메뉴 건너뛰기




Volumn 19, Issue 10, 2012, Pages 1313-1323

Quartromicin biosynthesis: Two alternative polyketide chains produced by one polyketide synthase assembly line

Author keywords

[No Author keywords available]

Indexed keywords

ANTIVIRUS AGENT; POLYKETIDE SYNTHASE; QUARTROMICIN; UNCLASSIFIED DRUG;

EID: 84868028202     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chembiol.2012.07.024     Document Type: Article
Times cited : (38)

References (48)
  • 1
    • 73449104701 scopus 로고    scopus 로고
    • Crystal structures of dehydratase domains from the curacin polyketide biosynthetic pathway
    • D.L. Akey, J.R. Razelun, J. Tehranisa, D.H. Sherman, W.H. Gerwick, and J.L. Smith Crystal structures of dehydratase domains from the curacin polyketide biosynthetic pathway Structure 18 2010 94 105
    • (2010) Structure , vol.18 , pp. 94-105
    • Akey, D.L.1    Razelun, J.R.2    Tehranisa, J.3    Sherman, D.H.4    Gerwick, W.H.5    Smith, J.L.6
  • 2
    • 20444455807 scopus 로고    scopus 로고
    • Biochemical investigation of pikromycin biosynthesis employing native penta- and hexaketide chain elongation intermediates
    • DOI 10.1021/ja042592h
    • C.C. Aldrich, B.J. Beck, R.A. Fecik, and D.H. Sherman Biochemical investigation of pikromycin biosynthesis employing native penta- and hexaketide chain elongation intermediates J. Am. Chem. Soc. 127 2005 8441 8452 (Pubitemid 40828160)
    • (2005) Journal of the American Chemical Society , vol.127 , Issue.23 , pp. 8441-8452
    • Aldrich, C.C.1    Beck, B.J.2    Fecik, R.A.3    Sherman, D.H.4
  • 3
    • 0025153855 scopus 로고
    • MM46115, A new antiviral antibiotic from Actinomadura pelletieri. Characteristics of the producing cultures, fermentation, isolation, physico-chemical and biological properties
    • R.J. Ashton, M.D. Kenig, K. Luk, D.N. Planterose, and G. Scott-Wood MM 46115, a new antiviral antibiotic from Actinomadura pelletieri. Characteristics of the producing cultures, fermentation, isolation, physico-chemical and biological properties J. Antibiot. 43 1990 1387 1393 (Pubitemid 20378496)
    • (1990) Journal of Antibiotics , vol.43 , Issue.11 , pp. 1387-1393
    • Ashton, R.J.1    Kenig, M.D.2    Luk, K.3    Planterose, D.N.4    Scott-Wood, G.5
  • 5
    • 0036015840 scopus 로고    scopus 로고
    • The hidden steps of domain skipping: Macrolactone ring size determination in the pikromycin modular polyketide synthase
    • DOI 10.1016/S1074-5521(02)00146-1, PII S1074552102001461
    • B.J. Beck, Y.J. Yoon, K.A. Reynolds, and D.H. Sherman The hidden steps of domain skipping: macrolactone ring size determination in the pikromycin modular polyketide synthase Chem. Biol. 9 2002 575 583 (Pubitemid 34593038)
    • (2002) Chemistry and Biology , vol.9 , Issue.5 , pp. 575-583
    • Beck, B.J.1    Yoon, Y.J.2    Reynolds, K.A.3    Sherman, D.H.4
  • 10
    • 14844310181 scopus 로고    scopus 로고
    • A gene cluster for the fatty acid catabolism from Pseudonocardia autotrophica BCRC12444
    • DOI 10.1016/j.bbrc.2005.02.052
    • C.-H. Chen, J.-C. Cheng, Y.-C. Cho, and W.-H. Hsu A gene cluster for the fatty acid catabolism from Pseudonocardia autotrophica BCRC12444 Biochem. Biophys. Res. Commun. 329 2005 863 868 (Pubitemid 40341357)
    • (2005) Biochemical and Biophysical Research Communications , vol.329 , Issue.3 , pp. 863-868
    • Chen, C.-H.1    Cheng, J.-C.2    Cho, Y.-C.3    Hsu, W.-H.4
  • 11
    • 33644924869 scopus 로고    scopus 로고
