메뉴 건너뛰기




Volumn 110, Issue 34, 2013, Pages

Unifying model for molecular determinants of the preselection Vβ repertoire

Author keywords

Gene regulation; Lymphocytes; T cell receptor

Indexed keywords

AGR PROTEIN; DBETAJBETA PROTEIN; LYMPHOCYTE ANTIGEN RECEPTOR; MESSENGER RNA; PROTEIN; SIGNAL PEPTIDE; T LYMPHOCYTE RECEPTOR BETA CHAIN; UNCLASSIFIED DRUG; VBETA PROTEIN;

EID: 84882755183     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1304048110     Document Type: Article
Times cited : (44)

References (60)
  • 1
    • 41349089522 scopus 로고    scopus 로고
    • Gene regulation in the third dimension
    • Dekker J (2008) Gene regulation in the third dimension. Science 319(5871):1793-1794.
    • (2008) Science , vol.319 , Issue.5871 , pp. 1793-1794
    • Dekker, J.1
  • 2
    • 84874438729 scopus 로고    scopus 로고
    • Tcra gene recombination is supported by a Tcra enhancer- and CTCF-dependent chromatin hub
    • Shih HY, et al. (2012) Tcra gene recombination is supported by a Tcra enhancer- and CTCF-dependent chromatin hub. Proc Natl Acad Sci USA 109(50):E3493-E3502.
    • (2012) Proc Natl Acad Sci USA , vol.109 , Issue.50
    • Shih, H.Y.1
  • 3
    • 84859383686 scopus 로고    scopus 로고
    • Chromatin topology and the regulation of antigen receptor assembly
    • Bossen C, Mansson R, Murre C (2012) Chromatin topology and the regulation of antigen receptor assembly. Annu Rev Immunol 30:337-356.
    • (2012) Annu Rev Immunol , vol.30 , pp. 337-356
    • Bossen, C.1    Mansson, R.2    Murre, C.3
  • 4
    • 0036240127 scopus 로고    scopus 로고
    • The mechanism and regulation of chromosomal v (D)J recombination
    • Bassing CH, Swat W, Alt FW (2002) The mechanism and regulation of chromosomal V (D)J recombination. Cell 109(Suppl):S45-S55.
    • (2002) Cell , vol.109 , Issue.SUPPL.
    • Bassing, C.H.1    Swat, W.2    Alt, F.W.3
  • 5
    • 79953164038 scopus 로고    scopus 로고
    • Recombination centres and the orchestration of V(D) J recombination
    • Schatz DG, Ji Y (2011) Recombination centres and the orchestration of V(D)J recombination. Nat Rev Immunol 11(4):251-263.
    • (2011) Nat Rev Immunol , vol.11 , Issue.4 , pp. 251-263
    • Schatz, D.G.1    Ji, Y.2
  • 7
    • 70349560864 scopus 로고    scopus 로고
    • Genetic and epigenetic control of v gene rearrangement frequency
    • Feeney AJ (2009) Genetic and epigenetic control of V gene rearrangement frequency. Adv Exp Med Biol 650:73-81.
    • (2009) Adv Exp Med Biol , vol.650 , pp. 73-81
    • Feeney, A.J.1
  • 8
    • 35349024178 scopus 로고    scopus 로고
    • A plant homeodomain in RAG-2 that binds Hypermethylated lysine 4 of histone H3 is necessary for efficient antigen-receptor-gene rearrangement
    • Liu Y, Subrahmanyam R, Chakraborty T, Sen R, Desiderio S (2007) A plant homeodomain in RAG-2 that binds Hypermethylated lysine 4 of histone H3 is necessary for efficient antigen-receptor-gene rearrangement. Immunity 27(4):561-571.
    • (2007) Immunity , vol.27 , Issue.4 , pp. 561-571
    • Liu, Y.1    Subrahmanyam, R.2    Chakraborty, T.3    Sen, R.4    Desiderio, S.5
  • 9
    • 37249041657 scopus 로고    scopus 로고
    • RAG2 PHD finger couples histone H3 lysine 4 trimethylation with V(D)J recombination
    • Matthews AG, et al. (2007) RAG2 PHD finger couples histone H3 lysine 4 trimethylation with V(D)J recombination. Nature 450(7172):1106-1110.
