-
1
-
-
0016140360
-
Structure of human plasma prealbumin at 2-5 a resolution. A preliminary report on the polypeptide chain conformation, quaternary structure and thyroxine binding
-
Blake C.C., Geisow M.J., Swan I.D.A. Structure of human plasma prealbumin at 2-5 a resolution. A preliminary report on the polypeptide chain conformation, quaternary structure and thyroxine binding. J Mol Biol 1974, 88:1-12.
-
(1974)
J Mol Biol
, vol.88
, pp. 1-12
-
-
Blake, C.C.1
Geisow, M.J.2
Swan, I.D.A.3
-
2
-
-
0021807498
-
High prealbumin and transferrin mRNA levels in the choroid plexus of rat brain
-
Dickson P.W., Aldred A.R., Marley P.D., Tu G.F., Howlett G.J., Schreiber G. High prealbumin and transferrin mRNA levels in the choroid plexus of rat brain. Biochem Biophys Res Commun 1985, 127:890-895.
-
(1985)
Biochem Biophys Res Commun
, vol.127
, pp. 890-895
-
-
Dickson, P.W.1
Aldred, A.R.2
Marley, P.D.3
Tu, G.F.4
Howlett, G.J.5
Schreiber, G.6
-
3
-
-
0026468669
-
Interactions of retinol with binding proteins: studies with retinol-binding protein and with transthyretin
-
Noy N., Slosberg E., Scarlata S. Interactions of retinol with binding proteins: studies with retinol-binding protein and with transthyretin. Biochemistry 1992, 31:11118-11124.
-
(1992)
Biochemistry
, vol.31
, pp. 11118-11124
-
-
Noy, N.1
Slosberg, E.2
Scarlata, S.3
-
4
-
-
59649105575
-
Pathogenesis of and therapeutic strategies to ameliorate the transthyretin amyloidoses
-
Sekijima Y., Kelly J.W., Ikeda S. Pathogenesis of and therapeutic strategies to ameliorate the transthyretin amyloidoses. Curr Pharm Des 2008, 14:3219-3230.
-
(2008)
Curr Pharm Des
, vol.14
, pp. 3219-3230
-
-
Sekijima, Y.1
Kelly, J.W.2
Ikeda, S.3
-
5
-
-
0020519870
-
Frequency and distribution of senile cardiovascular amyloid. A clinicopathologic correlation.
-
Cornwell III G.G., Murdoch W.L., Kyle R.A., Westermark P., Pitkanen P. Frequency and distribution of senile cardiovascular amyloid. A clinicopathologic correlation. Am J Med 1983, 75:618-623.
-
(1983)
Am J Med
, vol.75
, pp. 618-623
-
-
Cornwell, G.G.1
Murdoch, W.L.2
Kyle, R.A.3
Westermark, P.4
Pitkanen, P.5
-
6
-
-
0025278448
-
Fibril in senile systemic amyloidosis is derived from normal transthyretin
-
Westermark P., Sletten K., Johansson B., Cornwell III G.G. Fibril in senile systemic amyloidosis is derived from normal transthyretin. Proc Natl Acad Sci U S A 1990, 87:2843-2845.
-
(1990)
Proc Natl Acad Sci U S A
, vol.87
, pp. 2843-2845
-
-
Westermark, P.1
Sletten, K.2
Johansson, B.3
Cornwell, G.G.4
-
7
-
-
0242407579
-
Tabulation of human transthyretin (TTR) variants 2003
-
Connors L.H., Lim A., Prokaeva T., Roskens V.A., Costello C.E. Tabulation of human transthyretin (TTR) variants 2003. Amyloid 2003, 10:160-184.
-
(2003)
Amyloid
, vol.10
, pp. 160-184
-
-
Connors, L.H.1
Lim, A.2
Prokaeva, T.3
Roskens, V.A.4
Costello, C.E.5
-
8
-
-
14044249894
-
Haplotypes and DNA sequence variation within and surrounding the transthyretin gene: genotype-phenotype correlations in familial amyloid polyneuropathy (V30M) in Portugal and Sweden
-
Soares M.L., Coelho T., Sousa A., Holmgren G., Saraiva M.J., Kastner D.L., et al. Haplotypes and DNA sequence variation within and surrounding the transthyretin gene: genotype-phenotype correlations in familial amyloid polyneuropathy (V30M) in Portugal and Sweden. Eur J Hum Genet 2004, 12:225-237.