    • Deciphering the biosynthetic codes for the potent anti-SARS-CoV cyclodepsipeptide valinomycin in Streptomyces tsusimaensis ATCC 15141
    • Y.-Q. Cheng Deciphering the biosynthetic codes for the potent anti-SARS-CoV cyclodepsipeptide valinomycin in Streptomyces tsusimaensis ATCC 15141 ChemBioChem 7 2006 471 477
    • (2006) ChemBioChem , vol.7 , pp. 471-477
    • Cheng, Y.-Q.1
  • 12
    • 79954622948 scopus 로고    scopus 로고
    • Molecular basis of elansolid biosynthesis: Evidence for an unprecedented quinone methide initiated intramolecular Diels-Alder cycloaddition/ macrolactonization
    • R. Dehn, Y. Katsuyama, A. Weber, K. Gerth, R. Jansen, H. Steinmetz, G. Höfle, R. Müller, and A. Kirschning Molecular basis of elansolid biosynthesis: evidence for an unprecedented quinone methide initiated intramolecular Diels-Alder cycloaddition/macrolactonization Angew. Chem. Int. Ed. Engl. 50 2011 3882 3887
    • (2011) Angew. Chem. Int. Ed. Engl. , vol.50 , pp. 3882-3887
    • Dehn, R.1    Katsuyama, Y.2    Weber, A.3    Gerth, K.4    Jansen, R.5    Steinmetz, H.6    Höfle, G.7    Müller, R.8    Kirschning, A.9
  • 13
    • 46649112563 scopus 로고    scopus 로고
    • Analysis of the tetronomycin gene cluster: Insights into the biosynthesis of a polyether tetronate antibiotic
    • Y. Demydchuk, Y. Sun, H. Hong, J. Staunton, J.B. Spencer, and P.F. Leadlay Analysis of the tetronomycin gene cluster: insights into the biosynthesis of a polyether tetronate antibiotic ChemBioChem 9 2008 1136 1145
    • (2008) ChemBioChem , vol.9 , pp. 1136-1145
    • Demydchuk, Y.1    Sun, Y.2    Hong, H.3    Staunton, J.4    Spencer, J.B.5    Leadlay, P.F.6
  • 14
    • 50249101630 scopus 로고    scopus 로고
    • Cloning and characterization of the tetrocarcin A gene cluster from Micromonospora chalcea NRRL 11289 reveals a highly conserved strategy for tetronate biosynthesis in spirotetronate antibiotics
    • J. Fang, Y. Zhang, L. Huang, X. Jia, Q. Zhang, X. Zhang, G.-L. Tang, and W. Liu Cloning and characterization of the tetrocarcin A gene cluster from Micromonospora chalcea NRRL 11289 reveals a highly conserved strategy for tetronate biosynthesis in spirotetronate antibiotics J. Bacteriol. 190 2008 6014 6025
    • (2008) J. Bacteriol. , vol.190 , pp. 6014-6025
    • Fang, J.1    Zhang, Y.2    Huang, L.3    Jia, X.4    Zhang, Q.5    Zhang, X.6    Tang, G.-L.7    Liu, W.8
  • 16
    • 14944360652 scopus 로고    scopus 로고
    • Macrophomate synthase: QM/MM simulations address the Diels-Alder versus Michael-Aldol reaction mechanism
    • DOI 10.1021/ja043905b
    • C.R.W. Guimarães, M. Udier-Blagović, and W.L. Jorgensen Macrophomate synthase: QM/MM simulations address the Diels-Alder versus Michael-Aldol reaction mechanism J. Am. Chem. Soc. 127 2005 3577 3588 (Pubitemid 40365296)
    • (2005) Journal of the American Chemical Society , vol.127 , Issue.10 , pp. 3577-3588
    • Guimaraes, C.R.W.1    Udier-Blagovic, M.2    Jorgensen, W.L.3
  • 17
    • 33745184421 scopus 로고    scopus 로고
    • Genetic characterization of the chlorothricin gene cluster as a model for spirotetronate antibiotic biosynthesis
    • X.-Y. Jia, Z.-H. Tian, L. Shao, X.-D. Qu, Q.-F. Zhao, J. Tang, G.-L. Tang, and W. Liu Genetic characterization of the chlorothricin gene cluster as a model for spirotetronate antibiotic biosynthesis Chem. Biol. 13 2006 575 585
    • (2006) Chem. Biol. , vol.13 , pp. 575-585