    • (2007) Nature , vol.450 , Issue.7172 , pp. 1106-1110
    • Matthews, A.G.1
  • 10
    • 33646007633 scopus 로고    scopus 로고
    • Regulation of TCRbeta gene assembly by a promoter/enhancer holocomplex
    • Oestreich KJ, et al. (2006) Regulation of TCRbeta gene assembly by a promoter/enhancer holocomplex. Immunity 24(4):381-391.
    • (2006) Immunity , vol.24 , Issue.4 , pp. 381-391
    • Oestreich, K.J.1
  • 11
    • 77951893700 scopus 로고    scopus 로고
    • The in vivo pattern of binding of RAG1 and RAG2 to antigen receptor loci
    • Ji Y, et al. (2010) The in vivo pattern of binding of RAG1 and RAG2 to antigen receptor loci. Cell 141(3):419-431.
    • (2010) Cell , vol.141 , Issue.3 , pp. 419-431
    • Ji, Y.1
  • 12
    • 13444268486 scopus 로고    scopus 로고
    • Regulation of T cell receptor beta allelic exclusion at a level beyond accessibility
    • Jackson A, Kondilis HD, Khor B, Sleckman BP, Krangel MS (2005) Regulation of T cell receptor beta allelic exclusion at a level beyond accessibility. Nat Immunol 6(2): 189-197.
    • (2005) Nat Immunol , vol.6 , Issue.2 , pp. 189-197
    • Jackson, A.1    Kondilis, H.D.2    Khor, B.3    Sleckman, B.P.4    Krangel, M.S.5
  • 13
    • 80054702528 scopus 로고    scopus 로고
    • Two forms of loops generate the chromatin conformation of the immunoglobulin heavy-chain gene locus
    • Guo C, et al. (2011) Two forms of loops generate the chromatin conformation of the immunoglobulin heavy-chain gene locus. Cell 147(2):332-343.
    • (2011) Cell , vol.147 , Issue.2 , pp. 332-343
    • Guo, C.1
  • 14
    • 41949121201 scopus 로고    scopus 로고
    • The 3D structure of the immunoglobulin heavy-chain locus: Implications for long-range genomic interactions
    • Jhunjhunwala S, et al. (2008) The 3D structure of the immunoglobulin heavy-chain locus: Implications for long-range genomic interactions. Cell 133(2):265-279.
    • (2008) Cell , vol.133 , Issue.2 , pp. 265-279
    • Jhunjhunwala, S.1
  • 15
    • 34248583377 scopus 로고    scopus 로고
    • Reversible contraction by looping of the Tcra and Tcrb loci in rearranging thymocytes
    • Skok JA, et al. (2007) Reversible contraction by looping of the Tcra and Tcrb loci in rearranging thymocytes. Nat Immunol 8(4):378-387.
    • (2007) Nat Immunol , vol.8 , Issue.4 , pp. 378-387
    • Skok, J.A.1
  • 16
    • 46149113242 scopus 로고    scopus 로고
    • CTCF physically links cohesin to chromatin
    • Rubio ED, et al. (2008) CTCF physically links cohesin to chromatin. Proc Natl Acad Sci USA 105(24):8309-8314.
    • (2008) Proc Natl Acad Sci USA , vol.105 , Issue.24 , pp. 8309-8314
    • Rubio, E.D.1
  • 17
    • 80052042965 scopus 로고    scopus 로고
    • A role for cohesin in T-cell-receptor rearrangement and thymocyte differentiation
    • Seitan VC, et al. (2011) A role for cohesin in T-cell-receptor rearrangement and thymocyte differentiation. Nature 476(7361):467-471.
    • (2011) Nature , vol.476 , Issue.7361 , pp. 467-471
    • Seitan, V.C.1
  • 18
    • 80755180849 scopus 로고    scopus 로고
    • The DNA-binding protein CTCF limits proximal Vκ recombination and restricts κ enhancer interactions to the immunoglobulin κ light chain locus
    • Ribeiro de Almeida C, et al. (2011) The DNA-binding protein CTCF limits proximal Vκ recombination and restricts κ enhancer interactions to the immunoglobulin κ light chain locus. Immunity 35(4):501-513.
