Codon-biased translation can be regulated by wobble-base tRNA modification systems during cellular stress responses

RNA Biology

Volumn 12, Issue 6, 2015, Pages 603-614

  Endres, Lauren ^a   Dedon, Peter C ^b,c   Begley, Thomas J ^a,d  

^a SUNY POLYTECHNIC INSTITUTE   (United States)

^b Massachusetts Institute of Technology   (United States)

^c SINGAPORE MIT ALLIANCE FOR RESEARCH AND TECHNOLOGY   (Singapore)

^d STATE UNIVERSITY OF NEW YORK   (United States)

Author keywords

Anticodon; Codon bias; Gene expression; Stress response; Translation; TRNA methyltransferase; TRNA modification

Indexed keywords

ADENINE; AMINO ACID TRANSFER RNA LIGASE; CYTOSINE; DNA DIRECTED RNA POLYMERASE III; GUANINE; HEAT SHOCK PROTEIN; PHOSPHOPROTEIN PHOSPHATASE 2A; PROTEIN P53; PSEUDOURIDINE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); RIBONUCLEASE P; RIBONUCLEOTIDE REDUCTASE; SELENOCYSTEINE; SIGNAL PEPTIDE; TRANSFER RNA; TRANSFER RNA METHYLTRANSFERASE; URACIL; CODON;

AMINOACYLATION; ANTICODON; ARTICLE; BIOGENESIS; CELL CYCLE PROGRESSION; CELL CYCLE S PHASE; CELL PROLIFERATION; CELLULAR STRESS RESPONSE; CODON; COLONY FORMATION; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DNA DAMAGE; DNA REPLICATION; G1 PHASE CELL CYCLE CHECKPOINT; GENE EXPRESSION; GENETIC ASSOCIATION; GENETIC CODE; GENETIC TRANSCRIPTION; HUMAN; MELAS SYNDROME; MERRF SYNDROME; NEOPLASM; OXIDATIVE STRESS; POINT MUTATION; PROTEIN EXPRESSION; PROTEIN SECONDARY STRUCTURE; PROTEIN SYNTHESIS; REGULATORY MECHANISM; RIBOSOME; RNA ISOLATION; RNA STRUCTURE; RNA TRANSLATION; STOP CODON; TUMOR GROWTH; TUMOR VOLUME; TURNOVER TIME; WOBBLE BASE TRNA MODIFICATION SYSTEM; ANIMAL; CELL FUNCTION; CHEMISTRY; METABOLISM; PHYSIOLOGICAL STRESS;

AMINOACYLATION; ANIMALS; CELL PHYSIOLOGICAL PHENOMENA; CODON; HUMANS; NEOPLASMS; PROTEIN BIOSYNTHESIS; REACTIVE OXYGEN SPECIES; RNA, TRANSFER; STRESS, PHYSIOLOGICAL;

EID: 84944680246     PISSN: 15476286     EISSN: 15558584     Source Type: Journal    
DOI: 10.1080/15476286.2015.1031947     Document Type: Article

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