    • Jia, X.-Y.1    Tian, Z.-H.2    Shao, L.3    Qu, X.-D.4    Zhao, Q.-F.5    Tang, J.6    Tang, G.-L.7    Liu, W.8
  • 18
    • 0026529387 scopus 로고
    • New cholesterol biosynthesis inhibitors MC-031 (O-demethylchlorothricin), -032 (O-demethylhydroxychlorothricin), -033 and -034
    • A. Kawashima, Y. Nakamura, Y. Ohta, T. Akama, M. Yamagishi, and K. Hanada New cholesterol biosynthesis inhibitors MC-031 (O-demethylchlorothricin), -032 (O-demethylhydroxychlorothricin), -033 and -034 J. Antibiot. 45 1992 207 212
    • (1992) J. Antibiot. , vol.45 , pp. 207-212
    • Kawashima, A.1    Nakamura, Y.2    Ohta, Y.3    Akama, T.4    Yamagishi, M.5    Hanada, K.6
  • 19
    • 77953375007 scopus 로고    scopus 로고
    • Solanapyrone synthase, a possible Diels-Alderase and iterative type i polyketide synthase encoded in a biosynthetic gene cluster from Alternaria solani
    • K. Kasahara, T. Miyamoto, T. Fujimoto, H. Oguri, T. Tokiwano, H. Oikawa, Y. Ebizuka, and I. Fujii Solanapyrone synthase, a possible Diels-Alderase and iterative type I polyketide synthase encoded in a biosynthetic gene cluster from Alternaria solani ChemBioChem 11 2010 1245 1252
    • (2010) ChemBioChem , vol.11 , pp. 1245-1252
    • Kasahara, K.1    Miyamoto, T.2    Fujimoto, T.3    Oguri, H.4    Tokiwano, T.5    Oikawa, H.6    Ebizuka, Y.7    Fujii, I.8
  • 20
    • 34547945950 scopus 로고    scopus 로고
    • A Tylosin Ketoreductase Reveals How Chirality Is Determined in Polyketides
    • DOI 10.1016/j.chembiol.2007.07.009, PII S1074552107002487
    • A.T. Keatinge-Clay A tylosin ketoreductase reveals how chirality is determined in polyketides Chem. Biol. 14 2007 898 908 (Pubitemid 47268779)
    • (2007) Chemistry and Biology , vol.14 , Issue.8 , pp. 898-908
    • Keatinge-Clay, A.T.1
  • 21
    • 57049138419 scopus 로고    scopus 로고
    • Intramolecular cyclizations of polyketide biosynthesis: Mining for a "diels-Alderase"?
    • W.L. Kelly Intramolecular cyclizations of polyketide biosynthesis: mining for a "Diels-Alderase"? Org. Biomol. Chem. 6 2008 4483 4493
    • (2008) Org. Biomol. Chem. , vol.6 , pp. 4483-4493
    • Kelly, W.L.1
  • 22
    • 79955642774 scopus 로고    scopus 로고
    • Enzyme-catalysed [4+2] cycloaddition is a key step in the biosynthesis of spinosyn A
    • H.J. Kim, M.W. Ruszczycky, S.H. Choi, Y.-N. Liu, and H.-W. Liu Enzyme-catalysed [4+2] cycloaddition is a key step in the biosynthesis of spinosyn A Nature 473 2011 109 112
    • (2011) Nature , vol.473 , pp. 109-112
    • Kim, H.J.1    Ruszczycky, M.W.2    Choi, S.H.3    Liu, Y.-N.4    Liu, H.-W.5
  • 23
    • 0037423499 scopus 로고    scopus 로고
    • Enzymology of acyl chain macrocyclization in natural product biosynthesis
    • R.M. Kohli, and C.T. Walsh Enzymology of acyl chain macrocyclization in natural product biosynthesis Chem. Commun. (Camb.) 3 2003 297 307 (Pubitemid 36207689)
    • (2003) Chemical Communications , Issue.3 , pp. 297-307
    • Kohli, R.M.1    Walsh, C.T.2
  • 24
    • 0026325940 scopus 로고
    • The structures of quartromicins A1, A2, and A3: Novel macrocyclic antiviral antibiotics possessing four tetronic acid moieties
    • T. Kusumi, A. Ichikawa, H. Kakisawa, M. Tsunakawa, M. Konishi, and T. Oki The structures of quartromicins A1, A2, and A3: novel macrocyclic antiviral antibiotics possessing four tetronic acid moieties J. Am. Chem. Soc. 113 1991 8947 8948
    • (1991) J. Am. Chem. Soc. , vol.113 , pp. 8947-8948
    • Kusumi, T.1    Ichikawa, A.2    Kakisawa, H.3    Tsunakawa, M.4    Konishi, M.5    Oki, T.6
