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Volumn 1800, Issue 3, 2010, Pages 275-281

Mitochondrial dysfunction enhances the migration of vascular smooth muscles cells via suppression of Akt phosphorylation

Author keywords

Akt PKB; Atherosclerosis; Insulin signaling; Mitochondrial dysfunction; oxLDL; VSMC

Indexed keywords

ADENOSINE TRIPHOSPHATE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; INSULIN; INSULIN RECEPTOR SUBSTRATE 1; INSULIN RECEPTOR SUBSTRATE 2; MESSENGER RNA; OXIDIZED LOW DENSITY LIPOPROTEIN; PROTEIN KINASE B; MITOCHONDRIAL DNA; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); ROTENONE; TRICIRIBINE; ZALCITABINE;

EID: 76749110211     PISSN: 03044165     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbagen.2009.09.005     Document Type: Article
Times cited : (32)

References (34)
  • 1
    • 0035856949 scopus 로고    scopus 로고
    • Insulin signalling and the regulation of glucose and lipid metabolism
    • Saltiel A.R., and Kahn C.R. Insulin signalling and the regulation of glucose and lipid metabolism. Nature 414 (2001) 799-806
    • (2001) Nature , vol.414 , pp. 799-806
    • Saltiel, A.R.1    Kahn, C.R.2
  • 2
    • 33244481462 scopus 로고    scopus 로고
    • Ser/Thr phosphorylation of IRS proteins: a molecular basis for insulin resistance
    • Zick Y. Ser/Thr phosphorylation of IRS proteins: a molecular basis for insulin resistance. Sci. STKE 2005 (2005) pe4
    • (2005) Sci. STKE , vol.2005
    • Zick, Y.1
  • 3
    • 0036149984 scopus 로고    scopus 로고
    • Molecular mechanism of insulin-induced degradation of insulin receptor substrate 1
    • Zhande R., Mitchell J.J., Wu J., and Sun X.J. Molecular mechanism of insulin-induced degradation of insulin receptor substrate 1. Mol. Cell. Biol. 22 (2002) 1016-1026
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 1016-1026
    • Zhande, R.1    Mitchell, J.J.2    Wu, J.3    Sun, X.J.4
  • 5
    • 33748657133 scopus 로고    scopus 로고
    • PTEN and SHIP2 phosphoinositide phosphatases as negative regulators of insulin signalling
    • Vinciguerra M., and Foti M. PTEN and SHIP2 phosphoinositide phosphatases as negative regulators of insulin signalling. Arch. Physiol. Biochem. 112 (2006) 89-104
    • (2006) Arch. Physiol. Biochem. , vol.112 , pp. 89-104
    • Vinciguerra, M.1    Foti, M.2
  • 6
    • 4344614649 scopus 로고    scopus 로고
    • Regulation of insulin action by ceramide: dual mechanisms linking ceramide accumulation to the inhibition of Akt/protein kinase B
    • Stratford S., Hoehn K.L., Liu F., and Summers S.A. Regulation of insulin action by ceramide: dual mechanisms linking ceramide accumulation to the inhibition of Akt/protein kinase B. J. Biol. Chem. 279 (2004) 36608-36615
    • (2004) J. Biol. Chem. , vol.279 , pp. 36608-36615
    • Stratford, S.1    Hoehn, K.L.2    Liu, F.3    Summers, S.A.4
  • 7
    • 27144450970 scopus 로고    scopus 로고
    • Insulin-sensitive protein kinases (atypical protein kinase C and protein kinase B/Akt): actions and defects in obesity and type II diabetes
    • Farese R.V., Sajan M.P., and Standaert M.L. Insulin-sensitive protein kinases (atypical protein kinase C and protein kinase B/Akt): actions and defects in obesity and type II diabetes. Exp. Biol. Med. (Maywood) 230 (2005) 593-605
    • (2005) Exp. Biol. Med. (Maywood) , vol.230 , pp. 593-605
    • Farese, R.V.1    Sajan, M.P.2    Standaert, M.L.3
  • 8
    • 12344305124 scopus 로고    scopus 로고
    • Mitochondrial dysfunction and type 2 diabetes
    • Lowell B.B., and Shulman G.I. Mitochondrial dysfunction and type 2 diabetes. Science 307 (2005) 384-387
    • (2005) Science , vol.307 , pp. 384-387
    • Lowell, B.B.1    Shulman, G.I.2
  • 10
    • 41949114990 scopus 로고    scopus 로고
    • Role of mitochondrial dysfunction in insulin resistance
    • Kim J.A., Wei Y., and Sowers J.R. Role of mitochondrial dysfunction in insulin resistance. Circ. Res. 102 (2008) 401-414