-
(2004)
Eur J Hum Genet
, vol.12
, pp. 225-237
-
-
Soares, M.L.1
Coelho, T.2
Sousa, A.3
Holmgren, G.4
Saraiva, M.J.5
Kastner, D.L.6
-
9
-
-
29244481662
-
L55P transthyretin accelerates subunit exchange and leads to rapid formation of hybrid tetramers
-
Keetch C.A., Bromley E.H., McCammon M.G., Wang N., Christodoulou J., Robinson C.V. L55P transthyretin accelerates subunit exchange and leads to rapid formation of hybrid tetramers. J Biol Chem 2005, 280:41667-41674.
-
(2005)
J Biol Chem
, vol.280
, pp. 41667-41674
-
-
Keetch, C.A.1
Bromley, E.H.2
McCammon, M.G.3
Wang, N.4
Christodoulou, J.5
Robinson, C.V.6
-
10
-
-
1542357685
-
Tissue damage in the amyloidoses: transthyretin monomers and nonnative oligomers are the major cytotoxic species in tissue culture
-
Reixach N., Deechongkit S., Jiang X., Kelly J.W., Buxbaum J.N. Tissue damage in the amyloidoses: transthyretin monomers and nonnative oligomers are the major cytotoxic species in tissue culture. Proc Natl Acad Sci U S A 2004, 101:2817-2822.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 2817-2822
-
-
Reixach, N.1
Deechongkit, S.2
Jiang, X.3
Kelly, J.W.4
Buxbaum, J.N.5
-
11
-
-
0037473750
-
Prevention of transthyretin amyloid disease by changing protein misfolding energetics
-
Hammarstrom P., Wiseman R.L., Powers E.T., Kelly J.W. Prevention of transthyretin amyloid disease by changing protein misfolding energetics. Science 2003, 299:713-716.
-
(2003)
Science
, vol.299
, pp. 713-716
-
-
Hammarstrom, P.1
Wiseman, R.L.2
Powers, E.T.3
Kelly, J.W.4
-
12
-
-
84906048507
-
An overview of drugs currently under investigation for the treatment of transthyretin-related hereditary amyloidosis
-
Obici L., Merlini G. An overview of drugs currently under investigation for the treatment of transthyretin-related hereditary amyloidosis. Expert Opin Investig Drugs 2014, 23:1239-1251.
-
(2014)
Expert Opin Investig Drugs
, vol.23
, pp. 1239-1251
-
-
Obici, L.1
Merlini, G.2
-
13
-
-
84907998488
-
Beneficial properties of natural phenols: highlight on protection against pathological conditions associated with amyloid aggregation
-
Stefani M., Rigacci S. Beneficial properties of natural phenols: highlight on protection against pathological conditions associated with amyloid aggregation. Biofactors 2014, 40:482-493.
-
(2014)
Biofactors
, vol.40
, pp. 482-493
-
-
Stefani, M.1
Rigacci, S.2
-
15
-
-
33744807433
-
Mediterranean diet and risk for Alzheimer's disease
-
Scarmeas N.Y., Stern M.X., Tang R., Mayeux J.A., Luchsinger J.A. Mediterranean diet and risk for Alzheimer's disease. Ann Neurol 2006, 59:912-921.
-
(2006)
Ann Neurol
, vol.59
, pp. 912-921
-
-
Scarmeas, N.Y.1
Stern, M.X.2
Tang, R.3
Mayeux, J.A.4
Luchsinger, J.A.5
-
17
-
-
77954661025
-
Oleuropein aglycon prevents cytotoxic amyloid aggregation of human amylin
-
Rigacci S., Guidotti V., Bucciantini M., Parri M., Nediani C., Cerbai E., et al. Oleuropein aglycon prevents cytotoxic amyloid aggregation of human amylin. J Nutr Biochem 2010, 21:726-735.
-
(2010)
J Nutr Biochem
, vol.21
, pp. 726-735
-
-
Rigacci, S.1
Guidotti, V.2
Bucciantini, M.3
Parri, M.4
Nediani, C.5
Cerbai, E.6
-
18
-
-
82055197196
-
Aβ(1-42) aggregates into non-toxic amyloid assemblies in the presence of the natural polyphenol oleuropein aglycon
-
Rigacci S., Guidotti V., Bucciantini M., Nichino D., Relini A., Berti A., et al. Aβ(1-42) aggregates into non-toxic amyloid assemblies in the presence of the natural polyphenol oleuropein aglycon. Curr Alzheimer Res 2011, 8:841-852.
-
(2011)
Curr Alzheimer Res
, vol.8
, pp. 841-852
-
-
Rigacci, S.1
Guidotti, V.2
Bucciantini, M.3
Nichino, D.4
Relini, A.5
Berti, A.6
-
19
-
-
79953707326
-
Oleuropein and derivatives from olives as tau aggregation inhibitors
-
Daccache A., Lion C., Sibille N., Gerard M., Slomianny C., Lippens G., et al. Oleuropein and derivatives from olives as tau aggregation inhibitors. Neurochem Int 2011, 58:700-707.
