-
1
-
-
0035856949
-
Insulin signalling and the regulation of glucose and lipid metabolism
-
Saltiel A.R., and Kahn C.R. Insulin signalling and the regulation of glucose and lipid metabolism. Nature 414 (2001) 799-806
-
(2001)
Nature
, vol.414
, pp. 799-806
-
-
Saltiel, A.R.1
Kahn, C.R.2
-
2
-
-
33244481462
-
Ser/Thr phosphorylation of IRS proteins: a molecular basis for insulin resistance
-
Zick Y. Ser/Thr phosphorylation of IRS proteins: a molecular basis for insulin resistance. Sci. STKE 2005 (2005) pe4
-
(2005)
Sci. STKE
, vol.2005
-
-
Zick, Y.1
-
3
-
-
0036149984
-
Molecular mechanism of insulin-induced degradation of insulin receptor substrate 1
-
Zhande R., Mitchell J.J., Wu J., and Sun X.J. Molecular mechanism of insulin-induced degradation of insulin receptor substrate 1. Mol. Cell. Biol. 22 (2002) 1016-1026
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 1016-1026
-
-
Zhande, R.1
Mitchell, J.J.2
Wu, J.3
Sun, X.J.4
-
4
-
-
0035971065
-
Protein-tyrosine phosphatase-1B negatively regulates insulin signaling in l6 myocytes and Fao hepatoma cells
-
Egawa K., Maegawa H., Shimizu S., Morino K., Nishio Y., Bryer-Ash M., Cheung A.T., Kolls J.K., Kikkawa R., and Kashiwagi A. Protein-tyrosine phosphatase-1B negatively regulates insulin signaling in l6 myocytes and Fao hepatoma cells. J. Biol. Chem. 276 (2001) 10207-10211
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 10207-10211
-
-
Egawa, K.1
Maegawa, H.2
Shimizu, S.3
Morino, K.4
Nishio, Y.5
Bryer-Ash, M.6
Cheung, A.T.7
Kolls, J.K.8
Kikkawa, R.9
Kashiwagi, A.10
-
5
-
-
33748657133
-
PTEN and SHIP2 phosphoinositide phosphatases as negative regulators of insulin signalling
-
Vinciguerra M., and Foti M. PTEN and SHIP2 phosphoinositide phosphatases as negative regulators of insulin signalling. Arch. Physiol. Biochem. 112 (2006) 89-104
-
(2006)
Arch. Physiol. Biochem.
, vol.112
, pp. 89-104
-
-
Vinciguerra, M.1
Foti, M.2
-
6
-
-
4344614649
-
Regulation of insulin action by ceramide: dual mechanisms linking ceramide accumulation to the inhibition of Akt/protein kinase B
-
Stratford S., Hoehn K.L., Liu F., and Summers S.A. Regulation of insulin action by ceramide: dual mechanisms linking ceramide accumulation to the inhibition of Akt/protein kinase B. J. Biol. Chem. 279 (2004) 36608-36615
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 36608-36615
-
-
Stratford, S.1
Hoehn, K.L.2
Liu, F.3
Summers, S.A.4
-
7
-
-
27144450970
-
Insulin-sensitive protein kinases (atypical protein kinase C and protein kinase B/Akt): actions and defects in obesity and type II diabetes
-
Farese R.V., Sajan M.P., and Standaert M.L. Insulin-sensitive protein kinases (atypical protein kinase C and protein kinase B/Akt): actions and defects in obesity and type II diabetes. Exp. Biol. Med. (Maywood) 230 (2005) 593-605
-
(2005)
Exp. Biol. Med. (Maywood)
, vol.230
, pp. 593-605
-
-
Farese, R.V.1
Sajan, M.P.2
Standaert, M.L.3
-
8
-
-
12344305124
-
Mitochondrial dysfunction and type 2 diabetes
-
Lowell B.B., and Shulman G.I. Mitochondrial dysfunction and type 2 diabetes. Science 307 (2005) 384-387
-
(2005)
Science
, vol.307
, pp. 384-387
-
-
Lowell, B.B.1
Shulman, G.I.2
-
9
-
-
0038025371
-
Mitochondrial dysfunction in the elderly: possible role in insulin resistance
-
Petersen K.F., Befroy D., Dufour S., Dziura J., Ariyan C., Rothman D.L., DiPietro L., Cline G.W., and Shulman G.I. Mitochondrial dysfunction in the elderly: possible role in insulin resistance. Science 300 (2003) 1140-1142
-
(2003)
Science
, vol.300
, pp. 1140-1142
-
-
Petersen, K.F.1
Befroy, D.2
Dufour, S.3
Dziura, J.4
Ariyan, C.5
Rothman, D.L.6
DiPietro, L.7
Cline, G.W.8
Shulman, G.I.9
-
10
-
-
41949114990
-
Role of mitochondrial dysfunction in insulin resistance
-
Kim J.A., Wei Y., and Sowers J.R. Role of mitochondrial dysfunction in insulin resistance. Circ. Res. 102 (2008) 401-414
-
(2008)
Circ. Res.
