-
1
-
-
69949159308
-
Nicotinic receptors: allosteric transitions and therapeutic targets in the nervous system
-
19721446, .;():–.
-
Taly A, Corringer PJ, Guedin D, Lestage P, Changeux JP, Nicotinic receptors: allosteric transitions and therapeutic targets in the nervous system. Nat Rev Drug Discov. 2009;8(9):733–50. 19721446. doi: 10.1038/nrd2927
-
(2009)
Nat Rev Drug Discov
, vol.8
, Issue.9
, pp. 733-750
-
-
Taly, A.1
Corringer, P.J.2
Guedin, D.3
Lestage, P.4
Changeux, J.P.5
-
2
-
-
33645302360
-
Recent advances in Cys-loop receptor structure and function
-
16554804, .;():–.
-
Sine SM, Engel AG, Recent advances in Cys-loop receptor structure and function. Nature. 2006;440(7083):448–55. 16554804.
-
(2006)
Nature
, vol.440
, Issue.7083
, pp. 448-455
-
-
Sine, S.M.1
Engel, A.G.2
-
3
-
-
0014115893
-
On the application of "a plausible model" of allosteric proteins to the receptor for acetylcholine
-
6048545, .;():–.
-
Karlin A, On the application of "a plausible model" of allosteric proteins to the receptor for acetylcholine. J Theor Biol. 1967;16(2):306–20. 6048545.
-
(1967)
J Theor Biol
, vol.16
, Issue.2
, pp. 306-320
-
-
Karlin, A.1
-
4
-
-
0031745831
-
Allosteric transitions of the acetylcholine receptor
-
9615170, .;:–.
-
Edelstein SJ, Changeux JP, Allosteric transitions of the acetylcholine receptor. Adv Protein Chem. 1998;51:121–84. 9615170.
-
(1998)
Adv Protein Chem
, vol.51
, pp. 121-184
-
-
Edelstein, S.J.1
Changeux, J.P.2
-
5
-
-
84855175213
-
Thinking in cycles: MWC is a good model for acetylcholine receptor-channels
-
21807612, .;():–.
-
Auerbach A, Thinking in cycles: MWC is a good model for acetylcholine receptor-channels. J Physiol. 2012;590(Pt 1):93–8. doi: 10.1113/jphysiol.2011.21468421807612.
-
(2012)
J Physiol
, vol.590
, pp. 93-98
-
-
Auerbach, A.1
-
6
-
-
26944443142
-
Identification of the prokaryotic ligand-gated ion channels and their implications for the mechanisms and origins of animal Cys-loop ion channels
-
15642096, .;():.
-
Tasneem A, Iyer LM, Jakobsson E, Aravind L, Identification of the prokaryotic ligand-gated ion channels and their implications for the mechanisms and origins of animal Cys-loop ion channels. Genome Biol. 2005;6(1):R4. 15642096.
-
(2005)
Genome Biol
, vol.6
, Issue.1
, pp. R4
-
-
Tasneem, A.1
Iyer, L.M.2
Jakobsson, E.3
Aravind, L.4
-
7
-
-
2542432136
-
Cys-loop receptors: new twists and turns
-
15165737, .;():–.
-
Lester HA, Dibas MI, Dahan DS, Leite JF, Dougherty DA, Cys-loop receptors: new twists and turns. Trends Neurosci. 2004;27(6):329–36. 15165737.
-
(2004)
Trends Neurosci
, vol.27
, Issue.6
, pp. 329-336
-
-
Lester, H.A.1
Dibas, M.I.2
Dahan, D.S.3
Leite, J.F.4
Dougherty, D.A.5
-
8
-
-
33846106078
-
A prokaryotic proton-gated ion channel from the nicotinic acetylcholine receptor family
-
17167423, ..;():–.
-
Bocquet N, Prado de Carvalho L, Cartaud J, Neyton J, Le Poupon C, Taly A, et al. A prokaryotic proton-gated ion channel from the nicotinic acetylcholine receptor family. Nature. 2007;445(7123):116–9. 17167423.
-
(2007)
Nature
, vol.445
, Issue.7123
, pp. 116-119
-
-
Bocquet, N.1
Prado de Carvalho, L.2
Cartaud, J.3
Neyton, J.4
Le Poupon, C.5
Taly, A.6
-
9
-
-
79959775185
-
Ligand activation of the prokaryotic pentameric ligand-gated ion channel ELIC
-
21713033, .;():. Epub 2011/06/30.
-
Zimmermann I, Dutzler R, Ligand activation of the prokaryotic pentameric ligand-gated ion channel ELIC. PLoS Biol. 2011;9(6):e1001101. Epub 2011/06/30. doi: 10.1371/journal.pbio.100110121713033.
-
(2011)
PLoS Biol
, vol.9
, Issue.6
, pp. e1001101
-
-
Zimmermann, I.1
Dutzler, R.2
-
10
-
-
13444271681
-
Refined structure of the nicotinic acetylcholine receptor at 4A resolution
-
15701510, .;():–.
-
Unwin N, Refined structure of the nicotinic acetylcholine receptor at 4A resolution. J Mol Biol. 2005;346(4):967–89. 15701510.
-
(2005)
J Mol Biol
, vol.346
, Issue.4
, pp. 967-989
-
-
Unwin, N.1
-
11
-
-
0038112088
-
Structure and gating mechanism of the acetylcholine receptor pore
-
12827192, .;():–.
