus 로고
    • The nuclear factor of activated T cells in pulmonary arterial hypertension can be therapeutically targeted
    • Bonnet, S., Rochefort, G., Sutendra, G., Archer, S. L., Haromy, A., Webster, L., et al. (2007). The nuclear factor of activated T cells in pulmonary arterial hypertension can be therapeutically targeted. Proc. Natl. Acad. Sci. U.S.A. 104, 11418-11423. doi: 10.1073/pnas.0610467104
    • (2007) Proc. Natl. Acad. Sci. U.S.A , vol.104 , pp. 11418-11423
    • Bonnet, S.1    Rochefort, G.2    Sutendra, G.3    Archer, S.L.4    Haromy, A.5    Webster, L.6
  • 13
    • 79960310339 scopus 로고    scopus 로고
    • Increased ER-mitochondrial coupling promotes mitochondrial respiration and bioenergetics during early phases of ER stress
    • Bravo, R., Vicencio, J. M., Parra, V., Troncoso, R., Munoz, J. P., Bui, M., et al. (2011). Increased ER-mitochondrial coupling promotes mitochondrial respiration and bioenergetics during early phases of ER stress. J. Cell Sci. 124, 2143-2152. doi: 10.1242/jcs.080762
    • (2011) J. Cell Sci , vol.124 , pp. 2143-2152
    • Bravo, R.1    Vicencio, J.M.2    Parra, V.3    Troncoso, R.4    Munoz, J.P.5    Bui, M.6
  • 16
    • 0021894471 scopus 로고
    • High-energy phosphate metabolism in vascular smooth muscle
    • Butler, T. M., and Siegman, M. J. (1985). High-energy phosphate metabolism in vascular smooth muscle. Annu. Rev. Physiol. 47, 629-643. doi: 10.1146/annurev.ph.47.030185.003213
    • (1985) Annu. Rev. Physiol , vol.47 , pp. 629-643
    • Butler, T.M.1    Siegman, M.J.2
  • 17
    • 0021963924 scopus 로고
    • Smooth muscle phenotypic changes in arterial wall homeostasis: implications for the pathogenesis of atherosclerosis
    • Campbell, G. R., and Campbell, J. H. (1985). Smooth muscle phenotypic changes in arterial wall homeostasis: implications for the pathogenesis of atherosclerosis. Exp. Mol. Pathol. 42, 139-162. doi: 10.1016/0014-4800(85)90023-1
    • (1985) Exp. Mol. Pathol , vol.42 , pp. 139-162
    • Campbell, G.R.1    Campbell, J.H.2
  • 18
    • 77955041880 scopus 로고    scopus 로고
    • Essential regulation of cell bioenergetics by constitutive InsP3 receptor Ca2+ transfer to mitochondria
    • Cardenas, C., Miller, R. A., Smith, I., Bui, T., Molgo, J., Muller, M., et al. (2010). Essential regulation of cell bioenergetics by constitutive InsP3 receptor Ca2+ transfer to mitochondria. Cell 142, 270-283. doi: 10.1016/j.cell.2010.06.007
    • (2010) Cell , vol.142 , pp. 270-283
    • Cardenas, C.1    Miller, R.A.2    Smith, I.3    Bui, T.4    Molgo, J.5    Muller, M.6
  • 19
    • 56349110884 scopus 로고    scopus 로고
    • Control of mitochondria dynamics and oxidative metabolism by cAMP, AKAPs and the proteasome
    • Carlucci, A., Lignitto, L., and Feliciello, A. (2008). Control of mitochondria dynamics and oxidative metabolism by cAMP, AKAPs and the proteasome. Trends Cell Biol. 18, 604-613. doi: 10.1016/j.tcb.2008.09.006
    • (2008) Trends Cell Biol , vol.18 , pp. 604-613
    • Carlucci, A.1    Lignitto, L.2    Feliciello, A.3
  • 20
    • 79953804545 scopus 로고    scopus 로고
    • Vascular smooth-muscle-cell activation: proteomics point of view
    • Cecchettini, A., Rocchiccioli, S., Boccardi, C., and Citti, L. (2011). Vascular smooth-muscle-cell activation: proteomics point of view. Int. Rev. Cell Mol. Biol. 288, 43-99. doi: 10.1016/B978-0-12-386041-5.00002-9
    • (2011) Int. Rev. Cell Mol. Biol , vol.288 , pp. 43-99
    • Cecchettini, A.1    Rocchiccioli, S.2    Boccardi, C.3    Citti, L.4
  • 21
    • 36048945306 scopus 로고    scopus 로고
    • Regulation of mitochondrial fusion and division
    • Cerveny, K. L., Tamura, Y., Zhang, Z., Jensen, R. E., and Sesaki, H. (2007). Regulation of mitochondrial fusion and division. Trends Cell Biol. 17, 563-569. doi: 10.1016/j.tcb.2007.08.006
    • (2007) Trends Cell Biol , vol.17 , pp. 563-569
    • Cerveny, K.L.1    Tamura, Y.2    Zhang, Z.3    Jensen, R.E.4    Sesaki, H.5
  • 22
    • 27744491193 scopus 로고    scopus 로고
    • Emerging functions of mammalian mitochondrial fusion and fission
    • Chen, H., and Chan, D. C. (2005). Emerging functions of mammalian mitochondrial fusion and fission. Hum. Mol. Genet. 14, R283-R289. doi: 10.1093/hmg/ddi270
    • (2005) Hum. Mol. Genet , vol.14 , pp. R283-R289
    • Chen, H.1    Chan, D.C.2
  • 23
    • 0037455575 scopus 로고    scopus 로고
    • Mitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic development
    • Chen, H., Detmer, S. A., Ewald, A. J., Griffin, E. E., Fraser, S. E., and Chan, D. C. (2003). Mitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic development. J. Cell Biol. 160, 189-200. doi: 10.1083/jcb.200211046
    • (2003) J. Cell Biol , vol.160 , pp. 189-200
    • Chen, H.1    Detmer, S.A.2    Ewald, A.J.3    Griffin, E.E.4    Fraser, S.E.5    Chan, D.C.6
  • 24
    • 4444270915 scopus 로고    scopus 로고
    • Dysregulation of HSG triggers vascular proliferative disorders