-
(2011)
Neurochem Int
, vol.58
, pp. 700-707
-
-
Daccache, A.1
Lion, C.2
Sibille, N.3
Gerard, M.4
Slomianny, C.5
Lippens, G.6
-
20
-
-
84874778760
-
Oleuropein aglycone protects transgenic C. elegans strains expressing Aβ42 by reducing plaque load and motor deficit
-
Diomede L., Rigacci S., Romeo M., Stefani M., Salmona M. Oleuropein aglycone protects transgenic C. elegans strains expressing Aβ42 by reducing plaque load and motor deficit. PLoS One 2013, 8.
-
(2013)
PLoS One
, vol.8
-
-
Diomede, L.1
Rigacci, S.2
Romeo, M.3
Stefani, M.4
Salmona, M.5
-
21
-
-
84922840562
-
Oleuropein aglycone protects against pyroglutamylated-3 amyloid-ß toxicity: biochemical, epigenetic and functional correlates
-
Luccarini I., Grossi C., Rigacci S., Coppi E., Pugliese A.M., Pantano D., et al. Oleuropein aglycone protects against pyroglutamylated-3 amyloid-ß toxicity: biochemical, epigenetic and functional correlates. Neurobiol Aging 2015, 36:648-663.
-
(2015)
Neurobiol Aging
, vol.36
, pp. 648-663
-
-
Luccarini, I.1
Grossi, C.2
Rigacci, S.3
Coppi, E.4
Pugliese, A.M.5
Pantano, D.6
-
22
-
-
79952796718
-
Aromatic small molecules remodel toxic soluble oligomers of amyloid beta through three independent pathways
-
Ladiwala A.R., Dordick J.S., Tessier P.M. Aromatic small molecules remodel toxic soluble oligomers of amyloid beta through three independent pathways. J Biol Chem 2011, 286:3209-3218.
-
(2011)
J Biol Chem
, vol.286
, pp. 3209-3218
-
-
Ladiwala, A.R.1
Dordick, J.S.2
Tessier, P.M.3
-
23
-
-
77954847105
-
The crystal structure of the green tea polyphenol (-)-epigallocatechin gallate-transthyretin complex reveals a novel binding site distinct from the thyroxine binding site
-
Miyata M., Sato T., Kugimiya M., Sho M., Nakamura T., Ikemizu S., et al. The crystal structure of the green tea polyphenol (-)-epigallocatechin gallate-transthyretin complex reveals a novel binding site distinct from the thyroxine binding site. Biochemistry 2010, 49:6104-6114.
-
(2010)
Biochemistry
, vol.49
, pp. 6104-6114
-
-
Miyata, M.1
Sato, T.2
Kugimiya, M.3
Sho, M.4
Nakamura, T.5
Ikemizu, S.6
-
24
-
-
84868592337
-
Dietary curcumin counteracts extracellular transthyretin deposition: insights on the mechanism of amyloid inhibition
-
Ferreira N., Santos S.A., Domingues M.R., Saraiva M.J., Almeida M.R. Dietary curcumin counteracts extracellular transthyretin deposition: insights on the mechanism of amyloid inhibition. Biochim Biophys Acta 1832, 2013:39-45.
-
(1832)
Biochim Biophys Acta
, vol.2013
, pp. 39-45
-
-
Ferreira, N.1
Santos, S.A.2
Domingues, M.R.3
Saraiva, M.J.4
Almeida, M.R.5
-
25
-
-
79960910835
-
Natural polyphenols inhibit different steps of the process of transthyretin (TTR) amyloid fibril formation
-
Ferreira N., Saraiva M.J., Almeida M.R. Natural polyphenols inhibit different steps of the process of transthyretin (TTR) amyloid fibril formation. FEBS Lett 2011, 585:2424-2430.
-
(2011)
FEBS Lett
, vol.585
, pp. 2424-2430
-
-
Ferreira, N.1
Saraiva, M.J.2
Almeida, M.R.3
-
26
-
-
1342346691
-
Cardiac physiology at the cellular level: use of cultured HL-1 cardiomyocytes for studies of cardiac muscle cell structure and function
-
White S.M., Constantin P.E., Claycomb W.E. Cardiac physiology at the cellular level: use of cultured HL-1 cardiomyocytes for studies of cardiac muscle cell structure and function. Am J Physiol Heart Circ Physiol 2004, 286:H823-H829.
-
(2004)
Am J Physiol Heart Circ Physiol
, vol.286
, pp. H823-H829
-
-
White, S.M.1
Constantin, P.E.2
Claycomb, W.E.3
-
27
-
-
84893364949
-
Proteolytic cleavage of Ser52Pro variant transthyretin triggers its amyloid fibrillogenesis.