-
Miyazawa A, Fujiyoshi Y, Unwin N, Structure and gating mechanism of the acetylcholine receptor pore. Nature. 2003;423(6943):949–55. 12827192.
-
(2003)
Nature
, vol.423
, Issue.6943
, pp. 949-955
-
-
Miyazawa, A.1
Fujiyoshi, Y.2
Unwin, N.3
-
12
-
-
84944273234
-
Glycine receptor mechanism elucidated by electron cryo-microscopy
-
26344198, .;():–.
-
Du J, Lu W, Wu S, Cheng Y, Gouaux E, Glycine receptor mechanism elucidated by electron cryo-microscopy. Nature. 2015;526(7572):224–9. doi: 10.1038/nature1485326344198.
-
(2015)
Nature
, vol.526
, Issue.7572
, pp. 224-229
-
-
Du, J.1
Lu, W.2
Wu, S.3
Cheng, Y.4
Gouaux, E.5
-
13
-
-
41149168686
-
X-ray structure of a prokaryotic pentameric ligand-gated ion channel
-
18322461, .;():–.
-
Hilf RJ, Dutzler R, X-ray structure of a prokaryotic pentameric ligand-gated ion channel. Nature. 2008;452(7185):375–9. 18322461. doi: 10.1038/nature06717
-
(2008)
Nature
, vol.452
, Issue.7185
, pp. 375-379
-
-
Hilf, R.J.1
Dutzler, R.2
-
14
-
-
58149242730
-
Structure of a potentially open state of a proton-activated pentameric ligand-gated ion channel
-
18987630, .;():–.
-
Hilf RJ, Dutzler R, Structure of a potentially open state of a proton-activated pentameric ligand-gated ion channel. Nature. 2009;457(7225):115–8. 18987630. doi: 10.1038/nature07461
-
(2009)
Nature
, vol.457
, Issue.7225
, pp. 115-118
-
-
Hilf, R.J.1
Dutzler, R.2
-
15
-
-
58149267953
-
X-ray structure of a pentameric ligand-gated ion channel in an apparently open conformation
-
18987633, ..;():–.
-
Bocquet N, Nury H, Baaden M, Le Poupon C, Changeux JP, Delarue M, et al. X-ray structure of a pentameric ligand-gated ion channel in an apparently open conformation. Nature. 2009;457(7225):111–4. 18987633. doi: 10.1038/nature07462
-
(2009)
Nature
, vol.457
, Issue.7225
, pp. 111-114
-
-
Bocquet, N.1
Nury, H.2
Baaden, M.3
Le Poupon, C.4
Changeux, J.P.5
Delarue, M.6
-
16
-
-
79957953215
-
Principles of activation and permeation in an anion-selective Cys-loop receptor
-
21572436, .;():–.
-
Hibbs RE, Gouaux E, Principles of activation and permeation in an anion-selective Cys-loop receptor. Nature. 2011;474(7349):54–60. 21572436. doi: 10.1038/nature10139
-
(2011)
Nature
, vol.474
, Issue.7349
, pp. 54-60
-
-
Hibbs, R.E.1
Gouaux, E.2
-
17
-
-
84905669878
-
Crystal structure of a human GABAA receptor
-
24909990, .;():–.
-
Miller PS, Aricescu AR, Crystal structure of a human GABAA receptor. Nature. 2014;512(7514):270–5. doi: 10.1038/nature1329324909990.
-
(2014)
Nature
, vol.512
, Issue.7514
, pp. 270-275
-
-
Miller, P.S.1
Aricescu, A.R.2
-
18
-
-
84906545550
-
X-ray structure of the mouse serotonin 5-HT3 receptor
-
25119048, ..;():–.
-
Hassaine G, Deluz C, Grasso L, Wyss R, Tol MB, Hovius R, et al. X-ray structure of the mouse serotonin 5-HT3 receptor. Nature. 2014;512(7514):276–81. doi: 10.1038/nature1355225119048.
-
(2014)
Nature
, vol.512
, Issue.7514
, pp. 276-281
-
-
Hassaine, G.1
Deluz, C.2
Grasso, L.3
Wyss, R.4
Tol, M.B.5
Hovius, R.6
-
19
-
-
84906568725
-
X-ray structures of GluCl in apo states reveal a gating mechanism of Cys-loop receptors
-
25143115, .;():–.
-
Althoff T, Hibbs RE, Banerjee S, Gouaux E, X-ray structures of GluCl in apo states reveal a gating mechanism of Cys-loop receptors. Nature. 2014;512(7514):333–7. doi: 10.1038/nature1366925143115.
-
(2014)
Nature
, vol.512
, Issue.7514
, pp. 333-337
-
-
Althoff, T.1
Hibbs, R.E.2
Banerjee, S.3
Gouaux, E.4
-
20
-
-
84892910277
-
Crystal structures of a pentameric ligand-gated ion channel provide a mechanism for activation
-
24367074, ..;():–.
-
Sauguet L, Shahsavar A, Poitevin F, Huon C, Menny A, Nemecz A, et al. Crystal structures of a pentameric ligand-gated ion channel provide a mechanism for activation. Proc Natl Acad Sci U S A. 2014;111(3):966–71. doi: 10.1073/pnas.131499711124367074.
