메뉴 건너뛰기




Volumn 6, Issue 2, 2016, Pages

Multiple layers of stress-induced regulation in tRNA biology

Author keywords

tRNA fragments; tRNA modification; tRNA processing; tRNA subcellular dynamics

Indexed keywords


EID: 84961644835     PISSN: None     EISSN: 20751729     Source Type: Journal    
DOI: 10.3390/life6020016     Document Type: Review
Times cited : (57)

References (142)
  • 1
    • 17044376304 scopus 로고    scopus 로고
    • GCN2 whets the appetite for amino acids
    • [CrossRef] [PubMed]
    • Dever, T.E.; Hinnebusch, A.G. GCN2 whets the appetite for amino acids. Mol. Cell 2005, 18, 141-142. [CrossRef] [PubMed]
    • (2005) Mol. Cell , vol.18 , pp. 141-142
    • Dever, T.E.1    Hinnebusch, A.G.2
  • 2
    • 79953147308 scopus 로고    scopus 로고
    • Apoptotic regulation and tRNA
    • [CrossRef] [PubMed]
    • Mei, Y.; Stonestrom, A.; Hou, Y.M.; Yang, X. Apoptotic regulation and tRNA. Protein Cell 2010, 1, 795-801. [CrossRef] [PubMed]
    • (2010) Protein Cell , vol.1 , pp. 795-801
    • Mei, Y.1    Stonestrom, A.2    Hou, Y.M.3    Yang, X.4
  • 3
    • 0030632048 scopus 로고    scopus 로고
    • The N-end rule pathway of protein degradation
    • [CrossRef] [PubMed]
    • Varshavsky, A. The N-end rule pathway of protein degradation. Genes Cells 1997, 2, 13-28. [CrossRef] [PubMed]
    • (1997) Genes Cells , vol.2 , pp. 13-28
    • Varshavsky, A.1
  • 4
    • 84877088375 scopus 로고    scopus 로고
    • Transfer RNA post-transcriptional processing, turnover, and subcellular dynamics in the yeast Saccharomyces cerevisiae
    • [CrossRef] [PubMed]
    • Hopper, A.K. Transfer RNA post-transcriptional processing, turnover, and subcellular dynamics in the yeast Saccharomyces cerevisiae. Genetics 2013, 194, 43-67. [CrossRef] [PubMed]
    • (2013) Genetics , vol.194 , pp. 43-67
    • Hopper, A.K.1
  • 5
    • 84906213108 scopus 로고    scopus 로고
    • tRNAs as regulators of biological processes
    • [CrossRef] [PubMed]
    • Raina, M.; Ibba, M. tRNAs as regulators of biological processes. Front. Genet. 2014, 5, 171. [CrossRef] [PubMed]
    • (2014) Front. Genet , vol.5 , pp. 171
    • Raina, M.1    Ibba, M.2
  • 6
    • 84924192559 scopus 로고    scopus 로고
    • Emerging roles of tRNA in adaptive translation, signalling dynamics and disease
    • [CrossRef] [PubMed]
    • Kirchner, S.; Ignatova, Z. Emerging roles of tRNA in adaptive translation, signalling dynamics and disease. Nat. Rev. Genet. 2015, 16, 98-112. [CrossRef] [PubMed]
    • (2015) Nat. Rev. Genet , vol.16 , pp. 98-112
    • Kirchner, S.1    Ignatova, Z.2
  • 7
    • 84961678866 scopus 로고    scopus 로고
    • Role of tRNA modifications in human diseases
    • [CrossRef] [PubMed]
    • Torres, A.G.; Batlle, E.; Ribas de Pouplana, L. Role of tRNA modifications in human diseases. Trends Mol. Med. 2014, 4914, 10. [CrossRef] [PubMed]
    • (2014) Trends Mol. Med , vol.4914 , pp. 10
    • Torres, A.G.1    Batlle, E.2    De Ribas Pouplana, L.3
  • 8
    • 84931575609 scopus 로고    scopus 로고
    • Controlling translation via modulation of tRNA levels
    • [CrossRef] [PubMed]
    • Wilusz, J.E. Controlling translation via modulation of tRNA levels. Wiley Interdiscip. Rev. RNA 2015, 6, 453-470. [CrossRef] [PubMed]
    • (2015) Wiley Interdiscip. Rev. RNA , vol.6 , pp. 453-470
    • Wilusz, J.E.1
  • 9
    • 84929410801 scopus 로고    scopus 로고
    • Quality control pathways for nucleus-encoded eukaryotic tRNA biosynthesis and subcellular trafficking
    • [CrossRef] [PubMed]
    • Hopper, A.K.; Huang, H.Y. Quality control pathways for nucleus-encoded eukaryotic tRNA biosynthesis and subcellular trafficking. Mol. Cell Biol. 2015, 35, 2052-2058. [CrossRef] [PubMed]
    • (2015) Mol. Cell Biol , vol.35 , pp. 2052-2058
    • Hopper, A.K.1    Huang, H.Y.2
  • 10
    • 77952891717 scopus 로고    scopus 로고
    • RNA metabolism and the pathogenesis of motor neuron diseases
    • [CrossRef] [PubMed]
    • Lemmens, R.; Moore, M.J.; Al-Chalabi, A.; Brown, R.H., Jr.; Robberecht, W. RNA metabolism and the pathogenesis of motor neuron diseases. Trends Neurosci. 2010, 33, 249-258. [CrossRef] [PubMed]
    • (2010) Trends Neurosci , vol.33 , pp. 249-258
    • Lemmens, R.1    Moore, M.J.2    Al-Chalabi, A.3    Brown, R.H.4    Robberecht, W.5
  • 12
    • 84947031580 scopus 로고    scopus 로고
    • Defects in tRNA anticodon loop 2'-O-methylation are implicated in nonsyndromic x-linked intellectual disability due to mutations in FTSJ1
    • [CrossRef] [PubMed]
    • Guy, M.P.; Shaw, M.; Weiner, C.L.; Hobson, L.; Stark, Z.; Rose, K.; Kalscheuer, V.M.; Gecz, J.; Phizicky, E.M. Defects in tRNA anticodon loop 2'-O-methylation are implicated in nonsyndromic x-linked intellectual disability due to mutations in FTSJ1. Hum. Mutat. 2015, 36, 1176-1187. [CrossRef] [PubMed]
    • (2015) Hum. Mutat , vol.36 , pp. 1176-1187
    • Guy, M.P.1    Shaw, M.2    Weiner, C.L.3    Hobson, L.4    Stark, Z.5    Rose, K.6    Kalscheuer, V.M.7    Gecz, J.8    Phizicky, E.M.9
  • 13
    • 75149181741 scopus 로고    scopus 로고
    • Pan, T. tRNA over-expression in breast cancer and functional consequences
    • [CrossRef] [PubMed]
    • Pavon-Eternod, M.; Gomes, S.; Geslain, R.; Dai, Q.; Rosner, M.R.; Pan, T. tRNA over-expression in breast cancer and functional consequences. Nucleic Acids Res. 2009, 37, 7268-7280. [CrossRef] [PubMed]
    • (2009) Nucleic Acids Res , vol.37 , pp. 7268-7280
    • Pavon-Eternod, M.1    Gomes, S.2    Geslain, R.3    Dai, Q.4    Rosner, M.R.5
  • 14
    • 84872870536 scopus 로고    scopus 로고
    • tRNA-derived microRNA modulates proliferation and the DNA damage response and is down-regulated in B cell lymphoma
    • [CrossRef] [PubMed]
    • Maute, R.L.; Schneider, C.; Sumazin, P.; Holmes, A.; Califano, A.; Basso, K.; Dalla-Favera, R. tRNA-derived microRNA modulates proliferation and the DNA damage response and is down-regulated in B cell lymphoma. Proc. Natl. Acad. Sci. USA 2013, 110, 1404-1409. [CrossRef] [PubMed]
    • (2013) Proc. Natl. Acad. Sci. USA , vol.110 , pp. 1404-1409
    • Maute, R.L.1    Schneider, C.2    Sumazin, P.3    Holmes, A.4    Califano, A.5    Basso, K.6    Dalla-Favera, R.7
  • 15
    • 84875465521 scopus 로고    scopus 로고
    • Overexpression of initiator methionine tRNA leads to global reprogramming of tRNA expression and increased proliferation in human epithelial cells
    • [CrossRef] [PubMed]
    • Pavon-Eternod, M.; Gomes, S.; Rosner, M.R.; Pan, T. Overexpression of initiator methionine tRNA leads to global reprogramming of tRNA expression and increased proliferation in human epithelial cells. RNA 2013, 19, 461-466. [CrossRef] [PubMed]
    • (2013) RNA , vol.19 , pp. 461-466
    • Pavon-Eternod, M.1    Gomes, S.2    Rosner, M.R.3    Pan, T.4
  • 16
    • 77956276464 scopus 로고    scopus 로고
    • tRNA biology charges to the front
    • [CrossRef] [PubMed]
    • Phizicky, E.M.; Hopper, A.K. tRNA biology charges to the front. Genes Dev. 2010, 24, 1832-1860. [CrossRef] [PubMed]
    • (2010) Genes Dev , vol.24 , pp. 1832-1860
    • Phizicky, E.M.1    Hopper, A.K.2
  • 17
    • 84869093362 scopus 로고    scopus 로고
    • Extensive degradation of RNA precursors by the exosome in wild-type cells
    • [CrossRef] [PubMed]
    • Gudipati, R.K.; Xu, Z.; Lebreton, A.; Seraphin, B.; Steinmetz, L.M.; Jacquier, A.; Libri, D. Extensive degradation of RNA precursors by the exosome in wild-type cells. Mol. Cell 2012, 48, 409-421. [CrossRef] [PubMed]
    • (2012) Mol. Cell , vol.48 , pp. 409-421
    • Gudipati, R.K.1    Xu, Z.2    Lebreton, A.3    Seraphin, B.4    Steinmetz, L.M.5    Jacquier, A.6    Libri, D.7
  • 18
    • 0032428969 scopus 로고    scopus 로고
    • The essential Gcd10p-Gcd14p nuclear complex is required for 1-methyladenosine modification and maturation of initiator methionyl-tRNA
    • [CrossRef] [PubMed]
