Acyclic Cucurbit[n]uril-Type Molecular Containers: Influence of Linker Length on Their Function as Solubilizing Agents

ChemMedChem

Volumn 11, Issue 9, 2016, Pages 980-989

  Sigwalt, David ^a   Moncelet, Damien ^a   Falcinelli, Shane ^a   Mandadapu, Vijaybabu ^b   Zavalij, Peter Y ^a   Day, Anthony ^b   Briken, Volker ^a   Isaacs, Lyle ^a  

^a Bldg 142   (United States)

^b UNIVERSITY OF NEW SOUTH WALES   (Australia)

Author keywords

cucurbiturils; cyclodextrins; host guest chemistry; molecular recognition; solubilizing excipients

Indexed keywords

2 HYDROXYPROPYL BETA CYCLODEXTRIN; BETA CYCLODEXTRIN SULFOBUTYL ETHER; SOLUBILIZER; WATER; 2-HYDROXYPROPYL-BETA-CYCLODEXTRIN; BETA CYCLODEXTRIN DERIVATIVE; BRIDGED COMPOUND; CUCURBIT(2)URIL; CUCURBIT(4)URIL; IMIDAZOLE DERIVATIVE;

ARTICLE; CYTOTOXICITY; DILUTION; IN VITRO STUDY; IN VIVO STUDY; MAXIMUM TOLERATED DOSE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; SOLUBILITY; ANIMAL; BODY WEIGHT; CELL SURVIVAL; CHEMISTRY; CONFORMATION; DRUG DESIGN; DRUG EFFECTS; FEMALE; HEK293 CELL LINE; HEP-G2 CELL LINE; HUMAN; KINETICS; TUMOR CELL LINE; X RAY CRYSTALLOGRAPHY;

ANIMALS; BETA-CYCLODEXTRINS; BODY WEIGHT; BRIDGED-RING COMPOUNDS; CELL LINE, TUMOR; CELL SURVIVAL; CRYSTALLOGRAPHY, X-RAY; DRUG DESIGN; FEMALE; HEK293 CELLS; HEP G2 CELLS; HUMANS; IMIDAZOLES; KINETICS; MICE; MOLECULAR CONFORMATION; SOLUBILITY;

EID: 84962491420     PISSN: 18607179     EISSN: 18607187     Source Type: Journal    
DOI: 10.1002/cmdc.201600090     Document Type: Article

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