-
(2014)
Proc Natl Acad Sci U S A
, vol.111
, Issue.3
, pp. 966-971
-
-
Sauguet, L.1
Shahsavar, A.2
Poitevin, F.3
Huon, C.4
Menny, A.5
Nemecz, A.6
-
21
-
-
84944052478
-
Crystal structure of human glycine receptor-alpha3 bound to antagonist strychnine
-
26416729, .;():–.
-
Huang X, Chen H, Michelsen K, Schneider S, Shaffer PL, Crystal structure of human glycine receptor-alpha3 bound to antagonist strychnine. Nature. 2015;526(7572):277–80. doi: 10.1038/nature1497226416729.
-
(2015)
Nature
, vol.526
, Issue.7572
, pp. 277-280
-
-
Huang, X.1
Chen, H.2
Michelsen, K.3
Schneider, S.4
Shaffer, P.L.5
-
22
-
-
84881437750
-
Gating of pentameric ligand-gated ion channels: structural insights and ambiguities
-
23931140, .;():–.
-
daCosta CJ, Baenziger JE, Gating of pentameric ligand-gated ion channels: structural insights and ambiguities. Structure. 2013;21(8):1271–83. doi: 10.1016/j.str.2013.06.01923931140.
-
(2013)
Structure
, vol.21
, Issue.8
, pp. 1271-1283
-
-
daCosta, C.J.1
Baenziger, J.E.2
-
23
-
-
73649096172
-
Crystal Structure of the Extracellular Domain of a Bacterial Ligand-Gated Ion Channel
-
19917292, ...
-
Nury H, Bocquet N, Le Poupon C, Raynal B, Haouz A, Corringer PJ, et al. Crystal Structure of the Extracellular Domain of a Bacterial Ligand-Gated Ion Channel. J Mol Biol. 2009. 19917292.
-
(2009)
J Mol Biol
-
-
Nury, H.1
Bocquet, N.2
Le Poupon, C.3
Raynal, B.4
Haouz, A.5
Corringer, P.J.6
-
24
-
-
34547520128
-
Crystal structure of the extracellular domain of nAChR alpha1 bound to alpha-bungarotoxin at 1.94 A resolution
-
17643119, .;():–.
-
Dellisanti CD, Yao Y, Stroud JC, Wang ZZ, Chen L, Crystal structure of the extracellular domain of nAChR alpha1 bound to alpha-bungarotoxin at 1.94 A resolution. Nat Neurosci. 2007;10(8):953–62. 17643119.
-
(2007)
Nat Neurosci
, vol.10
, Issue.8
, pp. 953-962
-
-
Dellisanti, C.D.1
Yao, Y.2
Stroud, J.C.3
Wang, Z.Z.4
Chen, L.5
-
25
-
-
77953709862
-
NMR structure of the transmembrane domain of the n-acetylcholine receptor beta2 subunit
-
20441771, .;():–.
-
Bondarenko V, Tillman T, Xu Y, Tang P, NMR structure of the transmembrane domain of the n-acetylcholine receptor beta2 subunit. Biochim Biophys Acta. 2010;1798(8):1608–14. doi: 10.1016/j.bbamem.2010.04.01420441771.
-
(2010)
Biochim Biophys Acta
, vol.1798
, Issue.8
, pp. 1608-1614
-
-
Bondarenko, V.1
Tillman, T.2
Xu, Y.3
Tang, P.4
-
26
-
-
0041352143
-
Acetylcholine binding protein (AChBP): a secreted glial protein that provides a high-resolution model for the extracellular domain of pentameric ligand-gated ion channels
-
12695308, .;:–.
-
Sixma TK, Smit AB, Acetylcholine binding protein (AChBP): a secreted glial protein that provides a high-resolution model for the extracellular domain of pentameric ligand-gated ion channels. Annu Rev Biophys Biomol Struct. 2003;32:311–34. 12695308.
-
(2003)
Annu Rev Biophys Biomol Struct
, vol.32
, pp. 311-334
-
-
Sixma, T.K.1
Smit, A.B.2
-
27
-
-
4344616080
-
Coupling of agonist binding to channel gating in an ACh-binding protein linked to an ion channel
-
15318223, ..;():–.
-
Bouzat C, Gumilar F, Spitzmaul G, Wang HL, Rayes D, Hansen SB, et al. Coupling of agonist binding to channel gating in an ACh-binding protein linked to an ion channel. Nature. 2004;430(7002):896–900. 15318223.
-
(2004)
Nature
, vol.430
, Issue.7002
, pp. 896-900
-
-
Bouzat, C.1
Gumilar, F.2
Spitzmaul, G.3
Wang, H.L.4
Rayes, D.5
Hansen, S.B.6
-
28
-
-
69249088472
-
A prokaryotic perspective on pentameric ligand-gated ion channel structure
-
19646860, .;():–.
-
Hilf RJ, Dutzler R, A prokaryotic perspective on pentameric ligand-gated ion channel structure. Curr Opin Struct Biol. 2009;19(4):418–24. 19646860. doi: 10.1016/j.sbi.2009.07.006
-
(2009)
Curr Opin Struct Biol
, vol.19
, Issue.4
, pp. 418-424
-
-
Hilf, R.J.1
Dutzler, R.2
-
29
-
-
84920385268
-
Mechanism of activation of the prokaryotic channel ELIC by propylamine: a single-channel study
-
25548135, .;():–.