    • Anderson, J.; Phan, L.; Cuesta, R.; Carlson, B.A.; Pak, M.; Asano, K.; Bjork, G.R.; Tamame, M.; Hinnebusch, A.G. The essential Gcd10p-Gcd14p nuclear complex is required for 1-methyladenosine modification and maturation of initiator methionyl-tRNA. Genes Dev. 1998, 12, 3650-3662. [CrossRef] [PubMed]
    • (1998) Genes Dev , vol.12 , pp. 3650-3662
    • Anderson, J.1    Phan, L.2    Cuesta, R.3    Carlson, B.A.4    Pak, M.5    Asano, K.6    Bjork, G.R.7    Tamame, M.8    Hinnebusch, A.G.9
  • 19
    • 84910675377 scopus 로고    scopus 로고
    • tRNA modifications regulate translation during cellular stress
    • [CrossRef] [PubMed]
    • Gu, C.; Begley, T.J.; Dedon, P.C. tRNA modifications regulate translation during cellular stress. FEBS Lett. 2014, 588, 4287-4296. [CrossRef] [PubMed]
    • (2014) FEBS Lett , vol.588 , pp. 4287-4296
    • Gu, C.1    Begley, T.J.2    Dedon, P.C.3
  • 20
    • 0026059582 scopus 로고
    • In vivo pre-tRNA processing in Saccharomyces cerevisiae
    • [CrossRef] [PubMed]
    • O'Connor, J.P.; Peebles, C.L. In vivo pre-tRNA processing in Saccharomyces cerevisiae. Mol. Cell Biol. 1991, 11, 425-439. [CrossRef] [PubMed]
    • (1991) Mol. Cell Biol , vol.11 , pp. 425-439
    • O'connor, J.P.1    Peebles, C.L.2
  • 21
    • 0037439213 scopus 로고    scopus 로고
    • tRNA transfers to the limelight
    • [CrossRef] [PubMed]
    • Hopper, A.K.; Phizicky, E.M. tRNA transfers to the limelight. Genes Dev. 2003, 17, 162-180. [CrossRef] [PubMed]
    • (2003) Genes Dev , vol.17 , pp. 162-180
    • Hopper, A.K.1    Phizicky, E.M.2
  • 23
    • 78650444089 scopus 로고    scopus 로고
    • Archaeal/eukaryal RNase P: Subunits, functions and RNA diversification
    • [CrossRef] [PubMed]
    • Jarrous, N.; Gopalan, V. Archaeal/eukaryal RNase P: Subunits, functions and RNA diversification. Nucleic Acids Res. 2010, 38, 7885-7894. [CrossRef] [PubMed]
    • (2010) Nucleic Acids Res , vol.38 , pp. 7885-7894
    • Jarrous, N.1    Gopalan, V.2
  • 24
    • 84861141850 scopus 로고    scopus 로고
    • Prorp proteins support RNase P activity in both organelles and the nucleus in Arabidopsis
    • [CrossRef] [PubMed]
    • Gutmann, B.; Gobert, A.; Giege, P. Prorp proteins support RNase P activity in both organelles and the nucleus in Arabidopsis. Genes Dev. 2012, 26, 1022-1027. [CrossRef] [PubMed]
    • (2012) Genes Dev , vol.26 , pp. 1022-1027
    • Gutmann, B.1    Gobert, A.2    Giege, P.3
  • 26
    • 0021013526 scopus 로고
    • The RNA moiety of ribonuclease P is the catalytic subunit of the enzyme
    • [CrossRef]
    • Guerrier-Takada, C.; Gardiner, K.; Marsh, T.; Pace, N.; Altman, S. The RNA moiety of ribonuclease P is the catalytic subunit of the enzyme. Cell 1983, 35, 849-857. [CrossRef]
    • (1983) Cell , vol.35 , pp. 849-857
    • Guerrier-Takada, C.1    Gardiner, K.2    Marsh, T.3    Pace, N.4    Altman, S.5
  • 27
    • 25644433566 scopus 로고    scopus 로고
    • Crystal structure of the RNA component of bacterial ribonuclease p
    • [CrossRef] [PubMed]
    • Torres-Larios, A.; Swinger, K.K.; Krasilnikov, A.S.; Pan, T.; Mondragon, A. Crystal structure of the RNA component of bacterial ribonuclease p. Nature 2005, 437, 584-587. [CrossRef] [PubMed]
    • (2005) Nature , vol.437 , pp. 584-587
    • Torres-Larios, A.1    Swinger, K.K.2    Krasilnikov, A.S.3    Pan, T.4    Mondragon, A.5
  • 30
    • 33750489707 scopus 로고    scopus 로고
    • Structure and function of eukaryotic ribonuclease P RNA
    • [CrossRef] [PubMed]
    • Marquez, S.M.; Chen, J.L.; Evans, D.; Pace, N.R. Structure and function of eukaryotic ribonuclease P RNA. Mol. Cell 2006, 24, 445-456. [CrossRef] [PubMed]
    • (2006) Mol. Cell , vol.24 , pp. 445-456
    • Marquez, S.M.1    Chen, J.L.2    Evans, D.3    Pace, N.R.4
  • 31
  • 33
    • 0030576503 scopus 로고    scopus 로고
    • Maturation pathways for E. Coli tRNA precursors: A random multienzyme process in vivo
    • [CrossRef]
    • Li, Z.; Deutscher, M.P. Maturation pathways for E. coli tRNA precursors: A random multienzyme process in vivo. Cell 1996, 86, 503-512. [CrossRef]
    • (1996) Cell , vol.86 , pp. 503-512
    • Li, Z.1    Deutscher, M.P.2
  • 34
    • 84890588127 scopus 로고    scopus 로고
    • tRNA 3' processing in yeast involves tRNAse Z, Rex1, and Rrp6
    • [CrossRef] [PubMed]
    • Skowronek, E.; Grzechnik, P.; Spath, B.; Marchfelder, A.; Kufel, J. tRNA 3' processing in yeast involves tRNAse Z, Rex1, and Rrp6. RNA 2014, 20, 115-130. [CrossRef] [PubMed]
    • (2014) RNA , vol.20 , pp. 115-130
    • Skowronek, E.1    Grzechnik, P.2    Spath, B.3    Marchfelder, A.4    Kufel, J.5
  • 35
    • 44149101017 scopus 로고    scopus 로고
    • Competition between the Rex1 exonuclease and the La protein affects both Trf4p-mediated RNA quality control and pre-tRNA maturation
    • [CrossRef] [PubMed]
    • Copela, L.A.; Fernandez, C.F.; Sherrer, R.L.; Wolin, S.L. Competition between the Rex1 exonuclease and the La protein affects both Trf4p-mediated RNA quality control and pre-tRNA maturation. RNA 2008, 14, 1214-1227. [CrossRef] [PubMed]
    • (2008) RNA , vol.14 , pp. 1214-1227
    • Copela, L.A.1    Fernandez, C.F.2    Sherrer, R.L.3    Wolin, S.L.4
  • 36
    • 58549100937 scopus 로고    scopus 로고
    • Rex1p deficiency leads to accumulation of precursor initiator tRNAmet and polyadenylation of substrate RNAs in Saccharomyces cerevisiae
    • [CrossRef] [PubMed]
    • Ozanick, S.G.; Wang, X.; Costanzo, M.; Brost, R.L.; Boone, C.; Anderson, J.T. Rex1p deficiency leads to accumulation of precursor initiator tRNAmet and polyadenylation of substrate RNAs in Saccharomyces cerevisiae. Nucleic Acids Res. 2009, 37, 298-308. [CrossRef] [PubMed]
    • (2009) Nucleic Acids Res , vol.37 , pp. 298-308
    • Ozanick, S.G.1    Wang, X.2    Costanzo, M.3    Brost, R.L.4    Boone, C.5    Anderson, J.T.6
  • 37
    • 0033777266 scopus 로고    scopus 로고
    • Function of the Ski4p (Csl4p) and Ski7p proteins in 3'-to-5' degradation of mRNA
    • [CrossRef] [PubMed]
    • Van Hoof, A.; Staples, R.R.; Baker, R.E.; Parker, R. Function of the Ski4p (Csl4p) and Ski7p proteins in 3'-to-5' degradation of mRNA. Mol. Cell Biol. 2000, 20, 8230-8243. [CrossRef] [PubMed]
    • (2000) Mol. Cell Biol , vol.20 , pp. 8230-8243
    • Van Hoof, A.1    Staples, R.R.2    Baker, R.E.3    Parker, R.4
  • 38
    • 26444483970 scopus 로고    scopus 로고
    • Characterization of Trz1, a yeast homolog of the human candidate prostate cancer susceptibility gene ELAC2 encoding tRNAse Z
    • [CrossRef] [PubMed]
    • Chen, Y.; Beck, A.; Davenport, C.; Shattuck, D.; Tavtigian, S.V. Characterization of Trz1, a yeast homolog of the human candidate prostate cancer susceptibility gene ELAC2 encoding tRNAse Z. BMC Mol. Biol. 2005, 6, 12. [CrossRef] [PubMed]
    • (2005) BMC Mol. Biol , vol.6 , pp. 12
    • Chen, Y.1    Beck, A.2    Davenport, C.3    Shattuck, D.4    Tavtigian, S.V.5
  • 39
    • 84857878816 scopus 로고    scopus 로고
    • RNase Z and the RNA degradosome are part of a stable supercomplex
    • [CrossRef] [PubMed]
    • Daoud, R.; Forget, L.; Lang, B.F. Yeast mitochondrial RNase P, RNase Z and the RNA degradosome are part of a stable supercomplex. Nucleic Acids Res. 2012, 40, 1728-1736. [CrossRef] [PubMed]
    • (2012) Nucleic Acids Res , vol.40 , pp. 1728-1736
    • Daoud, R.1    Forget, L.2    Lang, B.F.3    Yeast Mitochondrial Rnase, P.4
  • 40
    • 80052272097 scopus 로고    scopus 로고
    • 3' processing of eukaryotic precursor tRNAs
    • [CrossRef] [PubMed]
    • Maraia, R.J.; Lamichhane, T.N. 3' processing of eukaryotic precursor tRNAs. Wiley Interdiscip. Rev. RNA 2011, 2, 362-375. [CrossRef] [PubMed]
    • (2011) Wiley Interdiscip. Rev. RNA , vol.2 , pp. 362-375
    • Maraia, R.J.1    Lamichhane, T.N.2
  • 41
    • 0028891242 scopus 로고
    • A yeast RNA binding protein that resembles the human autoantigen La
    • [CrossRef] [PubMed]
