메뉴 건너뛰기




Volumn 13, Issue 1, 2007, Pages 102-110

Inactivation of SMAD4 tumor suppressor gene during gastric carcinoma progression

Author keywords

[No Author keywords available]

Indexed keywords

BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; RNA; SMAD4 PROTEIN;

EID: 33846326893     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-06-1467     Document Type: Article
Times cited : (108)

References (42)
  • 1
    • 0030593038 scopus 로고    scopus 로고
    • DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1
    • Hahn SA, Schutte M, Hoque AT, et al. DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1. Science 1996;271:350-3.
    • (1996) Science , vol.271 , pp. 350-353
    • Hahn, S.A.1    Schutte, M.2    Hoque, A.T.3
  • 2
    • 0037757793 scopus 로고    scopus 로고
    • Role of Smad4 (DPC4) inactivation in human cancer
    • Miyaki M, Kuroki T. Role of Smad4 (DPC4) inactivation in human cancer. Biochem Biophys Res Commun 2003;306:799-804.
    • (2003) Biochem Biophys Res Commun , vol.306 , pp. 799-804
    • Miyaki, M.1    Kuroki, T.2
  • 3
    • 1842481404 scopus 로고    scopus 로고
    • Missense mutation of MADH4: Characterization of the mutational hot spot and functional consequences in human tumors
    • Iacobuzio-Donahue CA, Song J, Parmiagiani G, et al. Missense mutation of MADH4: characterization of the mutational hot spot and functional consequences in human tumors. Clin Cancer Res 2004;10:1597-604.
    • (2004) Clin Cancer Res , vol.10 , pp. 1597-1604
    • Iacobuzio-Donahue, C.A.1    Song, J.2    Parmiagiani, G.3
  • 4
    • 9344223357 scopus 로고    scopus 로고
    • DPC4 gene in various tumor types
    • Schutte M, Hruban RH, Hedrick L, et al. DPC4 gene in various tumor types. Cancer Res 1996;56:2527-30.
    • (1996) Cancer Res , vol.56 , pp. 2527-2530
    • Schutte, M.1    Hruban, R.H.2    Hedrick, L.3
  • 5
    • 0000799313 scopus 로고    scopus 로고
    • DPC4, a candidate tumor suppressor gene, is altered infrequently in head and neck squamous cell carcinoma
    • Kim SK, Fan Y, Papadimitrakopoulou V, et al. DPC4, a candidate tumor suppressor gene, is altered infrequently in head and neck squamous cell carcinoma. Cancer Res 1996;56:2519-21.
    • (1996) Cancer Res , vol.56 , pp. 2519-2521
    • Kim, S.K.1    Fan, Y.2    Papadimitrakopoulou, V.3
  • 6
    • 0030800924 scopus 로고    scopus 로고
    • Comparative mutational analysis of DPC4 (Smad4) in prostatic and colorectal carcinomas
    • MacGrogan D, Pegram M, Slamon D, Bookstein R. Comparative mutational analysis of DPC4 (Smad4) in prostatic and colorectal carcinomas. Oncogene 1997;15:1111-4.
    • (1997) Oncogene , vol.15 , pp. 1111-1114
    • MacGrogan, D.1    Pegram, M.2    Slamon, D.3    Bookstein, R.4
  • 7
    • 8044247811 scopus 로고    scopus 로고
    • Infrequent DPC4 gene mutation in esophageal cancer, gastric cancer and ulcerative colitis-associated neoplasms
    • Lei J, Zou TT, Shi YQ, et al. Infrequent DPC4 gene mutation in esophageal cancer, gastric cancer and ulcerative colitis-associated neoplasms. Oncogene 1996; 13:2459-62.
    • (1996) Oncogene , vol.13 , pp. 2459-2462
    • Lei, J.1    Zou, T.T.2    Shi, Y.Q.3
  • 8
    • 0037103055 scopus 로고    scopus 로고
    • Decreased Smad4 expression in the transforming growth factor-β signaling pathway during progression of esophageal squamous cell carcinoma
    • Fukuchi M, Masuda N, Miyazaki T, et al. Decreased Smad4 expression in the transforming growth factor-β signaling pathway during progression of esophageal squamous cell carcinoma. Cancer 2002;95:737-43.
    • (2002) Cancer , vol.95 , pp. 737-743
    • Fukuchi, M.1    Masuda, N.2    Miyazaki, T.3
  • 9
    • 11144355740 scopus 로고    scopus 로고
    • Loss of BMP2, Smad8, and Smad4 expression in prostate cancer progression