-
Marabelli A, Lape R, Sivilotti L, Mechanism of activation of the prokaryotic channel ELIC by propylamine: a single-channel study. J Gen Physiol. 2015;145(1):23–45. doi: 10.1085/jgp.20141123425548135.
-
(2015)
J Gen Physiol
, vol.145
, Issue.1
, pp. 23-45
-
-
Marabelli, A.1
Lape, R.2
Sivilotti, L.3
-
30
-
-
84870266525
-
Inhibition of the prokaryotic pentameric ligand-gated ion channel ELIC by divalent cations
-
23185134, .;():.
-
Zimmermann I, Marabelli A, Bertozzi C, Sivilotti LG, Dutzler R, Inhibition of the prokaryotic pentameric ligand-gated ion channel ELIC by divalent cations. PLoS Biol. 2012;10(11):e1001429. doi: 10.1371/journal.pbio.100142923185134.
-
(2012)
PLoS Biol
, vol.10
, Issue.11
, pp. e1001429
-
-
Zimmermann, I.1
Marabelli, A.2
Bertozzi, C.3
Sivilotti, L.G.4
Dutzler, R.5
-
31
-
-
78549271990
-
Structural basis of open channel block in a prokaryotic pentameric ligand-gated ion channel
-
21037567, .;():–.
-
Hilf RJ, Bertozzi C, Zimmermann I, Reiter A, Trauner D, Dutzler R, Structural basis of open channel block in a prokaryotic pentameric ligand-gated ion channel. Nat Struct Mol Biol. 2010;17(11):1330–6. 21037567. doi: 10.1038/nsmb.1933
-
(2010)
Nat Struct Mol Biol
, vol.17
, Issue.11
, pp. 1330-1336
-
-
Hilf, R.J.1
Bertozzi, C.2
Zimmermann, I.3
Reiter, A.4
Trauner, D.5
Dutzler, R.6
-
32
-
-
84859173541
-
Structure of the pentameric ligand-gated ion channel ELIC cocrystallized with its competitive antagonist acetylcholine
-
22395605, ..;:. Epub 2012/03/08.
-
Pan J, Chen Q, Willenbring D, Yoshida K, Tillman T, Kashlan OB, et al. Structure of the pentameric ligand-gated ion channel ELIC cocrystallized with its competitive antagonist acetylcholine. Nat Commun. 2012;3:714. Epub 2012/03/08. doi: 10.1038/ncomms170322395605.
-
(2012)
Nat Commun
, vol.3
, pp. 714
-
-
Pan, J.1
Chen, Q.2
Willenbring, D.3
Yoshida, K.4
Tillman, T.5
Kashlan, O.B.6
-
33
-
-
84861856196
-
A locally closed conformation of a bacterial pentameric proton-gated ion channel
-
22580559, ..;():–.
-
Prevost MS, Sauguet L, Nury H, Van Renterghem C, Huon C, Poitevin F, et al. A locally closed conformation of a bacterial pentameric proton-gated ion channel. Nat Struct Mol Biol. 2012;19(6):642–9. doi: 10.1038/nsmb.230722580559.
-
(2012)
Nat Struct Mol Biol
, vol.19
, Issue.6
, pp. 642-649
-
-
Prevost, M.S.1
Sauguet, L.2
Nury, H.3
Van Renterghem, C.4
Huon, C.5
Poitevin, F.6
-
34
-
-
84887444038
-
Gating of the proton-gated ion channel from Gloeobacter violaceus at pH 4 as revealed by X-ray crystallography
-
24167270, .;():–.
-
Gonzalez-Gutierrez G, Cuello LG, Nair SK, Grosman C, Gating of the proton-gated ion channel from Gloeobacter violaceus at pH 4 as revealed by X-ray crystallography. Proc Natl Acad Sci U S A. 2013;110(46):18716–21. doi: 10.1073/pnas.131315611024167270.
-
(2013)
Proc Natl Acad Sci U S A
, vol.110
, Issue.46
, pp. 18716-18721
-
-
Gonzalez-Gutierrez, G.1
Cuello, L.G.2
Nair, S.K.3
Grosman, C.4
-
35
-
-
84863116433
-
Intramembrane proton binding site linked to activation of bacterial pentameric ion channel
-
22084238, .;():–.
-
Wang HL, Cheng X, Sine SM, Intramembrane proton binding site linked to activation of bacterial pentameric ion channel. J Biol Chem. 2012;287(9):6482–9. doi: 10.1074/jbc.M111.30583922084238.
-
(2012)
J Biol Chem
, vol.287
, Issue.9
, pp. 6482-6489
-
-
Wang, H.L.1
Cheng, X.2
Sine, S.M.3
-
36
-
-
84919924163
-
Structural requirements in the transmembrane domain of GLIC revealed by incorporation of noncanonical histidine analogs
-
25525989, .;():–.
-
Rienzo M, Lummis SC, Dougherty DA, Structural requirements in the transmembrane domain of GLIC revealed by incorporation of noncanonical histidine analogs. Chem Biol. 2014;21(12):1700–6. doi: 10.1016/j.chembiol.2014.10.01925525989.
-
(2014)
Chem Biol
, vol.21
, Issue.12
, pp. 1700-1706
-
-
Rienzo, M.1
Lummis, S.C.2
Dougherty, D.A.3
-
37
-
-
84859963646
-
Mutations that stabilize the open state of the Erwinia chrisanthemi ligand-gated ion channel fail to change the conformation of the pore domain in crystals
-
22474383, .. Epub 2012/04/05.
