The role of RNA editing by ADAR1 in prevention of innate immune sensing of self-RNA

Journal of Molecular Medicine

Volumn 94, Issue 10, 2016, Pages 1095-1102

  Heraud Farlow, Jacki E ^a   Walkley, Carl R ^a,b  

^a ST VINCENT'S INSTITUTE OF MEDICAL RESEARCH   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

ADAR1; dsRNA; Innate immune sensing; Interferonopathy; MDA5; RNA editing

Indexed keywords

ADAR1 PROTEIN; ADENOSINE; DOUBLE STRANDED RNA; INOSINE; INTERFERON; MAVS PROTEIN; MDA5 PROTEIN; RNA; RNA BINDING PROTEIN; UNCLASSIFIED DRUG; ADAR1 PROTEIN, HUMAN; ADENOSINE DEAMINASE; IFIH1 PROTEIN, HUMAN; INTERFERON INDUCED HELICASE C DOMAIN CONTAINING PROTEIN 1; SIGNAL TRANSDUCING ADAPTOR PROTEIN; VISA PROTEIN, HUMAN;

CYTOPLASM; CYTOSOL; GENETIC DISORDER; HUMAN; HUMAN GENETICS; INNATE IMMUNITY; NONHUMAN; REVIEW; RNA EDITING; RNA STRUCTURE; RNA VIRUS; SIGNAL TRANSDUCTION; TYPE 1 INTERFERONOPATHY; ANIMAL; IMMUNOLOGY;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADENOSINE DEAMINASE; ANIMALS; CYTOPLASM; HUMANS; IMMUNITY, INNATE; INTERFERON-INDUCED HELICASE, IFIH1; RNA; RNA EDITING; RNA-BINDING PROTEINS;

EID: 84962204142     PISSN: 09462716     EISSN: 14321440     Source Type: Journal    
DOI: 10.1007/s00109-016-1416-1     Document Type: Review

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