Mitochondrial fission is required for cardiomyocyte hypertrophy mediated by a Ca2+-calcineurin signaling pathway

Journal of Cell Science

Volumn 127, Issue 12, 2014, Pages 2659-2671

  Pennanen, Christian ^a,b   Parra, Valentina ^a,b,c   López Crisosto, Camila ^a,b   Morales, Pablo E ^a,b   del Campo, Andrea ^a,b   Gutierrez, Tomás ^a,b   Rivera Mejías, Pablo ^a,b   Kuzmicic, Jovan ^a,b   Chiong, Mario ^a,b   Zorzano, Antonio ^d,e,f   Rothermel, Beverly A ^c   Lavandero, Sergio ^a,b,c  

^a University of Chile   (Chile)

^b UNIVERSITY OF CHILE   (Chile)

^c UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^d INSTITUTE FOR RESEARCH IN BIOMEDICINE   (Spain)

^e UNIVERSITY OF BARCELONA   (Spain)

^f INSTITUTO DE SALUD CARLOS III   (Spain)

Author keywords

Calcineurin; Cardiac hypertrophy; Drp1; Metabolism; Mitochondrial fission; Norepinephrine

Indexed keywords

ADENOVIRUS VECTOR; ALPHA 1 ADRENERGIC RECEPTOR; ASMFN2 PROTEIN; CALCINEURIN; CALCIUM ION; DRP1K38A PROTEIN; DYNAMIN RELATED PROTEIN 1; HYBRID PROTEIN; MITOCHONDRIAL PROTEIN; NORADRENALIN; UNCLASSIFIED DRUG; ALPHA ADRENERGIC RECEPTOR STIMULATING AGENT; CALCIUM; DRP1 PROTEIN, RAT; DYNAMIN; MEMBRANE PROTEIN; MITOFUSIN 2 PROTEIN, RAT;

ANIMAL CELL; ANIMAL MODEL; ANTISENSE VECTOR; ARTICLE; CELL MIGRATION; CONTROLLED STUDY; CYTOPLASM; DISORDERS OF MITOCHONDRIAL FUNCTIONS; ENZYME ACTIVATION; GROWTH INHIBITION; HEART CELL CULTURE; HEART MITOCHONDRION; HEART MUSCLE CELL; HEART VENTRICLE HYPERTROPHY; MITOCHONDRIAL DYNAMICS; MITOCHONDRIAL FISSION; MITOCHONDRIAL VOLUME; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; RAT; SIGNAL TRANSDUCTION; STIMULUS RESPONSE; ANIMAL; CALCIUM SIGNALING; CARDIOMEGALY; CELL CULTURE; GENETICS; HYPERTROPHY; METABOLISM; PHYSIOLOGY; PROTEIN TRANSPORT; SPRAGUE DAWLEY RAT;

ADRENERGIC ALPHA-AGONISTS; ANIMALS; CALCINEURIN; CALCIUM; CALCIUM SIGNALING; CARDIOMEGALY; CELLS, CULTURED; DYNAMINS; HYPERTROPHY; MEMBRANE PROTEINS; MITOCHONDRIA, HEART; MITOCHONDRIAL DYNAMICS; MITOCHONDRIAL PROTEINS; MYOCYTES, CARDIAC; NOREPINEPHRINE; PROTEIN TRANSPORT; RATS, SPRAGUE-DAWLEY; RECEPTORS, ADRENERGIC, ALPHA-1;

EID: 84902455654     PISSN: 00219533     EISSN: 14779137     Source Type: Journal    
DOI: 10.1242/jcs.139394     Document Type: Article

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