Inactivation of nuclear GSK3β by Ser389 phosphorylation promotes lymphocyte fitness during DNA double-strand break response

Nature Communications

Volumn 7, Issue , 2016, Pages

  Thornton, Tina M ^a   Delgado, Pilar ^b   Chen, Liang ^c   Salas, Beatriz ^a   Krementsov, Dimitry ^a   Fernandez, Miriam ^a   Vernia, Santiago ^d   Davis, Roger J ^d,e   Heimann, Ruth ^a   Teuscher, Cory ^a   Krangel, Michael S ^c   Ramiro, Almudena R ^b   Rincón, Mercedes ^a  

^a UNIVERSITY OF VERMONT   (United States)

^b CENTRO NACIONAL DE INVESTIGACIONES CARDIOVASCULARES CNIC   (Spain)

^c DUKE UNIVERSITY MEDICAL CENTER   (United States)

^d UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^e HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ATM PROTEIN; DOUBLE STRANDED DNA; GLYCOGEN SYNTHASE KINASE 3BETA; IMMUNOGLOBULIN G; MITOGEN ACTIVATED PROTEIN KINASE P38; SERINE; T LYMPHOCYTE RECEPTOR BETA CHAIN; THREONINE; GLYCOGEN SYNTHASE KINASE 3; GSK3B PROTEIN, HUMAN; GSK3B PROTEIN, MOUSE;

ANTIBODY; ANTIGEN; CELLS AND CELL COMPONENTS; ENZYME ACTIVITY; GENE EXPRESSION; IMMUNE RESPONSE; IMMUNIZATION; METABOLISM; RECOMBINATION; RODENT;

ADAPTIVE IMMUNITY; ANIMAL CELL; ANIMAL EXPERIMENT; ANTIBODY RESPONSE; ARTICLE; CELL SURVIVAL; CONTROLLED STUDY; DNA REPAIR; DOUBLE STRANDED DNA BREAK; ENZYME ACTIVITY; ENZYME INACTIVATION; ENZYME PHOSPHORYLATION; ENZYME REGULATION; GENE REARRANGEMENT; LYMPHOCYTE; MOUSE; NONHUMAN; VDJ RECOMBINATION; ANIMAL; CELL CULTURE; GENE EXPRESSION REGULATION; GENE TARGETING; GENETICS; HUMAN; METABOLISM; MUTATION; PHOSPHORYLATION; PHYSIOLOGY;

MUS;

ANIMALS; CELLS, CULTURED; DNA BREAKS, DOUBLE-STRANDED; DNA REPAIR; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE KNOCK-IN TECHNIQUES; GLYCOGEN SYNTHASE KINASE 3; GLYCOGEN SYNTHASE KINASE 3 BETA; HUMANS; LYMPHOCYTES; MICE; MUTATION; PHOSPHORYLATION;

EID: 84961365671     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms10553     Document Type: Article

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