    • Lin-Marq, N.; Clarkson, S.G. A yeast RNA binding protein that resembles the human autoantigen La. J. Mol. Biol. 1995, 245, 81-85. [CrossRef] [PubMed]
    • (1995) J. Mol. Biol , vol.245 , pp. 81-85
    • Lin-Marq, N.1    Clarkson, S.G.2
  • 42
    • 0021305722 scopus 로고
    • Purified lupus antigen La recognizes an oligouridylate stretch common to the 3' termini of RNA polymerase iii transcripts
    • [CrossRef]
    • Stefano, J.E. Purified lupus antigen La recognizes an oligouridylate stretch common to the 3' termini of RNA polymerase iii transcripts. Cell 1984, 36, 145-154. [CrossRef]
    • (1984) Cell , vol.36 , pp. 145-154
    • Stefano, J.E.1
  • 43
    • 0030904723 scopus 로고    scopus 로고
    • The yeast La protein is required for the 3' endonucleolytic cleavage that matures tRNA precursors
    • [CrossRef]
    • Yoo, C.J.; Wolin, S.L. The yeast La protein is required for the 3' endonucleolytic cleavage that matures tRNA precursors. Cell 1997, 89, 393-402. [CrossRef]
    • (1997) Cell , vol.89 , pp. 393-402
    • Yoo, C.J.1    Wolin, S.L.2
  • 44
    • 0347747969 scopus 로고    scopus 로고
    • A La protein requirement for efficient pre-tRNA folding
    • [CrossRef] [PubMed]
    • Chakshusmathi, G.; Kim, S.D.; Rubinson, D.A.; Wolin, S.L. A La protein requirement for efficient pre-tRNA folding. EMBO J. 2003, 22, 6562-6572. [CrossRef] [PubMed]
    • (2003) EMBO J , vol.22 , pp. 6562-6572
    • Chakshusmathi, G.1    Kim, S.D.2    Rubinson, D.A.3    Wolin, S.L.4
  • 45
    • 0031469506 scopus 로고    scopus 로고
    • The La protein in schizosaccharomyces pombe: A conserved yet dispensable phosphoprotein that functions in tRNA maturation
    • [PubMed]
    • Van Horn, D.J.; Yoo, C.J.; Xue, D.; Shi, H.; Wolin, S.L. The La protein in schizosaccharomyces pombe: A conserved yet dispensable phosphoprotein that functions in tRNA maturation. RNA 1997, 3, 1434-1443. [PubMed]
    • (1997) RNA , vol.3 , pp. 1434-1443
    • Van Horn, D.J.1    Yoo, C.J.2    Xue, D.3    Shi, H.4    Wolin, S.L.5
  • 46
    • 84958691767 scopus 로고    scopus 로고
    • Control of Saccharomyces cerevisiae pre-tRNA processing by environmental conditions
    • [CrossRef] [PubMed]
    • Foretek, D.; Wu, J.; Hopper, A.K.; Boguta, M. Control of Saccharomyces cerevisiae pre-tRNA processing by environmental conditions. RNA 2016, 22, 339-349. [CrossRef] [PubMed]
    • (2016) RNA , vol.22 , pp. 339-349
    • Foretek, D.1    Wu, J.2    Hopper, A.K.3    Boguta, M.4
  • 47
    • 84944680246 scopus 로고    scopus 로고
    • Codon-biased translation can be regulated by wobble-base tRNA modification systems during cellular stress responses
    • [CrossRef] [PubMed]
    • Endres, L.; Dedon, P.C.; Begley, T.J. Codon-biased translation can be regulated by wobble-base tRNA modification systems during cellular stress responses. RNA Biol. 2015, 12, 603-614. [CrossRef] [PubMed]
    • (2015) RNA Biol , vol.12 , pp. 603-614
    • Endres, L.1    Dedon, P.C.2    Begley, T.J.3
  • 49
    • 0345276475 scopus 로고    scopus 로고
    • Differential phosphorylation and subcellular localization of La RNPs associated with precursor tRNAs and translation-related mRNAs
    • [CrossRef]
    • Intine, R.V.; Tenenbaum, S.A.; Sakulich, A.L.; Keene, J.D.; Maraia, R.J. Differential phosphorylation and subcellular localization of La RNPs associated with precursor tRNAs and translation-related mRNAs. Mol. Cell 2003, 12, 1301-1307. [CrossRef]
    • (2003) Mol. Cell , vol.12 , pp. 1301-1307
    • Intine, R.V.1    Tenenbaum, S.A.2    Sakulich, A.L.3    Keene, J.D.4    Maraia, R.J.5
  • 50
    • 0032729827 scopus 로고    scopus 로고
    • The La (SS-B) autoantigen, a key protein in RNA biogenesis, is dephosphorylated and cleaved early during apoptosis
    • [CrossRef] [PubMed]
    • Rutjes, S.A.; Utz, P.J.; van der Heijden, A.; Broekhuis, C.; van Venrooij, W.J.; Pruijn, G.J. The La (SS-B) autoantigen, a key protein in RNA biogenesis, is dephosphorylated and cleaved early during apoptosis. Cell Death Differ. 1999, 6, 976-986. [CrossRef] [PubMed]
    • (1999) Cell Death Differ , vol.6 , pp. 976-986
    • Rutjes, S.A.1    Utz, P.J.2    Van Der Heijden, A.3    Broekhuis, C.4    Van Venrooij, W.J.5    Pruijn, G.J.6
  • 51
    • 0027288847 scopus 로고
    • Substitution of the 3' terminal adenosine residue of transfer RNA in vivo
    • [CrossRef] [PubMed]
    • Reuven, N.B.; Deutscher, M.P. Substitution of the 3' terminal adenosine residue of transfer RNA in vivo. Proc. Natl. Acad. Sci. USA 1993, 90, 4350-4353. [CrossRef] [PubMed]
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 4350-4353
    • Reuven, N.B.1    Deutscher, M.P.2
  • 52
    • 0023394389 scopus 로고
    • tRNA nucleotidyltransferase is not essential for Escherichia coli viability
    • [PubMed]
    • Zhu, L.; Deutscher, M.P. tRNA nucleotidyltransferase is not essential for Escherichia coli viability. EMBO J. 1987, 6, 2473-2477. [PubMed]
    • (1987) EMBO J , vol.6 , pp. 2473-2477
    • Zhu, L.1    Deutscher, M.P.2
  • 53
    • 0025130559 scopus 로고
    • Isolation of a temperature-sensitive mutant with an altered tRNA nucleotidyltransferase and cloning of the gene encoding tRNA nucleotidyltransferase in the yeast Saccharomyces cerevisiae
    • [PubMed]
    • Aebi, M.; Kirchner, G.; Chen, J.Y.; Vijayraghavan, U.; Jacobson, A.; Martin, N.C.; Abelson, J. Isolation of a temperature-sensitive mutant with an altered tRNA nucleotidyltransferase and cloning of the gene encoding tRNA nucleotidyltransferase in the yeast Saccharomyces cerevisiae. J. Biol. Chem. 1990, 265, 16216-16220. [PubMed]
    • (1990) J. Biol. Chem , vol.265 , pp. 16216-16220
    • Aebi, M.1    Kirchner, G.2    Chen, J.Y.3    Vijayraghavan, U.4    Jacobson, A.5    Martin, N.C.6    Abelson, J.7
  • 54
    • 0028657592 scopus 로고
    • How single genes provide tRNA processing enzymes to mitochondria, nuclei and the cytosol
    • [CrossRef]
    • Martin, N.C.; Hopper, A.K. How single genes provide tRNA processing enzymes to mitochondria, nuclei and the cytosol. Biochimie 1994, 76, 1161-1167. [CrossRef]
    • (1994) Biochimie , vol.76 , pp. 1161-1167
    • Martin, N.C.1    Hopper, A.K.2
  • 55
    • 84884638166 scopus 로고    scopus 로고
    • Reversible and rapid transfer-RNA deactivation as a mechanism of translational repression in stress
    • [CrossRef] [PubMed]
    • Czech, A.; Wende, S.; Morl, M.; Pan, T.; Ignatova, Z. Reversible and rapid transfer-RNA deactivation as a mechanism of translational repression in stress. PLoS Genet. 2013, 9, e1003767. [CrossRef] [PubMed]
    • (2013) Plos Genet , vol.9
    • Czech, A.1    Wende, S.2    Morl, M.3    Pan, T.4    Ignatova, Z.5
  • 56
    • 84922688087 scopus 로고    scopus 로고
    • On-enzyme refolding permits small RNA and tRNA surveillance by the CCA-adding enzyme
    • [CrossRef] [PubMed]
    • Kuhn, C.D.; Wilusz, J.E.; Zheng, Y.; Beal, P.A.; Joshua-Tor, L. On-enzyme refolding permits small RNA and tRNA surveillance by the CCA-adding enzyme. Cell 2015, 160, 644-658. [CrossRef] [PubMed]
    • (2015) Cell , vol.160 , pp. 644-658
    • Kuhn, C.D.1    Wilusz, J.E.2    Zheng, Y.3    Beal, P.A.4    Joshua-Tor, L.5
  • 57
    • 81055122667 scopus 로고    scopus 로고
    • tRNAs marked with CCACCA are targeted for degradation
    • [CrossRef] [PubMed]
    • Wilusz, J.E.; Whipple, J.M.; Phizicky, E.M.; Sharp, P.A. tRNAs marked with CCACCA are targeted for degradation. Science 2011, 334, 817-821. [CrossRef] [PubMed]
    • (2011) Science , vol.334 , pp. 817-821
    • Wilusz, J.E.1    Whipple, J.M.2    Phizicky, E.M.3    Sharp, P.A.4
  • 59
    • 84871436566 scopus 로고    scopus 로고
    • Modifications: Nature's combinatorial chemistry playground. Wiley Interdiscip
    • [CrossRef] [PubMed]
    • Jackman, J.E.; Alfonzo, J.D. Transfer RNA modifications: Nature's combinatorial chemistry playground. Wiley Interdiscip. Rev. RNA 2013, 4, 35-48. [CrossRef] [PubMed]
    • (2013) Rev. RNA , vol.4 , pp. 35-48
    • Jackman, J.E.1    Alfonzo, J.D.2    Transfer, R.3