    • Chen, K. H., Guo, X., Ma, D., Guo, Y., Li, Q., Yang, D., et al. (2004). Dysregulation of HSG triggers vascular proliferative disorders. Nat. Cell Biol. 6, 872-883. doi: 10.1038/ncb1161
    • (2004) Nat. Cell Biol , vol.6 , pp. 872-883
    • Chen, K.H.1    Guo, X.2    Ma, D.3    Guo, Y.4    Li, Q.5    Yang, D.6
  • 25
    • 70449724857 scopus 로고    scopus 로고
    • Mitochondrial OPA1, apoptosis, and heart failure
    • Chen, L., Gong, Q., Stice, J. P., and Knowlton, A. A. (2009). Mitochondrial OPA1, apoptosis, and heart failure. Cardiovasc. Res. 84, 91-99. doi: 10.1093/cvr/cvp181
    • (2009) Cardiovasc. Res , vol.84 , pp. 91-99
    • Chen, L.1    Gong, Q.2    Stice, J.P.3    Knowlton, A.A.4
  • 26
    • 33748469506 scopus 로고    scopus 로고
    • Apoptosis of vascular smooth muscle cells induces features of plaque vulnerability in atherosclerosis
    • Clarke, M. C., Figg, N., Maguire, J. J., Davenport, A. P., Goddard, M., Littlewood, T. D., et al. (2006). Apoptosis of vascular smooth muscle cells induces features of plaque vulnerability in atherosclerosis. Nat. Med. 12, 1075-1080. doi: 10.1038/nm1459
    • (2006) Nat. Med , vol.12 , pp. 1075-1080
    • Clarke, M.C.1    Figg, N.2    Maguire, J.J.3    Davenport, A.P.4    Goddard, M.5    Littlewood, T.D.6
  • 27
    • 0036565666 scopus 로고    scopus 로고
    • tcBid promotes Ca(2+) signal propagation to the mitochondria: control of Ca(2+) permeation through the outer mitochondrial membrane
    • Csordas, G., Madesh, M., Antonsson, B., and Hajnoczky, G. (2002). tcBid promotes Ca(2+) signal propagation to the mitochondria: control of Ca(2+) permeation through the outer mitochondrial membrane. EMBO J. 21, 2198-2206. doi: 10.1093/emboj/21.9.2198
    • (2002) EMBO J , vol.21 , pp. 2198-2206
    • Csordas, G.1    Madesh, M.2    Antonsson, B.3    Hajnoczky, G.4
  • 28
    • 0033521586 scopus 로고    scopus 로고
    • Quasi-synaptic calcium signal transmission between endoplasmic reticulum and mitochondria
    • Csordas, G., Thomas, A. P., and Hajnoczky, G. (1999). Quasi-synaptic calcium signal transmission between endoplasmic reticulum and mitochondria. EMBO J. 18, 96-108. doi: 10.1093/emboj/18.1.96
    • (1999) EMBO J , vol.18 , pp. 96-108
    • Csordas, G.1    Thomas, A.P.2    Hajnoczky, G.3
  • 29
    • 57349100367 scopus 로고    scopus 로고
    • Mitofusin 2 tethers endoplasmic reticulum to mitochondria
    • De Brito, O. M., and Scorrano, L. (2008). Mitofusin 2 tethers endoplasmic reticulum to mitochondria. Nature 456, 605-610. doi: 10.1038/nature07534
    • (2008) Nature , vol.456 , pp. 605-610
    • De Brito, O.M.1    Scorrano, L.2
  • 30
    • 84891522787 scopus 로고    scopus 로고
    • Mitochondrial fragmentation impairs insulin-dependent glucose uptake by modulating Akt activity through mitochondrial Ca2+ uptake
    • Del Campo, A., Parra, V., Vasquez-Trincado, C., Gutierrez, T., Morales, P. E., Lopez-Crisosto, C., et al. (2014). Mitochondrial fragmentation impairs insulin-dependent glucose uptake by modulating Akt activity through mitochondrial Ca2+ uptake. Am. J. Physiol. Endocrinol. Metab. 306, E1-E13. doi: 10.1152/ajpendo.00146.2013
    • (2014) Am. J. Physiol. Endocrinol. Metab , vol.306 , pp. E1-E13
    • Del Campo, A.1    Parra, V.2    Vasquez-Trincado, C.3    Gutierrez, T.4    Morales, P.E.5    Lopez-Crisosto, C.6
  • 31
    • 68649090226 scopus 로고    scopus 로고
    • Regulation of mitochondrial dehydrogenases by calcium ions
    • Denton, R. M. (2009). Regulation of mitochondrial dehydrogenases by calcium ions. Biochim. Biophys. Acta 1787, 1309-1316. doi: 10.1016/j.bbabio.2009.01.005
    • (2009) Biochim. Biophys. Acta , vol.1787 , pp. 1309-1316
    • Denton, R.M.1
  • 32
    • 0025195166 scopus 로고
    • Ca2+ as a second messenger within mitochondria of the heart and other tissues
    • Denton, R. M., and Mccormack, J. G. (1990). Ca2+ as a second messenger within mitochondria of the heart and other tissues. Annu. Rev. Physiol. 52, 451-466. doi: 10.1146/annurev.ph.52.030190.002315
    • (1990) Annu. Rev. Physiol , vol.52 , pp. 451-466
    • Denton, R.M.1    Mccormack, J.G.2
  • 33
    • 80051936634 scopus 로고    scopus 로고
    • A forty-kilodalton protein of the inner membrane is the mitochondrial calcium uniporter
    • De Stefani, D., Raffaello, A., Teardo, E., Szabo, I., and Rizzuto, R. (2011). A forty-kilodalton protein of the inner membrane is the mitochondrial calcium uniporter. Nature 476, 336-340. doi: 10.1038/nature10230
    • (2011) Nature , vol.476 , pp. 336-340
    • De Stefani, D.1    Raffaello, A.2    Teardo, E.3    Szabo, I.4    Rizzuto, R.5
  • 34
    • 78149409004 scopus 로고    scopus 로고
    • The role of mitochondria in pulmonary vascular remodeling
    • Dromparis, P., Sutendra, G., and Michelakis, E. D. (2010). The role of mitochondria in pulmonary vascular remodeling. J. Mol. Med. Berl. 88, 1003-1010. doi: 10.1007/s00109-010-0670-x
    • (2010) J. Mol. Med. Berl , vol.88 , pp. 1003-1010
