-
1
-
-
34547860028
-
Differences in breast carcinoma characteristics in newly diagnosed African-American and Caucasian patients: a single-institution compilation compared with the National Cancer Institute's Surveillance, Epidemiology, and End Results database
-
Morris GJ, Naidu S, Topham AK, Guiles F, Xu Y, et al. (2007) Differences in breast carcinoma characteristics in newly diagnosed African-American and Caucasian patients: a single-institution compilation compared with the National Cancer Institute's Surveillance, Epidemiology, and End Results database. Cancer 110: 876-884.
-
(2007)
Cancer
, vol.110
, pp. 876-884
-
-
Morris, G.J.1
Naidu, S.2
Topham, A.K.3
Guiles, F.4
Xu, Y.5
-
2
-
-
68149163711
-
Triple-negative breast cancers are increased in black women regardless of age or body mass index
-
Stead LA, Lash TL, Sobieraj JE, Chi DD, Westrup JL, et al. (2009) Triple-negative breast cancers are increased in black women regardless of age or body mass index. Breast Cancer Res 11: R18.
-
(2009)
Breast Cancer Res
, vol.11
-
-
Stead, L.A.1
Lash, T.L.2
Sobieraj, J.E.3
Chi, D.D.4
Westrup, J.L.5
-
3
-
-
34247381115
-
Locoregional relapse and distant metastasis in conservatively managed triple negative early-stage breast cancer
-
Haffty BG, Yang Q, Reiss M, Kearney T, Higgins SA, et al. (2006) Locoregional relapse and distant metastasis in conservatively managed triple negative early-stage breast cancer. J Clin Oncol 24: 5652-5657.
-
(2006)
J Clin Oncol
, vol.24
, pp. 5652-5657
-
-
Haffty, B.G.1
Yang, Q.2
Reiss, M.3
Kearney, T.4
Higgins, S.A.5
-
4
-
-
34547661993
-
Triple-negative breast cancer: clinical features and patterns of recurrence
-
Dent R, Trudeau M, Pritchard KI, Hanna WM, Kahn HK, et al. (2007) Triple-negative breast cancer: clinical features and patterns of recurrence. Clin Cancer Res 13: 4429-4434.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 4429-4434
-
-
Dent, R.1
Trudeau, M.2
Pritchard, K.I.3
Hanna, W.M.4
Kahn, H.K.5
-
5
-
-
0031903646
-
Phase II study of receptor-enhanced chemosensitivity using recombinant humanized anti-p185HER2/neu monoclonal antibody plus cisplatin in patients with HER2/neu-overexpressing metastatic breast cancer refractory to chemotherapy treatment
-
Pegram MD, Lipton A, Hayes DF, Weber BL, Baselga JM, et al. (1998) Phase II study of receptor-enhanced chemosensitivity using recombinant humanized anti-p185HER2/neu monoclonal antibody plus cisplatin in patients with HER2/neu-overexpressing metastatic breast cancer refractory to chemotherapy treatment. J Clin Oncol 16: 2659-2671.
-
(1998)
J Clin Oncol
, vol.16
, pp. 2659-2671
-
-
Pegram, M.D.1
Lipton, A.2
Hayes, D.F.3
Weber, B.L.4
Baselga, J.M.5
-
6
-
-
33847063053
-
The triple negative paradox: primary tumor chemosensitivity of breast cancer subtypes
-
Carey LA, Dees EC, Sawyer L, Gatti L, Moore DT, et al. (2007) The triple negative paradox: primary tumor chemosensitivity of breast cancer subtypes. Clin Cancer Res 13: 2329-2334.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 2329-2334
-
-
Carey, L.A.1
Dees, E.C.2
Sawyer, L.3
Gatti, L.4
Moore, D.T.5
-
7
-
-
33847136743
-
Triple-negative breast cancer: therapeutic options
-
Cleator S, Heller W, Coombes RC, (2007) Triple-negative breast cancer: therapeutic options. Lancet Oncol 8: 235-244.