-
Gonzalez-Gutierrez G, Lukk T, Agarwal V, Papke D, Nair SK, Grosman C, Mutations that stabilize the open state of the Erwinia chrisanthemi ligand-gated ion channel fail to change the conformation of the pore domain in crystals. Proc Natl Acad Sci U S A. 2012. Epub 2012/04/05. doi: 10.1073/pnas.111926810922474383.
-
(2012)
Proc Natl Acad Sci U S A
-
-
Gonzalez-Gutierrez, G.1
Lukk, T.2
Agarwal, V.3
Papke, D.4
Nair, S.K.5
Grosman, C.6
-
38
-
-
84889038866
-
Site-directed spin labeling reveals pentameric ligand-gated ion channel gating motions
-
24260024, ..;():.
-
Dellisanti CD, Ghosh B, Hanson SM, Raspanti JM, Grant VA, Diarra GM, et al. Site-directed spin labeling reveals pentameric ligand-gated ion channel gating motions. PLoS Biol. 2013;11(11):e1001714. doi: 10.1371/journal.pbio.100171424260024.
-
(2013)
PLoS Biol
, vol.11
, Issue.11
, pp. e1001714
-
-
Dellisanti, C.D.1
Ghosh, B.2
Hanson, S.M.3
Raspanti, J.M.4
Grant, V.A.5
Diarra, G.M.6
-
39
-
-
84890958919
-
-
24352193, .;:.
-
Purohit P, Gupta S, Jadey S, Auerbach A, Nat Commun. 2013;4:2984. doi: 10.1038/ncomms398424352193.
-
(2013)
Nat Commun
, vol.4
, pp. 2984
-
-
Purohit, P.1
Gupta, S.2
Jadey, S.3
Auerbach, A.4
-
40
-
-
70849100535
-
Structural basis of activation of cys-loop receptors: the extracellular-transmembrane interface as a coupling region
-
19859835, .;():–.
-
Bartos M, Corradi J, Bouzat C, Structural basis of activation of cys-loop receptors: the extracellular-transmembrane interface as a coupling region. Mol Neurobiol. 2009;40(3):236–52. doi: 10.1007/s12035-009-8084-x19859835.
-
(2009)
Mol Neurobiol
, vol.40
, Issue.3
, pp. 236-252
-
-
Bartos, M.1
Corradi, J.2
Bouzat, C.3
-
41
-
-
0037448581
-
Coupling of agonist binding to channel gating in the GABA(A) receptor
-
12529644, .;():–.
-
Kash TL, Jenkins A, Kelley JC, Trudell JR, Harrison NL, Coupling of agonist binding to channel gating in the GABA(A) receptor. Nature. 2003;421(6920):272–5. 12529644.
-
(2003)
Nature
, vol.421
, Issue.6920
, pp. 272-275
-
-
Kash, T.L.1
Jenkins, A.2
Kelley, J.C.3
Trudell, J.R.4
Harrison, N.L.5
-
42
-
-
0037329589
-
Mutation causing severe myasthenia reveals functional asymmetry of AChR signature cystine loops in agonist binding and gating
-
12588888, ..;():–.
-
Shen XM, Ohno K, Tsujino A, Brengman JM, Gingold M, Sine SM, et al. Mutation causing severe myasthenia reveals functional asymmetry of AChR signature cystine loops in agonist binding and gating. J Clin Invest. 2003;111(4):497–505. 12588888.
-
(2003)
J Clin Invest
, vol.111
, Issue.4
, pp. 497-505
-
-
Shen, X.M.1
Ohno, K.2
Tsujino, A.3
Brengman, J.M.4
Gingold, M.5
Sine, S.M.6
-
43
-
-
1842686239
-
Gating dynamics of the acetylcholine receptor extracellular domain
-
15051806, .;():–.
-
Chakrapani S, Bailey TD, Auerbach A, Gating dynamics of the acetylcholine receptor extracellular domain. J Gen Physiol. 2004;123(4):341–56. doi: 10.1085/jgp.20030900415051806.
-
(2004)
J Gen Physiol
, vol.123
, Issue.4
, pp. 341-356
-
-
Chakrapani, S.1
Bailey, T.D.2
Auerbach, A.3
-
44
-
-
0029954238
-
A single residue in the M2-M3 loop is a major determinant of coupling between binding and gating in neuronal nicotinic receptors
-
8650229, .;():–.
-
Campos-Caro A, Sala S, Ballesta JJ, Vicente-Agullo F, Criado M, Sala F, A single residue in the M2-M3 loop is a major determinant of coupling between binding and gating in neuronal nicotinic receptors. Proc Natl Acad Sci U S A. 1996;93(12):6118–23. 8650229.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, Issue.12
, pp. 6118-6123
-
-
Campos-Caro, A.1
Sala, S.2
Ballesta, J.J.3
Vicente-Agullo, F.4
Criado, M.5
Sala, F.6
-
45
-
-
0031027684
-
Identification of intracellular and extracellular domains mediating signal transduction in the inhibitory glycine receptor chloride channel
-
9009272, .;():–.
-
Lynch JW, Rajendra S, Pierce KD, Handford CA, Barry PH, Schofield PR, Identification of intracellular and extracellular domains mediating signal transduction in the inhibitory glycine receptor chloride channel. EMBO J. 1997;16(1):110–20. doi: 10.1093/emboj/16.1.1109009272.
