메뉴 건너뛰기




Volumn 21, Issue 1, 2015, Pages 81-94

Mitochondrial genome acquisition restores respiratory function and tumorigenic potential of cancer cells without mitochondrial DNA

(25)  Tan, An S a   Baty, James W a   Dong, Lan Feng b   Bezawork Geleta, Ayenachew b   Endaya, Berwini b   Goodwin, Jacob b   Bajzikova, Martina c   Kovarova, Jaromira c   Peterka, Martin c   Yan, Bing b   Pesdar, Elham Alizadeh b   Sobol, Margarita d   Filimonenko, Anatolyj d   Stuart, Shani e   Vondrusova, Magdalena c   Kluckova, Katarina c   Sachaphibulkij, Karishma b   Rohlena, Jakub c   Hozak, Pavel d   Truksa, Jaroslav c   more..


Author keywords

[No Author keywords available]

Indexed keywords

MITOCHONDRIAL DNA; CITRATE SYNTHASE; MESSENGER RNA; MULTIENZYME COMPLEX; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE;

EID: 84920560830     PISSN: 15504131     EISSN: 19327420     Source Type: Journal    
DOI: 10.1016/j.cmet.2014.12.003     Document Type: Article
Times cited : (573)

References (62)
  • 2
    • 81255210901 scopus 로고    scopus 로고
    • Arrangement of electron transport chain components in bovine mitochondrial supercomplex I1III2IV1
    • T. Althoff, D.J. Mills, J.L. Popot, and W. Kühlbrandt Arrangement of electron transport chain components in bovine mitochondrial supercomplex I1III2IV1 EMBO J. 30 2011 4652 4664
    • (2011) EMBO J. , vol.30 , pp. 4652-4664
    • Althoff, T.1    Mills, D.J.2    Popot, J.L.3    Kühlbrandt, W.4
  • 4
    • 33746466098 scopus 로고    scopus 로고
    • Mitochondrial mutations in cancer
    • M. Brandon, P. Baldi, and D.C. Wallace Mitochondrial mutations in cancer Oncogene 25 2006 4647 4662
    • (2006) Oncogene , vol.25 , pp. 4647-4662
    • Brandon, M.1    Baldi, P.2    Wallace, D.C.3
  • 5
    • 67349244755 scopus 로고    scopus 로고
    • Selective block of tunneling nanotube (TNT) formation inhibits intercellular organelle transfer between PC12 cells
    • N.V. Bukoreshtliev, X. Wang, E. Hodneland, S. Gurke, J.F. Barroso, and H.H. Gerdes Selective block of tunneling nanotube (TNT) formation inhibits intercellular organelle transfer between PC12 cells FEBS Lett. 583 2009 1481 1488
    • (2009) FEBS Lett. , vol.583 , pp. 1481-1488
    • Bukoreshtliev, N.V.1    Wang, X.2    Hodneland, E.3    Gurke, S.4    Barroso, J.F.5    Gerdes, H.H.6
  • 6
    • 0030728737 scopus 로고    scopus 로고
    • Diminished tumorigenic phenotype after depletion of mitochondrial DNA
    • L.R. Cavalli, M. Varella-Garcia, and B.C. Liang Diminished tumorigenic phenotype after depletion of mitochondrial DNA Cell Growth Differ. 8 1997 1189 1198
    • (1997) Cell Growth Differ. , vol.8 , pp. 1189-1198
    • Cavalli, L.R.1    Varella-Garcia, M.2    Liang, B.C.3
  • 7
    • 84860652940 scopus 로고    scopus 로고
    • Mesenchymal stem cells transfer mitochondria to the cells with virtually no mitochondrial function but not with pathogenic mtDNA mutations
    • Y.M. Cho, J.H. Kim, M. Kim, S.J. Park, S.H. Koh, H.S. Ahn, G.H. Kang, J.B. Lee, K.S. Park, and H.K. Lee Mesenchymal stem cells transfer mitochondria to the cells with virtually no mitochondrial function but not with pathogenic mtDNA mutations PLoS ONE 7 2012 e32778
    • (2012) PLoS ONE , vol.7 , pp. e32778
    • Cho, Y.M.1    Kim, J.H.2    Kim, M.3    Park, S.J.4    Koh, S.H.5    Ahn, H.S.6    Kang, G.H.7    Lee, J.B.8    Park, K.S.9    Lee, H.K.10
  • 10
    • 37449034854 scopus 로고    scopus 로고
    • Beyond aerobic glycolysis: Transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis
    • R.J. DeBerardinis, A. Mancuso, E. Daikhin, I. Nissim, M. Yudkoff, S. Wehrli, and C.B. Thompson Beyond aerobic glycolysis: transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis Proc. Natl. Acad. Sci. USA 104 2007 19345 19350
