Antagonism between MCL-1 and PUMA governs stem/progenitor cell survival during hematopoietic recovery from stress

Blood

Volumn 125, Issue 21, 2015, Pages 3273-3280

  Delbridge, Alex R D ^a,b   Opferman, Joseph T ^c   Grabow, Stephanie ^a,b   Strasser, Andreas ^a,b  

^a WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

^c ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FLUOROURACIL; PROTEIN MCL 1; PUMA PROTEIN; APOPTOSIS REGULATORY PROTEIN; MCL1 PROTEIN, MOUSE; PUMA PROTEIN, MOUSE; TUMOR SUPPRESSOR PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE MARROW TRANSPLANTATION; CELL REGENERATION; CELL SURVIVAL; CONTROLLED STUDY; FEMALE; HAPLOINSUFFICIENCY; HEMATOPOIESIS; HEMATOPOIETIC SYSTEM; MALE; MOLECULAR MECHANICS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; STEM CELL; ANIMAL; APOPTOSIS; C57BL MOUSE; CELL SEPARATION; FLOW CYTOMETRY; HEMATOPOIETIC STEM CELL; KNOCKOUT MOUSE; METABOLISM; PHYSIOLOGICAL STRESS; PHYSIOLOGY;

ANIMALS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; CELL SEPARATION; CELL SURVIVAL; FLOW CYTOMETRY; HEMATOPOIETIC STEM CELLS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MYELOID CELL LEUKEMIA SEQUENCE 1 PROTEIN; STRESS, PHYSIOLOGICAL; TUMOR SUPPRESSOR PROTEINS;

EID: 84956527699     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2015-01-621250     Document Type: Article

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