    • Dromparis, P.1    Sutendra, G.2    Michelakis, E.D.3
  • 36
    • 33845976357 scopus 로고    scopus 로고
    • Proteolytic processing of OPA1 links mitochondrial dysfunction to alterations in mitochondrial morphology
    • Duvezin-Caubet, S., Jagasia, R., Wagener, J., Hofmann, S., Trifunovic, A., Hansson, A., et al. (2006). Proteolytic processing of OPA1 links mitochondrial dysfunction to alterations in mitochondrial morphology. J. Biol. Chem. 281, 37972-37979. doi: 10.1074/jbc.M606059200
    • (2006) J. Biol. Chem , vol.281 , pp. 37972-37979
    • Duvezin-Caubet, S.1    Jagasia, R.2    Wagener, J.3    Hofmann, S.4    Trifunovic, A.5    Hansson, A.6
  • 37
    • 0027933701 scopus 로고
    • Isolated cerebral and cerebellar mitochondria produce free radicals when exposed to elevated CA2+ and Na+: implications for neurodegeneration
    • Dykens, J. A. (1994). Isolated cerebral and cerebellar mitochondria produce free radicals when exposed to elevated CA2+ and Na+: implications for neurodegeneration. J. Neurochem. 63, 584-591. doi: 10.1046/j.1471-4159.1994.63020584.x
    • (1994) J. Neurochem , vol.63 , pp. 584-591
    • Dykens, J.A.1
  • 38
    • 84876011203 scopus 로고    scopus 로고
    • Endoplasmic reticulum structure and interconnections with other organelles
    • English, A. R., and Voeltz, G. K. (2013). Endoplasmic reticulum structure and interconnections with other organelles. Cold Spring Harb. Perspect. Biol. 5:a013227. doi: 10.1101/cshperspect.a013227
    • (2013) Cold Spring Harb. Perspect. Biol , vol.5
    • English, A.R.1    Voeltz, G.K.2
  • 39
    • 37149007657 scopus 로고    scopus 로고
    • Is atherosclerosis a mitochondrial disorder?
    • Finsterer, J. (2007). Is atherosclerosis a mitochondrial disorder? Vasa 36, 229-240. doi: 10.1024/0301-1526.36.4.229
    • (2007) Vasa , vol.36 , pp. 229-240
    • Finsterer, J.1
  • 40
    • 68649120751 scopus 로고    scopus 로고
    • Mitochondrial calcium as a key regulator of mitochondrial ATP production in mammalian cells
    • Griffiths, E. J., and Rutter, G. A. (2009). Mitochondrial calcium as a key regulator of mitochondrial ATP production in mammalian cells. Biochim. Biophys. Acta 1787, 1324-1333. doi: 10.1016/j.bbabio.2009.01.019
    • (2009) Biochim. Biophys. Acta , vol.1787 , pp. 1324-1333
    • Griffiths, E.J.1    Rutter, G.A.2
  • 41
    • 36348989007 scopus 로고    scopus 로고
    • Mitofusin 2 triggers vascular smooth muscle cell apoptosis via mitochondrial death pathway
    • Guo, X., Chen, K. H., Guo, Y., Liao, H., Tang, J., and Xiao, R. P. (2007a). Mitofusin 2 triggers vascular smooth muscle cell apoptosis via mitochondrial death pathway. Circ. Res. 101, 1113-1122. doi: 10.1161/CIRCRESAHA.107.157644
    • (2007) Circ. Res , vol.101 , pp. 1113-1122
    • Guo, X.1    Chen, K.H.2    Guo, Y.3    Liao, H.4    Tang, J.5    Xiao, R.P.6
  • 42
    • 34848907989 scopus 로고    scopus 로고
    • Overexpression of Mitofusin 2 inhibited oxidized low-density lipoprotein induced vascular smooth muscle cell proliferation and reduced atherosclerotic lesion formation in rabbit
    • Guo, Y. H., Chen, K., Gao, W., Li, Q., Chen, L., Wang, G. S., et al. (2007b). Overexpression of Mitofusin 2 inhibited oxidized low-density lipoprotein induced vascular smooth muscle cell proliferation and reduced atherosclerotic lesion formation in rabbit. Biochem. Biophys. Res. Commun. 363, 411-417. doi: 10.1016/j.bbrc.2007.08.191
    • (2007) Biochem. Biophys. Res. Commun , vol.363 , pp. 411-417
    • Guo, Y.H.1    Chen, K.2    Gao, W.3    Li, Q.4    Chen, L.5    Wang, G.S.6
  • 43
    • 77649244994 scopus 로고    scopus 로고
    • Subjects with early-onset type 2 diabetes show defective activation of the skeletal muscle PGC-1α/Mitofusin-2 regulatory pathway in response to physical activity
    • Hernandez-Alvarez, M. I., Thabit, H., Burns, N., Shah, S., Brema, I., Hatunic, M., et al. (2010). Subjects with early-onset type 2 diabetes show defective activation of the skeletal muscle PGC-1α/Mitofusin-2 regulatory pathway in response to physical activity. Diabetes Care 33, 645-651. doi: 10.2337/dc09-1305
    • (2010) Diabetes Care , vol.33 , pp. 645-651
    • Hernandez-Alvarez, M.I.1    Thabit, H.2    Burns, N.3    Shah, S.4    Brema, I.5    Hatunic, M.6
  • 44
    • 84909619435 scopus 로고    scopus 로고
    • The regulation of mitochondrial dynamics
    • Hoppins, S. (2014). The regulation of mitochondrial dynamics. Curr. Opin. Cell Biol. 29, 46-52. doi: 10.1016/j.ceb.2014.03.005
    • (2014) Curr. Opin. Cell Biol , vol.29 , pp. 46-52
    • Hoppins, S.1
  • 45
    • 68249087424 scopus 로고    scopus 로고
    • Mitochondrial fission factor Drp1 is essential for embryonic development and synapse formation in mice
    • Ishihara, N., Nomura, M., Jofuku, A., Kato, H., Suzuki, S. O., Masuda, K., et al. (2009). Mitochondrial fission factor Drp1 is essential for embryonic development and synapse formation in mice. Nat. Cell Biol. 11, 958-966. doi: 10.1038/ncb1907