    • (2007) Proc. Natl. Acad. Sci. USA , vol.104 , pp. 19345-19350
    • Deberardinis, R.J.1    Mancuso, A.2    Daikhin, E.3    Nissim, I.4    Yudkoff, M.5    Wehrli, S.6    Thompson, C.B.7
  • 12
  • 13
    • 47149114386 scopus 로고    scopus 로고
    • Intercellular transfer mediated by tunneling nanotubes
    • H.H. Gerdes, and R.N. Carvalho Intercellular transfer mediated by tunneling nanotubes Curr. Opin. Cell Biol. 20 2008 470 475
    • (2008) Curr. Opin. Cell Biol. , vol.20 , pp. 470-475
    • Gerdes, H.H.1    Carvalho, R.N.2
  • 14
    • 79957923566 scopus 로고    scopus 로고
    • Mitochondria regulate autophagy by conserved signalling pathways
    • M. Graef, and J. Nunnari Mitochondria regulate autophagy by conserved signalling pathways EMBO J. 30 2011 2101 2114
    • (2011) EMBO J. , vol.30 , pp. 2101-2114
    • Graef, M.1    Nunnari, J.2
  • 15
    • 84884337715 scopus 로고    scopus 로고
    • Mitochondrial retrograde signaling at the crossroads of tumor bioenergetics, genetics and epigenetics
    • M. Guha, and N.G. Avadhani Mitochondrial retrograde signaling at the crossroads of tumor bioenergetics, genetics and epigenetics Mitochondrion 13 2013 577 591
    • (2013) Mitochondrion , vol.13 , pp. 577-591
    • Guha, M.1    Avadhani, N.G.2
  • 16
    • 56249115528 scopus 로고    scopus 로고
    • Tunneling nanotube (TNT)-like structures facilitate a constitutive, actomyosin-dependent exchange of endocytic organelles between normal rat kidney cells
    • S. Gurke, J.F. Barroso, E. Hodneland, N.V. Bukoreshtliev, O. Schlicker, and H.H. Gerdes Tunneling nanotube (TNT)-like structures facilitate a constitutive, actomyosin-dependent exchange of endocytic organelles between normal rat kidney cells Exp. Cell Res. 314 2008 3669 3683
    • (2008) Exp. Cell Res. , vol.314 , pp. 3669-3683
    • Gurke, S.1    Barroso, J.F.2    Hodneland, E.3    Bukoreshtliev, N.V.4    Schlicker, O.5    Gerdes, H.H.6
  • 17
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: The next generation
    • D. Hanahan, and R.A. Weinberg Hallmarks of cancer: the next generation Cell 144 2011 646 674
    • (2011) Cell , vol.144 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 18
    • 0026697079 scopus 로고
    • Recovery of the missing tumorigenicity in mitochondrial DNA-less HeLa cells by introduction of mitochondrial DNA from normal human cells
    • J. Hayashi, M. Takemitsu, and I. Nonaka Recovery of the missing tumorigenicity in mitochondrial DNA-less HeLa cells by introduction of mitochondrial DNA from normal human cells Somat. Cell Mol. Genet. 18 1992 123 129
    • (1992) Somat. Cell Mol. Genet. , vol.18 , pp. 123-129
    • Hayashi, J.1    Takemitsu, M.2    Nonaka, I.3
  • 19
    • 33847127936 scopus 로고    scopus 로고
    • Cell surface oxygen consumption: A major contributor to cellular oxygen consumption in glycolytic cancer cell lines
    • P.M. Herst, and M.V. Berridge Cell surface oxygen consumption: a major contributor to cellular oxygen consumption in glycolytic cancer cell lines Biochim. Biophys. Acta 1767 2007 170 177
    • (2007) Biochim. Biophys. Acta , vol.1767 , pp. 170-177
    • Herst, P.M.1    Berridge, M.V.2
  • 20
    • 79251539264 scopus 로고    scopus 로고
    • The level of glycolytic metabolism in acute myeloid leukemia blasts at diagnosis is prognostic for clinical outcome
    • P.M. Herst, R.A. Howman, P.J. Neeson, M.V. Berridge, and D.S. Ritchie The level of glycolytic metabolism in acute myeloid leukemia blasts at diagnosis is prognostic for clinical outcome J. Leukoc. Biol. 89 2011 51 55
    • (2011) J. Leukoc. Biol. , vol.89 , pp. 51-55
    • Herst, P.M.1    Howman, R.A.2    Neeson, P.J.3    Berridge, M.V.4    Ritchie, D.S.5