    • (2008) Circ. Res. , vol.102 , pp. 401-414
    • Kim, J.A.1    Wei, Y.2    Sowers, J.R.3
  • 12
    • 15444375759 scopus 로고    scopus 로고
    • Depletion of mitochondrial DNA causes impaired glucose utilization and insulin resistance in L6 GLUT4myc myocytes
    • Park S.Y., Choi G.H., Choi H.I., Ryu J., Jung C.Y., and Lee W. Depletion of mitochondrial DNA causes impaired glucose utilization and insulin resistance in L6 GLUT4myc myocytes. J. Biol. Chem. 280 (2005) 9855-9864
    • (2005) J. Biol. Chem. , vol.280 , pp. 9855-9864
    • Park, S.Y.1    Choi, G.H.2    Choi, H.I.3    Ryu, J.4    Jung, C.Y.5    Lee, W.6
  • 15
    • 0035936802 scopus 로고    scopus 로고
    • Atherosclerosis. the road ahead
    • Glass C.K., and Witztum J.L. Atherosclerosis. the road ahead. Cell 104 (2001) 503-516
    • (2001) Cell , vol.104 , pp. 503-516
    • Glass, C.K.1    Witztum, J.L.2
  • 16
    • 0033621455 scopus 로고    scopus 로고
    • Oxidation-dependent effects of oxidized LDL: proliferation or cell death
    • Han C.Y., and Pak Y.K. Oxidation-dependent effects of oxidized LDL: proliferation or cell death. Exp. Mol. Med. 31 (1999) 165-173
    • (1999) Exp. Mol. Med. , vol.31 , pp. 165-173
    • Han, C.Y.1    Pak, Y.K.2
  • 17
    • 0034664943 scopus 로고    scopus 로고
    • Role of endocytosis in the transactivation of nuclear factor-kappaB by oxidized low-density lipoprotein
    • Han C.Y., Park S.Y., and Pak Y.K. Role of endocytosis in the transactivation of nuclear factor-kappaB by oxidized low-density lipoprotein. Biochem. J. 350 Pt. 3 (2000) 829-837
    • (2000) Biochem. J. , vol.350 , Issue.PART 3 , pp. 829-837
    • Han, C.Y.1    Park, S.Y.2    Pak, Y.K.3
  • 18
    • 0029908016 scopus 로고    scopus 로고
    • Expression of a constitutively active Akt Ser/Thr kinase in 3T3-L1 adipocytes stimulates glucose uptake and glucose transporter 4 translocation
    • Kohn A.D., Summers S.A., Birnbaum M.J., and Roth R.A. Expression of a constitutively active Akt Ser/Thr kinase in 3T3-L1 adipocytes stimulates glucose uptake and glucose transporter 4 translocation. J. Biol. Chem. 271 (1996) 31372-31378
    • (1996) J. Biol. Chem. , vol.271 , pp. 31372-31378
    • Kohn, A.D.1    Summers, S.A.2    Birnbaum, M.J.3    Roth, R.A.4
  • 19
    • 0346433989 scopus 로고    scopus 로고
    • Complex II defect via down-regulation of iron-sulfur subunit induces mitochondrial dysfunction and cell cycle delay in iron chelation-induced senescence-associated growth arrest
    • Yoon Y.S., Byun H.O., Cho H., Kim B.K., and Yoon G. Complex II defect via down-regulation of iron-sulfur subunit induces mitochondrial dysfunction and cell cycle delay in iron chelation-induced senescence-associated growth arrest. J. Biol. Chem. 278 (2003) 51577-51586
    • (2003) J. Biol. Chem. , vol.278 , pp. 51577-51586
    • Yoon, Y.S.1    Byun, H.O.2    Cho, H.3    Kim, B.K.4    Yoon, G.5
  • 20
    • 44949185670 scopus 로고    scopus 로고
    • Analysis of mitochondrial function in situ in permeabilized muscle fibers, tissues and cells
    • Kuznetsov A.V., Veksler V., Gellerich F.N., Saks V., Margreiter R., and Kunz W.S. Analysis of mitochondrial function in situ in permeabilized muscle fibers, tissues and cells. Nat. Protoc. 3 (2008) 965-976
    • (2008) Nat. Protoc. , vol.3 , pp. 965-976
    • Kuznetsov, A.V.1    Veksler, V.2    Gellerich, F.N.3    Saks, V.4    Margreiter, R.5    Kunz, W.S.6
  • 22
    • 0035823584 scopus 로고    scopus 로고
    • The orphan nuclear receptor small heterodimer partner as a novel coregulator of nuclear factor-kappa b in oxidized low density lipoprotein-treated macrophage cell line RAW 264.7
    • Kim Y.S., Han C.Y., Kim S.W., Kim J.H., Lee S.K., Jung D.J., Park S.Y., Kang H., Choi H.S., Lee J.W., and Pak Y.K. The orphan nuclear receptor small heterodimer partner as a novel coregulator of nuclear factor-kappa b in oxidized low density lipoprotein-treated macrophage cell line RAW 264.7. J. Biol. Chem. 276 (2001) 33736-33740