-
(1997)
EMBO J
, vol.16
, Issue.1
, pp. 110-120
-
-
Lynch, J.W.1
Rajendra, S.2
Pierce, K.D.3
Handford, C.A.4
Barry, P.H.5
Schofield, P.R.6
-
46
-
-
0033811476
-
The extracellular linker of muscle acetylcholine receptor channels is a gating control element
-
10962011, .;():–.
-
Grosman C, Salamone FN, Sine SM, Auerbach A, The extracellular linker of muscle acetylcholine receptor channels is a gating control element. J Gen Physiol. 2000;116(3):327–40. 10962011.
-
(2000)
J Gen Physiol
, vol.116
, Issue.3
, pp. 327-340
-
-
Grosman, C.1
Salamone, F.N.2
Sine, S.M.3
Auerbach, A.4
-
47
-
-
36549043834
-
Acetylcholine receptor gating at extracellular transmembrane domain interface: the cys-loop and M2-M3 linker
-
18040057, .;():–.
-
Jha A, Cadugan DJ, Purohit P, Auerbach A, Acetylcholine receptor gating at extracellular transmembrane domain interface: the cys-loop and M2-M3 linker. J Gen Physiol. 2007;130(6):547–58. 18040057.
-
(2007)
J Gen Physiol
, vol.130
, Issue.6
, pp. 547-558
-
-
Jha, A.1
Cadugan, D.J.2
Purohit, P.3
Auerbach, A.4
-
48
-
-
49649099967
-
Gating at the mouth of the acetylcholine receptor channel: energetic consequences of mutations in the alphaM2-cap
-
18575616, .;():.
-
Bafna PA, Purohit PG, Auerbach A, Gating at the mouth of the acetylcholine receptor channel: energetic consequences of mutations in the alphaM2-cap. PLoS One. 2008;3(6):e2515. doi: 10.1371/journal.pone.000251518575616.
-
(2008)
PLoS One
, vol.3
, Issue.6
, pp. e2515
-
-
Bafna, P.A.1
Purohit, P.G.2
Auerbach, A.3
-
49
-
-
84894149129
-
Macroscopic kinetics of pentameric ligand gated ion channels: comparisons between two prokaryotic channels and one eukaryotic channel
-
24260369, .;():.
-
Laha KT, Ghosh B, Czajkowski C, Macroscopic kinetics of pentameric ligand gated ion channels: comparisons between two prokaryotic channels and one eukaryotic channel. PLoS ONE. 2013;8(11):e80322. doi: 10.1371/journal.pone.008032224260369.
-
(2013)
PLoS ONE
, vol.8
, Issue.11
, pp. e80322
-
-
Laha, K.T.1
Ghosh, B.2
Czajkowski, C.3
-
50
-
-
0032520102
-
Properties of human glycine receptors containing the hyperekplexia mutation alpha1(K276E), expressed in Xenopus oocytes
-
9490812, .;():–.
-
Lewis TM, Sivilotti LG, Colquhoun D, Gardiner RM, Schoepfer R, Rees M, Properties of human glycine receptors containing the hyperekplexia mutation alpha1(K276E), expressed in Xenopus oocytes. J Physiol. 1998;507 (Pt 1):25–40. 9490812.
-
(1998)
J Physiol
, vol.507
, pp. 25-40
-
-
Lewis, T.M.1
Sivilotti, L.G.2
Colquhoun, D.3
Gardiner, R.M.4
Schoepfer, R.5
Rees, M.6
-
51
-
-
50349093448
-
The interface between extracellular and transmembrane domains of homomeric Cys-loop receptors governs open-channel lifetime and rate of desensitization
-
18667613, .;():–.
-
Bouzat C, Bartos M, Corradi J, Sine SM, The interface between extracellular and transmembrane domains of homomeric Cys-loop receptors governs open-channel lifetime and rate of desensitization. J Neurosci. 2008;28(31):7808–19. doi: 10.1523/JNEUROSCI.0448-08.200818667613.
-
(2008)
J Neurosci
, vol.28
, Issue.31
, pp. 7808-7819
-
-
Bouzat, C.1
Bartos, M.2
Corradi, J.3
Sine, S.M.4
-
52
-
-
3543083927
-
Alanine-scanning mutagenesis in the signature disulfide loop of the glycine receptor alpha 1 subunit: critical residues for activation and modulation
-
15287733, .;():–.
-
Schofield CM, Trudell JR, Harrison NL, Alanine-scanning mutagenesis in the signature disulfide loop of the glycine receptor alpha 1 subunit: critical residues for activation and modulation. Biochemistry. 2004;43(31):10058–63. 15287733.
-
(2004)
Biochemistry
, vol.43
, Issue.31
, pp. 10058-10063
-
-
Schofield, C.M.1
Trudell, J.R.2
Harrison, N.L.3
-
53
-
-
29144514665
-
Molecular tuning of fast gating in pentameric ligand-gated ion channels
-
16319224, .;():–.