  • 21
    • 84880387219 scopus 로고    scopus 로고
    • A stabilizing factor for mitochondrial respiratory supercomplex assembly regulates energy metabolism in muscle
    • K. Ikeda, S. Shiba, K. Horie-Inoue, K. Shimokata, and S. Inoue A stabilizing factor for mitochondrial respiratory supercomplex assembly regulates energy metabolism in muscle Nat. Commun. 4 2013 2147
    • (2013) Nat. Commun. , vol.4 , pp. 2147
    • Ikeda, K.1    Shiba, S.2    Horie-Inoue, K.3    Shimokata, K.4    Inoue, S.5
  • 27
    • 0023920693 scopus 로고
    • Injection of mitochondria into human cells leads to a rapid replacement of the endogenous mitochondrial DNA
    • M.P. King, and G. Attardi Injection of mitochondria into human cells leads to a rapid replacement of the endogenous mitochondrial DNA Cell 52 1988 811 819
    • (1988) Cell , vol.52 , pp. 811-819
    • King, M.P.1    Attardi, G.2
  • 28
    • 0024448458 scopus 로고
    • Human cells lacking mtDNA: Repopulation with exogenous mitochondria by complementation
    • M.P. King, and G. Attardi Human cells lacking mtDNA: repopulation with exogenous mitochondria by complementation Science 246 1989 500 503
    • (1989) Science , vol.246 , pp. 500-503
    • King, M.P.1    Attardi, G.2
  • 29
    • 20344381347 scopus 로고    scopus 로고
    • Cell-to-cell connection of endothelial progenitor cells with cardiac myocytes by nanotubes: A novel mechanism for cell fate changes?
    • M. Koyanagi, R.P. Brandes, J. Haendeler, A.M. Zeiher, and S. Dimmeler Cell-to-cell connection of endothelial progenitor cells with cardiac myocytes by nanotubes: a novel mechanism for cell fate changes? Circ. Res. 96 2005 1039 1041
    • (2005) Circ. Res. , vol.96 , pp. 1039-1041
    • Koyanagi, M.1    Brandes, R.P.2    Haendeler, J.3    Zeiher, A.M.4    Dimmeler, S.5
  • 31
    • 44449147036 scopus 로고    scopus 로고
    • Tumor cell metabolism: Cancer's Achilles' heel
    • G. Kroemer, and J. Pouyssegur Tumor cell metabolism: cancer's Achilles' heel Cancer Cell 13 2008 472 482
    • (2008) Cancer Cell , vol.13 , pp. 472-482
    • Kroemer, G.1    Pouyssegur, J.2
  • 32
    • 84882835838 scopus 로고    scopus 로고
    • MtDNA makes a U-turn for the mitochondrial nucleoid
    • C. Kukat, and N.G. Larsson mtDNA makes a U-turn for the mitochondrial nucleoid Trends Cell Biol. 23 2013 457 463
    • (2013) Trends Cell Biol. , vol.23 , pp. 457-463
    • Kukat, C.1    Larsson, N.G.2
  • 33
    • 56449097919 scopus 로고    scopus 로고
    • Tumorigenic transformation of human breast epithelial cells induced by mitochondrial DNA depletion
    • M. Kulawiec, A. Safina, M.M. Desouki, I. Still, S. Matsui, A. Bakin, and K.K. Singh Tumorigenic transformation of human breast epithelial cells induced by mitochondrial DNA depletion Cancer Biol. Ther. 7 2008 1732 1743
    • (2008) Cancer Biol. Ther. , vol.7 , pp. 1732-1743
    • Kulawiec, M.1    Safina, A.2    Desouki, M.M.3    Still, I.4    Matsui, S.5    Bakin, A.6    Singh, K.K.7
  • 36
    • 33845656956 scopus 로고    scopus 로고
    • Mitochondrial retrograde signaling
    • Z. Liu, and R.A. Butow Mitochondrial retrograde signaling Annu. Rev. Genet. 40 2006 159 185
    • (2006) Annu. Rev. Genet. , vol.40 , pp. 159-185
    • Liu, Z.1    Butow, R.A.2
  • 38
    • 68149137896 scopus 로고    scopus 로고
    • Implications of mitochondrial DNA mutations and mitochondrial dysfunction in tumorigenesis
    • J. Lu, L.K. Sharma, and Y. Bai Implications of mitochondrial DNA mutations and mitochondrial dysfunction in tumorigenesis Cell Res. 19 2009 802 815
    • (2009) Cell Res. , vol.19 , pp. 802-815
    • Lu, J.1    Sharma, L.K.2    Bai, Y.3
  • 40
    • 0028107856 scopus 로고