, vol.102
, pp. 401-414
-
-
Kim, J.A.1
Wei, Y.2
Sowers, J.R.3
-
11
-
-
0034979379
-
Depletion of mitochondrial DNA alters glucose metabolism in SK-Hep1 cells
-
Park K.S., Nam K.J., Kim J.W., Lee Y.B., Han C.Y., Jeong J.K., Lee H.K., and Pak Y.K. Depletion of mitochondrial DNA alters glucose metabolism in SK-Hep1 cells. Am. J. Physiol. Endocrinol. Metab. 280 (2001) E1007-E1014
-
(2001)
Am. J. Physiol. Endocrinol. Metab.
, vol.280
-
-
Park, K.S.1
Nam, K.J.2
Kim, J.W.3
Lee, Y.B.4
Han, C.Y.5
Jeong, J.K.6
Lee, H.K.7
Pak, Y.K.8
-
12
-
-
15444375759
-
Depletion of mitochondrial DNA causes impaired glucose utilization and insulin resistance in L6 GLUT4myc myocytes
-
Park S.Y., Choi G.H., Choi H.I., Ryu J., Jung C.Y., and Lee W. Depletion of mitochondrial DNA causes impaired glucose utilization and insulin resistance in L6 GLUT4myc myocytes. J. Biol. Chem. 280 (2005) 9855-9864
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 9855-9864
-
-
Park, S.Y.1
Choi, G.H.2
Choi, H.I.3
Ryu, J.4
Jung, C.Y.5
Lee, W.6
-
13
-
-
12144275294
-
Deficiency of subsarcolemmal mitochondria in obesity and type 2 diabetes
-
Ritov V.B., Menshikova E.V., He J., Ferrell R.E., Goodpaster B.H., and Kelley D.E. Deficiency of subsarcolemmal mitochondria in obesity and type 2 diabetes. Diabetes 54 (2005) 8-14
-
(2005)
Diabetes
, vol.54
, pp. 8-14
-
-
Ritov, V.B.1
Menshikova, E.V.2
He, J.3
Ferrell, R.E.4
Goodpaster, B.H.5
Kelley, D.E.6
-
14
-
-
33644821858
-
Mitochondria are impaired in the adipocytes of type 2 diabetic mice
-
Choo H.J., Kim J.H., Kwon O.B., Lee C.S., Mun J.Y., Han S.S., Yoon Y.S., Yoon G., Choi K.M., and Ko Y.G. Mitochondria are impaired in the adipocytes of type 2 diabetic mice. Diabetologia 49 (2006) 784-791
-
(2006)
Diabetologia
, vol.49
, pp. 784-791
-
-
Choo, H.J.1
Kim, J.H.2
Kwon, O.B.3
Lee, C.S.4
Mun, J.Y.5
Han, S.S.6
Yoon, Y.S.7
Yoon, G.8
Choi, K.M.9
Ko, Y.G.10
-
15
-
-
0035936802
-
Atherosclerosis. the road ahead
-
Glass C.K., and Witztum J.L. Atherosclerosis. the road ahead. Cell 104 (2001) 503-516
-
(2001)
Cell
, vol.104
, pp. 503-516
-
-
Glass, C.K.1
Witztum, J.L.2
-
16
-
-
0033621455
-
Oxidation-dependent effects of oxidized LDL: proliferation or cell death
-
Han C.Y., and Pak Y.K. Oxidation-dependent effects of oxidized LDL: proliferation or cell death. Exp. Mol. Med. 31 (1999) 165-173
-
(1999)
Exp. Mol. Med.