    • Horvath LG, Henshall SM, Kench JG, et al. Loss of BMP2, Smad8, and Smad4 expression in prostate cancer progression. Prostate 2004;59:234-42.
    • (2004) Prostate , vol.59 , pp. 234-242
    • Horvath, L.G.1    Henshall, S.M.2    Kench, J.G.3
  • 10
    • 3042526149 scopus 로고    scopus 로고
    • Utilizing Nottingham Prognostic Index in microarray gene expression profiling of breast carcinomas
    • Miller DV, Leontovich AA, Lingle WL, et al. Utilizing Nottingham Prognostic Index in microarray gene expression profiling of breast carcinomas. Mod Pathol 2004;17:756-64.
    • (2004) Mod Pathol , vol.17 , pp. 756-764
    • Miller, D.V.1    Leontovich, A.A.2    Lingle, W.L.3
  • 11
    • 0036827889 scopus 로고    scopus 로고
    • Restoration of transforming growth factor-β signaling by functional expression of smad4 induces anoikis
    • Ramachandra M, Atencio I, Rahman A, et al. Restoration of transforming growth factor-β signaling by functional expression of smad4 induces anoikis. Cancer Res 2002;62:6045-51
    • (2002) Cancer Res , vol.62 , pp. 6045-6051
    • Ramachandra, M.1    Atencio, I.2    Rahman, A.3
  • 12
    • 0035124190 scopus 로고    scopus 로고
    • Preserved Smad4 expression in the transforming growth factor-β signaling pathway is a favorable prognostic factor in patients with advanced gastric cancer
    • Xiangming C, Natsugoe S, Takao S, et al. Preserved Smad4 expression in the transforming growth factor-β signaling pathway is a favorable prognostic factor in patients with advanced gastric cancer. Clin Cancer Res 2001;7:277-82.
    • (2001) Clin Cancer Res , vol.7 , pp. 277-282
    • Xiangming, C.1    Natsugoe, S.2    Takao, S.3
  • 13
    • 0842327354 scopus 로고    scopus 로고
    • Frequent alterations of Smad signaling in human head and neck squamous cell carcinomas: A tissue microarray analysis
    • Xie W, Bharathy S, Kim D, Haffty BG, Rimm DL, Reiss M. Frequent alterations of Smad signaling in human head and neck squamous cell carcinomas: a tissue microarray analysis. Oncol Res 2003;14:61-73.
    • (2003) Oncol Res , vol.14 , pp. 61-73
    • Xie, W.1    Bharathy, S.2    Kim, D.3    Haffty, B.G.4    Rimm, D.L.5    Reiss, M.6
  • 14
    • 0034684287 scopus 로고    scopus 로고
    • The 18q21 region in colorectal and pancreatic cancer: Independent loss of DCC and DPC4 expression
    • Barbera VM, Martin M, Marinoso L, et al. The 18q21 region in colorectal and pancreatic cancer: independent loss of DCC and DPC4 expression. Biochim Biophys Acta 2000;1502:283-96.
    • (2000) Biochim Biophys Acta , vol.1502 , pp. 283-296
    • Barbera, V.M.1    Martin, M.2    Marinoso, L.3
  • 16
    • 0034611611 scopus 로고    scopus 로고
    • Haploid loss of the tumor suppressor Smad4/Dpc4 initiates gastric polyposis and cancer in mice
    • Xu X, Brodie SG, Yang X, et al. Haploid loss of the tumor suppressor Smad4/Dpc4 initiates gastric polyposis and cancer in mice. Oncogene 2000;19:1868-74.
    • (2000) Oncogene , vol.19 , pp. 1868-1874
    • Xu, X.1    Brodie, S.G.2    Yang, X.3
  • 17
    • 0032960181 scopus 로고    scopus 로고
    • Cancer epigenetics comes of age
    • Jones PA, Laird PW. Cancer epigenetics comes of age. Nat Genet 1999;21:163-7.
    • (1999) Nat Genet , vol.21 , pp. 163-167
    • Jones, P.A.1    Laird, P.W.2
  • 20
    • 0030837455 scopus 로고    scopus 로고
    • A structural basis for mutational inactivation of the tumour suppressor Smad4
    • Shi Y, Hata A, Lo RS, Massague J, Pavletich NP. A structural basis for mutational inactivation of the tumour suppressor Smad4. Nature 1997;388:87-93.
    • (1997) Nature , vol.388 , pp. 87-93
    • Shi, Y.1    Hata, A.2    Lo, R.S.3    Massague, J.4    Pavletich, N.P.5
  • 21
    • 20944440516 scopus 로고    scopus 로고