-
Grutter T, de Carvalho LP, Dufresne V, Taly A, Edelstein SJ, Changeux JP, Molecular tuning of fast gating in pentameric ligand-gated ion channels. Proc Natl Acad Sci U S A. 2005;102(50):18207–12. doi: 10.1073/pnas.050902410216319224.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, Issue.50
, pp. 18207-18212
-
-
Grutter, T.1
de Carvalho, L.P.2
Dufresne, V.3
Taly, A.4
Edelstein, S.J.5
Changeux, J.P.6
-
54
-
-
63849179080
-
Binding to gating transduction in nicotinic receptors: Cys-loop energetically couples to pre-M1 and M2-M3 regions
-
19279256, .;():–.
-
Lee WY, Free CR, Sine SM, Binding to gating transduction in nicotinic receptors: Cys-loop energetically couples to pre-M1 and M2-M3 regions. J Neurosci. 2009;29(10):3189–99. doi: 10.1523/JNEUROSCI.6185-08.200919279256.
-
(2009)
J Neurosci
, vol.29
, Issue.10
, pp. 3189-3199
-
-
Lee, W.Y.1
Free, C.R.2
Sine, S.M.3
-
55
-
-
29244442919
-
A unified view of the role of electrostatic interactions in modulating the gating of Cys loop receptors
-
16216879, .;():–.
-
Xiu X, Hanek AP, Wang J, Lester HA, Dougherty DA, A unified view of the role of electrostatic interactions in modulating the gating of Cys loop receptors. J Biol Chem. 2005;280(50):41655–66. doi: 10.1074/jbc.M50863520016216879.
-
(2005)
J Biol Chem
, vol.280
, Issue.50
, pp. 41655-41666
-
-
Xiu, X.1
Hanek, A.P.2
Wang, J.3
Lester, H.A.4
Dougherty, D.A.5
-
56
-
-
34548485996
-
Transducing agonist binding to channel gating involves different interactions in 5-HT3 and GABAC receptors
-
17606617, .;():–.
-
Price KL, Millen KS, Lummis SC, Transducing agonist binding to channel gating involves different interactions in 5-HT3 and GABAC receptors. J Biol Chem. 2007;282(35):25623–30. doi: 10.1074/jbc.M70252420017606617.
-
(2007)
J Biol Chem
, vol.282
, Issue.35
, pp. 25623-25630
-
-
Price, K.L.1
Millen, K.S.2
Lummis, S.C.3
-
57
-
-
0347379903
-
Role of charged residues in coupling ligand binding and channel activation in the extracellular domain of the glycine receptor
-
14525990, .;():–.
-
Absalom NL, Lewis TM, Kaplan W, Pierce KD, Schofield PR, Role of charged residues in coupling ligand binding and channel activation in the extracellular domain of the glycine receptor. J Biol Chem. 2003;278(50):50151–7. doi: 10.1074/jbc.M30535720014525990.
-
(2003)
J Biol Chem
, vol.278
, Issue.50
, pp. 50151-50157
-
-
Absalom, N.L.1
Lewis, T.M.2
Kaplan, W.3
Pierce, K.D.4
Schofield, P.R.5
-
58
-
-
36549039473
-
Acetylcholine receptor gating at extracellular transmembrane domain interface: the "pre-M1" linker
-
18040058, .;():–.
-
Purohit P, Auerbach A, Acetylcholine receptor gating at extracellular transmembrane domain interface: the "pre-M1" linker. J Gen Physiol. 2007;130(6):559–68. 18040058.
-
(2007)
J Gen Physiol
, vol.130
, Issue.6
, pp. 559-568
-
-
Purohit, P.1
Auerbach, A.2
-
59
-
-
27744438169
-
Principal pathway coupling agonist binding to channel gating in nicotinic receptors
-
16281039, .;():–.
-
Lee WY, Sine SM, Principal pathway coupling agonist binding to channel gating in nicotinic receptors. Nature. 2005;438(7065):243–7. 16281039.
-
(2005)
Nature
, vol.438
, Issue.7065
, pp. 243-247
-
-
Lee, W.Y.1
Sine, S.M.2
-
60
-
-
84893466183
-
Structural basis for allosteric coupling at the membrane-protein interface in Gloeobacter violaceus ligand-gated ion channel (GLIC)
-
24338475, .;():–.
-
Velisetty P, Chalamalasetti SV, Chakrapani S, Structural basis for allosteric coupling at the membrane-protein interface in Gloeobacter violaceus ligand-gated ion channel (GLIC). J Biol Chem. 2014;289(5):3013–25. doi: 10.1074/jbc.M113.52305024338475.
-
(2014)
J Biol Chem
, vol.289
, Issue.5
, pp. 3013-3025
-
-
Velisetty, P.1
Chalamalasetti, S.V.2
Chakrapani, S.3
-
61
-
-
79953845449
-
A versatile and efficient high-throughput cloning tool for structural biology
-
21410291, .;():–.
-
Geertsma ER, Dutzler R, A versatile and efficient high-throughput cloning tool for structural biology. Biochemistry. 2011;50(15):3272–8. doi: 10.1021/bi200178z21410291.
-
(2011)
Biochemistry
, vol.50
, Issue.15
, pp. 3272-3278
-
-
Geertsma, E.R.1
Dutzler, R.2
-
62
-
-
0029843417
-
Heteromultimeric CLC chloride channels with novel properties
-
8917596, .;():–.