  • 25
    • 51149086592 scopus 로고    scopus 로고
    • Concise synthesis of key 3-polyenoyl-5-methylenefuran-2,4-dione putative intermediates in quartromicin biosynthesis
    • L.J. Montgomery, and G.L. Challis Concise synthesis of key 3-polyenoyl-5-methylenefuran-2,4-dione putative intermediates in quartromicin biosynthesis Synlett 2008 2164 2168
    • (2008) Synlett , pp. 2164-2168
    • Montgomery, L.J.1    Challis, G.L.2
  • 26
    • 7744235042 scopus 로고    scopus 로고
    • Loss of co-linearity by modular polyketide synthases: A mechanism for the evolution of chemical diversity
    • DOI 10.1039/b315020h
    • S.J. Moss, C.J. Martin, and B. Wilkinson Loss of co-linearity by modular polyketide synthases: a mechanism for the evolution of chemical diversity Nat. Prod. Rep. 21 2004 575 593 (Pubitemid 39459641)
    • (2004) Natural Product Reports , vol.21 , Issue.5 , pp. 575-593
    • Moss, S.J.1    Martin, C.J.2    Wilkinson, B.3
  • 27
    • 0027497834 scopus 로고
    • Tetronothiodin, a novel cholecystokinin type-B receptor antagonist produced by streptomyces sp. NR0489. II. Isolation, characterization and biological activities
    • T. Ohtsuka, H. Kotaki, N. Nakayama, Y. Itezono, N. Shimma, T. Kudoh, T. Kuwahara, M. Arisawa, K. Yokose, and H. Seto Tetronothiodin, a novel cholecystokinin type-B receptor antagonist produced by Streptomyces sp. NR0489. II. Isolation, characterization and biological activities J. Antibiot. 46 1993 11 17 (Pubitemid 23075312)
    • (1993) Journal of Antibiotics , vol.46 , Issue.1 , pp. 11-17
    • Ohtsuka, T.1    Kotaki, H.2    Nakayama, N.3    Itezono, Y.4    Shimma, N.5    Kudoh, T.6    Kuwahara, T.7    Arisawa, M.8    Yokose, K.9    Seto, H.10
  • 28
    • 3042745794 scopus 로고    scopus 로고
    • Enzymatic catalysis of the Diels-Alder reaction in the biosynthesis of natural products
    • DOI 10.1039/b305068h
    • H. Oikawa, and T. Tokiwano Enzymatic catalysis of the Diels-Alder reaction in the biosynthesis of natural products Nat. Prod. Rep. 21 2004 321 352 (Pubitemid 38865717)
    • (2004) Natural Product Reports , vol.21 , Issue.3 , pp. 321-352
    • Oikawa, H.1    Tokiwano, T.2
  • 29
    • 0037434992 scopus 로고    scopus 로고
    • Insight into a natural Diels-Alder reaction from the structure of macrophomate synthase
    • DOI 10.1038/nature01454
    • T. Ose, K. Watanabe, T. Mie, M. Honma, H. Watanabe, M. Yao, H. Oikawa, and I. Tanaka Insight into a natural Diels-Alder reaction from the structure of macrophomate synthase Nature 422 2003 185 189 (Pubitemid 36362753)
    • (2003) Nature , vol.422 , Issue.6928 , pp. 185-189
    • Ose, T.1    Watanabe, K.2    Mie, T.3    Honma, M.4    Watanabe, H.5    Yao, M.6    Oikawa, H.7    Tanaka, I.8
  • 30
    • 0032501971 scopus 로고    scopus 로고
    • Characterization of Sfp, a Bacillus subtilis phosphopantetheinyl transferase for peptidyl carder protein domains in peptide synthetases
    • DOI 10.1021/bi9719861
    • L.E. Quadri, P.H. Weinreb, M. Lei, M.M. Nakano, P. Zuber, and C.T. Walsh Characterization of Sfp, a Bacillus subtilis phosphopantetheinyl transferase for peptidyl carrier protein domains in peptide synthetases Biochemistry 37 1998 1585 1595 (Pubitemid 28093674)
    • (1998) Biochemistry , vol.37 , Issue.6 , pp. 1585-1595
    • Quadri, L.E.N.1    Weinreb, P.H.2    Lei, M.3    Nakano, M.M.4    Zuber, P.5    Walsh, C.T.6
  • 31
    • 0035951074 scopus 로고    scopus 로고