    • (2009) Nat. Cell Biol , vol.11 , pp. 958-966
    • Ishihara, N.1    Nomura, M.2    Jofuku, A.3    Kato, H.4    Suzuki, S.O.5    Masuda, K.6
  • 46
    • 79551600416 scopus 로고    scopus 로고
    • Fis1 and Bap31 bridge the mitochondria-ER interface to establish a platform for apoptosis induction
    • Iwasawa, R., Mahul-Mellier, A. L., Datler, C., Pazarentzos, E., and Grimm, S. (2011). Fis1 and Bap31 bridge the mitochondria-ER interface to establish a platform for apoptosis induction. EMBO J. 30, 556-568. doi: 10.1038/emboj.2010.346
    • (2011) EMBO J , vol.30 , pp. 556-568
    • Iwasawa, R.1    Mahul-Mellier, A.L.2    Datler, C.3    Pazarentzos, E.4    Grimm, S.5
  • 47
    • 0141592470 scopus 로고    scopus 로고
    • hFis1, a novel component of the mammalian mitochondrial fission machinery
    • James, D. I., Parone, P. A., Mattenberger, Y., and Martinou, J. C. (2003). hFis1, a novel component of the mammalian mitochondrial fission machinery. J. Biol. Chem. 278, 36373-36379. doi: 10.1074/jbc.M303758200
    • (2003) J. Biol. Chem , vol.278 , pp. 36373-36379
    • James, D.I.1    Parone, P.A.2    Mattenberger, Y.3    Martinou, J.C.4
  • 48
    • 46849083933 scopus 로고    scopus 로고
    • Abrogation of mitochondrial transcription in smooth muscle cells impairs smooth muscle contractility and vascular tone
    • Jawien, J., Bian, Z., Sheikine, Y., Olofsson, P. S., Pang, Y., Edholm, T., et al. (2008). Abrogation of mitochondrial transcription in smooth muscle cells impairs smooth muscle contractility and vascular tone. J. Physiol. Pharmacol. 59, 239-252
    • (2008) J. Physiol. Pharmacol , vol.59 , pp. 239-252
    • Jawien, J.1    Bian, Z.2    Sheikine, Y.3    Olofsson, P.S.4    Pang, Y.5    Edholm, T.6
  • 49
    • 0029064633 scopus 로고
    • Intramitochondrial protein synthesis is regulated by matrix adenine nucleotide content and requires calcium
    • Joyal, J. L., Hagen, T., and Aprille, J. R. (1995). Intramitochondrial protein synthesis is regulated by matrix adenine nucleotide content and requires calcium. Arch. Biochem. Biophys. 319, 322-330. doi: 10.1006/abbi.1995.1300
    • (1995) Arch. Biochem. Biophys , vol.319 , pp. 322-330
    • Joyal, J.L.1    Hagen, T.2    Aprille, J.R.3
  • 50
    • 84876130820 scopus 로고    scopus 로고
    • Comparison of edge vascular response after sirolimus-and paclitaxel-eluting stent implantation
    • Kang, W. C., Park, Y. M., Shin, K. C., Moon, C. I., Lee, K., Han, S. H., et al. (2011). Comparison of edge vascular response after sirolimus-and paclitaxel-eluting stent implantation. Int. J. Cardiol. 165, 46-50. doi: 10.1016/j.ijcard.2011.07.108
    • (2011) Int. J. Cardiol , vol.165 , pp. 46-50
    • Kang, W.C.1    Park, Y.M.2    Shin, K.C.3    Moon, C.I.4    Lee, K.5    Han, S.H.6
  • 51
    • 1642540210 scopus 로고    scopus 로고
    • The mitochondrial calcium uniporter is a highly selective ion channel
    • Kirichok, Y., Krapivinsky, G., and Clapham, D. E. (2004). The mitochondrial calcium uniporter is a highly selective ion channel. Nature 427, 360-364. doi: 10.1038/nature02246
    • (2004) Nature , vol.427 , pp. 360-364
    • Kirichok, Y.1    Krapivinsky, G.2    Clapham, D.E.3
  • 52
    • 84872769447 scopus 로고    scopus 로고
    • An actin-dependent step in mitochondrial fission mediated by the ER-associated formin INF2
    • Korobova, F., Ramabhadran, V., and Higgs, H. N. (2013). An actin-dependent step in mitochondrial fission mediated by the ER-associated formin INF2. Science 339, 464-467. doi: 10.1126/science.1228360
    • (2013) Science , vol.339 , pp. 464-467
    • Korobova, F.1    Ramabhadran, V.2    Higgs, H.N.3
  • 55
    • 0029861775 scopus 로고    scopus 로고
    • The role of pyridine dinucleotides in regulating the permeability of the mitochondrial outer membrane
    • Lee, A. C., Xu, X., and Colombini, M. (1996). The role of pyridine dinucleotides in regulating the permeability of the mitochondrial outer membrane. J. Biol. Chem. 271, 26724-26731. doi: 10.1074/jbc.271.43.26724
    • (1996) J. Biol. Chem , vol.271 , pp. 26724-26731
    • Lee, A.C.1    Xu, X.2    Colombini, M.3
  • 56
    • 67650688732 scopus 로고    scopus 로고
    • Regulation of mitochondrial Ca2+ and its effects on energetics and redox balance in normal and failing heart
    • Liu, T., and O'Rourke, B. (2009). Regulation of mitochondrial Ca2+ and its effects on energetics and redox balance in normal and failing heart. J. Bioenerg. Biomembr. 41, 127-132. doi: 10.1007/s10863-009-9216-8
    • (2009) J. Bioenerg. Biomembr , vol.41 , pp. 127-132
    • Liu, T.1    O'Rourke, B.2
  • 58
    • 84861640093 scopus 로고    scopus 로고
    • Dynamin-related protein 1-mediated mitochondrial mitotic fission permits hyperproliferation of vascular smooth muscle cells and offers a novel therapeutic target in pulmonary hypertension