-
Lorenz C, Pusch M, Jentsch TJ, Heteromultimeric CLC chloride channels with novel properties. Proc Natl Acad Sci U S A. 1996;93(23):13362–6. 8917596.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, Issue.23
, pp. 13362-13366
-
-
Lorenz, C.1
Pusch, M.2
Jentsch, T.J.3
-
63
-
-
0033103174
-
A new ER trafficking signal regulates the subunit stoichiometry of plasma membrane K(ATP) channels
-
10197533, .;():–.
-
Zerangue N, Schwappach B, Jan YN, Jan LY, A new ER trafficking signal regulates the subunit stoichiometry of plasma membrane K(ATP) channels. Neuron. 1999;22(3):537–48. 10197533.
-
(1999)
Neuron
, vol.22
, Issue.3
, pp. 537-548
-
-
Zerangue, N.1
Schwappach, B.2
Jan, Y.N.3
Jan, L.Y.4
-
64
-
-
0037196236
-
Achieving optimal expression for single channel recording: a plasmid ratio approach to the expression of alpha 1 glycine receptors in HEK293 cells
-
11772442, .;():–.
-
Groot-Kormelink PJ, Beato M, Finotti C, Harvey RJ, Sivilotti LG, Achieving optimal expression for single channel recording: a plasmid ratio approach to the expression of alpha 1 glycine receptors in HEK293 cells. J Neurosci Methods. 2002;113(2):207–14. 11772442.
-
(2002)
J Neurosci Methods
, vol.113
, Issue.2
, pp. 207-214
-
-
Groot-Kormelink, P.J.1
Beato, M.2
Finotti, C.3
Harvey, R.J.4
Sivilotti, L.G.5
-
65
-
-
0027879008
-
Automatic Processing of Rotation Diffraction Data from Crystals of Initially Unknown Symmetry and Cell Constants
-
.;():–.
-
Kabsch W, Automatic Processing of Rotation Diffraction Data from Crystals of Initially Unknown Symmetry and Cell Constants. J Appl Cryst. 1993;26(6):795–800.
-
(1993)
J Appl Cryst
, vol.26
, Issue.6
, pp. 795-800
-
-
Kabsch, W.1
-
66
-
-
0028103275
-
The CCP4 Suite: Programs for X-ray crystallography
-
15299374, .;:–.
-
CCP4Collaborative Computational Project Nr. 4The CCP4 Suite: Programs for X-ray crystallography. Acta Crystallogr D. 1994;50:760–3. 15299374
-
(1994)
Acta Crystallogr D
, vol.50
, pp. 760-763
-
-
-
67
-
-
34447508216
-
Phaser crystallographic software
-
.;:–
-
McCoy RWG-K A. J., Adams P. D., Winn M. D., Storoni L.C., Read R.J., Phaser crystallographic software. J Appl Cryst. 2007;40:658–74
-
(2007)
J Appl Cryst
, vol.40
, pp. 658-674
-
-
McCoy RWG-K, A.J.1
Adams, P.D.2
Winn, M.D.3
Storoni, L.C.4
Read, R.J.5
-
68
-
-
77949535720
-
Features and development of Coot
-
20383002, .;():–.
-
Emsley P, Lohkamp B, Scott WG, Cowtan K, Features and development of Coot. Acta Crystallogr D Biol Crystallogr. 2010;66(Pt 4):486–501. 20383002. doi: 10.1107/S0907444910007493
-
(2010)
Acta Crystallogr D Biol Crystallogr
, vol.66
, pp. 486-501
-
-
Emsley, P.1
Lohkamp, B.2
Scott, W.G.3
Cowtan, K.4
-
69
-
-
14244272868
-
PHENIX: building new software for automated crystallographic structure determination
-
12393927, ..;():–.
-
Adams PD, Grosse-Kunstleve RW, Hung LW, Ioerger TR, McCoy AJ, Moriarty NW, et al. PHENIX: building new software for automated crystallographic structure determination. Acta Crystallogr D Biol Crystallogr. 2002;58(Pt 11):1948–54. 12393927.
-
(2002)
Acta Crystallogr D Biol Crystallogr
, vol.58
, pp. 1948-1954
-
-
Adams, P.D.1
Grosse-Kunstleve, R.W.2
Hung, L.W.3
Ioerger, T.R.4
McCoy, A.J.5
Moriarty, N.W.6
-
70
-
-
0030404988
-
HOLE: a program for the analysis of the pore dimensions of ion channel structural models
-
9195488, .;():–, 76.
-
Smart OS, Neduvelil JG, Wang X, Wallace BA, Sansom MS, HOLE: a program for the analysis of the pore dimensions of ion channel structural models. J Mol Graph. 1996;14(6):354–60, 76. 9195488.
-
(1996)
J Mol Graph
, vol.14
, Issue.6
, pp. 354-360
-
-
Smart, O.S.1
Neduvelil, J.G.2
Wang, X.3
Wallace, B.A.4
Sansom, M.S.5
-
71
-
-
84861840835
-
High-precision isothermal titration calorimetry with automated peak-shape analysis
-
22530732, .;():–.
-
Keller S, Vargas C, Zhao H, Piszczek G, Brautigam CA, Schuck P, High-precision isothermal titration calorimetry with automated peak-shape analysis. Anal Chem. 2012;84(11):5066–73. doi: 10.1021/ac300752222530732.
-
(2012)
Anal Chem
, vol.84
, Issue.11
, pp. 5066-5073
-
-
Keller, S.1
Vargas, C.2
Zhao, H.3
Piszczek, G.4
Brautigam, C.A.5
Schuck, P.6
|