    • SCF(β-TrCP1) controls Smad4 protein stability in pancreatic cancer cells
    • Wan M, Huang J, Jhala NC, et al. SCF(β-TrCP1) controls Smad4 protein stability in pancreatic cancer cells. Am J Pathol 2005;166:1379-92.
    • (2005) Am J Pathol , vol.166 , pp. 1379-1392
    • Wan, M.1    Huang, J.2    Jhala, N.C.3
  • 22
    • 4344619927 scopus 로고    scopus 로고
    • Ubiquitination and proteolysis of cancer-derived Smad4 mutants by SCFSkp2
    • Liang M, Liang YY, Wrighton K, et al. Ubiquitination and proteolysis of cancer-derived Smad4 mutants by SCFSkp2. Mol Cell Biol 2004;24:7524-37.
    • (2004) Mol Cell Biol , vol.24 , pp. 7524-7537
    • Liang, M.1    Liang, Y.Y.2    Wrighton, K.3
  • 23
    • 0034460336 scopus 로고    scopus 로고
    • Transforming growth factor β-independent shuttling of Smad4 between the cytoplasm and nucleus
    • Pierreux CE, Nicolas FJ, Hill CS. Transforming growth factor β-independent shuttling of Smad4 between the cytoplasm and nucleus. Mol Cell Biol 2000;20:9041-54.
    • (2000) Mol Cell Biol , vol.20 , pp. 9041-9054
    • Pierreux, C.E.1    Nicolas, F.J.2    Hill, C.S.3
  • 25
    • 0037462502 scopus 로고    scopus 로고
    • Disruption of transforming growth factor-β signaling in ELF β-spectrin-deficient mice
    • Tang Y, Katuri V, Dillner A, Mishra B, Deng CX, Mishra L. Disruption of transforming growth factor-β signaling in ELF β-spectrin-deficient mice. Science 2003; 299:574-7.
    • (2003) Science , vol.299 , pp. 574-577
    • Tang, Y.1    Katuri, V.2    Dillner, A.3    Mishra, B.4    Deng, C.X.5    Mishra, L.6
  • 26
    • 28544436147 scopus 로고    scopus 로고
    • Inactivation of ELF/ TGF-β signaling in human gastrointestinal cancer
    • Katuri V, Tang Y, Marshall B, et al. Inactivation of ELF/ TGF-β signaling in human gastrointestinal cancer. Oncogene 2005;24:8012-24.
    • (2005) Oncogene , vol.24 , pp. 8012-8024
    • Katuri, V.1    Tang, Y.2    Marshall, B.3
  • 28
    • 33646137574 scopus 로고    scopus 로고
    • Increased expression of sonic hedgehog and altered methylation of its promoter region in gastric cancer and its related lesions
    • Wang LH, Choi YL, Hua XY, et al. Increased expression of sonic hedgehog and altered methylation of its promoter region in gastric cancer and its related lesions. Mod Pathol 2006;19:675-83.
    • (2006) Mod Pathol , vol.19 , pp. 675-683
    • Wang, L.H.1    Choi, Y.L.2    Hua, X.Y.3
  • 30
    • 0031695171 scopus 로고    scopus 로고
    • A simple, precise and economical microdissection technique for analysis of genomic DNA from archival tissue sections
    • Lee JY, Dong SM, Kim SY, Yoo NJ, Lee SH, Park WS. A simple, precise and economical microdissection technique for analysis of genomic DNA from archival tissue sections. Virchows Arch 1998;433:305-9.
    • (1998) Virchows Arch , vol.433 , pp. 305-309
    • Lee, J.Y.1    Dong, S.M.2    Kim, S.Y.3    Yoo, N.J.4    Lee, S.H.5    Park, W.S.6
  • 31
    • 0034006788 scopus 로고    scopus 로고
    • Identification of methylated cytosine from archival formalin-fixed paraffin-embedded specimens
    • Kitazawa S, Kitazawa R, Maeda S. Identification of methylated cytosine from archival formalin-fixed paraffin-embedded specimens. Lab Invest 2000;80:275-6.
    • (2000) Lab Invest , vol.80 , pp. 275-276
    • Kitazawa, S.1    Kitazawa, R.2    Maeda, S.3
  • 32
    • 1142311552 scopus 로고    scopus 로고
    • Expression of BRCA1 protein in benign, borderline, and malignant epithelial ovarian neoplasms and its relationship to methylation and allelic loss of the BRCA1 gene
    • Wang C, Horiuchi A, Imai T, et al. Expression of BRCA1 protein in benign, borderline, and malignant epithelial ovarian neoplasms and its relationship to methylation and allelic loss of the BRCA1 gene. J Pathol 2004;202:215-23.