    • (2011) Immunity , vol.35 , Issue.4 , pp. 501-513
    • Ribeiro De Almeida, C.1
  • 19
    • 80053130223 scopus 로고    scopus 로고
    • CTCF-binding elements mediate control of V(D)J recombination
    • Guo C, et al. (2011) CTCF-binding elements mediate control of V(D)J recombination. Nature 477(7365):424-430.
    • (2011) Nature , vol.477 , Issue.7365 , pp. 424-430
    • Guo, C.1
  • 20
    • 79955525583 scopus 로고    scopus 로고
    • A multifunctional element in the mouse Igκ locus that specifies repertoire and Ig loci subnuclear location
    • Xiang Y, Zhou X, Hewitt SL, Skok JA, Garrard WT (2011) A multifunctional element in the mouse Igκ locus that specifies repertoire and Ig loci subnuclear location. J Immunol 186(9):5356-5366.
    • (2011) J Immunol , vol.186 , Issue.9 , pp. 5356-5366
    • Xiang, Y.1    Zhou, X.2    Hewitt, S.L.3    Skok, J.A.4    Garrard, W.T.5
  • 22
    • 84866842507 scopus 로고    scopus 로고
    • Chromatin conformation governs T-cell receptor Jβ gene segment usage
    • Ndifon W, et al. (2012) Chromatin conformation governs T-cell receptor Jβ gene segment usage. Proc Natl Acad Sci USA 109(39):15865-15870.
    • (2012) Proc Natl Acad Sci USA , vol.109 , Issue.39 , pp. 15865-15870
    • Ndifon, W.1
  • 23
    • 77950541195 scopus 로고    scopus 로고
    • Comprehensive assessment of T-cell receptor beta-chain diversity in alphabeta T cells
    • Robins HS, et al. (2009) Comprehensive assessment of T-cell receptor beta-chain diversity in alphabeta T cells. Blood 114(19):4099-4107.
    • (2009) Blood , vol.114 , Issue.19 , pp. 4099-4107
    • Robins, H.S.1
  • 24
    • 0035160218 scopus 로고    scopus 로고
    • Biased v beta usage in immature thymocytes is independent of DJ beta proximity and pT alpha pairing
    • Wilson A, Maréchal C, MacDonald HR (2001) Biased V beta usage in immature thymocytes is independent of DJ beta proximity and pT alpha pairing. J Immunol 166(1):51-57.
    • (2001) J Immunol , vol.166 , Issue.1 , pp. 51-57
    • Wilson, A.1    Maréchal, C.2    MacDonald, H.R.3
  • 25
    • 0037023361 scopus 로고    scopus 로고
    • Subnuclear compartmentalization of immunoglobulin loci during lymphocyte development
    • Kosak ST, et al. (2002) Subnuclear compartmentalization of immunoglobulin loci during lymphocyte development. Science 296(5565):158-162.
    • (2002) Science , vol.296 , Issue.5565 , pp. 158-162
    • Kosak, S.T.1
  • 26
    • 1542343974 scopus 로고    scopus 로고
    • Pax5 induces V-to-DJ rearrangements and locus contraction of the immunoglobulin heavy-chain gene
    • Fuxa M, et al. (2004) Pax5 induces V-to-DJ rearrangements and locus contraction of the immunoglobulin heavy-chain gene. Genes Dev 18(4):411-422.
    • (2004) Genes Dev , vol.18 , Issue.4 , pp. 411-422
    • Fuxa, M.1
  • 27
    • 47849118209 scopus 로고    scopus 로고
    • Regulation of B cell fate commitment and immunoglobulin heavy-chain gene rearrangements by Ikaros
    • Reynaud D, et al. (2008) Regulation of B cell fate commitment and immunoglobulin heavy-chain gene rearrangements by Ikaros. Nat Immunol 9(8):927-936.