-
Mangione P.P., Porcari R., Gillmore J.D., Pucci P., Monti M., Porcari M., et al. Proteolytic cleavage of Ser52Pro variant transthyretin triggers its amyloid fibrillogenesis. Proc Natl Acad Sci U S A 2014, 111:1539-1544.
-
(2014)
Proc Natl Acad Sci U S A
, vol.111
, pp. 1539-1544
-
-
Mangione, P.P.1
Porcari, R.2
Gillmore, J.D.3
Pucci, P.4
Monti, M.5
Porcari, M.6
-
28
-
-
16744366300
-
"In vitro" amyloid fibril formation from transthyretin: the influence of ions and the amyloidogenicity of TTR variants
-
Bonifacio M.J., Sakaki Y., Saraiva M.J. "In vitro" amyloid fibril formation from transthyretin: the influence of ions and the amyloidogenicity of TTR variants. Biochim Biophys Acta 1996, 1316:35-42.
-
(1996)
Biochim Biophys Acta
, vol.1316
, pp. 35-42
-
-
Bonifacio, M.J.1
Sakaki, Y.2
Saraiva, M.J.3
-
29
-
-
3343003514
-
Techniques to study amyloid fibril formation in vitro
-
Nilsson M.R. Techniques to study amyloid fibril formation in vitro. Methods 2004, 34:151-160.
-
(2004)
Methods
, vol.34
, pp. 151-160
-
-
Nilsson, M.R.1
-
30
-
-
33845192482
-
Congo red and protein aggregation in neurodegenerative diseases
-
Frid P., Anisimov S.V., Popovic N. Congo red and protein aggregation in neurodegenerative diseases. Brain Res Rev 2007, 53:135-160.
-
(2007)
Brain Res Rev
, vol.53
, pp. 135-160
-
-
Frid, P.1
Anisimov, S.V.2
Popovic, N.3
-
31
-
-
0037112480
-
Functional expression of the hyperpolarization-activated, non-selective cation current I(f) in immortalized HL-1 cardiomyocytes
-
Sartiani L., Bochet P., Cerbai E., Mugelli A., Fischmeister R. Functional expression of the hyperpolarization-activated, non-selective cation current I(f) in immortalized HL-1 cardiomyocytes. J Physiol 2002, 545:81-92.
-
(2002)
J Physiol
, vol.545
, pp. 81-92
-
-
Sartiani, L.1
Bochet, P.2
Cerbai, E.3
Mugelli, A.4
Fischmeister, R.5
-
32
-
-
84881271682
-
A molecular imaging analysis of Cx43 association with Cdo during skeletal myoblast differentiation
-
Nosi D., Mercatelli R., Chellini F., Soria S., Pini A., Formigli L., et al. A molecular imaging analysis of Cx43 association with Cdo during skeletal myoblast differentiation. J Biophotonics 2012, 6:612-661.
-
(2012)
J Biophotonics
, vol.6
, pp. 612-661
-
-
Nosi, D.1
Mercatelli, R.2
Chellini, F.3
Soria, S.4
Pini, A.5
Formigli, L.6
-
33
-
-
84865323237
-
Fourier transform infrared spectroscopy of intrinsically disordered proteins: measurement procedures and data analyses
-
Natalello A., Ami D., Doglia S.M. Fourier transform infrared spectroscopy of intrinsically disordered proteins: measurement procedures and data analyses. Methods Mol Biol 2012, 895:229-244.
-
(2012)
Methods Mol Biol
, vol.895
, pp. 229-244
-
-
Natalello, A.1
Ami, D.2
Doglia, S.M.3
-
34
-
-
84859416802
-
Structure, stability, and aggregation of β-2 microglobulin mutants: insights from a Fourier transform infrared study in solution and in the crystalline state
-
Ami D., Ricagno S., Bolognesi M., Bellotti V., Doglia S.M., Natalello A. Structure, stability, and aggregation of β-2 microglobulin mutants: insights from a Fourier transform infrared study in solution and in the crystalline state. Biophys J 2012, 102:1676-1684.
-
(2012)
Biophys J
, vol.102
, pp. 1676-1684
-
-
Ami, D.1
Ricagno, S.2
Bolognesi, M.3
Bellotti, V.4
Doglia, S.M.5
Natalello, A.6
-
35
-
-
0022463740
-
Resolution-enhanced Fourier transform infrared spectroscopy of enzymes
-
Susi H., Byler D.M. Resolution-enhanced Fourier transform infrared spectroscopy of enzymes. Methods Enzymol 1986, 130:290-311.