    • (2004) J Pathol , vol.202 , pp. 215-223
    • Wang, C.1    Horiuchi, A.2    Imai, T.3
  • 33
    • 7844251203 scopus 로고    scopus 로고
    • Mutations in DPC4 (SMAD4) cause juvenile polyposis syndrome, but only account for a minority of cases
    • Houlston R, Bevan S, Williams A, et al. Mutations in DPC4 (SMAD4) cause juvenile polyposis syndrome, but only account for a minority of cases. Hum Mol Genet 1998;7:1907-12.
    • (1998) Hum Mol Genet , vol.7 , pp. 1907-1912
    • Houlston, R.1    Bevan, S.2    Williams, A.3
  • 34
    • 0035882538 scopus 로고    scopus 로고
    • Inhibition of proteasome function induced apoptosis in gastric cancer
    • Fan XM, Wong BC, Wang WP, et al. Inhibition of proteasome function induced apoptosis in gastric cancer, Int J Cancer 2001;93:481-8.
    • (2001) Int J Cancer , vol.93 , pp. 481-488
    • Fan, X.M.1    Wong, B.C.2    Wang, W.P.3
  • 35
    • 0037969195 scopus 로고    scopus 로고
    • Aberrant signaling of TGF-β1 by the mutant Smad4 in gastric cancer cells
    • Ju HR, Jung U, Sonn CH, et al. Aberrant signaling of TGF-β1 by the mutant Smad4 in gastric cancer cells. Cancer Lett 2003;196:197-206.
    • (2003) Cancer Lett , vol.196 , pp. 197-206
    • Ju, H.R.1    Jung, U.2    Sonn, C.H.3
  • 36
    • 13844320649 scopus 로고    scopus 로고
    • Aberrant DNA methylation as a cancer-inducing mechanism
    • Esteller M. Aberrant DNA methylation as a cancer-inducing mechanism. Annu Rev Pharmacol Toxicol 2005;45:629-56.
    • (2005) Annu Rev Pharmacol Toxicol , vol.45 , pp. 629-656
    • Esteller, M.1
  • 38
    • 0036792534 scopus 로고    scopus 로고
    • Different pattern of allelic loss in Epstein-Barr virus-positive gastric cancer with emphasis on the p53 tumor suppressor pathway
    • van Rees BP, Caspers E, zur Hausen A, et al. Different pattern of allelic loss in Epstein-Barr virus-positive gastric cancer with emphasis on the p53 tumor suppressor pathway. Am J Pathol 2002;161:1207-13.
    • (2002) Am J Pathol , vol.161 , pp. 1207-1213
    • van Rees, B.P.1    Caspers, E.2    zur Hausen, A.3
  • 39
    • 7144256245 scopus 로고    scopus 로고
    • Monoallelic expression of the interleukin-2 locus
    • Hollander GA, Zuklys S, Morel C, et al. Monoallelic expression of the interleukin-2 locus. Science 1998; 279:2118-21.
    • (1998) Science , vol.279 , pp. 2118-2121
    • Hollander, G.A.1    Zuklys, S.2    Morel, C.3
  • 40
    • 0037422181 scopus 로고    scopus 로고
    • TGF-β-induced nuclear localization of Smad2 and Smad3 in Smad4 null cancer cell lines
    • Fink SP, Mikkola D, Willson JK, Markowitz S. TGF-β-induced nuclear localization of Smad2 and Smad3 in Smad4 null cancer cell lines. Oncogene 2003;22:1317-23.
    • (2003) Oncogene , vol.22 , pp. 1317-1323
    • Fink, S.P.1    Mikkola, D.2    Willson, J.K.3    Markowitz, S.4
  • 41
    • 11144358223 scopus 로고    scopus 로고
    • Loss of Smad4 correlates with loss of the invasion suppressor E-cadherin in advanced colorectal carcinomas
    • Reinacher-Schick A, Baldus SE, Romdhana B, et al. Loss of Smad4 correlates with loss of the invasion suppressor E-cadherin in advanced colorectal carcinomas. J Pathol 2004;202:412-20.
    • (2004) J Pathol , vol.202 , pp. 412-420
    • Reinacher-Schick, A.1    Baldus, S.E.2    Romdhana, B.3
  • 42
    • 0037026605 scopus 로고    scopus 로고
    • Smad4 induces the tumor suppressor E-cadherin and P-cadherin in colon carcinoma cells
    • Muller N, Reinacher-Schick A, Baldus SE, et al. Smad4 induces the tumor suppressor E-cadherin and P-cadherin in colon carcinoma cells. Oncogene 2002; 21:6049-58.
    • (2002) Oncogene , vol.21 , pp. 6049-6058
    • Muller, N.1    Reinacher-Schick, A.2    Baldus, S.E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.