    • (2008) Nat Immunol , vol.9 , Issue.8 , pp. 927-936
    • Reynaud, D.1
  • 28
    • 34249035911 scopus 로고    scopus 로고
    • Yin Yang 1 is a critical regulator of B-cell development
    • Liu H, et al. (2007) Yin Yang 1 is a critical regulator of B-cell development. Genes Dev 21(10):1179-1189.
    • (2007) Genes Dev , vol.21 , Issue.10 , pp. 1179-1189
    • Liu, H.1
  • 29
    • 84869502375 scopus 로고    scopus 로고
    • Global changes in the nuclear positioning of genes and intra- and interdomain genomic interactions that orchestrate B cell fate
    • Lin YC, et al. (2012) Global changes in the nuclear positioning of genes and intra- and interdomain genomic interactions that orchestrate B cell fate. Nat Immunol 13(12): 1196-1204.
    • (2012) Nat Immunol , vol.13 , Issue.12 , pp. 1196-1204
    • Lin, Y.C.1
  • 30
    • 84874283254 scopus 로고    scopus 로고
    • Higher-order looping and nuclear organization of Tcra facilitate targeted rag cleavage and regulated rearrangement in recombination centers
    • Chaumeil J, et al. (2013) Higher-order looping and nuclear organization of Tcra facilitate targeted rag cleavage and regulated rearrangement in recombination centers. Cell Rep 3(2):359-370.
    • (2013) Cell Rep , vol.3 , Issue.2 , pp. 359-370
    • Chaumeil, J.1
  • 31
    • 0034595205 scopus 로고    scopus 로고
    • TCRalpha enhancer activation occurs via a conformational change of a pre-assembled nucleo-protein complex
    • Spicuglia S, et al. (2000) TCRalpha enhancer activation occurs via a conformational change of a pre-assembled nucleo-protein complex. EMBO J 19(9):2034-2045.
    • (2000) EMBO J , vol.19 , Issue.9 , pp. 2034-2045
    • Spicuglia, S.1
  • 32
    • 0024691453 scopus 로고
    • V(D)J recombination: A functional definition of the joining signals
    • Hesse JE, Lieber MR, Mizuuchi K, Gellert M (1989) V(D)J recombination: A functional definition of the joining signals. Genes Dev 3(7):1053-1061.
    • (1989) Genes Dev , vol.3 , Issue.7 , pp. 1053-1061
    • Hesse, J.E.1    Lieber, M.R.2    Mizuuchi, K.3    Gellert, M.4
  • 33
    • 0042831182 scopus 로고    scopus 로고
    • Evolutionarily conserved pattern of gene segment usage within the mammalian TCRbeta locus
    • Livák F (2003) Evolutionarily conserved pattern of gene segment usage within the mammalian TCRbeta locus. Immunogenetics 55(5):307-314.
    • (2003) Immunogenetics , vol.55 , Issue.5 , pp. 307-314
    • Livák, F.1
  • 34
    • 0028351920 scopus 로고
    • Level of human TCRBV3S1 (V beta 3) expression correlates with allelic polymorphism in the spacer region of the recombination signal sequence
    • Posnett DN, et al. (1994) Level of human TCRBV3S1 (V beta 3) expression correlates with allelic polymorphism in the spacer region of the recombination signal sequence. J Exp Med 179(5):1707-1711.
    • (1994) J Exp Med , vol.179 , Issue.5 , pp. 1707-1711
    • Posnett, D.N.1
  • 35
    • 0037243276 scopus 로고    scopus 로고
    • Dramatically increased rearrangement and peripheral representation of Vbeta14 driven by the 3'Dbeta1 recombination signal sequence
    • Wu C, et al. (2003) Dramatically increased rearrangement and peripheral representation of Vbeta14 driven by the 3'Dbeta1 recombination signal sequence. Immunity 18(1):75-85.
