CRISPR library designer (CLD): Software for multispecies design of single guide RNA libraries

Genome Biology

Volumn 17, Issue 1, 2016, Pages

  Heigwer, Florian ^a   Zhan, Tianzuo ^a,b   Breinig, Marco ^a   Winter, Jan ^a   Brügemann, Dirk ^a   Leible, Svenja ^a   Boutros, Michael ^a  

^a GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^b UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

Bioinformatics; CRISPR Cas9; Functional genomics; Pooled screens; SgRNA design

Indexed keywords

TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; GUIDE RNA;

ARTICLE; BIOINFORMATICS; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEAT LIBRARY DESIGNER SOFRWARE; COMPUTER PROGRAM; CONTROLLED STUDY; CRISPR CAS SYSTEM; GENOME ANALYSIS; HUMAN; MOLECULAR DYNAMICS; PROMOTER REGION; RNA STRUCTURE; SIGNAL TRANSDUCTION; VALIDATION PROCESS; ANIMAL; BIOLOGY; GENE LIBRARY; GENETICS; PROCEDURES; SOFTWARE;

ANIMALS; COMPUTATIONAL BIOLOGY; CRISPR-CAS SYSTEMS; GENE LIBRARY; HUMANS; RNA, GUIDE; SOFTWARE; TNF-RELATED APOPTOSIS-INDUCING LIGAND;

EID: 84961626370     PISSN: 14747596     EISSN: 1474760X     Source Type: Journal    
DOI: 10.1186/s13059-016-0915-2     Document Type: Article

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