    • Alteration of the substrate specificity of a modular polyketide synthase acyltransferase domain through site-specific mutations
    • DOI 10.1021/bi015864r
    • C.D. Reeves, S. Murli, G.W. Ashley, M. Piagentini, C.R. Hutchinson, and R. McDaniel Alteration of the substrate specificity of a modular polyketide synthase acyltransferase domain through site-specific mutations Biochemistry 40 2001 15464 15470 (Pubitemid 34015173)
    • (2001) Biochemistry , vol.40 , Issue.51 , pp. 15464-15470
    • Reeves, C.D.1    Murli, S.2    Ashley, G.W.3    Piagentini, M.4    Hutchinson, C.R.5    McDaniel, R.6
  • 35
    • 38149064397 scopus 로고    scopus 로고
    • Glyceryl-S-acyl carrier protein as an intermediate in the biosynthesis of tetronate antibiotics
    • Y. Sun, H. Hong, F. Gillies, J.B. Spencer, and P.F. Leadlay Glyceryl-S-acyl carrier protein as an intermediate in the biosynthesis of tetronate antibiotics ChemBioChem 9 2008 150 156
    • (2008) ChemBioChem , vol.9 , pp. 150-156
    • Sun, Y.1    Hong, H.2    Gillies, F.3    Spencer, J.B.4    Leadlay, P.F.5
  • 37
    • 0026460299 scopus 로고
    • Anti-human immunodeficiency virus (HIV) activity of the novel antiviral antibiotic quartromicins which enhance inhibitory effect of 3′-azido- 2′,3′-dideoxythymidine (AZT) in vitro
    • A. Tanabe-Tochikura, H. Nakashima, T. Murakami, O. Tenmyo, T. Oki, and N. Yamamoto Anti-human immunodeficiency virus (HIV) activity of the novel antiviral antibiotic quartromicins which enhance inhibitory effect of 3′-azido-2′,3′-dideoxythymidine (AZT) in vitro Antivir. Chem. Chemother. 3 1992 345 349
    • (1992) Antivir. Chem. Chemother. , vol.3 , pp. 345-349
    • Tanabe-Tochikura, A.1    Nakashima, H.2    Murakami, T.3    Tenmyo, O.4    Oki, T.5    Yamamoto, N.6
  • 38
    • 0035989968 scopus 로고    scopus 로고
    • Skipping in a hybrid polyketide synthase: Evidence for ACP-to-ACP chain transfer
    • DOI 10.1016/S1074-5521(02)00164-3, PII S1074552102001643
    • I. Thomas, C.J. Martin, C.J. Wilkinson, J. Staunton, and P.F. Leadlay Skipping in a hybrid polyketide synthase. Evidence for ACP-to-ACP chain transfer Chem. Biol. 9 2002 781 787 (Pubitemid 34861155)
    • (2002) Chemistry and Biology , vol.9 , Issue.7 , pp. 781-787
    • Thomas, I.1    Martin, C.J.2    Wilkinson, C.J.3    Staunton, J.4    Leadlay, P.F.5
  • 39
    • 0018942259 scopus 로고
    • Novel antitumor antibiotics, tetrocarcins
    • F. Tomita, T. Tamaoki, K. Shirahata, M. Kasai, M. Morimoto, S. Ohkubo, K. Mineura, and S. Ishii Novel antitumor antibiotics, tetrocarcins J. Antibiot. 33 1980 668 670 (Pubitemid 10016623)
    • (1980) Journal of Antibiotics , vol.33 , Issue.6 , pp. 668-670
    • Tomita, F.1    Tamaoki, T.2    Shirahata, K.3
  • 40
    • 80053598148 scopus 로고    scopus 로고
    • A "diels-Alderase" at last
    • C.A. Townsend A "Diels-Alderase" at last ChemBioChem 12 2011 2267 2269
    • (2011) ChemBioChem , vol.12 , pp. 2267-2269
    • Townsend, C.A.1
  • 41
    • 0026577158 scopus 로고
    • Quartromicin, a complex of novel antiviral antibiotics. I. Production, isolation, physico-chemical properties and antiviral activity
    • M. Tsunakawa, O. Tenmyo, K. Tomita, N. Naruse, C. Kotake, T. Miyaki, M. Konishi, and T. Oki Quartromicin, a complex of novel antiviral antibiotics. I. Production, isolation, physico-chemical properties and antiviral activity J. Antibiot. 45 1992 180 188
    • (1992) J. Antibiot. , vol.45 , pp. 180-188