    • (2003) Immunity , vol.18 , Issue.1 , pp. 75-85
    • Wu, C.1
  • 36
    • 0032400975 scopus 로고    scopus 로고
    • Decreased frequency of rearrangement due to the synergistic effect of nucleotide changes in the heptamer and nonamer of the recombination signal sequence of the v kappa gene A2b, which is associated with increased susceptibility of Navajos to Haemophilus influenzae type b disease
    • Nadel B, et al. (1998) Decreased frequency of rearrangement due to the synergistic effect of nucleotide changes in the heptamer and nonamer of the recombination signal sequence of the V kappa gene A2b, which is associated with increased susceptibility of Navajos to Haemophilus influenzae type b disease. J Immunol 161(11):6068-6073.
    • (1998) J Immunol , vol.161 , Issue.11 , pp. 6068-6073
    • Nadel, B.1
  • 37
    • 0033918155 scopus 로고    scopus 로고
    • B-cell repertoire formation: Role of the recombination signal sequence in non-random v segment utilization
    • Feeney AJ, Tang A, Ogwaro KM (2000) B-cell repertoire formation: Role of the recombination signal sequence in non-random V segment utilization. Immunol Rev 175:59-69.
    • (2000) Immunol Rev , vol.175 , pp. 59-69
    • Feeney, A.J.1    Tang, A.2    Ogwaro, K.M.3
  • 38
    • 0037242580 scopus 로고    scopus 로고
    • Extrachromosomal recombination substrates recapitulate beyond 12/23 restricted VDJ recombination in nonlymphoid cells
    • Jung D, et al. (2003) Extrachromosomal recombination substrates recapitulate beyond 12/23 restricted VDJ recombination in nonlymphoid cells. Immunity 18(1):65-74.
    • (2003) Immunity , vol.18 , Issue.1 , pp. 65-74
    • Jung, D.1
  • 39
    • 0037454957 scopus 로고    scopus 로고
    • Prospective estimation of recombination signal efficiency and identification of functional cryptic signals in the genome by statistical modeling
    • Cowell LG, Davila M, Yang K, Kepler TB, Kelsoe G (2003) Prospective estimation of recombination signal efficiency and identification of functional cryptic signals in the genome by statistical modeling. J Exp Med 197(2):207-220.
    • (2003) J Exp Med , vol.197 , Issue.2 , pp. 207-220
    • Cowell, L.G.1    Davila, M.2    Yang, K.3    Kepler, T.B.4    Kelsoe, G.5
  • 40
    • 3242875994 scopus 로고    scopus 로고
    • A functional analysis of the spacer of V(D)J recombination signal sequences
    • Lee AI, et al. (2003) A functional analysis of the spacer of V(D)J recombination signal sequences. PLoS Biol 1(1):E1.
    • (2003) PLoS Biol , vol.1 , Issue.1
    • Lee, A.I.1
  • 41
    • 0029814965 scopus 로고    scopus 로고
    • DNA sequence and structure requirements for cleavage of V(D)J recombination signal sequences
    • Cuomo CA, Mundy CL, Oettinger MA (1996) DNA sequence and structure requirements for cleavage of V(D)J recombination signal sequences. Mol Cell Biol 16(10):5683-5690.
    • (1996) Mol Cell Biol , vol.16 , Issue.10 , pp. 5683-5690
    • Cuomo, C.A.1    Mundy, C.L.2    Oettinger, M.A.3
  • 42
    • 0027237601 scopus 로고
    • Coding end sequence can markedly affect the initiation of V(D)J recombination
    • Gerstein RM, Lieber MR (1993) Coding end sequence can markedly affect the initiation of V(D)J recombination. Genes Dev 7(7B):1459-1469.
    • (1993) Genes Dev , vol.7 , Issue.7 B , pp. 1459-1469
    • Gerstein, R.M.1    Lieber, M.R.2
  • 43
    • 0141920616 scopus 로고    scopus 로고
    • DNA-Rag protein interactions in the control of selective D gene utilization in the TCR beta locus
    • Olaru A, Patterson DN, Villey I, Livák F (2003) DNA-Rag protein interactions in the control of selective D gene utilization in the TCR beta locus. J Immunol 171(7): 3605-3611.