  • 60
    • 84870152928 scopus 로고    scopus 로고
    • Biosynthesis and function of posttranscriptional modifications of transfer RNAs
    • [CrossRef] [PubMed]
    • El Yacoubi, B.; Bailly, M.; de Crecy-Lagard, V. Biosynthesis and function of posttranscriptional modifications of transfer RNAs. Annu. Rev. Genet. 2012, 46, 69-95. [CrossRef] [PubMed]
    • (2012) Annu. Rev. Genet , vol.46 , pp. 69-95
    • El Yacoubi, B.1    Bailly, M.2    de Crecy-Lagard, V.3
  • 61
    • 0033527628 scopus 로고    scopus 로고
    • An adenosine deaminase that generates inosine at the wobble position of tRNAs
    • [CrossRef] [PubMed]
    • Gerber, A.P.; Keller, W. An adenosine deaminase that generates inosine at the wobble position of tRNAs. Science 1999, 286, 1146-1149. [CrossRef] [PubMed]
    • (1999) Science , vol.286 , pp. 1146-1149
    • Gerber, A.P.1    Keller, W.2
  • 62
    • 34548816729 scopus 로고    scopus 로고
    • Role of a tRNA base modification and its precursors in frameshifting in eukaryotes
    • [CrossRef] [PubMed]
    • Waas, W.F.; Druzina, Z.; Hanan, M.; Schimmel, P. Role of a tRNA base modification and its precursors in frameshifting in eukaryotes. J. Biol. Chem. 2007, 282, 26026-26034. [CrossRef] [PubMed]
    • (2007) J. Biol. Chem , vol.282 , pp. 26026-26034
    • Waas, W.F.1    Druzina, Z.2    Hanan, M.3    Schimmel, P.4
  • 64
    • 55549137731 scopus 로고    scopus 로고
    • Thio-modification of yeast cytosolic tRNA requires a ubiquitin-related system that resembles bacterial sulfur transfer systems
    • [CrossRef] [PubMed]
    • Nakai, Y.; Nakai, M.; Hayashi, H. Thio-modification of yeast cytosolic tRNA requires a ubiquitin-related system that resembles bacterial sulfur transfer systems. J. Biol. Chem. 2008, 283, 27469-27476. [CrossRef] [PubMed]
    • (2008) J. Biol. Chem , vol.283 , pp. 27469-27476
    • Nakai, Y.1    Nakai, M.2    Hayashi, H.3
  • 65
    • 57449121400 scopus 로고    scopus 로고
    • A functional proteomics approach links the ubiquitin-related modifier Urm1 to a tRNA modification pathway
    • [CrossRef] [PubMed]
    • Schlieker, C.D.; Van der Veen, A.G.; Damon, J.R.; Spooner, E.; Ploegh, H.L. A functional proteomics approach links the ubiquitin-related modifier Urm1 to a tRNA modification pathway. Proc. Natl. Acad. Sci. USA 2008, 105, 18255-18260. [CrossRef] [PubMed]
    • (2008) Proc. Natl. Acad. Sci. USA , vol.105 , pp. 18255-18260
    • Schlieker, C.D.1    Van Der Veen, A.G.2    Damon, J.R.3    Spooner, E.4    Ploegh, H.L.5
  • 66
    • 84931576485 scopus 로고    scopus 로고
    • Optimization of codon translation rates via tRNA modifications maintains proteome integrity
    • [CrossRef] [PubMed]
    • Nedialkova, D.D.; Leidel, S.A. Optimization of codon translation rates via tRNA modifications maintains proteome integrity. Cell 2015, 161, 1606-1618. [CrossRef] [PubMed]
    • (2015) Cell , vol.161 , pp. 1606-1618
    • Nedialkova, D.D.1    Leidel, S.A.2
  • 67
    • 84953302322 scopus 로고    scopus 로고
    • Trm9-catalyzed tRNA modifications regulate global protein expression by codon-biased translation
    • [CrossRef] [PubMed]
    • Deng, W.; Babu, I.R.; Su, D.; Yin, S.; Begley, T.J.; Dedon, P.C. Trm9-catalyzed tRNA modifications regulate global protein expression by codon-biased translation. PLoS Genet. 2015, 11, e1005706. [CrossRef] [PubMed]
    • (2015) Plos Genet , vol.11
    • Deng, W.1    Babu, I.R.2    Su, D.3    Yin, S.4    Begley, T.J.5    Dedon, P.C.6
  • 68
    • 0036226647 scopus 로고    scopus 로고
    • Dual function of the tRNA(M(5)U54)methyltransferase in tRNA maturation
    • [CrossRef] [PubMed]
    • Johansson, M.J.; Bystrom, A.S. Dual function of the tRNA(m(5)U54)methyltransferase in tRNA maturation. RNA 2002, 8, 324-335. [CrossRef] [PubMed]
    • (2002) RNA , vol.8 , pp. 324-335
    • Johansson, M.J.1    Bystrom, A.S.2
  • 69
    • 44149119097 scopus 로고    scopus 로고
    • Degradation of several hypomodified mature tRNA species in Saccharomyces cerevisiae is mediated by Met22 and the 5'-3' exonucleases Rat1 and Xrn1
    • [CrossRef] [PubMed]
    • Chernyakov, I.; Whipple, J.M.; Kotelawala, L.; Grayhack, E.J.; Phizicky, E.M. Degradation of several hypomodified mature tRNA species in Saccharomyces cerevisiae is mediated by Met22 and the 5'-3' exonucleases Rat1 and Xrn1. Genes Dev. 2008, 22, 1369-1380. [CrossRef] [PubMed]
    • (2008) Genes Dev , vol.22 , pp. 1369-1380
    • Chernyakov, I.1    Whipple, J.M.2    Kotelawala, L.3    Grayhack, E.J.4    Phizicky, E.M.5
  • 70
    • 38049091553 scopus 로고    scopus 로고
    • Identification of yeast tRNA Um(44) 2'-O-methyltransferase (Trm44) and demonstration of a Trm44 role in sustaining levels of specific tRNA(Ser) species
    • [CrossRef] [PubMed]
    • Kotelawala, L.; Grayhack, E.J.; Phizicky, E.M. Identification of yeast tRNA Um(44) 2'-O-methyltransferase (Trm44) and demonstration of a Trm44 role in sustaining levels of specific tRNA(Ser) species. RNA 2008, 14, 158-169. [CrossRef] [PubMed]
    • (2008) RNA , vol.14 , pp. 158-169
    • Kotelawala, L.1    Grayhack, E.J.2    Phizicky, E.M.3
  • 71
    • 0035824521 scopus 로고    scopus 로고
    • Pus1p-dependent tRNA pseudouridinylation becomes essential when tRNA biogenesis is compromised in yeast
    • [CrossRef] [PubMed]
    • Grosshans, H.; Lecointe, F.; Grosjean, H.; Hurt, E.; Simos, G. Pus1p-dependent tRNA pseudouridinylation becomes essential when tRNA biogenesis is compromised in yeast. J. Biol. Chem. 2001, 276, 46333-46339. [CrossRef] [PubMed]
    • (2001) J. Biol. Chem , vol.276 , pp. 46333-46339
    • Grosshans, H.1    Lecointe, F.2    Grosjean, H.3    Hurt, E.4    Simos, G.5
  • 73
    • 84866622511 scopus 로고    scopus 로고
    • The yeast rapid tRNA decay pathway competes with elongation factor 1a for substrate tRNAs and acts on tRNAs lacking one or more of several modifications
    • [CrossRef] [PubMed]
    • Dewe, J.M.; Whipple, J.M.; Chernyakov, I.; Jaramillo, L.N.; Phizicky, E.M. The yeast rapid tRNA decay pathway competes with elongation factor 1a for substrate tRNAs and acts on tRNAs lacking one or more of several modifications. RNA 2012, 18, 1886-1896. [CrossRef] [PubMed]
    • (2012) RNA , vol.18 , pp. 1886-1896
    • Dewe, J.M.1    Whipple, J.M.2    Chernyakov, I.3    Jaramillo, L.N.4    Phizicky, E.M.5
  • 74
    • 80555131009 scopus 로고    scopus 로고
    • Initiation factor eIF2gamma promotes eIF2-GTP-Met-tRNAi(Met) ternary complex binding to the 40s ribosome
    • [CrossRef] [PubMed]
    • Shin, B.S.; Kim, J.R.; Walker, S.E.; Dong, J.; Lorsch, J.R.; Dever, T.E. Initiation factor eIF2gamma promotes eIF2-GTP-Met-tRNAi(Met) ternary complex binding to the 40s ribosome. Nat. Struct. Mol. Biol. 2011, 18, 1227-1234. [CrossRef] [PubMed]
    • (2011) Nat. Struct. Mol. Biol , vol.18 , pp. 1227-1234
    • Shin, B.S.1    Kim, J.R.2    Walker, S.E.3    Dong, J.4    Lorsch, J.R.5    Dever, T.E.6
  • 75
    • 84921374170 scopus 로고    scopus 로고
    • Functional importance of Psi38 and Psi39 in distinct tRNAs, amplified for tRNAGln(UUG) by unexpected temperature sensitivity of the s2U modification in yeast
    • [CrossRef] [PubMed]
    • Han, L.; Kon, Y.; Phizicky, E.M. Functional importance of Psi38 and Psi39 in distinct tRNAs, amplified for tRNAGln(UUG) by unexpected temperature sensitivity of the s2U modification in yeast. RNA 2015, 21, 188-201. [CrossRef] [PubMed]
    • (2015) RNA , vol.21 , pp. 188-201
    • Han, L.1    Kon, Y.2    Phizicky, E.M.3
  • 76
    • 84872584130 scopus 로고    scopus 로고
    • tRNAHis 5-methylcytidine levels increase in response to several growth arrest conditions in Saccharomyces cerevisiae
    • [CrossRef] [PubMed]
    • Preston, M.A.; D'Silva, S.; Kon, Y.; Phizicky, E.M. tRNAHis 5-methylcytidine levels increase in response to several growth arrest conditions in Saccharomyces cerevisiae. RNA 2013, 19, 243-256. [CrossRef] [PubMed]