-
(2007)
Lancet Oncol
, vol.8
, pp. 235-244
-
-
Cleator, S.1
Heller, W.2
Coombes, R.C.3
-
8
-
-
33947225176
-
Identification of candidate molecular markers predicting sensitivity in solid tumors to dasatinib: rationale for patient selection
-
Huang F, Reeves K, Han X, Fairchild C, Platero S, et al. (2007) Identification of candidate molecular markers predicting sensitivity in solid tumors to dasatinib: rationale for patient selection. Cancer Res 67: 2226-2238.
-
(2007)
Cancer Res
, vol.67
, pp. 2226-2238
-
-
Huang, F.1
Reeves, K.2
Han, X.3
Fairchild, C.4
Platero, S.5
-
9
-
-
31044447246
-
Role of c-Src and focal adhesion kinase in progression and metastasis of estrogen receptor-positive breast cancer
-
Planas-Silva MD, Bruggeman RD, Grenko RT, Stanley Smith J, (2006) Role of c-Src and focal adhesion kinase in progression and metastasis of estrogen receptor-positive breast cancer. Biochem Biophys Res Commun 341: 73-81.
-
(2006)
Biochem Biophys Res Commun
, vol.341
, pp. 73-81
-
-
Planas-Silva, M.D.1
Bruggeman, R.D.2
Grenko, R.T.3
Stanley Smith, J.4
-
10
-
-
33846235881
-
Cooperative action of tamoxifen and c-Src inhibition in preventing the growth of estrogen receptor-positive human breast cancer cells
-
Herynk MH, Beyer AR, Cui Y, Weiss H, Anderson E, et al. (2006) Cooperative action of tamoxifen and c-Src inhibition in preventing the growth of estrogen receptor-positive human breast cancer cells. Mol Cancer Ther 5: 3023-3031.
-
(2006)
Mol Cancer Ther
, vol.5
, pp. 3023-3031
-
-
Herynk, M.H.1
Beyer, A.R.2
Cui, Y.3
Weiss, H.4
Anderson, E.5
-
11
-
-
7944237784
-
The interplay between Src family kinases and receptor tyrosine kinases
-
Bromann PA, Korkaya H, Courtneidge SA, (2004) The interplay between Src family kinases and receptor tyrosine kinases. Oncogene 23: 7957-7968.
-
(2004)
Oncogene
, vol.23
, pp. 7957-7968
-
-
Bromann, P.A.1
Korkaya, H.2
Courtneidge, S.A.3
-
12
-
-
0027954475
-
Activation of the c-Src tyrosine kinase is required for the induction of mammary tumors in transgenic mice
-
Guy CT, Muthuswamy SK, Cardiff RD, Soriano P, Muller WJ, (1994) Activation of the c-Src tyrosine kinase is required for the induction of mammary tumors in transgenic mice. Genes Dev 8: 23-32.
-
(1994)
Genes Dev
, vol.8
, pp. 23-32
-
-
Guy, C.T.1
Muthuswamy, S.K.2
Cardiff, R.D.3
Soriano, P.4
Muller, W.J.5
-
13
-
-
33745402375
-
Elevated Src activity promotes cellular invasion and motility in tamoxifen resistant breast cancer cells
-
Hiscox S, Morgan L, Green TP, Barrow D, Gee J, et al. (2006) Elevated Src activity promotes cellular invasion and motility in tamoxifen resistant breast cancer cells. Breast Cancer Res Treat 97: 263-274.
-
(2006)
Breast Cancer Res Treat
, vol.97
, pp. 263-274
-
-
Hiscox, S.1
Morgan, L.2
Green, T.P.3
Barrow, D.4
Gee, J.5
-
14
-
-
0030482560
-
Translocation of Src kinase to the cell periphery is mediated by the actin cytoskeleton under the control of the Rho family of small G proteins
-
Fincham VJ, Unlu M, Brunton VG, Pitts JD, Wyke JA, et al. (1996) Translocation of Src kinase to the cell periphery is mediated by the actin cytoskeleton under the control of the Rho family of small G proteins. J Cell Biol 135: 1551-1564.
