Acyclic cucurbit[n]uril-type molecular containers: Influence of aromatic walls on their function as solubilizing excipients for insoluble drugs

Journal of Medicinal Chemistry

Volumn 57, Issue 22, 2014, Pages 9554-9563

  Zhang, Ben ^a   Isaacs, Lyle ^a  

^a Bldg 142   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACYCLIC CUCURBIT[N]URIL; ALBENDAZOLE; AMIODARONE; ANTINEOPLASTIC AGENT; BETA CYCLODEXTRIN DERIVATIVE; CAMPTOTHECIN; CINNARIZINE; DOCETAXEL; ESTRADIOL; ETHINYLESTRADIOL; EXCIPIENT; FENOFIBRATE; FULVESTRANT; INDOMETACIN; ITRACONAZOLE; MELPHALAN; PACLITAXEL; PBS 1086; SOLUBILIZER; TAMOXIFEN; TOLFENAMIC ACID; UNCLASSIFIED DRUG; VORICONAZOLE; ZIPRASIDONE; AMMONIUM DERIVATIVE; CATION; CUCURBITURIL; CYCLODEXTRIN; MACROCYCLIC COMPOUND; PROTEIN BINDING; STEROID;

AROMATIZATION; ARTICLE; BINDING AFFINITY; CHEMICAL STRUCTURE; COMPLEX FORMATION; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG SOLUBILITY; SOLUBILITY; SYNTHESIS; CHEMISTRY; DRUG DESIGN; KINETICS; MEDICINAL CHEMISTRY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROCEDURES; X RAY CRYSTALLOGRAPHY;

AMMONIUM COMPOUNDS; ANTINEOPLASTIC AGENTS; CATIONS; CHEMISTRY, PHARMACEUTICAL; CRYSTALLOGRAPHY, X-RAY; CYCLODEXTRINS; DRUG DESIGN; EXCIPIENTS; KINETICS; MACROCYCLIC COMPOUNDS; MAGNETIC RESONANCE SPECTROSCOPY; PROTEIN BINDING; SOLUBILITY; STEROIDS;

EID: 84913570535     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm501276u     Document Type: Article

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