    • (2013) RNA , vol.19 , pp. 243-256
    • Preston, M.A.1    D'silva, S.2    Kon, Y.3    Phizicky, E.M.4
  • 77
    • 84921365621 scopus 로고    scopus 로고
    • An evolutionary approach uncovers a diverse response of tRNA 2-thiolation to elevated temperatures in yeast
    • [CrossRef] [PubMed]
    • Alings, F.; Sarin, L.P.; Fufezan, C.; Drexler, H.C.; Leidel, S.A. An evolutionary approach uncovers a diverse response of tRNA 2-thiolation to elevated temperatures in yeast. RNA 2015, 21, 202-212. [CrossRef] [PubMed]
    • (2015) RNA , vol.21 , pp. 202-212
    • Alings, F.1    Sarin, L.P.2    Fufezan, C.3    Drexler, H.C.4    Leidel, S.A.5
  • 78
    • 84920999617 scopus 로고    scopus 로고
    • tRNA thiolation links translation to stress responses in Saccharomyces cerevisiae. Mol. Biol
    • [CrossRef] [PubMed]
    • Damon, J.R.; Pincus, D.; Ploegh, H.L. tRNA thiolation links translation to stress responses in Saccharomyces cerevisiae. Mol. Biol. Cell 2015, 26, 270-282. [CrossRef] [PubMed]
    • (2015) Cell , vol.26 , pp. 270-282
    • Damon, J.R.1    Pincus, D.2    Ploegh, H.L.3
  • 79
    • 78650683942 scopus 로고    scopus 로고
    • A quantitative systems approach reveals dynamic control of tRNA modifications during cellular stress
    • [CrossRef] [PubMed]
    • Chan, C.T.; Dyavaiah, M.; DeMott, M.S.; Taghizadeh, K.; Dedon, P.C.; Begley, T.J. A quantitative systems approach reveals dynamic control of tRNA modifications during cellular stress. PLoS Genet. 2010, 6, e1001247. [CrossRef] [PubMed]
    • (2010) Plos Genet , vol.6
    • Chan, C.T.1    Dyavaiah, M.2    Demott, M.S.3    Taghizadeh, K.4    Dedon, P.C.5    Begley, T.J.6
  • 80
    • 84922180958 scopus 로고    scopus 로고
    • Pseudouridine profiling reveals regulated mRNA pseudouridylation in yeast and human cells
    • [CrossRef] [PubMed]
    • Carlile, T.M.; Rojas-Duran, M.F.; Zinshteyn, B.; Shin, H.; Bartoli, K.M.; Gilbert, W.V. Pseudouridine profiling reveals regulated mRNA pseudouridylation in yeast and human cells. Nature 2014, 515, 143-146. [CrossRef] [PubMed]
    • (2014) Nature , vol.515 , pp. 143-146
    • Carlile, T.M.1    Rojas-Duran, M.F.2    Zinshteyn, B.3    Shin, H.4    Bartoli, K.M.5    Gilbert, W.V.6
  • 82
    • 84864828979 scopus 로고    scopus 로고
    • Reprogramming of tRNA modifications controls the oxidative stress response by codon-biased translation of proteins
    • [CrossRef] [PubMed]
    • Chan, C.T.; Pang, Y.L.; Deng, W.; Babu, I.R.; Dyavaiah, M.; Begley, T.J.; Dedon, P.C. Reprogramming of tRNA modifications controls the oxidative stress response by codon-biased translation of proteins. Nat. Commun. 2012, 3, 937. [CrossRef] [PubMed]
    • (2012) Nat. Commun , vol.3 , pp. 937
    • Chan, C.T.1    Pang, Y.L.2    Deng, W.3    Babu, I.R.4    Dyavaiah, M.5    Begley, T.J.6    Dedon, P.C.7
  • 83
    • 84896342480 scopus 로고    scopus 로고
    • A system of RNA modifications and biased codon use controls cellular stress response at the level of translation
    • [CrossRef] [PubMed]
    • Dedon, P.C.; Begley, T.J. A system of RNA modifications and biased codon use controls cellular stress response at the level of translation. Chem. Res. Toxicol. 2014, 27, 330-337. [CrossRef] [PubMed]
    • (2014) Chem. Res. Toxicol , vol.27 , pp. 330-337
    • Dedon, P.C.1    Begley, T.J.2
  • 84
    • 84929408617 scopus 로고    scopus 로고
    • Highly predictive reprogramming of tRNA modifications is linked to selective expression of codon-biased genes
    • [CrossRef] [PubMed]
    • Chan, C.T.; Deng, W.; Li, F.; DeMott, M.S.; Babu, I.R.; Begley, T.J.; Dedon, P.C. Highly predictive reprogramming of tRNA modifications is linked to selective expression of codon-biased genes. Chem. Res. Toxicol. 2015, 28, 978-988. [CrossRef] [PubMed]
    • (2015) Chem. Res. Toxicol , vol.28 , pp. 978-988
    • Chan, C.T.1    Deng, W.2    Li, F.3    Demott, M.S.4    Babu, I.R.5    Begley, T.J.6    Dedon, P.C.7
  • 85
    • 77955884641 scopus 로고    scopus 로고
    • RNA methylation by Dnmt2 protects transfer RNAs against stress-induced cleavage
    • [CrossRef] [PubMed]
    • Schaefer, M.; Pollex, T.; Hanna, K.; Tuorto, F.; Meusburger, M.; Helm, M.; Lyko, F. RNA methylation by Dnmt2 protects transfer RNAs against stress-induced cleavage. Genes Dev. 2010, 24, 1590-1595. [CrossRef] [PubMed]
    • (2010) Genes Dev , vol.24 , pp. 1590-1595
    • Schaefer, M.1    Pollex, T.2    Hanna, K.3    Tuorto, F.4    Meusburger, M.5    Helm, M.6    Lyko, F.7
  • 86
    • 52949102950 scopus 로고    scopus 로고
    • A genome-wide screen identifies genes required for formation of the wobble nucleoside 5-methoxycarbonylmethyl-2-thiouridine in Saccharomyces cerevisiae
    • [CrossRef] [PubMed]
    • Huang, B.; Lu, J.; Bystrom, A.S. A genome-wide screen identifies genes required for formation of the wobble nucleoside 5-methoxycarbonylmethyl-2-thiouridine in Saccharomyces cerevisiae. RNA 2008, 14, 2183-2194. [CrossRef] [PubMed]
    • (2008) RNA , vol.14 , pp. 2183-2194
    • Huang, B.1    Lu, J.2    Bystrom, A.S.3
  • 87
    • 39949083202 scopus 로고    scopus 로고
    • A decade of surprises for tRNA nuclear-cytoplasmic dynamics
    • [CrossRef] [PubMed]
    • Hopper, A.K.; Shaheen, H.H. A decade of surprises for tRNA nuclear-cytoplasmic dynamics. Trends Cell Biol. 2008, 18, 98-104. [CrossRef] [PubMed]
    • (2008) Trends Cell Biol , vol.18 , pp. 98-104
    • Hopper, A.K.1    Shaheen, H.H.2
  • 88
    • 34547407396 scopus 로고    scopus 로고
    • Retrograde nuclear accumulation of cytoplasmic tRNA in rat hepatoma cells in response to amino acid deprivation
    • [CrossRef] [PubMed]
    • Shaheen, H.H.; Horetsky, R.L.; Kimball, S.R.; Murthi, A.; Jefferson, L.S.; Hopper, A.K. Retrograde nuclear accumulation of cytoplasmic tRNA in rat hepatoma cells in response to amino acid deprivation. Proc. Natl. Acad. Sci. USA 2007, 104, 8845-8850. [CrossRef] [PubMed]
    • (2007) Proc. Natl. Acad. Sci. USA , vol.104 , pp. 8845-8850
    • Shaheen, H.H.1    Horetsky, R.L.2    Kimball, S.R.3    Murthi, A.4    Jefferson, L.S.5    Hopper, A.K.6
  • 89
    • 79960582843 scopus 로고    scopus 로고
    • Retrograde nuclear import of tRNA precursors is required for modified base biogenesis in yeast
    • [CrossRef] [PubMed]
    • Ohira, T.; Suzuki, T. Retrograde nuclear import of tRNA precursors is required for modified base biogenesis in yeast. Proc. Natl. Acad. Sci. USA 2011, 108, 10502-10507. [CrossRef] [PubMed]
    • (2011) Proc. Natl. Acad. Sci. USA , vol.108 , pp. 10502-10507
    • Ohira, T.1    Suzuki, T.2
  • 90
    • 33750241652 scopus 로고    scopus 로고
    • tRNAs promote nuclear import of HIV-1 intracellular reverse transcription complexes
    • [CrossRef] [PubMed]
    • Zaitseva, L.; Myers, R.; Fassati, A. tRNAs promote nuclear import of HIV-1 intracellular reverse transcription complexes. PLoS Biol. 2006, 4, e332. [CrossRef] [PubMed]
    • (2006) Plos Biol , vol.4
    • Zaitseva, L.1    Myers, R.2    Fassati, A.3
  • 91
    • 84891368395 scopus 로고    scopus 로고
    • Retrograde transfer RNA nuclear import provides a new level of tRNA quality control in Saccharomyces cerevisiae
    • [CrossRef] [PubMed]
    • Kramer, E.B.; Hopper, A.K. Retrograde transfer RNA nuclear import provides a new level of tRNA quality control in Saccharomyces cerevisiae. Proc. Natl. Acad. Sci. USA 2013, 110, 21042-21047. [CrossRef] [PubMed]
    • (2013) Proc. Natl. Acad. Sci. USA , vol.110 , pp. 21042-21047
    • Kramer, E.B.1    Hopper, A.K.2
  • 92
    • 84926337845 scopus 로고    scopus 로고
    • Genome-wide investigation of the role of the tRNA nucleus-cytoplasm trafficking pathway in regulation of the yeast s. Cerevisiae transcriptome and proteome
    • Chu, H.Y.; Hopper, A.K. Genome-wide investigation of the role of the tRNA nucleus-cytoplasm trafficking pathway in regulation of the yeast s. Cerevisiae transcriptome and proteome. Mol. Cell Biol. 2013, 2013, 26.