, vol.31
, pp. 165-173
-
-
Han, C.Y.1
Pak, Y.K.2
-
17
-
-
0034664943
-
Role of endocytosis in the transactivation of nuclear factor-kappaB by oxidized low-density lipoprotein
-
Han C.Y., Park S.Y., and Pak Y.K. Role of endocytosis in the transactivation of nuclear factor-kappaB by oxidized low-density lipoprotein. Biochem. J. 350 Pt. 3 (2000) 829-837
-
(2000)
Biochem. J.
, vol.350
, Issue.PART 3
, pp. 829-837
-
-
Han, C.Y.1
Park, S.Y.2
Pak, Y.K.3
-
18
-
-
0029908016
-
Expression of a constitutively active Akt Ser/Thr kinase in 3T3-L1 adipocytes stimulates glucose uptake and glucose transporter 4 translocation
-
Kohn A.D., Summers S.A., Birnbaum M.J., and Roth R.A. Expression of a constitutively active Akt Ser/Thr kinase in 3T3-L1 adipocytes stimulates glucose uptake and glucose transporter 4 translocation. J. Biol. Chem. 271 (1996) 31372-31378
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 31372-31378
-
-
Kohn, A.D.1
Summers, S.A.2
Birnbaum, M.J.3
Roth, R.A.4
-
19
-
-
0346433989
-
Complex II defect via down-regulation of iron-sulfur subunit induces mitochondrial dysfunction and cell cycle delay in iron chelation-induced senescence-associated growth arrest
-
Yoon Y.S., Byun H.O., Cho H., Kim B.K., and Yoon G. Complex II defect via down-regulation of iron-sulfur subunit induces mitochondrial dysfunction and cell cycle delay in iron chelation-induced senescence-associated growth arrest. J. Biol. Chem. 278 (2003) 51577-51586
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 51577-51586
-
-
Yoon, Y.S.1
Byun, H.O.2
Cho, H.3
Kim, B.K.4
Yoon, G.5
-
20
-
-
44949185670
-
Analysis of mitochondrial function in situ in permeabilized muscle fibers, tissues and cells
-
Kuznetsov A.V., Veksler V., Gellerich F.N., Saks V., Margreiter R., and Kunz W.S. Analysis of mitochondrial function in situ in permeabilized muscle fibers, tissues and cells. Nat. Protoc. 3 (2008) 965-976
-
(2008)
Nat. Protoc.
, vol.3
, pp. 965-976
-
-
Kuznetsov, A.V.1
Veksler, V.2
Gellerich, F.N.3
Saks, V.4
Margreiter, R.5
Kunz, W.S.6
-
21
-
-
0030000851
-
Activation of LDL receptor gene expression in HepG2 cells by hepatocyte growth factor
-
Pak Y.K., Kanuck M.P., Berrios D., Briggs M.R., Cooper A.D., and Ellsworth J.L. Activation of LDL receptor gene expression in HepG2 cells by hepatocyte growth factor. J. Lipid Res. 37 (1996) 985-998
-
(1996)