    • Marsboom, G., Toth, P. T., Ryan, J. J., Hong, Z., Wu, X., Fang, Y. H., et al. (2012). Dynamin-related protein 1-mediated mitochondrial mitotic fission permits hyperproliferation of vascular smooth muscle cells and offers a novel therapeutic target in pulmonary hypertension. Circ. Res. 110, 1484-1497. doi: 10.1161/CIRCRESAHA.111.263848
    • (2012) Circ. Res , vol.110 , pp. 1484-1497
    • Marsboom, G.1    Toth, P.T.2    Ryan, J.J.3    Hong, Z.4    Wu, X.5    Fang, Y.H.6
  • 59
    • 6344257102 scopus 로고    scopus 로고
    • Dichloroacetate prevents and reverses pulmonary hypertension by inducing pulmonary artery smooth muscle cell apoptosis
    • Mcmurtry, M. S., Bonnet, S., Wu, X., Dyck, J. R., Haromy, A., Hashimoto, K., et al. (2004). Dichloroacetate prevents and reverses pulmonary hypertension by inducing pulmonary artery smooth muscle cell apoptosis. Circ. Res. 95, 830-840. doi: 10.1161/01.RES.0000145360.16770.9f
    • (2004) Circ. Res , vol.95 , pp. 830-840
    • Mcmurtry, M.S.1    Bonnet, S.2    Wu, X.3    Dyck, J.R.4    Haromy, A.5    Hashimoto, K.6
  • 60
    • 0037188928 scopus 로고    scopus 로고
    • Diversity in mitochondrial function explains differences in vascular oxygen sensing
    • Michelakis, E. D., Hampl, V., Nsair, A., Wu, X., Harry, G., Haromy, A., et al. (2002). Diversity in mitochondrial function explains differences in vascular oxygen sensing. Circ. Res. 90, 1307-1315. doi: 10.1161/01.RES.0000024689.07590.C2
    • (2002) Circ. Res , vol.90 , pp. 1307-1315
    • Michelakis, E.D.1    Hampl, V.2    Nsair, A.3    Wu, X.4    Harry, G.5    Haromy, A.6
  • 61
    • 84910141948 scopus 로고    scopus 로고
    • Mitochondrial dynamics and inheritance during cell division, development and disease
    • Mishra, P., and Chan, D. C. (2014). Mitochondrial dynamics and inheritance during cell division, development and disease. Nat. Rev. Mol. Cell Biol. 15, 634-646. doi: 10.1038/nrm3877
    • (2014) Nat. Rev. Mol. Cell Biol , vol.15 , pp. 634-646
    • Mishra, P.1    Chan, D.C.2
  • 62
    • 84885381258 scopus 로고    scopus 로고
    • Mitochondrial fission-fusion as an emerging key regulator of cell proliferation and differentiation
    • Mitra, K. (2013). Mitochondrial fission-fusion as an emerging key regulator of cell proliferation and differentiation. Bioessays 35, 955-964. doi: 10.1002/bies.201300011
    • (2013) Bioessays , vol.35 , pp. 955-964
    • Mitra, K.1
  • 63
    • 84864748956 scopus 로고    scopus 로고
    • Fulfilling the metabolic requirements for cell proliferation
    • Moncada, S., Higgs, E. A., and Colombo, S. L. (2012). Fulfilling the metabolic requirements for cell proliferation. Biochem. J. 446, 1-7. doi: 10.1042/BJ20120427
    • (2012) Biochem. J , vol.446 , pp. 1-7
    • Moncada, S.1    Higgs, E.A.2    Colombo, S.L.3
  • 64
    • 84897979984 scopus 로고    scopus 로고
    • GLP-1 promotes mitochondrial metabolism in vascular smooth muscle cells by enhancing endoplasmic reticulum-mitochondria coupling
    • Morales, P. E., Torres, G., Sotomayor-Flores, C., Pena-Oyarzun, D., Rivera-Mejias, P., Paredes, F., et al. (2014). GLP-1 promotes mitochondrial metabolism in vascular smooth muscle cells by enhancing endoplasmic reticulum-mitochondria coupling. Biochem. Biophys. Res. Commun. 446, 410-416. doi: 10.1016/j.bbrc.2014.03.004
    • (2014) Biochem. Biophys. Res. Commun , vol.446 , pp. 410-416
    • Morales, P.E.1    Torres, G.2    Sotomayor-Flores, C.3    Pena-Oyarzun, D.4    Rivera-Mejias, P.5    Paredes, F.6
  • 65
    • 84905043685 scopus 로고    scopus 로고
    • At the right distance: ER-mitochondria juxtaposition in cell life and death
    • Naon, D., and Scorrano, L. (2014). At the right distance: ER-mitochondria juxtaposition in cell life and death. Biochim. Biophys. Acta 1843, 2184-2194. doi: 10.1016/j.bbamcr.2014.05.011
    • (2014) Biochim. Biophys. Acta , vol.1843 , pp. 2184-2194
    • Naon, D.1    Scorrano, L.2
  • 66
    • 84908138540 scopus 로고    scopus 로고
    • Mitochondrial dynamics in the central regulation of metabolism
    • Nasrallah, C. M., and Horvath, T. L. (2014). Mitochondrial dynamics in the central regulation of metabolism. Nat. Rev. Endocrinol. 10, 650-658. doi: 10.1038/nrendo.2014.160
    • (2014) Nat. Rev. Endocrinol , vol.10 , pp. 650-658
    • Nasrallah, C.M.1    Horvath, T.L.2
  • 67
    • 84884574238 scopus 로고    scopus 로고
    • Adaptor proteins MiD49 and MiD51 can act independently of Mff and Fis1 in Drp1 recruitment and are specific for mitochondrial fission
    • Palmer, C. S., Elgass, K. D., Parton, R. G., Osellame, L. D., Stojanovski, D., and Ryan, M. T. (2013). Adaptor proteins MiD49 and MiD51 can act independently of Mff and Fis1 in Drp1 recruitment and are specific for mitochondrial fission. J. Biol. Chem. 288, 27584-27593. doi: 10.1074/jbc.M113.479873
    • (2013) J. Biol. Chem , vol.288 , pp. 27584-27593
    • Palmer, C.S.1    Elgass, K.D.2    Parton, R.G.3    Osellame, L.D.4    Stojanovski, D.5    Ryan, M.T.6
  • 68
    • 52449134835 scopus 로고    scopus 로고