    • (2013) Mol. Cell Biol , vol.2013 , pp. 26
    • Chu, H.Y.1    Hopper, A.K.2
  • 93
    • 0032510462 scopus 로고    scopus 로고
    • Identification of a nuclear export receptor for tRNA
    • [CrossRef]
    • Arts, G.J.; Fornerod, M.; Mattaj, I.W. Identification of a nuclear export receptor for tRNA. Curr. Biol. 1998, 8, 305-314. [CrossRef]
    • (1998) Curr. Biol , vol.8 , pp. 305-314
    • Arts, G.J.1    Fornerod, M.2    Mattaj, I.W.3
  • 95
    • 0041888473 scopus 로고    scopus 로고
    • PAUSED encodes the Arabidopsis exportin-t ortholog
    • [CrossRef] [PubMed]
    • Hunter, C.A.; Aukerman, M.J.; Sun, H.; Fokina, M.; Poethig, R.S. PAUSED encodes the Arabidopsis exportin-t ortholog. Plant Physiol. 2003, 132, 2135-2143. [CrossRef] [PubMed]
    • (2003) Plant Physiol , vol.132 , pp. 2135-2143
    • Hunter, C.A.1    Aukerman, M.J.2    Sun, H.3    Fokina, M.4    Poethig, R.S.5
  • 96
    • 69949094998 scopus 로고    scopus 로고
    • Structures of the tRNA export factor in the nuclear and cytosolic states
    • [CrossRef] [PubMed]
    • Cook, A.G.; Fukuhara, N.; Jinek, M.; Conti, E. Structures of the tRNA export factor in the nuclear and cytosolic states. Nature 2009, 461, 60-65. [CrossRef] [PubMed]
    • (2009) Nature , vol.461 , pp. 60-65
    • Cook, A.G.1    Fukuhara, N.2    Jinek, M.3    Conti, E.4
  • 97
    • 0031771756 scopus 로고    scopus 로고
    • Yeast Los1p has properties of an exportin-like nucleocytoplasmic transport factor for tRNA
    • [CrossRef] [PubMed]
    • Hellmuth, K.; Lau, D.M.; Bischoff, F.R.; Kunzler, M.; Hurt, E.; Simos, G. Yeast Los1p has properties of an exportin-like nucleocytoplasmic transport factor for tRNA. Mol. Cell Biol. 1998, 18, 6374-6386. [CrossRef] [PubMed]
    • (1998) Mol. Cell Biol , vol.18 , pp. 6374-6386
    • Hellmuth, K.1    Lau, D.M.2    Bischoff, F.R.3    Kunzler, M.4    Hurt, E.5    Simos, G.6
  • 98
    • 0018841174 scopus 로고
    • Processing of intervening sequences: A new yeast mutant which fails to excise intervening sequences from precursor tRNAs
    • [CrossRef]
    • Hopper, A.K.; Schultz, L.D.; Shapiro, R.A. Processing of intervening sequences: A new yeast mutant which fails to excise intervening sequences from precursor tRNAs. Cell 1980, 19, 741-751. [CrossRef]
    • (1980) Cell , vol.19 , pp. 741-751
    • Hopper, A.K.1    Schultz, L.D.2    Shapiro, R.A.3
  • 99
    • 0031739249 scopus 로고    scopus 로고
    • tRNA nuclear export in Saccharomyces cerevisiae: In situ hybridization analysis
    • [CrossRef] [PubMed]
    • Sarkar, S.; Hopper, A.K. tRNA nuclear export in Saccharomyces cerevisiae: In situ hybridization analysis. Mol. Biol. Cell 1998, 9, 3041-3055. [CrossRef] [PubMed]
    • (1998) Mol. Biol. Cell , vol.9 , pp. 3041-3055
    • Sarkar, S.1    Hopper, A.K.2
  • 100
    • 0032535450 scopus 로고    scopus 로고
    • The role of exportin-t in selective nuclear export of mature tRNAs
    • [CrossRef] [PubMed]
    • Arts, G.J.; Kuersten, S.; Romby, P.; Ehresmann, B.; Mattaj, I.W. The role of exportin-t in selective nuclear export of mature tRNAs. EMBO J. 1998, 17, 7430-7441. [CrossRef] [PubMed]
    • (1998) EMBO J , vol.17 , pp. 7430-7441
    • Arts, G.J.1    Kuersten, S.2    Romby, P.3    Ehresmann, B.4    Mattaj, I.W.5
  • 101
    • 0032509304 scopus 로고    scopus 로고
    • Proofreading and aminoacylation of tRNAs before export from the nucleus
    • [CrossRef] [PubMed]
    • Lund, E.; Dahlberg, J.E. Proofreading and aminoacylation of tRNAs before export from the nucleus. Science 1998, 282, 2082-2085. [CrossRef] [PubMed]
    • (1998) Science , vol.282 , pp. 2082-2085
    • Lund, E.1    Dahlberg, J.E.2
  • 103
    • 84926375059 scopus 로고    scopus 로고
    • In vivo biochemical analyses reveal distinct roles of beta-importins and eEF1a in tRNA subcellular traffic
    • [CrossRef] [PubMed]
    • Huang, H.Y.; Hopper, A.K. In vivo biochemical analyses reveal distinct roles of beta-importins and eEF1a in tRNA subcellular traffic. Genes Dev. 2015, 29, 772-783. [CrossRef] [PubMed]
    • (2015) Genes Dev , vol.29 , pp. 772-783
    • Huang, H.Y.1    Hopper, A.K.2
  • 104
    • 0041467844 scopus 로고    scopus 로고
    • Possibility of cytoplasmic pre-tRNA splicing: The yeast tRNA splicing endonuclease mainly localizes on the mitochondria. Mol. Biol
    • [CrossRef] [PubMed]
    • Yoshihisa, T.; Yunoki-Esaki, K.; Ohshima, C.; Tanaka, N.; Endo, T. Possibility of cytoplasmic pre-tRNA splicing: The yeast tRNA splicing endonuclease mainly localizes on the mitochondria. Mol. Biol. Cell 2003, 14, 3266-3279. [CrossRef] [PubMed]
    • (2003) Cell , vol.14 , pp. 3266-3279
    • Yoshihisa, T.1    Yunoki-Esaki, K.2    Ohshima, C.3    Tanaka, N.4    Endo, T.5
  • 105
    • 76649140836 scopus 로고    scopus 로고
    • Regulation of tRNA bidirectional nuclear-cytoplasmic trafficking in Saccharomyces cerevisiae
    • [CrossRef] [PubMed]
    • Murthi, A.; Shaheen, H.H.; Huang, H.Y.; Preston, M.A.; Lai, T.P.; Phizicky, E.M.; Hopper, A.K. Regulation of tRNA bidirectional nuclear-cytoplasmic trafficking in Saccharomyces cerevisiae. Mol. Biol. Cell 2010, 21, 639-649. [CrossRef] [PubMed]
    • (2010) Mol. Biol. Cell , vol.21 , pp. 639-649
    • Murthi, A.1    Shaheen, H.H.2    Huang, H.Y.3    Preston, M.A.4    Lai, T.P.5    Phizicky, E.M.6    Hopper, A.K.7
  • 106
    • 21744453148 scopus 로고    scopus 로고
    • tRNA actively shuttles between the nucleus and cytosol in yeast
    • [CrossRef] [PubMed]
    • Takano, A.; Endo, T.; Yoshihisa, T. tRNA actively shuttles between the nucleus and cytosol in yeast. Science 2005, 309, 140-142. [CrossRef] [PubMed]
    • (2005) Science , vol.309 , pp. 140-142
    • Takano, A.1    Endo, T.2    Yoshihisa, T.3
  • 107
    • 84949957312 scopus 로고    scopus 로고
    • Genome-wide screen uncovers novel pathways for tRNA processing and nuclear-cytoplasmic dynamics
    • [PubMed]
    • Wu, J.; Bao, A.; Chatterjee, K.; Wan, Y.; Hopper, A.K. Genome-wide screen uncovers novel pathways for tRNA processing and nuclear-cytoplasmic dynamics. Genes Dev. 2015, 29, 2633-2644. [PubMed]
    • (2015) Genes Dev , vol.29 , pp. 2633-2644
    • Wu, J.1    Bao, A.2    Chatterjee, K.3    Wan, Y.4    Hopper, A.K.5
  • 108
    • 23844508130 scopus 로고    scopus 로고
    • Retrograde movement of tRNAs from the cytoplasm to the nucleus in Saccharomyces cerevisiae
    • [CrossRef] [PubMed]
    • Shaheen, H.H.; Hopper, A.K. Retrograde movement of tRNAs from the cytoplasm to the nucleus in Saccharomyces cerevisiae. Proc. Natl. Acad. Sci. USA 2005, 102, 11290-11295. [CrossRef] [PubMed]
    • (2005) Proc. Natl. Acad. Sci. USA , vol.102 , pp. 11290-11295
    • Shaheen, H.H.1    Hopper, A.K.2
  • 109
    • 84926435571 scopus 로고    scopus 로고
    • Cytosolic Hsp70 and co-chaperones constitute a novel system for tRNA import into the nucleus
    • [CrossRef] [PubMed]
    • Takano, A.; Kajita, T.; Mochizuki, M.; Endo, T.; Yoshihisa, T. Cytosolic Hsp70 and co-chaperones constitute a novel system for tRNA import into the nucleus. eLife 2015, 4. [CrossRef] [PubMed]
    • (2015) Elife , pp. 4
    • Takano, A.1    Kajita, T.2    Mochizuki, M.3    Endo, T.4    Yoshihisa, T.5
  • 110
    • 0034175551 scopus 로고    scopus 로고
    • An aminoacylation-dependent nuclear tRNA export pathway in yeast
    • [PubMed]
    • Grosshans, H.; Hurt, E.; Simos, G. An aminoacylation-dependent nuclear tRNA export pathway in yeast. Genes Dev. 2000, 14, 830-840. [PubMed]
