Editing of cellular self-RNAs by adenosine deaminase ADAR1 suppresses innate immune stress responses

Journal of Biological Chemistry

Volumn 291, Issue 12, 2016, Pages 6158-6168

  George, Cyril X ^a   Ramaswami, Gokul ^b   Li, Jin Billy ^b   Samuel, Charles E ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b STANFORD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BIOSYNTHESIS; CELL CULTURE; CELLS; CYTOLOGY; FIBROBLASTS; GRANULATION; IMMUNE SYSTEM; MAMMALS; PROTEINS; RNA;

ADENOSINE DEAMINASES; DOUBLE-STRANDED RNA; DUPLEX STRUCTURES; INITIATION FACTORS; INNATE IMMUNE RESPONSE; MOUSE EMBRYO FIBROBLASTS; PATHOGEN INFECTION; PROTEIN SYNTHESIS;

NUCLEIC ACIDS;

ADENOSINE DEAMINASE; ADENOSINE DEAMINASE ACTING ON DOUBLE STRANDED RNA 1; ADENOSINE DEAMINASE ACTING ON DOUBLE STRANDED RNA 2; INITIATION FACTOR 2ALPHA; INTERFERON; PROTEIN P15; UNCLASSIFIED DRUG; ADAR1 PROTEIN, MOUSE; ADAR2 PROTEIN, MOUSE; ALPHA INTERFERON; DOUBLE STRANDED RNA; INITIATION FACTOR 2; RNA BINDING PROTEIN;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; EMBRYO; ENZYME ACTIVITY; INNATE IMMUNITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN SECONDARY STRUCTURE; PROTEIN SYNTHESIS; RNA EDITING; ANIMAL; CELL CULTURE; CELL GRANULE; DEAMINATION; FIBROBLAST; GENETICS; IMMUNOLOGICAL TOLERANCE; KNOCKOUT MOUSE; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY; PROTEIN PROCESSING; SIGNAL TRANSDUCTION;

ADENOSINE DEAMINASE; ANIMALS; CELLS, CULTURED; CYTOPLASMIC GRANULES; DEAMINATION; EUKARYOTIC INITIATION FACTOR-2; FIBROBLASTS; IMMUNE TOLERANCE; IMMUNITY, INNATE; INTERFERON-ALPHA; MICE, KNOCKOUT; PHOSPHORYLATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; RNA EDITING; RNA, DOUBLE-STRANDED; RNA-BINDING PROTEINS; SIGNAL TRANSDUCTION;

EID: 84964780455     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M115.709014     Document Type: Article

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