    • (2003) J Immunol , vol.171 , Issue.7 , pp. 3605-3611
    • Olaru, A.1    Patterson, D.N.2    Villey, I.3    Livák, F.4
  • 44
    • 0033512850 scopus 로고    scopus 로고
    • Mechanistic basis for coding end sequence effects in the initiation of V(D)J recombination
    • Yu K, Lieber MR (1999) Mechanistic basis for coding end sequence effects in the initiation of V(D)J recombination. Mol Cell Biol 19(12):8094-8102.
    • (1999) Mol Cell Biol , vol.19 , Issue.12 , pp. 8094-8102
    • Yu, K.1    Lieber, M.R.2
  • 45
    • 66749124789 scopus 로고    scopus 로고
    • H3K4me3 stimulates the V(D)J RAG complex for both nicking and hairpinning in trans in addition to tethering in cis: Implications for translocations
    • Shimazaki N, Tsai AG, Lieber MR (2009) H3K4me3 stimulates the V(D)J RAG complex for both nicking and hairpinning in trans in addition to tethering in cis: Implications for translocations. Mol Cell 34(5):535-544.
    • (2009) Mol Cell , vol.34 , Issue.5 , pp. 535-544
    • Shimazaki, N.1    Tsai, A.G.2    Lieber, M.R.3
  • 46
    • 79955583542 scopus 로고    scopus 로고
    • Mapping and analysis of chromatin state dynamics in nine human cell types
    • Ernst J, et al. (2011) Mapping and analysis of chromatin state dynamics in nine human cell types. Nature 473(7345):43-49.
    • (2011) Nature , vol.473 , Issue.7345 , pp. 43-49
    • Ernst, J.1
  • 47
    • 67649524640 scopus 로고    scopus 로고
    • Isolation of active regulatory elements from eukaryotic chromatin using FAIRE (Formaldehyde Assisted Isolation of Regulatory Elements)
    • Giresi PG, Lieb JD (2009) Isolation of active regulatory elements from eukaryotic chromatin using FAIRE (Formaldehyde Assisted Isolation of Regulatory Elements). Methods 48(3):233-239.
    • (2009) Methods , vol.48 , Issue.3 , pp. 233-239
    • Giresi, P.G.1    Lieb, J.D.2
  • 48
    • 80054910846 scopus 로고    scopus 로고
    • H3K4 tri-methylation provides an epigenetic signature of active enhancers
    • Pekowska A, et al. (2011) H3K4 tri-methylation provides an epigenetic signature of active enhancers. EMBO J 30(20):4198-4210.
    • (2011) EMBO J , vol.30 , Issue.20 , pp. 4198-4210
    • Pekowska, A.1
  • 49
    • 79351469446 scopus 로고    scopus 로고
    • MM-ChIP enables integrative analysis of cross-platform and between-laboratory ChIP-chip or ChIP-seq data
    • Chen Y, et al. (2011) MM-ChIP enables integrative analysis of cross-platform and between-laboratory ChIP-chip or ChIP-seq data. Genome Biol 12(2):R11.
    • (2011) Genome Biol , vol.12 , Issue.2
    • Chen, Y.1
  • 50
    • 84865761246 scopus 로고    scopus 로고
    • Modeling gene expression using chromatin features in various cellular contexts
    • Dong X, et al. (2012) Modeling gene expression using chromatin features in various cellular contexts. Genome Biol 13(9):R53.
    • (2012) Genome Biol , vol.13 , Issue.9
    • Dong, X.1
  • 52
    • 0033638506 scopus 로고    scopus 로고
    • Histone acetylation and hSWI/SNF remodeling act in concert to stimulate V(D)J cleavage of nucleosomal DNA
    • Kwon J, Morshead KB, Guyon JR, Kingston RE, Oettinger MA (2000) Histone acetylation and hSWI/SNF remodeling act in concert to stimulate V(D)J cleavage of nucleosomal DNA. Mol Cell 6(5):1037-1048.
