Molecular tuning of fast gating in pentameric ligand-gated ion channels

Proceedings of the National Academy of Sciences of the United States of America

Volumn 102, Issue 50, 2005, Pages 18207-18212

  Grutter, Thomas ^a   Prado De Carvalho, Lia ^a   Dufresne, Virginie ^a   Taly, Antoine ^a   Edelstein, Stuart J ^b   Changeux, Jean Pierre ^a  

^a INSTITUT PASTEUR   (France)

^b UNIVERSITY OF GENEVA   (Switzerland)

Author keywords

Allosteric proteins; Chimeric receptor; Cys loop receptor; Transition state

Indexed keywords

ACETYLCHOLINE; AMINO ACID; GLYCINE; GLYCINE RECEPTOR; MEMBRANE PROTEIN; NICOTINIC RECEPTOR;

ALLOSTERISM; ANIMAL CELL; ARTICLE; BINDING SITE; CHANNEL GATING; CHICKEN; CHIMERA; CONTROLLED STUDY; EXTRACELLULAR AGONIST BINDING DOMAIN; HUMAN; HUMAN CELL; ION TRANSPORT; LIGAND BINDING; MOLECULAR BIOLOGY; MOLECULAR MECHANICS; MOLECULAR STABILITY; NEUROTRANSMISSION; NEUROTRANSMITTER RELEASE; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; PROTEIN DOMAIN; RECEPTOR BINDING; STRUCTURE ANALYSIS; SYNAPTIC TRANSMISSION;

ACETYLCHOLINE; AMINO ACID SEQUENCE; ANIMALS; BUNGAROTOXINS; CELL LINE; CHICKENS; HUMANS; IODINE RADIOISOTOPES; ION CHANNEL GATING; KINETICS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS; NEUROTRANSMITTER AGENTS; PATCH-CLAMP TECHNIQUES; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, GLYCINE; RECEPTORS, NICOTINIC;

ANIMALIA;

EID: 29144514665     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0509024102     Document Type: Article

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