Dual functions of Nbs1 in the repair of DNA breaks and proliferation ensure proper V(D)J recombination and T-cell development

Molecular and Cellular Biology

Volumn 30, Issue 23, 2010, Pages 5572-5581

  Saidi, Amal ^a   Li, Tangliang ^a   Weih, Falk ^a,b   Concannon, Patrick ^c   Wang, Zhao Qi ^a,b  

^a FRITZ LIPMANN INSTITUTE   (Germany)

^b FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

^c UNIVERSITY OF VIRGINIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MRE11 PROTEIN; NIBRIN; PROTEIN P53; RAD50 PROTEIN; RAG1 PROTEIN; RAG2 PROTEIN; T LYMPHOCYTE RECEPTOR BETA CHAIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL EXPANSION; CELL LOSS; CELL MATURATION; CELL PROLIFERATION; CHROMATIN; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DNA CLEAVAGE; DNA RECOMBINATION; DNA REPAIR; DNA STRAND BREAKAGE; GENE DELETION; LYMPHOCYTOPENIA; MOUSE; NONHUMAN; PRE T LYMPHOCYTE; PRIORITY JOURNAL; PROTEIN FUNCTION; T LYMPHOCYTE;

ANIMALS; BASE SEQUENCE; CELL CYCLE PROTEINS; CELL DIFFERENTIATION; CELL PROLIFERATION; DISEASE MODELS, ANIMAL; DNA BREAKS; DNA PRIMERS; DNA REPAIR; GENE REARRANGEMENT, ALPHA-CHAIN T-CELL ANTIGEN RECEPTOR; GENE REARRANGEMENT, BETA-CHAIN T-CELL ANTIGEN RECEPTOR; GENES, IMMUNOGLOBULIN HEAVY CHAIN; GENES, P53; HUMANS; LYMPHOPENIA; MICE; MICE, KNOCKOUT; MUTATION; NIJMEGEN BREAKAGE SYNDROME; NUCLEAR PROTEINS; RECOMBINATION, GENETIC; T-LYMPHOCYTES;

MUS;

EID: 78649730157     PISSN: 02707306     EISSN: 10985549     Source Type: Journal    
DOI: 10.1128/MCB.00917-10     Document Type: Article

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