-
(1986)
Methods Enzymol
, vol.130
, pp. 290-311
-
-
Susi, H.1
Byler, D.M.2
-
36
-
-
16244362365
-
Second derivative tryptophan fluorescence spectroscopy as a tool to characterize partially unfolded intermediates of proteins
-
Kumar V., Sharma V.K., Kalonia D.S. Second derivative tryptophan fluorescence spectroscopy as a tool to characterize partially unfolded intermediates of proteins. Int J Pharm 2005, 294:193-199.
-
(2005)
Int J Pharm
, vol.294
, pp. 193-199
-
-
Kumar, V.1
Sharma, V.K.2
Kalonia, D.S.3
-
37
-
-
0038047044
-
Structural transformations of oligomeric intermediates in the fibrillation of the immunoglobulin light chain LEN
-
Souillac P.O., Uversky V.N., Fink A.L. Structural transformations of oligomeric intermediates in the fibrillation of the immunoglobulin light chain LEN. Biochemistry 2003, 42:8094-8104.
-
(2003)
Biochemistry
, vol.42
, pp. 8094-8104
-
-
Souillac, P.O.1
Uversky, V.N.2
Fink, A.L.3
-
38
-
-
77953613891
-
Effects of dietary extra-virgin olive oil on behaviour and brain biochemical parameters in ageing rats
-
Pitozzi V., Jacomelli M., Zaid M., Luceri C., Bigagli E., Lodovici M., et al. Effects of dietary extra-virgin olive oil on behaviour and brain biochemical parameters in ageing rats. Br J Nutr 2010, 11:1674-1683.
-
(2010)
Br J Nutr
, vol.11
, pp. 1674-1683
-
-
Pitozzi, V.1
Jacomelli, M.2
Zaid, M.3
Luceri, C.4
Bigagli, E.5
Lodovici, M.6
-
39
-
-
84855815138
-
Extra virgin olive oil improves learning and memory in SAMP8 mice
-
Farr S.A., Price TO, Dominguez L.J., Motisi A., Saiano F., Niehoff M.L., et al. Extra virgin olive oil improves learning and memory in SAMP8 mice. J Alzheimers Dis 2012, 28:81-92.
-
(2012)
J Alzheimers Dis
, vol.28
, pp. 81-92
-
-
Farr, S.A.1
Price, T.O.2
Dominguez, L.J.3
Motisi, A.4
Saiano, F.5
Niehoff, M.L.6
-
40
-
-
84896891508
-
Olive leaf extract attenuates obesity in high-fat diet-fed mice by modulating the expression of molecules involved in adipogenesis and thermogenesis
-
Shen Y., Song S.J., Keum N., Park T. Olive leaf extract attenuates obesity in high-fat diet-fed mice by modulating the expression of molecules involved in adipogenesis and thermogenesis. Evid Based Complement Altern Med 2012, 2014:971890.
-
(2012)
Evid Based Complement Altern Med
, vol.2014
, pp. 971890
-
-
Shen, Y.1
Song, S.J.2
Keum, N.3
Park, T.4
-
41
-
-
77954543394
-
Cardioprotective and neuroprotective roles of oleuropein in olive
-
Omar S.H. Cardioprotective and neuroprotective roles of oleuropein in olive. Saudi Pharm J 2010, 18:111-121.
-
(2010)
Saudi Pharm J
, vol.18
, pp. 111-121
-
-
Omar, S.H.1
-
42
-
-
0030004644
-
The acid-mediated denaturation pathway of transthyretin yields a conformational intermediate that can self-assemble into amyloid
-
Lai Z., Colón W., Kelly J.W. The acid-mediated denaturation pathway of transthyretin yields a conformational intermediate that can self-assemble into amyloid. Biochemistry 1996, 35:6470-6482.
-
(1996)
Biochemistry
, vol.35
, pp. 6470-6482
-
-
Lai, Z.1
Colón, W.2
Kelly, J.W.3
-
43
-
-
84866318129
-
Distinct annular oligomers captured along the assembly and disassembly pathways of TransthyretinAmyloid protofibrils
-
Pires R.H., Karsai Á., Saraiva M.J., Damas A.M., Kellermayer M.S. Distinct annular oligomers captured along the assembly and disassembly pathways of TransthyretinAmyloid protofibrils. PLoS One 2012, 7.
-
(2012)
PLoS One
, vol.7
-
-
Pires, R.H.1
Karsai, Á.2
Saraiva, M.J.3
Damas, A.M.4
Kellermayer, M.S.5
-
44
-
-
33746780089
-
Fourier transform infrared spectroscopy provides a fingerprint for the tetramer and for the aggregates of transthyretin
-
Cordeiro Y., Kraineva J., Suarez M.C., Tempesta A.G., Kelly J.W., Silva J.L., et al. Fourier transform infrared spectroscopy provides a fingerprint for the tetramer and for the aggregates of transthyretin. Biophys J 2006, 91:957-967.