    • Preventing mitochondrial fission impairs mitochondrial function and leads to loss of mitochondrial DNA
    • Parone, P. A., Da Cruz, S., Tondera, D., Mattenberger, Y., James, D. I., Maechler, P., et al. (2008). Preventing mitochondrial fission impairs mitochondrial function and leads to loss of mitochondrial DNA. PLoS ONE 3:e3257. doi: 10.1371/journal.pone.0003257
    • (2008) PLoS ONE , vol.3
    • Parone, P.A.1    Da Cruz, S.2    Tondera, D.3    Mattenberger, Y.4    James, D.I.5    Maechler, P.6
  • 69
    • 38849095253 scopus 로고    scopus 로고
    • Changes in mitochondrial dynamics during ceramide-induced cardiomyocyte early apoptosis
    • Parra, V., Eisner, V., Chiong, M., Criollo, A., Moraga, F., Garcia, A., et al. (2008). Changes in mitochondrial dynamics during ceramide-induced cardiomyocyte early apoptosis. Cardiovasc. Res. 77, 387-397. doi: 10.1093/cvr/cvm029
    • (2008) Cardiovasc. Res , vol.77 , pp. 387-397
    • Parra, V.1    Eisner, V.2    Chiong, M.3    Criollo, A.4    Moraga, F.5    Garcia, A.6
  • 70
  • 71
    • 84891801047 scopus 로고    scopus 로고
    • Insulin stimulates mitochondrial fusion and function in cardiomyocytes via the Akt-mTOR-NFkappaB-Opa-1 signaling pathway
    • Parra, V., Verdejo, H. E., Iglewski, M., Del Campo, A., Troncoso, R., Jones, D., et al. (2014). Insulin stimulates mitochondrial fusion and function in cardiomyocytes via the Akt-mTOR-NFkappaB-Opa-1 signaling pathway. Diabetes 63, 75-88. doi: 10.2337/db13-0340
    • (2014) Diabetes , vol.63 , pp. 75-88
    • Parra, V.1    Verdejo, H.E.2    Iglewski, M.3    Del Campo, A.4    Troncoso, R.5    Jones, D.6
  • 72
    • 0020582997 scopus 로고
    • Functional compartmentalization of oxidative and glycolytic metabolism in vascular smooth muscle
    • Paul, R. J. (1983). Functional compartmentalization of oxidative and glycolytic metabolism in vascular smooth muscle. Am. J. Physiol. Cell Physiol. 244, C399-C409
    • (1983) Am. J. Physiol. Cell Physiol , vol.244 , pp. C399-C409
    • Paul, R.J.1
  • 73
    • 84902455654 scopus 로고    scopus 로고
    • Mitochondrial fission is required for cardiomyocyte hypertrophy via a Ca2+-calcineurin signalling pathway
    • Pennanen, C., Parra, V., Lopez-Crisosto, C., Morales, P. E., Del Campo, A., Gutierrez, T., et al. (2014). Mitochondrial fission is required for cardiomyocyte hypertrophy via a Ca2+-calcineurin signalling pathway. J. Cell Sci. 127, 2659-2671. doi: 10.1242/jcs.139394
    • (2014) J. Cell Sci , vol.127 , pp. 2659-2671
    • Pennanen, C.1    Parra, V.2    Lopez-Crisosto, C.3    Morales, P.E.4    Del Campo, A.5    Gutierrez, T.6
  • 74
    • 20444461625 scopus 로고    scopus 로고
    • The Charcot-Marie-Tooth type 2A gene product, Mfn2, up-regulates fuel oxidation through expression of OXPHOS system
    • Pich, S., Bach, D., Briones, P., Liesa, M., Camps, M., Testar, X., et al. (2005). The Charcot-Marie-Tooth type 2A gene product, Mfn2, up-regulates fuel oxidation through expression of OXPHOS system. Hum. Mol. Genet. 14, 1405-1415. doi: 10.1093/hmg/ddi149
    • (2005) Hum. Mol. Genet , vol.14 , pp. 1405-1415
    • Pich, S.1    Bach, D.2    Briones, P.3    Liesa, M.4    Camps, M.5    Testar, X.6
  • 75
    • 0037175393 scopus 로고    scopus 로고
    • Recombinant expression of the voltage-dependent anion channel enhances the transfer of Ca2+ microdomains to mitochondria
    • Rapizzi, E., Pinton, P., Szabadkai, G., Wieckowski, M. R., Vandecasteele, G., Baird, G., et al. (2002). Recombinant expression of the voltage-dependent anion channel enhances the transfer of Ca2+ microdomains to mitochondria. J. Cell Biol. 159, 613-624. doi: 10.1083/jcb.200205091
    • (2002) J. Cell Biol , vol.159 , pp. 613-624
    • Rapizzi, E.1    Pinton, P.2    Szabadkai, G.3    Wieckowski, M.R.4    Vandecasteele, G.5    Baird, G.6
  • 77
    • 84866728707 scopus 로고    scopus 로고
    • Endoplasmic reticulum-mitochondria contacts: function of the junction
    • Rowland, A. A., and Voeltz, G. K. (2012). Endoplasmic reticulum-mitochondria contacts: function of the junction. Nat. Rev. Mol. Cell Biol. 13, 607-625. doi: 10.1038/nrm3440
    • (2012) Nat. Rev. Mol. Cell Biol , vol.13 , pp. 607-625
    • Rowland, A.A.1    Voeltz, G.K.2
  • 78
    • 34249307295 scopus 로고    scopus 로고
    • Regulation of vascular smooth muscle cell differentiation
    • Rzucidlo, E. M., Martin, K. A., and Powell, R. J. (2007). Regulation of vascular smooth muscle cell differentiation. J. Vasc. Surg. 45(Suppl. A), A25-A32. doi: 10.1016/j.jvs.2007.03.001
    • (2007) J. Vasc. Surg , vol.45
    • Rzucidlo, E.M.1    Martin, K.A.2    Powell, R.J.3
  • 79
    • 84893307629 scopus 로고    scopus 로고
    • Mitochondrial fission induced by platelet-derived growth factor regulates vascular smooth muscle cell bioenergetics and cell proliferation