    • (2001) J. Biol. Chem. , vol.276 , pp. 33736-33740
    • Kim, Y.S.1    Han, C.Y.2    Kim, S.W.3    Kim, J.H.4    Lee, S.K.5    Jung, D.J.6    Park, S.Y.7    Kang, H.8    Choi, H.S.9    Lee, J.W.10    Pak, Y.K.11
  • 25
    • 0035654579 scopus 로고    scopus 로고
    • Oxidized low density lipoprotein inhibits macrophage apoptosis through activation of the PI 3-kinase/PKB pathway
    • Hundal R.S., Salh B.S., Schrader J.W., Gomez-Munoz A., Duronio V., and Steinbrecher U.P. Oxidized low density lipoprotein inhibits macrophage apoptosis through activation of the PI 3-kinase/PKB pathway. J. Lipid Res. 42 (2001) 1483-1491
    • (2001) J. Lipid Res. , vol.42 , pp. 1483-1491
    • Hundal, R.S.1    Salh, B.S.2    Schrader, J.W.3    Gomez-Munoz, A.4    Duronio, V.5    Steinbrecher, U.P.6
  • 26
    • 33744807726 scopus 로고    scopus 로고
    • Oxidized low density lipoprotein impairs endothelial progenitor cells by regulation of endothelial nitric oxide synthase
    • Ma F.X., Zhou B., Chen Z., Ren Q., Lu S.H., Sawamura T., and Han Z.C. Oxidized low density lipoprotein impairs endothelial progenitor cells by regulation of endothelial nitric oxide synthase. J. Lipid Res. 47 (2006) 1227-1237
    • (2006) J. Lipid Res. , vol.47 , pp. 1227-1237
    • Ma, F.X.1    Zhou, B.2    Chen, Z.3    Ren, Q.4    Lu, S.H.5    Sawamura, T.6    Han, Z.C.7
  • 28
    • 0028109345 scopus 로고
    • Comparison of mitochondrial morphology, mitochondrial DNA content, and cell viability in cultured cells treated with three anti-human immunodeficiency virus dideoxynucleosides
    • Medina D.J., Tsai C.H., Hsiung G.D., and Cheng Y.C. Comparison of mitochondrial morphology, mitochondrial DNA content, and cell viability in cultured cells treated with three anti-human immunodeficiency virus dideoxynucleosides. Antimicrob. Agents Chemother. 38 (1994) 1824-1828
    • (1994) Antimicrob. Agents Chemother. , vol.38 , pp. 1824-1828
    • Medina, D.J.1    Tsai, C.H.2    Hsiung, G.D.3    Cheng, Y.C.4
  • 31
    • 33745213627 scopus 로고    scopus 로고
    • AMPK and cell proliferation-AMPK as a therapeutic target for atherosclerosis and cancer
    • Motoshima H., Goldstein B.J., Igata M., and Araki E. AMPK and cell proliferation-AMPK as a therapeutic target for atherosclerosis and cancer. J. Physiol. 574 (2006) 63-71
    • (2006) J. Physiol. , vol.574 , pp. 63-71
    • Motoshima, H.1    Goldstein, B.J.2    Igata, M.3    Araki, E.4
  • 32
    • 10944247187 scopus 로고    scopus 로고
    • The AMP-activated protein kinase pathway-new players upstream and downstream
    • Hardie D.G. The AMP-activated protein kinase pathway-new players upstream and downstream. J. Cell. Sci. 117 (2004) 5479-5487
    • (2004) J. Cell. Sci. , vol.117 , pp. 5479-5487
    • Hardie, D.G.1
  • 33
    • 33745684376 scopus 로고    scopus 로고
    • AMPK activation restores the stimulation of glucose uptake in an in vitro model of insulin-resistant cardiomyocytes via the activation of protein kinase B
    • Bertrand L., Ginion A., Beauloye C., Hebert A.D., Guigas B., Hue L., and Vanoverschelde J.L. AMPK activation restores the stimulation of glucose uptake in an in vitro model of insulin-resistant cardiomyocytes via the activation of protein kinase B. Am. J. Physiol. Heart Circ. Physiol. 291 (2006) H239-H250
    • (2006) Am. J. Physiol. Heart Circ. Physiol. , vol.291
    • Bertrand, L.1    Ginion, A.2    Beauloye, C.3    Hebert, A.D.4    Guigas, B.5    Hue, L.6    Vanoverschelde, J.L.7
  • 34
    • 42149107512 scopus 로고    scopus 로고
    • Role of smooth muscle cells in the initiation and early progression of atherosclerosis
    • Doran A.C., Meller N., and McNamara C.A. Role of smooth muscle cells in the initiation and early progression of atherosclerosis. Arterioscler. Thromb. Vasc. Biol. 28 (2008) 812-819
    • (2008) Arterioscler. Thromb. Vasc. Biol. , vol.28 , pp. 812-819
    • Doran, A.C.1    Meller, N.2    McNamara, C.A.3


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