    • (2000) Mol Cell , vol.6 , Issue.5 , pp. 1037-1048
    • Kwon, J.1    Morshead, K.B.2    Guyon, J.R.3    Kingston, R.E.4    Oettinger, M.A.5
  • 53
    • 34547112535 scopus 로고    scopus 로고
    • Essential function for SWI-SNF chromatin-remodeling complexes in the promoter-directed assembly of Tcrb genes
    • Osipovich O, et al. (2007) Essential function for SWI-SNF chromatin-remodeling complexes in the promoter-directed assembly of Tcrb genes. Nat Immunol 8(8): 809-816.
    • (2007) Nat Immunol , vol.8 , Issue.8 , pp. 809-816
    • Osipovich, O.1
  • 54
    • 0035384899 scopus 로고    scopus 로고
    • Unequal VH gene rearrangement frequency within the large VH7183 gene family is not due to recombination signal sequence variation, and mapping of the genes shows a bias of rearrangement based on chromosomal location
    • Williams GS, et al. (2001) Unequal VH gene rearrangement frequency within the large VH7183 gene family is not due to recombination signal sequence variation, and mapping of the genes shows a bias of rearrangement based on chromosomal location. J Immunol 167(1):257-263.
    • (2001) J Immunol , vol.167 , Issue.1 , pp. 257-263
    • Williams, G.S.1
  • 55
    • 84857466741 scopus 로고    scopus 로고
    • Skewed primary Igκ repertoire and V-J joining in C57BL/6 mice: Implications for recombination accessibility and receptor editing
    • Aoki-Ota M, Torkamani A, Ota T, Schork N, Nemazee D (2012) Skewed primary Igκ repertoire and V-J joining in C57BL/6 mice: Implications for recombination accessibility and receptor editing. J Immunol 188(5):2305-2315.
    • (2012) J Immunol , vol.188 , Issue.5 , pp. 2305-2315
    • Aoki-Ota, M.1    Torkamani, A.2    Ota, T.3    Schork, N.4    Nemazee, D.5
  • 56
    • 40749122641 scopus 로고    scopus 로고
    • Transcriptional repression mediated by repositioning of genes to the nuclear lamina
    • Reddy KL, Zullo JM, Bertolino E, Singh H (2008) Transcriptional repression mediated by repositioning of genes to the nuclear lamina. Nature 452(7184):243-247.
    • (2008) Nature , vol.452 , Issue.7184 , pp. 243-247
    • Reddy, K.L.1    Zullo, J.M.2    Bertolino, E.3    Singh, H.4
  • 57
    • 58149316094 scopus 로고    scopus 로고
    • IMGT, the international ImMunoGeneTics information system
    • Lefranc MP, et al. (2009) IMGT, the international ImMunoGeneTics information system. Nucleic Acids Res 37(Database issue):D1006-D1012.
    • (2009) Nucleic Acids Res , vol.37 , Issue.DATABASE ISSUE
    • Lefranc, M.P.1
  • 58
    • 34548565667 scopus 로고    scopus 로고
    • Quantitative analysis of chromosome conformation capture assays (3C-qPCR)
    • Hagège H, et al. (2007) Quantitative analysis of chromosome conformation capture assays (3C-qPCR). Nat Protoc 2(7):1722-1733.
    • (2007) Nat Protoc , vol.2 , Issue.7 , pp. 1722-1733
    • Hagège, H.1
  • 59
    • 79959354832 scopus 로고    scopus 로고
    • CCCTC-binding factor (CTCF) and cohesin influence the genomic architecture of the Igh locus and antisense transcription in pro-B cells
    • Degner SC, et al. (2011) CCCTC-binding factor (CTCF) and cohesin influence the genomic architecture of the Igh locus and antisense transcription in pro-B cells. Proc Natl Acad Sci USA 108(23):9566-9571.
    • (2011) Proc Natl Acad Sci USA , vol.108 , Issue.23 , pp. 9566-9571
    • Degner, S.C.1
  • 60
    • 0025177032 scopus 로고
    • Separate elements control DJ and VDJ rearrangement in a transgenic recombination substrate
    • Ferrier P, et al. (1990) Separate elements control DJ and VDJ rearrangement in a transgenic recombination substrate. EMBO J 9(1):117-125.
    • (1990) EMBO J , vol.9 , Issue.1 , pp. 117-125
    • Ferrier, P.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.