    • (2000) Genes Dev , vol.14 , pp. 830-840
    • Grosshans, H.1    Hurt, E.2    Simos, G.3
  • 111
    • 34250711447 scopus 로고    scopus 로고
    • Inorganic phosphate deprivation causes tRNA nuclear accumulation via retrograde transport in Saccharomyces cerevisiae
    • [CrossRef] [PubMed]
    • Hurto, R.L.; Tong, A.H.; Boone, C.; Hopper, A.K. Inorganic phosphate deprivation causes tRNA nuclear accumulation via retrograde transport in Saccharomyces cerevisiae. Genetics 2007, 176, 841-852. [CrossRef] [PubMed]
    • (2007) Genetics , vol.176 , pp. 841-852
    • Hurto, R.L.1    Tong, A.H.2    Boone, C.3    Hopper, A.K.4
  • 112
    • 34250789855 scopus 로고    scopus 로고
    • Rapid and reversible nuclear accumulation of cytoplasmic tRNA in response to nutrient availability
    • [CrossRef] [PubMed]
    • Whitney, M.L.; Hurto, R.L.; Shaheen, H.H.; Hopper, A.K. Rapid and reversible nuclear accumulation of cytoplasmic tRNA in response to nutrient availability. Mol. Biol. Cell 2007, 18, 2678-2686. [CrossRef] [PubMed]
    • (2007) Mol. Biol. Cell , vol.18 , pp. 2678-2686
    • Whitney, M.L.1    Hurto, R.L.2    Shaheen, H.H.3    Hopper, A.K.4
  • 113
    • 84907222973 scopus 로고    scopus 로고
    • Separate responses of karyopherins to glucose and amino acid availability regulate nucleocytoplasmic transport
    • [CrossRef] [PubMed]
    • Huang, H.Y.; Hopper, A.K. Separate responses of karyopherins to glucose and amino acid availability regulate nucleocytoplasmic transport. Mol. Biol. Cell 2014, 25, 2840-2852. [CrossRef] [PubMed]
    • (2014) Mol. Biol. Cell , vol.25 , pp. 2840-2852
    • Huang, H.Y.1    Hopper, A.K.2
  • 114
    • 36248953763 scopus 로고    scopus 로고
    • Impaired tRNA nuclear export links DNA damage and cell-cycle checkpoint
    • [CrossRef] [PubMed]
    • Ghavidel, A.; Kislinger, T.; Pogoutse, O.; Sopko, R.; Jurisica, I.; Emili, A. Impaired tRNA nuclear export links DNA damage and cell-cycle checkpoint. Cell 2007, 131, 915-926. [CrossRef] [PubMed]
    • (2007) Cell , vol.131 , pp. 915-926
    • Ghavidel, A.1    Kislinger, T.2    Pogoutse, O.3    Sopko, R.4    Jurisica, I.5    Emili, A.6
  • 115
    • 80655144725 scopus 로고    scopus 로고
    • Maf1 protein, repressor of RNA polymerase III, indirectly affects tRNA processing
    • [CrossRef] [PubMed]
    • Karkusiewicz, I.; Turowski, T.W.; Graczyk, D.; Towpik, J.; Dhungel, N.; Hopper, A.K.; Boguta, M. Maf1 protein, repressor of RNA polymerase III, indirectly affects tRNA processing. J. Biol. Chem. 2011, 286, 39478-39488. [CrossRef] [PubMed]
    • (2011) J. Biol. Chem , vol.286 , pp. 39478-39488
    • Karkusiewicz, I.1    Turowski, T.W.2    Graczyk, D.3    Towpik, J.4    Dhungel, N.5    Hopper, A.K.6    Boguta, M.7
  • 116
    • 84893344050 scopus 로고    scopus 로고
    • Protein kinase a is part of a mechanism that regulates nuclear reimport of the nuclear tRNA export receptors Los1p and Msn5p
    • [CrossRef] [PubMed]
    • Pierce, J.B.; van der Merwe, G.; Mangroo, D. Protein kinase a is part of a mechanism that regulates nuclear reimport of the nuclear tRNA export receptors Los1p and Msn5p. Eukaryot. Cell 2014, 13, 209-230. [CrossRef] [PubMed]
    • (2014) Eukaryot. Cell , vol.13 , pp. 209-230
    • Pierce, J.B.1    Van Der Merwe, G.2    Mangroo, D.3
  • 117
    • 33749170007 scopus 로고    scopus 로고
    • The carrier Msn5p/Kap142p promotes nuclear export of theHsp70 Ssa4p and relocates in response to stress
    • [CrossRef] [PubMed]
    • Quan, X.; Tsoulos, P.; Kuritzky, A.; Zhang, R.; Stochaj, U. The carrier Msn5p/Kap142p promotes nuclear export of theHsp70 Ssa4p and relocates in response to stress. Mol. Microbiol. 2006, 62, 592-609. [CrossRef] [PubMed]
    • (2006) Mol. Microbiol , vol.62 , pp. 592-609
    • Quan, X.1    Tsoulos, P.2    Kuritzky, A.3    Zhang, R.4    Stochaj, U.5
  • 118
    • 34250165409 scopus 로고    scopus 로고
    • The localization of nuclear exporters of the importin-beta family is regulated by Snf1 kinase, nutrient supply and stress
    • [CrossRef] [PubMed]
    • Quan, X.; Yu, J.; Bussey, H.; Stochaj, U. The localization of nuclear exporters of the importin-beta family is regulated by Snf1 kinase, nutrient supply and stress. Biochim. Biophys. Acta 2007, 1773, 1052-1061. [CrossRef] [PubMed]
    • (2007) Biochim. Biophys. Acta , vol.1773 , pp. 1052-1061
    • Quan, X.1    Yu, J.2    Bussey, H.3    Stochaj, U.4
  • 119
    • 0037117614 scopus 로고    scopus 로고
    • Los1p-independent pathway for nuclear export of intronless tRNAs in Saccharomyces cerevisiae
    • [CrossRef] [PubMed]
    • Feng, W.; Hopper, A.K. A Los1p-independent pathway for nuclear export of intronless tRNAs in Saccharomyces cerevisiae. Proc. Natl. Acad. Sci. USA 2002, 99, 5412-5417. [CrossRef] [PubMed]
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 5412-5417
    • Feng, W.1    Hopper, A.2
  • 120
    • 0034767664 scopus 로고    scopus 로고
    • Role of nuclear pools of aminoacyl-tRNA synthetases in tRNA nuclear export
    • [CrossRef] [PubMed]
    • Azad, A.K.; Stanford, D.R.; Sarkar, S.; Hopper, A.K. Role of nuclear pools of aminoacyl-tRNA synthetases in tRNA nuclear export. Mol. Biol. Cell 2001, 12, 1381-1392. [CrossRef] [PubMed]
    • (2001) Mol. Biol. Cell , vol.12 , pp. 1381-1392
    • Azad, A.K.1    Stanford, D.R.2    Sarkar, S.3    Hopper, A.K.4
  • 121
    • 0033431040 scopus 로고    scopus 로고
    • Nuclear tRNA aminoacylation and its role in nuclear export of endogenous tRNAs in Saccharomyces cerevisiae
    • [CrossRef] [PubMed]
    • Sarkar, S.; Azad, A.K.; Hopper, A.K. Nuclear tRNA aminoacylation and its role in nuclear export of endogenous tRNAs in Saccharomyces cerevisiae. Proc. Natl. Acad. Sci. USA 1999, 96, 14366-14371. [CrossRef] [PubMed]
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 14366-14371
    • Sarkar, S.1    Azad, A.K.2    Hopper, A.K.3
  • 122
    • 24344499742 scopus 로고    scopus 로고
    • Depletion of Saccharomyces cerevisiae tRNA(His) guanylyltransferase Thg1p leads to uncharged tRNAhis with additional m(5)C
    • [CrossRef] [PubMed]
    • Gu, W.; Hurto, R.L.; Hopper, A.K.; Grayhack, E.J.; Phizicky, E.M. Depletion of Saccharomyces cerevisiae tRNA(His) guanylyltransferase Thg1p leads to uncharged tRNAhis with additional m(5)C. Mol. Cell Biol. 2005, 25, 8191-8201. [CrossRef] [PubMed]
    • (2005) Mol. Cell Biol , vol.25 , pp. 8191-8201
    • Gu, W.1    Hurto, R.L.2    Hopper, A.K.3    Grayhack, E.J.4    Phizicky, E.M.5
  • 123
    • 52949145277 scopus 로고    scopus 로고
    • tRNA cleavage is a conserved response to oxidative stress in eukaryotes
    • [CrossRef] [PubMed]
    • Thompson, D.M.; Lu, C.; Green, P.J.; Parker, R. tRNA cleavage is a conserved response to oxidative stress in eukaryotes. RNA 2008, 14, 2095-2103. [CrossRef] [PubMed]
    • (2008) RNA , vol.14 , pp. 2095-2103
    • Thompson, D.M.1    Lu, C.2    Green, P.J.3    Parker, R.4
  • 124
    • 0033974354 scopus 로고    scopus 로고
    • Anticodon nucleases
    • [CrossRef]
    • Kaufmann, G. Anticodon nucleases. Trends Biochem. Sci. 2000, 25, 70-74. [CrossRef]
    • (2000) Trends Biochem. Sci , vol.25 , pp. 70-74
    • Kaufmann, G.1
  • 125
    • 0036589213 scopus 로고    scopus 로고
    • The modes of action of colicins E5 and D, and related cytotoxic tRNAses
    • [CrossRef]
    • Masaki, H.; Ogawa, T. The modes of action of colicins E5 and D, and related cytotoxic tRNAses. Biochimie 2002, 84, 433-438. [CrossRef]