-
(2006)
Biophys J
, vol.91
, pp. 957-967
-
-
Cordeiro, Y.1
Kraineva, J.2
Suarez, M.C.3
Tempesta, A.G.4
Kelly, J.W.5
Silva, J.L.6
-
45
-
-
9344243513
-
FT-IR reveals structural differences between native beta-sheet proteins and amyloid fibrils
-
Zandomeneghi G., Krebs M.R., McCammon M.G., Fändrich M. FT-IR reveals structural differences between native beta-sheet proteins and amyloid fibrils. Protein Sci 2004, 13:3314-3321.
-
(2004)
Protein Sci
, vol.13
, pp. 3314-3321
-
-
Zandomeneghi, G.1
Krebs, M.R.2
McCammon, M.G.3
Fändrich, M.4
-
46
-
-
0024653815
-
Acrylamide quenching of tryptophan photochemistry and photophysics
-
Tallmadge D.H., Huebner J.S., Borkman R.F. Acrylamide quenching of tryptophan photochemistry and photophysics. Photochem Photobiol 1989, 49:381-386.
-
(1989)
Photochem Photobiol
, vol.49
, pp. 381-386
-
-
Tallmadge, D.H.1
Huebner, J.S.2
Borkman, R.F.3
-
47
-
-
84908211476
-
Toxicity of protein oligomers is rationalized by a function combining size and surface hydrophobicity
-
Mannini B., Mulvihill E., Sgromo C., Cascella R., Khodarahmi R., Ramazzotti M., et al. Toxicity of protein oligomers is rationalized by a function combining size and surface hydrophobicity. ACS Chem Biol 2014, 9:2309-2317.
-
(2014)
ACS Chem Biol
, vol.9
, pp. 2309-2317
-
-
Mannini, B.1
Mulvihill, E.2
Sgromo, C.3
Cascella, R.4
Khodarahmi, R.5
Ramazzotti, M.6
-
48
-
-
84881327671
-
The polyphenol oleuropein aglycone protects TgCRND8 mice against Aß plaque pathology
-
Grossi C., Rigacci S., Ambrosini S., Ed Dami T., Luccarini I., Traini C., et al. The polyphenol oleuropein aglycone protects TgCRND8 mice against Aß plaque pathology. PLoS One 2013, 8.
-
(2013)
PLoS One
, vol.8
-
-
Grossi, C.1
Rigacci, S.2
Ambrosini, S.3
Ed Dami, T.4
Luccarini, I.5
Traini, C.6
-
49
-
-
84856545963
-
Toxic effects of amyloid fibrils on cell membranes: the importance of ganglioside GM1
-
Bucciantini M., Nosi D., Forzan M., Russo E., Calamai M., Pieri L., et al. Toxic effects of amyloid fibrils on cell membranes: the importance of ganglioside GM1. FASEB J 2012, 262:818-831.
-
(2012)
FASEB J
, vol.262
, pp. 818-831
-
-
Bucciantini, M.1
Nosi, D.2
Forzan, M.3
Russo, E.4
Calamai, M.5
Pieri, L.6
-
50
-
-
84906239240
-
How do membranes initiate Alzheimer's disease? Formation of toxic amyloid fibrils by the amyloid β-protein on ganglioside clusters
-
Matsuzaki K. How do membranes initiate Alzheimer's disease? Formation of toxic amyloid fibrils by the amyloid β-protein on ganglioside clusters. Acc Chem Res 2014, 478:2397-2404.
-
(2014)
Acc Chem Res
, vol.478
, pp. 2397-2404
-
-
Matsuzaki, K.1
-
51
-
-
28244495389
-
Natural antioxidants and neurodegenerative diseases
-
Bastianetto S., Quirion R. Natural antioxidants and neurodegenerative diseases. Front Biosci 2004, 9:3447-3452.
-
(2004)
Front Biosci
, vol.9
, pp. 3447-3452
-
-
Bastianetto, S.1
Quirion, R.2
-
52
-
-
20444403757
-
Prediction of "aggregation-prone" and "aggregation-susceptible" regions in proteins associated with neurodegenerative diseases
-
Pawar A.P., Dubay K.F., Zurdo J., Chiti F., Vendruscolo M., Dobson C.M. Prediction of "aggregation-prone" and "aggregation-susceptible" regions in proteins associated with neurodegenerative diseases. J Mol Biol 2005, 350:379-392.