-
(1996)
J Cell Biol
, vol.135
, pp. 1551-1564
-
-
Fincham, V.J.1
Unlu, M.2
Brunton, V.G.3
Pitts, J.D.4
Wyke, J.A.5
-
15
-
-
2942618768
-
A renaissance for SRC
-
Yeatman TJ, (2004) A renaissance for SRC. Nat Rev Cancer 4: 470-480.
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 470-480
-
-
Yeatman, T.J.1
-
16
-
-
38349014380
-
Src family kinases: regulation of their activities, levels and identification of new pathways
-
Ingley E, (2008) Src family kinases: regulation of their activities, levels and identification of new pathways. Biochim Biophys Acta 1784: 56-65.
-
(2008)
Biochim Biophys Acta
, vol.1784
, pp. 56-65
-
-
Ingley, E.1
-
17
-
-
79955727135
-
The dual kinase complex FAK-Src as a promising therapeutic target in cancer
-
Bolos V, Gasent JM, Lopez-Tarruella S, Grande E, (2010) The dual kinase complex FAK-Src as a promising therapeutic target in cancer. Onco Targets Ther 3: 83-97.
-
(2010)
Onco Targets Ther
, vol.3
, pp. 83-97
-
-
Bolos, V.1
Gasent, J.M.2
Lopez-Tarruella, S.3
Grande, E.4
-
18
-
-
0037150728
-
Src in cancer: deregulation and consequences for cell behaviour
-
Frame MC, (2002) Src in cancer: deregulation and consequences for cell behaviour. Biochim Biophys Acta 1602: 114-130.
-
(2002)
Biochim Biophys Acta
, vol.1602
, pp. 114-130
-
-
Frame, M.C.1
-
19
-
-
0242267055
-
Src mediates prolactin-dependent proliferation of T47D and MCF7 cells via the activation of focal adhesion kinase/Erk1/2 and phosphatidylinositol 3-kinase pathways
-
Acosta JJ, Munoz RM, Gonzalez L, Subtil-Rodriguez A, Dominguez-Caceres MA, et al. (2003) Src mediates prolactin-dependent proliferation of T47D and MCF7 cells via the activation of focal adhesion kinase/Erk1/2 and phosphatidylinositol 3-kinase pathways. Mol Endocrinol 17: 2268-2282.
-
(2003)
Mol Endocrinol
, vol.17
, pp. 2268-2282
-
-
Acosta, J.J.1
Munoz, R.M.2
Gonzalez, L.3
Subtil-Rodriguez, A.4
Dominguez-Caceres, M.A.5
-
20
-
-
33746342801
-
Role of c-Src in human MCF7 breast cancer cell tumorigenesis
-
Gonzalez L, Agullo-Ortuno MT, Garcia-Martinez JM, Calcabrini A, Gamallo C, et al. (2006) Role of c-Src in human MCF7 breast cancer cell tumorigenesis. J Biol Chem 281: 20851-20864.
-
(2006)
J Biol Chem
, vol.281
, pp. 20851-20864
-
-
Gonzalez, L.1
Agullo-Ortuno, M.T.2
Garcia-Martinez, J.M.3
Calcabrini, A.4
Gamallo, C.5
-
21
-
-
33744936606
-
Upregulation and activation of PKC alpha by ErbB2 through Src promotes breast cancer cell invasion that can be blocked by combined treatment with PKC alpha and Src inhibitors
-
Tan M, Li P, Sun M, Yin G, Yu D, (2006) Upregulation and activation of PKC alpha by ErbB2 through Src promotes breast cancer cell invasion that can be blocked by combined treatment with PKC alpha and Src inhibitors. Oncogene 25: 3286-3295.
