Mutation causing severe myasthenia reveals functional asymmetry of AChR signature cystine loops in agonist binding and gating

Journal of Clinical Investigation

Volumn 111, Issue 4, 2003, Pages 497-505

  Shen, Xin Ming ^a   Ohno, Kinji ^a   Tsujino, Akira ^a   Brengman, Joan M ^a   Gingold, Monique ^b   Sine, Steven M ^a   Engel, Andrew G ^a  

^a MAYO CLINIC   (United States)

^b Childrens Neurology Services   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCHOLINE; CHOLINERGIC RECEPTOR; CYSTINE; LEUCINE; VALINE;

ARTICLE; BETA CHAIN; BINDING AFFINITY; CASE REPORT; CHANNEL GATING; CONTROLLED STUDY; CRYSTAL STRUCTURE; HUMAN; HUMAN CELL; HUMAN TISSUE; MUTATION; MYASTHENIA; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; RECEPTOR BINDING; RECEPTOR UPREGULATION; SYNAPTIC TRANSMISSION;

EID: 0037329589     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI16997     Document Type: Article

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