Sleeping Beauty transposon mutagenesis identifies genes that cooperate with mutant Smad4 in gastric cancer development

Proceedings of the National Academy of Sciences of the United States of America

Volumn 113, Issue 14, 2016, Pages E2057-E2065

  Takeda, Haruna ^a,b   Rust, Alistair G ^c,d   Ward, Jerrold M ^a   Yew, Christopher Chin Kuan ^a   Jenkins, Nancy A ^a,e   Copeland, Neal G ^a,e  

^a INSTITUTE OF MOLECULAR AND CELL BIOLOGY   (Singapore)

^b KANAZAWA MEDICAL UNIVERSITY   (Japan)

^c WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

^d INSTITUTE OF CANCER RESEARCH   (United Kingdom)

^e HOUSTON METHODIST RESEARCH INSTITUTE   (United States)

Author keywords

Gastric cancer; SB mutagenesis; Smad4 cooperating genes

Indexed keywords

LDL RECEPTOR RELATED PROTEIN 1B; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN; NF1 PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN; RING FINGER PROTEIN; RING FINGER PROTEIN 43; RNA; SMAD4 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; UBIQUITIN; UNCLASSIFIED DRUG; WNT PROTEIN; CHROMATIN; SLEEPING BEAUTY TRANSPOSASE, HUMAN; SMAD4 PROTEIN, HUMAN; TRANSPOSASE; TRANSPOSON;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL JUNCTION; CHROMATIN; GENE; HUMAN; MOUSE; MUTAGENESIS; MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; STOMACH CANCER; TRANSPOSON; TUMOR GENE; TUMOR SUPPRESSOR GENE; ADHERENS JUNCTION; ANIMAL; GENETICS; KNOCKOUT MOUSE; METABOLISM; ONCOGENE; PATHOLOGY; STOMACH TUMOR;

ADHERENS JUNCTIONS; ANIMALS; CHROMATIN; DNA TRANSPOSABLE ELEMENTS; HUMANS; MICE; MICE, KNOCKOUT; MUTAGENESIS; ONCOGENES; SMAD4 PROTEIN; STOMACH NEOPLASMS; TRANSPOSASES;

EID: 84962625803     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1603223113     Document Type: Article

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