    • Salabei, J. K., and Hill, B. G. (2013). Mitochondrial fission induced by platelet-derived growth factor regulates vascular smooth muscle cell bioenergetics and cell proliferation. Redox Biol. 1, 542-551. doi: 10.1016/j.redox.2013.10.011
    • (2013) Redox Biol , vol.1 , pp. 542-551
    • Salabei, J.K.1    Hill, B.G.2
  • 80
    • 0035797119 scopus 로고    scopus 로고
    • Mitochondria make a come back
    • Scheffler, I. E. (2001). Mitochondria make a come back. Adv. Drug Deliv. Rev. 49, 3-26. doi: 10.1016/S0169-409X(01)00123-5
    • (2001) Adv. Drug Deliv. Rev , vol.49 , pp. 3-26
    • Scheffler, I.E.1
  • 81
    • 0036257364 scopus 로고    scopus 로고
    • Voltage-dependent anion-selective channel (VDAC) interacts with the dynein light chain Tctex1 and the heat-shock protein PBP74
    • Schwarzer, C., Barnikol-Watanabe, S., Thinnes, F. P., and Hilschmann, N. (2002). Voltage-dependent anion-selective channel (VDAC) interacts with the dynein light chain Tctex1 and the heat-shock protein PBP74. Int. J. Biochem. Cell Biol. 34, 1059-1070. doi: 10.1016/S1357-2725(02)00026-2
    • (2002) Int. J. Biochem. Cell Biol , vol.34 , pp. 1059-1070
    • Schwarzer, C.1    Barnikol-Watanabe, S.2    Thinnes, F.P.3    Hilschmann, N.4
  • 82
    • 84859448265 scopus 로고    scopus 로고
    • Mitofusin 2 (Mfn2) links mitochondrial and endoplasmic reticulum function with insulin signaling and is essential for normal glucose homeostasis
    • Sebastian, D., Hernandez-Alvarez, M. I., Segales, J., Sorianello, E., Munoz, J. P., Sala, D., et al. (2012). Mitofusin 2 (Mfn2) links mitochondrial and endoplasmic reticulum function with insulin signaling and is essential for normal glucose homeostasis. Proc. Natl. Acad. Sci. U.S.A. 109, 5523-5528. doi: 10.1073/pnas.1108220109
    • (2012) Proc. Natl. Acad. Sci. U.S.A , vol.109 , pp. 5523-5528
    • Sebastian, D.1    Hernandez-Alvarez, M.I.2    Segales, J.3    Sorianello, E.4    Munoz, J.P.5    Sala, D.6
  • 83
    • 12744259923 scopus 로고    scopus 로고
    • Regulation of pyruvate dehydrogenase activity and citric acid cycle intermediates during high cardiac power generation
    • Sharma, N., Okere, I. C., Brunengraber, D. Z., Mcelfresh, T. A., King, K. L., Sterk, J. P., et al. (2005). Regulation of pyruvate dehydrogenase activity and citric acid cycle intermediates during high cardiac power generation. J. Physiol. 562, 593-603. doi: 10.1113/jphysiol.2004.075713
    • (2005) J. Physiol , vol.562 , pp. 593-603
    • Sharma, N.1    Okere, I.C.2    Brunengraber, D.Z.3    Mcelfresh, T.A.4    King, K.L.5    Sterk, J.P.6
  • 84
    • 56349133547 scopus 로고    scopus 로고
    • Positioning mitochondrial plasticity within cellular signaling cascades
    • Soubannier, V., and Mcbride, H. M. (2009). Positioning mitochondrial plasticity within cellular signaling cascades. Biochim. Biophys. Acta 1793, 154-170. doi: 10.1016/j.bbamcr.2008.07.008
    • (2009) Biochim. Biophys. Acta , vol.1793 , pp. 154-170
    • Soubannier, V.1    Mcbride, H.M.2
  • 85
    • 77955635790 scopus 로고    scopus 로고
    • Fatty acid oxidation and malonyl-CoA decarboxylase in the vascular remodeling of pulmonary hypertension
    • Sutendra, G., Bonnet, S., Rochefort, G., Haromy, A., Folmes, K. D., Lopaschuk, G. D., et al. (2010). Fatty acid oxidation and malonyl-CoA decarboxylase in the vascular remodeling of pulmonary hypertension. Sci. Transl. Med. 2, 44ra58. doi: 10.1126/scitranslmed.3001327
    • (2010) Sci. Transl. Med , vol.2 , pp. 44ra58
    • Sutendra, G.1    Bonnet, S.2    Rochefort, G.3    Haromy, A.4    Folmes, K.D.5    Lopaschuk, G.D.6
  • 86
    • 79959464127 scopus 로고    scopus 로고
    • The role of Nogo and the mitochondria-endoplasmic reticulum unit in pulmonary hypertension
    • Sutendra, G., Dromparis, P., Wright, P., Bonnet, S., Haromy, A., Hao, Z., et al. (2011). The role of Nogo and the mitochondria-endoplasmic reticulum unit in pulmonary hypertension. Sci. Transl. Med. 3, 88ra55. doi: 10.1126/scitranslmed.3002194
    • (2011) Sci. Transl. Med , vol.3 , pp. 55-88
    • Sutendra, G.1    Dromparis, P.2    Wright, P.3    Bonnet, S.4    Haromy, A.5    Hao, Z.6
  • 87
    • 82855171080 scopus 로고    scopus 로고
    • Multi-Link Vision stent vs. first-generation drug-eluting stents: systematic review and meta-analysis
    • Testa, L., Latini, R. A., Pizzocri, S., Lanotte, S., Agnifili, M., Laudisa, M. L., et al. (2011). Multi-Link Vision stent vs. first-generation drug-eluting stents: systematic review and meta-analysis. QJM 104, 1025-1034. doi: 10.1093/qjmed/hcr138
    • (2011) QJM , vol.104 , pp. 1025-1034
    • Testa, L.1    Latini, R.A.2    Pizzocri, S.3    Lanotte, S.4    Agnifili, M.5    Laudisa, M.L.6
  • 88
    • 84896871426 scopus 로고    scopus 로고
    • MAM (mitochondria-associated membranes) in mammalian cells: lipids and beyond
    • Vance, J. E. (2014). MAM (mitochondria-associated membranes) in mammalian cells: lipids and beyond. Biochim. Biophys. Acta 1841, 595-609. doi: 10.1016/j.bbalip.2013.11.014
    • (2014) Biochim. Biophys. Acta , vol.1841 , pp. 595-609