-
(2005)
J Mol Biol
, vol.350
, pp. 379-392
-
-
Pawar, A.P.1
Dubay, K.F.2
Zurdo, J.3
Chiti, F.4
Vendruscolo, M.5
Dobson, C.M.6
-
53
-
-
79960291244
-
Mechanisms of transthyretin cardiomyocyte toxicity inhibition by resveratrol analogs
-
Bourgault S., Choi S., Buxbaum J.N., Kelly J.W., Price J.L., Reixach N. Mechanisms of transthyretin cardiomyocyte toxicity inhibition by resveratrol analogs. Biochem Biophys Res Commun 2011, 410:707-713.
-
(2011)
Biochem Biophys Res Commun
, vol.410
, pp. 707-713
-
-
Bourgault, S.1
Choi, S.2
Buxbaum, J.N.3
Kelly, J.W.4
Price, J.L.5
Reixach, N.6
-
54
-
-
84869109959
-
Green tea halts progression of cardiac transthyretin amyloidosis: an observational report
-
Kristen A.V., Lehrke S., Buss S., Mereles D., Steen H., Ehlermann P., et al. Green tea halts progression of cardiac transthyretin amyloidosis: an observational report. Clin Res Cardiol 2012, 101:805-813.
-
(2012)
Clin Res Cardiol
, vol.101
, pp. 805-813
-
-
Kristen, A.V.1
Lehrke, S.2
Buss, S.3
Mereles, D.4
Steen, H.5
Ehlermann, P.6
-
55
-
-
84938286982
-
Extracellular remodeling in patients with wild-type amyloidosis consuming epigallocatechin-3-gallate: preliminary results of T1 mapping by cardiac magnetic resonance imaging in a small single center study
-
Aus Dem Siepen F., SJ Buss, Andre F., Seitz S., Giannitsis E., Steen H., et al. Extracellular remodeling in patients with wild-type amyloidosis consuming epigallocatechin-3-gallate: preliminary results of T1 mapping by cardiac magnetic resonance imaging in a small single center study. Clin Res Cardiol 2015, 104:640-647.
-
(2015)
Clin Res Cardiol
, vol.104
, pp. 640-647
-
-
Aus Dem Siepen, F.1
Andre, F.2
Seitz, S.3
Giannitsis, E.4
Steen, H.5
-
56
-
-
84895458646
-
Oleuropein prevents doxorubicin-induced cardiomyopathy interfering with signaling molecules and cardiomyocyte metabolism
-
Andreadou I., Mikros E., Ioannidis K., Sigala F., Naka K., Kostidis S., et al. Oleuropein prevents doxorubicin-induced cardiomyopathy interfering with signaling molecules and cardiomyocyte metabolism. J Mol Cell Cardiol 2014, 69:4-16.
-
(2014)
J Mol Cell Cardiol
, vol.69
, pp. 4-16
-
-
Andreadou, I.1
Mikros, E.2
Ioannidis, K.3
Sigala, F.4
Naka, K.5
Kostidis, S.6
-
57
-
-
0037907526
-
Why is Leu55 → Pro55 transthyretin variant the mostamyloidogenic: insights from molecular dynamics simulations of transthyretin monomers
-
Yang M., Lei M., Huo S. Why is Leu55 → Pro55 transthyretin variant the mostamyloidogenic: insights from molecular dynamics simulations of transthyretin monomers. Protein Sci 2003, 12:1222-1231.
-
(2003)
Protein Sci
, vol.12
, pp. 1222-1231
-
-
Yang, M.1
Lei, M.2
Huo, S.3
-
58
-
-
8544272519
-
Inhibition of islet amyloid polypeptide fibril formation: a potential role for heteroaromatic interactions
-
Porat Y., Mazor Y., Efrat S., Gazit E. Inhibition of islet amyloid polypeptide fibril formation: a potential role for heteroaromatic interactions. Biochemistry 2004, 43:14454-14462.
-
(2004)
Biochemistry
, vol.43
, pp. 14454-14462
-
-
Porat, Y.1
Mazor, Y.2
Efrat, S.3
Gazit, E.4
-
59
-
-
33751249621
-
Phenol red interacts with the protofibril-like oligomers of an amyloidogenic hexapeptide NFGAIL through both hydrophobic and aromatic contacts
-
Wu C., Lei H., Wang Z., Zhang W., Duan Y. Phenol red interacts with the protofibril-like oligomers of an amyloidogenic hexapeptide NFGAIL through both hydrophobic and aromatic contacts. Biophys J 2006, 91:3664-3672.
-
(2006)
Biophys J
, vol.91
, pp. 3664-3672
-
-
Wu, C.1
Lei, H.2
Wang, Z.3
Zhang, W.4
Duan, Y.5
-
60
-
-
0036135139
-
A possible role for π-stacking in self-assembly of amyloid fibrils
-
Gazit E. A possible role for π-stacking in self-assembly of amyloid fibrils. FASEB J 2002, 16:77-83.