-
(2006)
Oncogene
, vol.25
, pp. 3286-3295
-
-
Tan, M.1
Li, P.2
Sun, M.3
Yin, G.4
Yu, D.5
-
22
-
-
48749118203
-
Targeting Src in breast cancer
-
Finn RS, (2008) Targeting Src in breast cancer. Ann Oncol 19: 1379-1386.
-
(2008)
Ann Oncol
, vol.19
, pp. 1379-1386
-
-
Finn, R.S.1
-
23
-
-
79960015997
-
Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies
-
Lehmann BD, Bauer JA, Chen X, Sanders ME, Chakravarthy AB, et al. (2011) Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies. J Clin Invest 121: 2750-2767.
-
(2011)
J Clin Invest
, vol.121
, pp. 2750-2767
-
-
Lehmann, B.D.1
Bauer, J.A.2
Chen, X.3
Sanders, M.E.4
Chakravarthy, A.B.5
-
24
-
-
0030474489
-
c-Src protein expression is increased in human breast cancer. An immunohistochemical and biochemical analysis
-
Verbeek BS, Vroom TM, Adriaansen-Slot SS, Ottenhoff-Kalff AE, Geertzema JG, et al. (1996) c-Src protein expression is increased in human breast cancer. An immunohistochemical and biochemical analysis. J Pathol 180: 383-388.
-
(1996)
J Pathol
, vol.180
, pp. 383-388
-
-
Verbeek, B.S.1
Vroom, T.M.2
Adriaansen-Slot, S.S.3
Ottenhoff-Kalff, A.E.4
Geertzema, J.G.5
-
25
-
-
0034741233
-
Elevated activity and expression of Src-family kinases in human breast carcinoma tissue versus matched non-tumor tissue
-
Reissig D, Clement J, Sanger J, Berndt A, Kosmehl H, et al. (2001) Elevated activity and expression of Src-family kinases in human breast carcinoma tissue versus matched non-tumor tissue. J Cancer Res Clin Oncol 127: 226-230.
-
(2001)
J Cancer Res Clin Oncol
, vol.127
, pp. 226-230
-
-
Reissig, D.1
Clement, J.2
Sanger, J.3
Berndt, A.4
Kosmehl, H.5
-
26
-
-
56749185425
-
Phosphorylated c-Src in the nucleus is associated with improved patient outcome in ER-positive breast cancer
-
Campbell EJ, McDuff E, Tatarov O, Tovey S, Brunton V, et al. (2008) Phosphorylated c-Src in the nucleus is associated with improved patient outcome in ER-positive breast cancer. Br J Cancer 99: 1769-1774.
-
(2008)
Br J Cancer
, vol.99
, pp. 1769-1774
-
-
Campbell, E.J.1
McDuff, E.2
Tatarov, O.3
Tovey, S.4
Brunton, V.5
-
27
-
-
73549112454
-
Is expression or activation of Src kinase associated with cancer-specific survival in ER-, PR- and HER2-negative breast cancer patients?
-
Elsberger B, Tan BA, Mitchell TJ, Brown SB, Mallon EA, et al. (2009) Is expression or activation of Src kinase associated with cancer-specific survival in ER-, PR- and HER2-negative breast cancer patients? Am J Pathol 175: 1389-1397.
-
(2009)
Am J Pathol
, vol.175
, pp. 1389-1397
-
-
Elsberger, B.1
Tan, B.A.2
Mitchell, T.J.3
Brown, S.B.4
Mallon, E.A.5
-
28
-
-
80052505248
-
Src: a potential target for the treatment of triple-negative breast cancer
-
Tryfonopoulos D, Walsh S, Collins DM, Flanagan L, Quinn C, et al. (2011) Src: a potential target for the treatment of triple-negative breast cancer. Ann Oncol.