    • Tsunakawa, M.1    Tenmyo, O.2    Tomita, K.3    Naruse, N.4    Kotake, C.5    Miyaki, T.6    Konishi, M.7    Oki, T.8
  • 42
    • 0019799763 scopus 로고
    • Kijanimicin (Sch 25663), a novel antibiotic produced by Actinomadura kijaniata SCC 1256. Fermentation, isolation, characterization and biological properties
    • J.A. Waitz, A.C. Horan, M. Kalyanpur, B.K. Lee, D. Loebenberg, J.A. Marquez, G. Miller, and M.G. Patel Kijanimicin (Sch 25663), a novel antibiotic produced by Actinomadura kijaniata SCC 1256. Fermentation, isolation, characterization and biological properties J. Antibiot. 34 1981 1101 1106 (Pubitemid 12174605)
    • (1981) Journal of Antibiotics , vol.34 , Issue.9 , pp. 1101-1106
    • Waitz, J.A.1    Horan, A.C.2    Kalyanpur, M.3
  • 44
    • 33746320424 scopus 로고    scopus 로고
    • Nonribosomal peptide biosynthesis: Point mutations and module skipping lead to chemical diversity
    • DOI 10.1002/anie.200503737
    • S.C. Wenzel, P. Meiser, T.M. Binz, T. Mahmud, and R. Müller Nonribosomal peptide biosynthesis: point mutations and module skipping lead to chemical diversity Angew. Chem. Int. Ed. Engl. 45 2006 2296 2301 (Pubitemid 44105167)
    • (2006) Angewandte Chemie - International Edition , vol.45 , Issue.14 , pp. 2296-2301
    • Wenzel, S.C.1    Meiser, P.2    Binz, T.M.3    Mahmud, T.4    Muller, R.5
  • 45
    • 59449083487 scopus 로고    scopus 로고
    • A type I/type III polyketide synthase hybrid biosynthetic pathway for the structurally unique ansa compound kendomycin
    • S.C. Wenzel, H.B. Bode, I. Kochems, and R. Müller A type I/type III polyketide synthase hybrid biosynthetic pathway for the structurally unique ansa compound kendomycin ChemBioChem 9 2008 2711 2721
    • (2008) ChemBioChem , vol.9 , pp. 2711-2721
    • Wenzel, S.C.1    Bode, H.B.2    Kochems, I.3    Müller, R.4
  • 46
    • 0034598743 scopus 로고    scopus 로고
    • Alternative modular polyketide synthase expression controls macrolactone structure
    • DOI 10.1038/35000624
    • Y. Xue, and D.H. Sherman Alternative modular polyketide synthase expression controls macrolactone structure Nature 403 2000 571 575 (Pubitemid 30082206)
    • (2000) Nature , vol.403 , Issue.6769 , pp. 571-575
    • Xue, Y.1    Sherman, D.H.2
  • 47
    • 36749055680 scopus 로고    scopus 로고
    • Elucidation of the kijanimicin gene cluster: Insights into the biosynthesis of spirotetronate antibiotics and nitrosugars
    • DOI 10.1021/ja0744854
    • H. Zhang, J.A. White-Phillip, C.E. Melançon 3rd, H.-J. Kwon, W.L. Yu, and H.-W. Liu Elucidation of the kijanimicin gene cluster: insights into the biosynthesis of spirotetronate antibiotics and nitrosugars J. Am. Chem. Soc. 129 2007 14670 14683 (Pubitemid 350207880)
    • (2007) Journal of the American Chemical Society , vol.129 , Issue.47 , pp. 14670-14683
    • Zhang, H.1    White-Phillip, J.A.2    Melancon III, C.E.3    Kwon, H.-J.4    Yu, W.-L.5    Liu, H.-W.6
  • 48
    • 77957601090 scopus 로고    scopus 로고
    • Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism
    • W. Zhao, Y. Zhong, H. Yuan, J. Wang, H. Zheng, Y. Wang, X. Cen, F. Xu, J. Bai, and X. Han Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism Cell Res. 20 2010 1096 1108
    • (2010) Cell Res. , vol.20 , pp. 1096-1108
    • Zhao, W.1    Zhong, Y.2    Yuan, H.3    Wang, J.4    Zheng, H.5    Wang, Y.6    Cen, X.7    Xu, F.8    Bai, J.9    Han, X.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.