Enzymatic [4+2] Cycloadditions in the Biosynthesis of Spirotetramates and Spirotetronates

Methods in Enzymology

Volumn 575, Issue , 2016, Pages 39-63

  Pang, B ^a   Zhong, G ^a   Tang, Z ^a   Liu, W ^a,b  

^a SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY   (China)

^b Huzhou Center of Bio Synthetic Innovation   (China)

Author keywords

Dialkyldecalin synthase; Diels Alder reaction; Spiroconjugate synthase; Spiroketal cyclase; Spirotetramate; Spirotetronate; 4+2 Cycloaddition

Indexed keywords

ACYL CARRIER PROTEIN; ACYLTRANSFERASE; GENOMIC DNA; HYDROLYASE; NONRIBOSOMAL PEPTIDE SYNTHETASE; POLYKETIDE SYNTHASE; SPIRO COMPOUND; SPIROTETRAMATE DERIVATIVE; SPIROTETRONATE DERIVATIVE; UNCLASSIFIED DRUG; AMINOGLYCOSIDE; CHLOROTHRICIN; FURAN DERIVATIVE; LIGASE; LYASE; MACROLIDE; PYRROINDOMYCIN A; SPIROKETAL;

ACYLATION; ADENYLATION; BACTERIUM CULTURE; BIOSYNTHESIS; CHEMICAL REACTION; CHEMICAL STRUCTURE; CRYSTAL; CYCLOADDITION; DELETION MUTANT; DIELS ALDER REACTION; ENZYME SYNTHESIS; ESCHERICHIA COLI; GENE CLUSTER; HETEROLOGOUS EXPRESSION; IN VITRO STUDY; KINETICS; LOW TEMPERATURE; NONHUMAN; STREPTOMYCES ANTIBIOTICUS; X RAY DIFFRACTION; CYCLIZATION; ENZYMOLOGY; GENETICS; METABOLISM; MULTIGENE FAMILY; STREPTOMYCES;

AMINOGLYCOSIDES; BIOSYNTHETIC PATHWAYS; CYCLIZATION; CYCLOADDITION REACTION; FURANS; LIGASES; LYASES; MACROLIDES; MULTIGENE FAMILY; SPIRO COMPOUNDS; STREPTOMYCES;

EID: 84961130056     PISSN: 00766879     EISSN: 15577988     Source Type: Book Series    
DOI: 10.1016/bs.mie.2016.02.019     Document Type: Chapter

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