-
(2011)
Ann Oncol
-
-
Tryfonopoulos, D.1
Walsh, S.2
Collins, D.M.3
Flanagan, L.4
Quinn, C.5
-
29
-
-
77956430031
-
Breast cancer patients' clinical outcome measures are associated with Src kinase family member expression
-
Elsberger B, Fullerton R, Zino S, Jordan F, Mitchell TJ, et al. (2010) Breast cancer patients' clinical outcome measures are associated with Src kinase family member expression. Br J Cancer 103: 899-909.
-
(2010)
Br J Cancer
, vol.103
, pp. 899-909
-
-
Elsberger, B.1
Fullerton, R.2
Zino, S.3
Jordan, F.4
Mitchell, T.J.5
-
30
-
-
79959362334
-
Clinicopathological significance of Y416Src and Y527Src expression in breast cancer
-
Kanomata N, Kurebayashi J, Kozuka Y, Sonoo H, Moriya T, (2011) Clinicopathological significance of Y416Src and Y527Src expression in breast cancer. J Clin Pathol 64: 578-586.
-
(2011)
J Clin Pathol
, vol.64
, pp. 578-586
-
-
Kanomata, N.1
Kurebayashi, J.2
Kozuka, Y.3
Sonoo, H.4
Moriya, T.5
-
31
-
-
0034099236
-
Elevated levels of p66 Shc are found in breast cancer cell lines and primary tumors with high metastatic potential
-
Jackson JG, Yoneda T, Clark GM, Yee D, (2000) Elevated levels of p66 Shc are found in breast cancer cell lines and primary tumors with high metastatic potential. Clin Cancer Res 6: 1135-1139.
-
(2000)
Clin Cancer Res
, vol.6
, pp. 1135-1139
-
-
Jackson, J.G.1
Yoneda, T.2
Clark, G.M.3
Yee, D.4
-
32
-
-
0035826165
-
Alterations in the focal adhesion kinase/Src signal transduction pathway correlate with increased migratory capacity of prostate carcinoma cells
-
Slack JK, Adams RB, Rovin JD, Bissonette EA, Stoker CE, et al. (2001) Alterations in the focal adhesion kinase/Src signal transduction pathway correlate with increased migratory capacity of prostate carcinoma cells. Oncogene 20: 1152-1163.
-
(2001)
Oncogene
, vol.20
, pp. 1152-1163
-
-
Slack, J.K.1
Adams, R.B.2
Rovin, J.D.3
Bissonette, E.A.4
Stoker, C.E.5
-
33
-
-
6844259884
-
Activation of c-Src by receptor tyrosine kinases in human colon cancer cells with high metastatic potential
-
Mao W, Irby R, Coppola D, Fu L, Wloch M, et al. (1997) Activation of c-Src by receptor tyrosine kinases in human colon cancer cells with high metastatic potential. Oncogene 15: 3083-3090.
-
(1997)
Oncogene
, vol.15
, pp. 3083-3090
-
-
Mao, W.1
Irby, R.2
Coppola, D.3
Fu, L.4
Wloch, M.5
-
34
-
-
79958083207
-
Search for new treatments intensifies for triple-negative breast cancer
-
Brower V, (2009) Search for new treatments intensifies for triple-negative breast cancer. J Natl Cancer Inst 101: 1536-1537.
-
(2009)
J Natl Cancer Inst
, vol.101
, pp. 1536-1537
-
-
Brower, V.1
-
35
-
-
78649663247
-
Triple-negative breast cancer: disease entity or title of convenience?
-
Carey L, Winer E, Viale G, Cameron D, Gianni L, (2010) Triple-negative breast cancer: disease entity or title of convenience? Nat Rev Clin Oncol 7: 683-692.
