Mechanistic insights on riboflavin synthase inspired by selective binding of the 6,7-dimethyl-8-ribityllumazine exomethylene anion

Journal of the American Chemical Society

Volumn 132, Issue 9, 2010, Pages 2983-2990

  Kim, Ryu Ryun ^a   Illarionov, Boris ^b   Joshi, Monika ^c   Cushman, Mark ^d   Lee, Chan Yong ^e   Eisenreich, Wolfgang ^c   Fischer, Markus ^a   Bacher, Adelbert ^b,c  

^a UNIVERSITY OF HAMBURG   (Germany)

^b Ikosatec GmbH   (Germany)

^c TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^d PURDUE UNIVERSITY   (United States)

^e Chungnam National University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

[4 + 2] CYCLOADDITION; AQUEOUS SOLUTIONS; COMPLEX ANIONS; EXPERIMENTAL DATA; HYDRIDE TRANSFERS; N-TERMINAL DOMAINS; NOVEL CONCEPT; REACTION SEQUENCES; REACTION STEPS; SELECTIVE BINDING; SYNTHASES;

ESCHERICHIA COLI; MOLECULES;

NEGATIVE IONS;

ANION; CARBENOID; LUMAZINE; NUCLEOPHILE; RIBOFLAVIN SYNTHASE;

AMINO TERMINAL SEQUENCE; AQUEOUS SOLUTION; ARTICLE; BINDING AFFINITY; CYCLOADDITION; ENZYME MECHANISM; ENZYME STRUCTURE; ESCHERICHIA COLI; HYPOTHESIS; MUTAGENESIS; NONHUMAN;

ANIONS; BINDING SITES; BIOCATALYSIS; MOLECULAR STRUCTURE; PTERIDINES; RIBOFLAVIN; RIBOFLAVIN SYNTHASE; STEREOISOMERISM; URIDINE;

EID: 77949358978     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja908395r     Document Type: Article

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