J. Lipid Res.
, vol.37
, pp. 985-998
-
-
Pak, Y.K.1
Kanuck, M.P.2
Berrios, D.3
Briggs, M.R.4
Cooper, A.D.5
Ellsworth, J.L.6
-
22
-
-
0035823584
-
The orphan nuclear receptor small heterodimer partner as a novel coregulator of nuclear factor-kappa b in oxidized low density lipoprotein-treated macrophage cell line RAW 264.7
-
Kim Y.S., Han C.Y., Kim S.W., Kim J.H., Lee S.K., Jung D.J., Park S.Y., Kang H., Choi H.S., Lee J.W., and Pak Y.K. The orphan nuclear receptor small heterodimer partner as a novel coregulator of nuclear factor-kappa b in oxidized low density lipoprotein-treated macrophage cell line RAW 264.7. J. Biol. Chem. 276 (2001) 33736-33740
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 33736-33740
-
-
Kim, Y.S.1
Han, C.Y.2
Kim, S.W.3
Kim, J.H.4
Lee, S.K.5
Jung, D.J.6
Park, S.Y.7
Kang, H.8
Choi, H.S.9
Lee, J.W.10
Pak, Y.K.11
-
23
-
-
2442485899
-
Overexpression of uncoupling protein 2 in THP1 monocytes inhibits beta2 integrin-mediated firm adhesion and transendothelial migration
-
Ryu J.W., Hong K.H., Maeng J.H., Kim J.B., Ko J., Park J.Y., Lee K.U., Hong M.K., Park S.W., Kim Y.H., and Han K.H. Overexpression of uncoupling protein 2 in THP1 monocytes inhibits beta2 integrin-mediated firm adhesion and transendothelial migration. Arterioscler. Thromb. Vasc. Biol. 24 (2004) 864-870
-
(2004)
Arterioscler. Thromb. Vasc. Biol.
, vol.24
, pp. 864-870
-
-
Ryu, J.W.1
Hong, K.H.2
Maeng, J.H.3
Kim, J.B.4
Ko, J.5
Park, J.Y.6
Lee, K.U.7
Hong, M.K.8
Park, S.W.9
Kim, Y.H.10
Han, K.H.11
-
24
-
-
67349122064
-
Resveratrol inhibits the mTOR mitogenic signaling evoked by oxidized LDL in smooth muscle cells
-
Brito P.M., Devillard R., Negre-Salvayre A., Almeida L.M., Dinis T.C., Salvayre R., and Auge N. Resveratrol inhibits the mTOR mitogenic signaling evoked by oxidized LDL in smooth muscle cells. Atherosclerosis 205 (2008) 126-134
-
(2008)
Atherosclerosis
, vol.205
, pp. 126-134
-
-
Brito, P.M.1
Devillard, R.2
Negre-Salvayre, A.3
Almeida, L.M.4
Dinis, T.C.5
Salvayre, R.6
Auge, N.7
-
25
-
-
0035654579
-
Oxidized low density lipoprotein inhibits macrophage apoptosis through activation of the PI 3-kinase/PKB pathway
-
Hundal R.S., Salh B.S., Schrader J.W., Gomez-Munoz A., Duronio V., and Steinbrecher U.P. Oxidized low density lipoprotein inhibits macrophage apoptosis through activation of the PI 3-kinase/PKB pathway. J. Lipid Res. 42 (2001) 1483-1491
-
(2001)
J. Lipid Res.
, vol.42
, pp. 1483-1491
-
-
Hundal, R.S.1
Salh, B.S.2
Schrader, J.W.3
Gomez-Munoz, A.4
Duronio, V.5
Steinbrecher, U.P.6
-
26
-
-
33744807726
-
Oxidized low density lipoprotein impairs endothelial progenitor cells by regulation of endothelial nitric oxide synthase
-
Ma F.X., Zhou B., Chen Z., Ren Q., Lu S.H., Sawamura T., and Han Z.C. Oxidized low density lipoprotein impairs endothelial progenitor cells by regulation of endothelial nitric oxide synthase. J. Lipid Res. 47 (2006) 1227-1237
-
(2006)
J. Lipid Res.
, vol.47
, pp. 1227-1237
-
-
Ma, F.X.1
Zhou, B.2
Chen, Z.3
Ren, Q.4
Lu, S.H.5
Sawamura, T.6
Han, Z.C.7
-
27
-
-
0033681149
-
Chronic systemic pesticide exposure reproduces features of Parkinson's disease
-
Betarbet R., Sherer T.B., MacKenzie G., Garcia-Osuna M., Panov A.V., and Greenamyre J.T. Chronic systemic pesticide exposure reproduces features of Parkinson's disease. Nat. Neurosci. 3 (2000) 1301-1306
-
(2000)
Nat. Neurosci.