-
(2002)
FASEB J
, vol.16
, pp. 77-83
-
-
Gazit, E.1
-
61
-
-
33745096194
-
Inhibition of amyloid fibril formation by polyphenols: structural similarity and aromatic interactions as a common inhibition mechanism
-
Porat Y., Abramowitz A., Gazit E. Inhibition of amyloid fibril formation by polyphenols: structural similarity and aromatic interactions as a common inhibition mechanism. Chem Biol Drug Des 2006, 67:27-37.
-
(2006)
Chem Biol Drug Des
, vol.67
, pp. 27-37
-
-
Porat, Y.1
Abramowitz, A.2
Gazit, E.3
-
62
-
-
84928963185
-
PH-induced molecular shedding drives the formation of amyloid fibril-derived oligomers
-
Tipping K.W., Karamanos T.K., Jakhria T., Iadanza M.G., Goodchild S.C., Tuma R., et al. pH-induced molecular shedding drives the formation of amyloid fibril-derived oligomers. PNAS 2015, 112:5691-5696.
-
(2015)
PNAS
, vol.112
, pp. 5691-5696
-
-
Tipping, K.W.1
Karamanos, T.K.2
Jakhria, T.3
Iadanza, M.G.4
Goodchild, S.C.5
Tuma, R.6
-
63
-
-
56149110150
-
Transthyretin and amyloid in the islets of Langerhans in type-2 diabetes
-
Westermark G., Westermark P. Transthyretin and amyloid in the islets of Langerhans in type-2 diabetes. Exp Diabetes Res 2008, 2008:429274.
-
(2008)
Exp Diabetes Res
, vol.2008
, pp. 429274
-
-
Westermark, G.1
Westermark, P.2
-
64
-
-
84946475663
-
Targeting protein aggregation for the treatment of degenerative diseases
-
Eisele Y.S., Monteiro C., Fearns C., Encalada S.E., Wiseman R.L., Powers E.T., et al. Targeting protein aggregation for the treatment of degenerative diseases. Nat Rev Drug Discov 2015, 14:759-780.
-
(2015)
Nat Rev Drug Discov
, vol.14
, pp. 759-780
-
-
Eisele, Y.S.1
Monteiro, C.2
Fearns, C.3
Encalada, S.E.4
Wiseman, R.L.5
Powers, E.T.6
-
65
-
-
23944501270
-
Binding of amyloidogenic transthyretin to the plasma membrane alters membrane fluidity and induces neurotoxicity
-
Hou X., Richardson S.J., Aguilar M.I., Small D.H. Binding of amyloidogenic transthyretin to the plasma membrane alters membrane fluidity and induces neurotoxicity. Biochemistry 2005, 44:11618-11627.
-
(2005)
Biochemistry
, vol.44
, pp. 11618-11627
-
-
Hou, X.1
Richardson, S.J.2
Aguilar, M.I.3
Small, D.H.4
-
66
-
-
84862701723
-
Fibrillar α-synuclein and huntingtin exon 1 assemblies are toxic to the cells
-
Pieri L., Madiona K., Bousset L., Melki R. Fibrillar α-synuclein and huntingtin exon 1 assemblies are toxic to the cells. Biophys J 2012, 102:2894-2905.
-
(2012)
Biophys J
, vol.102
, pp. 2894-2905
-
-
Pieri, L.1
Madiona, K.2
Bousset, L.3
Melki, R.4
-
67
-
-
84899068704
-
Soluble Aβ oligomers are rapidly sequestered from brain ISF in vivo and bind GM1 ganglioside on cellular membranes
-
Hong S., Ostaszewski B.L., Yang T., O'Malley T.T., Jin M., Yanagisawa K., et al. Soluble Aβ oligomers are rapidly sequestered from brain ISF in vivo and bind GM1 ganglioside on cellular membranes. Neuron 2014, 82:308-319.
-
(2014)
Neuron
, vol.82
, pp. 308-319
-
-
Hong, S.1
Ostaszewski, B.L.2
Yang, T.3
O'Malley, T.T.4
Jin, M.5
Yanagisawa, K.6
-
68
-
-
38149054928
-
Cholesterol and anionic phospholipids increase the binding of amyloidogenic transthyretin to lipid membranes
-
Hou X., Mechler A., Martin L.L., Aguilar M.I., Small D.H. Cholesterol and anionic phospholipids increase the binding of amyloidogenic transthyretin to lipid membranes. Biochim Biophys Acta 1778, 2008:198-205.
-
(1778)
Biochim Biophys Acta
, vol.2008
, pp. 198-205
-
-
Hou, X.1
Mechler, A.2
Martin, L.L.3
Aguilar, M.I.4
Small, D.H.5
|