    • Vance, J.E.1
  • 89
    • 66249108601 scopus 로고    scopus 로고
    • Understanding the Warburg effect: the metabolic requirements of cell proliferation
    • Vander Heiden, M. G., Cantley, L. C., and Thompson, C. B. (2009). Understanding the Warburg effect: the metabolic requirements of cell proliferation. Science 324, 1029-1033. doi: 10.1126/science.1160809
    • (2009) Science , vol.324 , pp. 1029-1033
    • Vander Heiden, M.G.1    Cantley, L.C.2    Thompson, C.B.3
  • 90
    • 0035380462 scopus 로고    scopus 로고
    • Bcl-xL promotes the open configuration of the voltage-dependent anion channel and metabolite passage through the outer mitochondrial membrane
    • Vander Heiden, M. G., Li, X. X., Gottleib, E., Hill, R. B., Thompson, C. B., and Colombini, M. (2001). Bcl-xL promotes the open configuration of the voltage-dependent anion channel and metabolite passage through the outer mitochondrial membrane. J. Biol. Chem. 276, 19414-19419. doi: 10.1074/jbc.M101590200
    • (2001) J. Biol. Chem , vol.276 , pp. 19414-19419
    • Vander Heiden, M.G.1    Li, X.X.2    Gottleib, E.3    Hill, R.B.4    Thompson, C.B.5    Colombini, M.6
  • 91
    • 21644459951 scopus 로고    scopus 로고
    • Structure and function of poly(ADP-ribose) polymerase-1: role in oxidative stress-related pathologies
    • Virag, L. (2005). Structure and function of poly(ADP-ribose) polymerase-1: role in oxidative stress-related pathologies. Curr. Vasc. Pharmacol. 3, 209-214. doi: 10.2174/1570161054368625
    • (2005) Curr. Vasc. Pharmacol , vol.3 , pp. 209-214
    • Virag, L.1
  • 92
    • 70349944660 scopus 로고    scopus 로고
    • The dynamin-related GTPase Drp1 is required for embryonic and brain development in mice
    • Wakabayashi, J., Zhang, Z., Wakabayashi, N., Tamura, Y., Fukaya, M., Kensler, T. W., et al. (2009). The dynamin-related GTPase Drp1 is required for embryonic and brain development in mice. J. Cell Biol. 186, 805-816. doi: 10.1083/jcb.200903065
    • (2009) J. Cell Biol , vol.186 , pp. 805-816
    • Wakabayashi, J.1    Zhang, Z.2    Wakabayashi, N.3    Tamura, Y.4    Fukaya, M.5    Kensler, T.W.6
  • 93
    • 10044229348 scopus 로고    scopus 로고
    • Vascular smooth muscle cell proliferation is dependent upon upregulation of mitochondrial transcription factor A (mtTFA) expression in injured rat carotid artery
    • Yoshida, T., Azuma, H., Aihara, K., Fujimura, M., Akaike, M., Mitsui, T., et al. (2005). Vascular smooth muscle cell proliferation is dependent upon upregulation of mitochondrial transcription factor A (mtTFA) expression in injured rat carotid artery. Atherosclerosis 178, 39-47. doi: 10.1016/j.atherosclerosis.2004.08.029
    • (2005) Atherosclerosis , vol.178 , pp. 39-47
    • Yoshida, T.1    Azuma, H.2    Aihara, K.3    Fujimura, M.4    Akaike, M.5    Mitsui, T.6
  • 94
    • 84906794354 scopus 로고    scopus 로고
    • Mitochondrial DNA damage and atherosclerosis
    • Yu, E. P., and Bennett, M. R. (2014). Mitochondrial DNA damage and atherosclerosis. Trends Endocrinol. Metab. 25, 481-487. doi: 10.1016/j.tem.2014.06.008
    • (2014) Trends Endocrinol. Metab , vol.25 , pp. 481-487
    • Yu, E.P.1    Bennett, M.R.2
  • 95
    • 84902252468 scopus 로고    scopus 로고
    • Drp1 loss-of-function reduces cardiomyocyte oxygen-dependence protecting the heart from ischemia-reperfusion injury
    • Zepeda, R., Kuzmicic, J., Parra, V., Troncoso, R., Pennanen, C., Riquelme, J. A., et al. (2014). Drp1 loss-of-function reduces cardiomyocyte oxygen-dependence protecting the heart from ischemia-reperfusion injury. J. Cardiovasc. Pharmacol. 63, 477-487. doi: 10.1097/FJC.0000000000000071
    • (2014) J. Cardiovasc. Pharmacol , vol.63 , pp. 477-487
    • Zepeda, R.1    Kuzmicic, J.2    Parra, V.3    Troncoso, R.4    Pennanen, C.5    Riquelme, J.A.6
  • 96
    • 77954266957 scopus 로고    scopus 로고
    • Mutation of the protein kinase A phosphorylation site influences the anti-proliferative activity of mitofusin 2
    • Zhou, W., Chen, K. H., Cao, W., Zeng, J., Liao, H., Zhao, L., et al. (2010). Mutation of the protein kinase A phosphorylation site influences the anti-proliferative activity of mitofusin 2. Atherosclerosis 211, 216-223. doi: 10.1016/j.atherosclerosis.2010.02.012
    • (2010) Atherosclerosis , vol.211 , pp. 216-223
    • Zhou, W.1    Chen, K.H.2    Cao, W.3    Zeng, J.4    Liao, H.5    Zhao, L.6
  • 97
    • 77955276765 scopus 로고    scopus 로고
    • Mitochondrial fusion proteins: dual regulators of morphology and metabolism
    • Zorzano, A., Liesa, M., Sebastian, D., Segales, J., and Palacin, M. (2010). Mitochondrial fusion proteins: dual regulators of morphology and metabolism. Semin. Cell Dev. Biol. 21, 566-574. doi: 10.1016/j.semcdb.2010.01.002
    • (2010) Semin. Cell Dev. Biol , vol.21 , pp. 566-574
    • Zorzano, A.1    Liesa, M.2    Sebastian, D.3    Segales, J.4    Palacin, M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.