An adenosine deaminase that generates inosine at the wobble position of tRNAs

Science

Volumn 286, Issue 5442, 1999, Pages 1146-1149

  Gerber, André P ^a   Keller, Walter ^a  

^a UNIVERSITY OF BASEL   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE DEAMINASE; CYTIDINE DEAMINASE; INOSINE; TRANSFER RNA;

ARTICLE; ENZYME ANALYSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DOMAIN; SACCHAROMYCES CEREVISIAE; SEQUENCE HOMOLOGY;

ADENOSINE DEAMINASE; AMINO ACID MOTIFS; AMINO ACID SEQUENCE; ANTICODON; CYTIDINE DEAMINASE; DIMERIZATION; EVOLUTION, MOLECULAR; GENES, ESSENTIAL; GENES, FUNGAL; INOSINE; MOLECULAR SEQUENCE DATA; MUTATION; RNA, FUNGAL; RNA, TRANSFER; SACCHAROMYCES CEREVISIAE; SEQUENCE ALIGNMENT;

SACCHAROMYCES CEREVISIAE;

EID: 0033527628     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.286.5442.1146     Document Type: Article

References (35)

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35. We thank H. Langen (Hoffmann La-Roche) for the mass spectrometry analysis; H. Grosjean, J. Atkins, and H. Himeno for the tRNA templates; and members of our laboratory and M. A. O'Connell for critical reading of the manuscript Supported by Boehringer Ingelheim Fonds (A.P.G.), the University of Basel, the Swiss National Science Foundation, the Human Frontiers Science Program, and the Louis-Jeantet Foundation for Medicine.