Inhibition of the Prokaryotic Pentameric Ligand-Gated Ion Channel ELIC by Divalent Cations

PLoS Biology

Volumn 10, Issue 11, 2012, Pages

  Zimmermann, Iwan ^a   Marabelli, Alessandro ^b   Bertozzi, Carlo ^a   Sivilotti, Lucia G ^b   Dutzler, Raimund ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ION; CARBOXYLIC ACID; DIVALENT CATION; ION CHANNEL; MERCAPTAMINE; NEUROTRANSMITTER RECEPTOR; PENTAMERIC LIGAND GATED ION CHANNEL; PENTAMERIC LIGAND GATED ION CHANNEL ELIC; UNCLASSIFIED DRUG; ZINC ION;

ALLOSTERISM; ARTICLE; BINDING SITE; CALCIUM BINDING; CONTROLLED STUDY; CRYSTAL STRUCTURE; ELECTROPHYSIOLOGY; MUTAGENESIS; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN FAMILY; PROTEIN INTERACTION; PROTEIN STRUCTURE; PROTEIN SUBUNIT; SEQUENCE HOMOLOGY; X RAY CRYSTALLOGRAPHY;

ACETYLCHOLINE; ALLOSTERIC REGULATION; AMINO ACID SEQUENCE; ANIMALS; BARIUM; BINDING SITES; CALCIUM; CATIONS, DIVALENT; CELL MEMBRANE; CLONING, MOLECULAR; CRYSTALLOGRAPHY, X-RAY; CYSTEAMINE; ELECTROPHYSIOLOGICAL PHENOMENA; ESCHERICHIA COLI; HEK293 CELLS; HUMANS; ION CHANNEL GATING; LIGAND-GATED ION CHANNELS; MUTAGENESIS, SITE-DIRECTED; PATCH-CLAMP TECHNIQUES; PROKARYOTIC CELLS; PROTEIN INTERACTION MAPPING; PROTEIN STRUCTURE, TERTIARY; XENOPUS LAEVIS; ZINC;

PROKARYOTA;

EID: 84870266525     PISSN: 15449173     EISSN: 15457885     Source Type: Journal    
DOI: 10.1371/journal.pbio.1001429     Document Type: Article

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