-
(2010)
Nat Rev Clin Oncol
, vol.7
, pp. 683-692
-
-
Carey, L.1
Winer, E.2
Viale, G.3
Cameron, D.4
Gianni, L.5
-
36
-
-
84855748821
-
Phase II Trial of Saracatinib (AZD0530), an Oral SRC-inhibitor for the Treatment of Patients with Hormone Receptor-negative Metastatic Breast Cancer
-
Gucalp A, Sparano JA, Caravelli J, Santamauro J, Patil S, et al. (2011) Phase II Trial of Saracatinib (AZD0530), an Oral SRC-inhibitor for the Treatment of Patients with Hormone Receptor-negative Metastatic Breast Cancer. Clin Breast Cancer.
-
(2011)
Clin Breast Cancer
-
-
Gucalp, A.1
Sparano, J.A.2
Caravelli, J.3
Santamauro, J.4
Patil, S.5
-
37
-
-
75149144814
-
Increased levels of active c-Src distinguish invasive from in situ lobular lesions
-
Zou D, Yoon HS, Anjomshoaa A, Perez D, Fukuzawa R, et al. (2009) Increased levels of active c-Src distinguish invasive from in situ lobular lesions. Breast Cancer Res 11: R45.
-
(2009)
Breast Cancer Res
, vol.11
-
-
Zou, D.1
Yoon, H.S.2
Anjomshoaa, A.3
Perez, D.4
Fukuzawa, R.5
-
38
-
-
79953745096
-
Combating trastuzumab resistance by targeting SRC, a common node downstream of multiple resistance pathways
-
Zhang S, Huang WC, Li P, Guo H, Poh SB, et al. (2011) Combating trastuzumab resistance by targeting SRC, a common node downstream of multiple resistance pathways. Nat Med 17: 461-469.
-
(2011)
Nat Med
, vol.17
, pp. 461-469
-
-
Zhang, S.1
Huang, W.C.2
Li, P.3
Guo, H.4
Poh, S.B.5
-
39
-
-
85027909385
-
KX-01, a novel Src kinase inhibitor directed toward the peptide substrate site, synergizes with tamoxifen in estrogen receptor alpha positive breast cancer
-
Anbalagan M, Carrier L, Glodowski S, Hangauer D, Shan B, et al. (2011) KX-01, a novel Src kinase inhibitor directed toward the peptide substrate site, synergizes with tamoxifen in estrogen receptor alpha positive breast cancer. Breast Cancer Res Treat.
-
(2011)
Breast Cancer Res Treat
-
-
Anbalagan, M.1
Carrier, L.2
Glodowski, S.3
Hangauer, D.4
Shan, B.5
-
40
-
-
0036672963
-
Cyclooxygenase 2 expression in pancreatic adenocarcinoma and pancreatic intraepithelial neoplasia: an immunohistochemical analysis with automated cellular imaging
-
Maitra A, Ashfaq R, Gunn CR, Rahman A, Yeo CJ, et al. (2002) Cyclooxygenase 2 expression in pancreatic adenocarcinoma and pancreatic intraepithelial neoplasia: an immunohistochemical analysis with automated cellular imaging. Am J Clin Pathol 118: 194-201.
-
(2002)
Am J Clin Pathol
, vol.118
, pp. 194-201
-
-
Maitra, A.1
Ashfaq, R.2
Gunn, C.R.3
Rahman, A.4
Yeo, C.J.5
-
41
-
-
0027394794
-
Association of p53 protein expression with tumor cell proliferation rate and clinical outcome in node-negative breast cancer
-
Allred DC, Clark GM, Elledge R, Fuqua SA, Brown RW, et al. (1993) Association of p53 protein expression with tumor cell proliferation rate and clinical outcome in node-negative breast cancer. J Natl Cancer Inst 85: 200-206.
-
(1993)
J Natl Cancer Inst
, vol.85
, pp. 200-206
-
-
Allred, D.C.1
Clark, G.M.2
Elledge, R.3
Fuqua, S.A.4
Brown, R.W.5
|