    • (2002) Biochimie , vol.84 , pp. 433-438
    • Masaki, H.1    Ogawa, T.2
  • 126
    • 84910673620 scopus 로고    scopus 로고
    • tRNA fragments in human health and disease
    • [CrossRef] [PubMed]
    • Anderson, P.; Ivanov, P. tRNA fragments in human health and disease. FEBS Lett. 2014, 588, 4297-4304. [CrossRef] [PubMed]
    • (2014) FEBS Lett , vol.588 , pp. 4297-4304
    • Anderson, P.1    Ivanov, P.2
  • 127
    • 84893147804 scopus 로고    scopus 로고
    • Slicing tRNAs to boost functional ncRNA diversity
    • [CrossRef] [PubMed]
    • Gebetsberger, J.; Polacek, N. Slicing tRNAs to boost functional ncRNA diversity. RNA Biol. 2013, 10, 1798-1806. [CrossRef] [PubMed]
    • (2013) RNA Biol , vol.10 , pp. 1798-1806
    • Gebetsberger, J.1    Polacek, N.2
  • 128
    • 67650604265 scopus 로고    scopus 로고
    • Stressing out over tRNA cleavage
    • [CrossRef] [PubMed]
    • Thompson, D.M.; Parker, R. Stressing out over tRNA cleavage. Cell 2009, 138, 215-219. [CrossRef] [PubMed]
    • (2009) Cell , vol.138 , pp. 215-219
    • Thompson, D.M.1    Parker, R.2
  • 129
    • 72749089855 scopus 로고    scopus 로고
    • A novel class of small RNAs: TRNA-derived RNA fragments (tRFs)
    • [CrossRef] [PubMed]
    • Lee, Y.S.; Shibata, Y.; Malhotra, A.; Dutta, A. A novel class of small RNAs: tRNA-derived RNA fragments (tRFs). Genes Dev. 2009, 23, 2639-2649. [CrossRef] [PubMed]
    • (2009) Genes Dev , vol.23 , pp. 2639-2649
    • Lee, Y.S.1    Shibata, Y.2    Malhotra, A.3    Dutta, A.4
  • 130
    • 58149498297 scopus 로고    scopus 로고
    • Stress induces tRNA cleavage by angiogenin in mammalian cells
    • [CrossRef] [PubMed]
    • Fu, H.; Feng, J.; Liu, Q.; Sun, F.; Tie, Y.; Zhu, J.; Xing, R.; Sun, Z.; Zheng, X. Stress induces tRNA cleavage by angiogenin in mammalian cells. FEBS Lett. 2009, 583, 437-442. [CrossRef] [PubMed]
    • (2009) FEBS Lett , vol.583 , pp. 437-442
    • Fu, H.1    Feng, J.2    Liu, Q.3    Sun, F.4    Tie, Y.5    Zhu, J.6    Xing, R.7    Sun, Z.8    Zheng, X.9
  • 131
    • 65249152479 scopus 로고    scopus 로고
    • The RNase Rny1p cleaves tRNAs and promotes cell death during oxidative stress in Saccharomyces cerevisiae
    • [CrossRef] [PubMed]
    • Thompson, D.M.; Parker, R. The RNase Rny1p cleaves tRNAs and promotes cell death during oxidative stress in Saccharomyces cerevisiae. J. Cell Biol. 2009, 185, 43-50. [CrossRef] [PubMed]
    • (2009) J. Cell Biol , vol.185 , pp. 43-50
    • Thompson, D.M.1    Parker, R.2
  • 132
    • 80051713296 scopus 로고    scopus 로고
    • Angiogenin-induced tRNA fragments inhibit translation initiation. Mol
    • [CrossRef] [PubMed]
    • Ivanov, P.; Emara, M.M.; Villen, J.; Gygi, S.P.; Anderson, P. Angiogenin-induced tRNA fragments inhibit translation initiation. Mol. Cell 2011, 43, 613-623. [CrossRef] [PubMed]
    • (2011) Cell , vol.43 , pp. 613-623
    • Ivanov, P.1    Emara, M.M.2    Villen, J.3    Gygi, S.P.4    Anderson, P.5
  • 133
    • 84919934354 scopus 로고    scopus 로고
    • G-quadruplex structures contribute to the neuroprotective effects of angiogenin-induced tRNA fragments
    • [CrossRef] [PubMed]
    • Ivanov, P.; O'Day, E.; Emara, M.M.; Wagner, G.; Lieberman, J.; Anderson, P. G-quadruplex structures contribute to the neuroprotective effects of angiogenin-induced tRNA fragments. Proc. Natl. Acad. Sci. USA 2014, 111, 18201-18206. [CrossRef] [PubMed]
    • (2014) Proc. Natl. Acad. Sci. USA , vol.111 , pp. 18201-18206
    • Ivanov, P.1    O'day, E.2    Emara, M.M.3    Wagner, G.4    Lieberman, J.5    Anderson, P.6
  • 134
    • 84901766882 scopus 로고    scopus 로고
    • Angiogenin-cleaved tRNA halves interact with cytochrome c, protecting cells from apoptosis during osmotic stress
    • [CrossRef] [PubMed]
    • Saikia, M.; Jobava, R.; Parisien, M.; Putnam, A.; Krokowski, D.; Gao, X.H.; Guan, B.J.; Yuan, Y.; Jankowsky, E.; Feng, Z.; et al. Angiogenin-cleaved tRNA halves interact with cytochrome c, protecting cells from apoptosis during osmotic stress. Mol. Cell Biol. 2014, 34, 2450-2463. [CrossRef] [PubMed]
    • (2014) Mol. Cell Biol , vol.34 , pp. 2450-2463
    • Saikia, M.1    Jobava, R.2    Parisien, M.3    Putnam, A.4    Krokowski, D.5    Gao, X.H.6    Guan, B.J.7    Yuan, Y.8    Jankowsky, E.9    Feng, Z.10
  • 135
    • 84857692673 scopus 로고    scopus 로고
    • Transfer RNA-derived fragments: Origins, processing, and functions
    • [CrossRef] [PubMed]
    • Sobala, A.; Hutvagner, G. Transfer RNA-derived fragments: Origins, processing, and functions. Wiley Interdiscip. Rev. RNA 2011, 2, 853-862. [CrossRef] [PubMed]
    • (2011) Wiley Interdiscip. Rev. RNA , vol.2 , pp. 853-862
    • Sobala, A.1    Hutvagner, G.2
  • 136
    • 84941358900 scopus 로고    scopus 로고
    • Dissecting tRNA-derived fragment complexities using personalized transcriptomes reveals novel fragment classes and unexpected dependencies
    • [CrossRef] [PubMed]
    • Telonis, A.G.; Loher, P.; Honda, S.; Jing, Y.; Palazzo, J.; Kirino, Y.; Rigoutsos, I. Dissecting tRNA-derived fragment complexities using personalized transcriptomes reveals novel fragment classes and unexpected dependencies. Oncotarget 2015, 6, 24797-24822. [CrossRef] [PubMed]
    • (2015) Oncotarget , vol.6 , pp. 24797-24822
    • Telonis, A.G.1    Loher, P.2    Honda, S.3    Jing, Y.4    Palazzo, J.5    Kirino, Y.6    Rigoutsos, I.7
  • 138
    • 84896859718 scopus 로고    scopus 로고
    • Argonaute-bound small RNAs from promoter-proximal RNA polymerase II
    • [CrossRef] [PubMed]
    • Zamudio, J.R.; Kelly, T.J.; Sharp, P.A. Argonaute-bound small RNAs from promoter-proximal RNA polymerase II. Cell 2014, 156, 920-934. [CrossRef] [PubMed]
    • (2014) Cell , vol.156 , pp. 920-934
    • Zamudio, J.R.1    Kelly, T.J.2    Sharp, P.A.3
  • 139
    • 84872784032 scopus 로고    scopus 로고
    • tRNA-derived fragments target the ribosome and function as regulatory non-coding RNA in Haloferax volcanii
    • [CrossRef] [PubMed]
    • Gebetsberger, J.; Zywicki, M.; Kunzi, A.; Polacek, N. tRNA-derived fragments target the ribosome and function as regulatory non-coding RNA in Haloferax volcanii. Archaea 2012, 2012, 260909. [CrossRef] [PubMed]
    • (2012) Archaea , vol.2012 , pp. 260909
    • Gebetsberger, J.1    Zywicki, M.2    Kunzi, A.3    Polacek, N.4
  • 140
    • 66149125192 scopus 로고    scopus 로고
    • The phloem-delivered RNA pool contains small noncoding RNAs and interferes with translation
    • [CrossRef] [PubMed]
    • Zhang, S.; Sun, L.; Kragler, F. The phloem-delivered RNA pool contains small noncoding RNAs and interferes with translation. Plant Physiol. 2009, 150, 378-387. [CrossRef] [PubMed]
    • (2009) Plant Physiol , vol.150 , pp. 378-387
    • Zhang, S.1    Sun, L.2    Kragler, F.3
  • 142
    • 84955486679 scopus 로고    scopus 로고
    • Sperm tsRNAs contribute to intergenerational inheritance of an acquired metabolic disorder
    • [CrossRef] [PubMed]
    • Chen, Q.; Yan, M.; Cao, Z.; Li, X.; Zhang, Y.; Shi, J.; Feng, G.H.; Peng, H.; Zhang, X.; Zhang, Y.; et al. Sperm tsRNAs contribute to intergenerational inheritance of an acquired metabolic disorder. Science 2016, 351, 397-400. [CrossRef] [PubMed]
    • (2016) Science , vol.351 , pp. 397-400
    • Chen, Q.1    Yan, M.2    Cao, Z.3    Li, X.4    Zhang, Y.5    Shi, J.6    Feng, G.H.7    Peng, H.8    Zhang, X.9    Zhang, Y.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.