Whole-genome sequencing and comprehensive molecular profiling identify new driver mutations in gastric cancer

Nature Genetics

Volumn 46, Issue 6, 2014, Pages 573-582

  Wang, Kai ^a   Yuen, Siu Tsan ^b   Xu, Jiangchun ^a,e   Lee, Siu Po ^b   Yan, Helen H N ^b   Shi, Stephanie T ^a   Siu, Hoi Cheong ^b   Deng, Shibing ^a   Chu, Kent Man ^b   Law, Simon ^b   Chan, Kok Hoe ^b   Chan, Annie S Y ^b   Tsui, Wai Yin ^b   Ho, Siu Lun ^b   Chan, Anthony K W ^b   Man, Jonathan L K ^b   Foglizzo, Valentina ^c   Ng, Man Kin ^b   Chan, April S ^b   Ching, Yick Pang ^b   Cheng, Grace H W ^b   Xie, Tao ^a   Fernandez, Julio ^a   Li, Vivian S W ^c   Clevers, Hans ^d   Rejto, Paul A ^a   Mao, Mao ^a,f   Leung, Suet Yi ^b   more..

^a PFIZER INC   (United States)

^b UNIVERSITY OF HONG KONG   (Hong Kong)

^c NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

^d UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^e Quanticel Pharmaceuticals Inc   (United States)

^f WUXI APPTEC   (China)

Author keywords

[No Author keywords available]

Indexed keywords

MUCIN 6; PROTEIN P53; RETINOBLASTOMA BINDING PROTEIN 2; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; TRANSCRIPTION FACTOR GLI3; UVOMORULIN;

ANOIKIS; ARID1A GENE; ARTICLE; CDH1 GENE; CELL JUNCTION; CHROMOSOME INVERSION; CHROMOSOME TRANSLOCATION; CONTROLLED STUDY; COPY NUMBER VARIATION; CTNNA2 GENE; DEMETHYLATION; DNA METHYLATION; EPIGENETICS; FEMALE; FOCAL ADHESION; GENE DOSAGE; GENE EXPRESSION PROFILING; GENE SEQUENCE; GENETIC ASSOCIATION; GENOME ANALYSIS; GLI3 GENE; HUMAN; HUMAN CELL; HUMAN TISSUE; INDEL MUTATION; MAJOR CLINICAL STUDY; MALE; MICROSATELLITE INSTABILITY; MUC6 GENE; ONCOGENE; PERSONALIZED MEDICINE; PRIORITY JOURNAL; RHOA GENE; RNF43 GENE; SINGLE NUCLEOTIDE POLYMORPHISM; SOMATIC MUTATION; STOMACH CANCER; STOMACH CARCINOGENESIS; TP53 GENE; TUMOR ESCAPE; TUMOR SUPPRESSOR GENE;

ADHERENS JUNCTIONS; ALGORITHMS; ANIMALS; DNA METHYLATION; DNA MUTATIONAL ANALYSIS; EPIGENESIS, GENETIC; FEMALE; GENE DOSAGE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; GENETIC VARIATION; GENOME, HUMAN; HEK293 CELLS; HUMANS; MALE; MICE; MICE, INBRED C57BL; MUTATION; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; RHOA GTP-BINDING PROTEIN; STOMACH NEOPLASMS;

EID: 84901680089     PISSN: 10614036     EISSN: 15461718     Source Type: Journal    
DOI: 10.1038/ng.2983     Document Type: Article

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