Mutation analysis of large tumor suppressor genes LATS1 and LATS2 supports a tumor suppressor role in human cancer

Protein and Cell

Volumn 6, Issue 1, 2015, Pages 6-11

  Yu, Tian ^a   Bachman, John ^a   Lai, Zhi Chun ^a  

^a PENNSYLVANIA STATE UNIVERSITY   (United States)

Author keywords

cancer genome; hippo signaling; human cancer; LATS1 LATS2

Indexed keywords

AJUBA PROTEIN; AMOTL2 PROTEIN; KIBRA PROTEIN; LCD1 PROTEIN; LCD2 PROTEIN; MOB PROTEIN; MST1 KINASE; MST2 KINASE; PEPTIDES AND PROTEINS; UNCLASSIFIED DRUG; YAP PROTEIN; CARRIER PROTEIN; JUB PROTEIN, MOUSE; KIBRA PROTEIN, MOUSE; LATS1 PROTEIN, HUMAN; LATS2 PROTEIN, HUMAN; LIM PROTEIN; MST2 PROTEIN, MOUSE; PHOSPHOPROTEIN; PHOSPHOTRANSFERASE; PROTEIN BINDING; PROTEIN SERINE THREONINE KINASE; SIGNAL TRANSDUCING ADAPTOR PROTEIN; SPHINGOMYELIN SYNTHASE 1, MOUSE; STK4 PROTEIN, MOUSE; TUMOR SUPPRESSOR PROTEIN; YAP PROTEIN, MOUSE;

ARTICLE; CANCER INHIBITION; CARBOXY TERMINAL SEQUENCE; CARCINOGENESIS; CHROMOSOMAL INSTABILITY; GENE FUNCTION; GENETIC ANALYSIS; LARGE TUMOR SUPPRESSOR GENE 1; LARGE TUMOR SUPPRESSOR GENE 2; MUTATIONAL ANALYSIS; NEOPLASM; NONSENSE MUTATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR GENE; ANIMAL; BIOLOGY; CHEMISTRY; GENETICS; HUMAN; METABOLISM; MOUSE; MUTATION; PATHOLOGY; PHOSPHORYLATION; PROTEIN TERTIARY STRUCTURE; TUMOR GENE;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; CARRIER PROTEINS; COMPUTATIONAL BIOLOGY; GENES, NEOPLASM; HUMANS; LIM DOMAIN PROTEINS; MICE; MUTATION; NEOPLASMS; PHOSPHOPROTEINS; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; PROTEIN-SERINE-THREONINE KINASES; TRANSFERASES (OTHER SUBSTITUTED PHOSPHATE GROUPS); TUMOR SUPPRESSOR PROTEINS;

EID: 84925536941     PISSN: 1674800X     EISSN: 16748018     Source Type: Journal    
DOI: 10.1007/s13238-014-0122-4     Document Type: Article

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