, vol.3
, pp. 1301-1306
-
-
Betarbet, R.1
Sherer, T.B.2
MacKenzie, G.3
Garcia-Osuna, M.4
Panov, A.V.5
Greenamyre, J.T.6
-
28
-
-
0028109345
-
Comparison of mitochondrial morphology, mitochondrial DNA content, and cell viability in cultured cells treated with three anti-human immunodeficiency virus dideoxynucleosides
-
Medina D.J., Tsai C.H., Hsiung G.D., and Cheng Y.C. Comparison of mitochondrial morphology, mitochondrial DNA content, and cell viability in cultured cells treated with three anti-human immunodeficiency virus dideoxynucleosides. Antimicrob. Agents Chemother. 38 (1994) 1824-1828
-
(1994)
Antimicrob. Agents Chemother.
, vol.38
, pp. 1824-1828
-
-
Medina, D.J.1
Tsai, C.H.2
Hsiung, G.D.3
Cheng, Y.C.4
-
29
-
-
40449112930
-
Large-scale chemical dissection of mitochondrial function
-
Wagner B.K., Kitami T., Gilbert T.J., Peck D., Ramanathan A., Schreiber S.L., Golub T.R., and Mootha V.K. Large-scale chemical dissection of mitochondrial function. Nat. Biotechnol. 26 (2008) 343-351
-
(2008)
Nat. Biotechnol.
, vol.26
, pp. 343-351
-
-
Wagner, B.K.1
Kitami, T.2
Gilbert, T.J.3
Peck, D.4
Ramanathan, A.5
Schreiber, S.L.6
Golub, T.R.7
Mootha, V.K.8
-
30
-
-
12844281251
-
AMPK, the metabolic syndrome and cancer
-
Luo Z., Saha A.K., Xiang X., and Ruderman N.B. AMPK, the metabolic syndrome and cancer. Trends Pharmacol. Sci. 26 (2005) 69-76
-
(2005)
Trends Pharmacol. Sci.
, vol.26
, pp. 69-76
-
-
Luo, Z.1
Saha, A.K.2
Xiang, X.3
Ruderman, N.B.4
-
31
-
-
33745213627
-
AMPK and cell proliferation-AMPK as a therapeutic target for atherosclerosis and cancer
-
Motoshima H., Goldstein B.J., Igata M., and Araki E. AMPK and cell proliferation-AMPK as a therapeutic target for atherosclerosis and cancer. J. Physiol. 574 (2006) 63-71
-
(2006)
J. Physiol.
, vol.574
, pp. 63-71
-
-
Motoshima, H.1
Goldstein, B.J.2
Igata, M.3
Araki, E.4
-
32
-
-
10944247187
-
The AMP-activated protein kinase pathway-new players upstream and downstream
-
Hardie D.G. The AMP-activated protein kinase pathway-new players upstream and downstream. J. Cell. Sci. 117 (2004) 5479-5487
-
(2004)
J. Cell. Sci.
, vol.117
, pp. 5479-5487
-
-
Hardie, D.G.1
-
33
-
-
33745684376
-
AMPK activation restores the stimulation of glucose uptake in an in vitro model of insulin-resistant cardiomyocytes via the activation of protein kinase B
-
Bertrand L., Ginion A., Beauloye C., Hebert A.D., Guigas B., Hue L., and Vanoverschelde J.L. AMPK activation restores the stimulation of glucose uptake in an in vitro model of insulin-resistant cardiomyocytes via the activation of protein kinase B. Am. J. Physiol. Heart Circ. Physiol. 291 (2006) H239-H250
-
(2006)
Am. J. Physiol. Heart Circ. Physiol.
, vol.291
-
-
Bertrand, L.1
Ginion, A.2
Beauloye, C.3
Hebert, A.D.4
Guigas, B.5
Hue, L.6
Vanoverschelde, J.L.7
-
34
-
-
42149107512
-
Role of smooth muscle cells in the initiation and early progression of atherosclerosis
-
Doran A.C., Meller N., and McNamara C.A. Role of smooth muscle cells in the initiation and early progression of atherosclerosis. Arterioscler. Thromb. Vasc. Biol. 28 (2008) 812-819
-
(2008)
Arterioscler. Thromb. Vasc. Biol.
, vol.28
, pp. 812-819
-
-
Doran, A.C.1
Meller, N.2
McNamara, C.A.3
|