    • Tumor-forming ability in athymic nude mice of human cell lines devoid of mitochondrial DNA
    • R. Morais, K. Zinkewich-Péotti, M. Parent, H. Wang, F. Babai, and M. Zollinger Tumor-forming ability in athymic nude mice of human cell lines devoid of mitochondrial DNA Cancer Res. 54 1994 3889 3896
    • (1994) Cancer Res. , vol.54 , pp. 3889-3896
    • Morais, R.1    Zinkewich-Péotti, K.2    Parent, M.3    Wang, H.4    Babai, F.5    Zollinger, M.6
  • 43
    • 34249873947 scopus 로고    scopus 로고
    • Translocation of proteins into mitochondria
    • W. Neupert, and J.M. Herrmann Translocation of proteins into mitochondria Annu. Rev. Biochem. 76 2007 723 749
    • (2007) Annu. Rev. Biochem. , vol.76 , pp. 723-749
    • Neupert, W.1    Herrmann, J.M.2
  • 45
    • 82355161907 scopus 로고    scopus 로고
    • High-resolution respirometry: OXPHOS protocols for human cells and permeabilized fibers from small biopsies of human muscle
    • D. Pesta, and E. Gnaiger High-resolution respirometry: OXPHOS protocols for human cells and permeabilized fibers from small biopsies of human muscle Methods Mol. Biol. 810 2012 25 58
    • (2012) Methods Mol. Biol. , vol.810 , pp. 25-58
    • Pesta, D.1    Gnaiger, E.2
  • 47
    • 84886099830 scopus 로고    scopus 로고
    • Mutations in regulators of the epigenome and their connections to global chromatin patterns in cancer
    • C. Plass, S.M. Pfister, A.M. Lindroth, O. Bogatyrova, R. Claus, and P. Lichter Mutations in regulators of the epigenome and their connections to global chromatin patterns in cancer Nat. Rev. Genet. 14 2013 765 780
    • (2013) Nat. Rev. Genet. , vol.14 , pp. 765-780
    • Plass, C.1    Pfister, S.M.2    Lindroth, A.M.3    Bogatyrova, O.4    Claus, R.5    Lichter, P.6
  • 48
    • 77951432631 scopus 로고    scopus 로고
    • The causes of cancer revisited: "Mitochondrial malignancy" and ROS-induced oncogenic transformation - Why mitochondria are targets for cancer therapy
    • S.J. Ralph, S. Rodríguez-Enríquez, J. Neuzil, E. Saavedra, and R. Moreno-Sánchez The causes of cancer revisited: "mitochondrial malignancy" and ROS-induced oncogenic transformation - why mitochondria are targets for cancer therapy Mol. Aspects Med. 31 2010 145 170
    • (2010) Mol. Aspects Med. , vol.31 , pp. 145-170
    • Ralph, S.J.1    Rodríguez-Enríquez, S.2    Neuzil, J.3    Saavedra, E.4    Moreno-Sánchez, R.5
  • 49
    • 78751689621 scopus 로고    scopus 로고
    • Mitochondrial capture by a transmissible cancer
    • C.A. Rebbeck, A.M. Leroi, and A. Burt Mitochondrial capture by a transmissible cancer Science 331 2011 303
    • (2011) Science , vol.331 , pp. 303
    • Rebbeck, C.A.1    Leroi, A.M.2    Burt, A.3
  • 51
    • 1142286348 scopus 로고    scopus 로고
    • Nanotubular highways for intercellular organelle transport
    • A. Rustom, R. Saffrich, I. Markovic, P. Walther, and H.H. Gerdes Nanotubular highways for intercellular organelle transport Science 303 2004 1007 1010
    • (2004) Science , vol.303 , pp. 1007-1010
    • Rustom, A.1    Saffrich, R.2    Markovic, I.3    Walther, P.4    Gerdes, H.H.5
  • 52
    • 34250811284 scopus 로고    scopus 로고
    • Mitochondrial-nuclear communications
    • M.T. Ryan, and N.J. Hoogenraad Mitochondrial-nuclear communications Annu. Rev. Biochem. 76 2007 701 722
    • (2007) Annu. Rev. Biochem. , vol.76 , pp. 701-722
    • Ryan, M.T.1    Hoogenraad, N.J.2
  • 53
    • 0038230469 scopus 로고    scopus 로고
    • Supercomplexes in the respiratory chains of yeast and mammalian mitochondria
    • H. Schägger, and K. Pfeiffer Supercomplexes in the respiratory chains of yeast and mammalian mitochondria EMBO J. 19 2000 1777 1783
    • (2000) EMBO J. , vol.19 , pp. 1777-1783
    • Schägger, H.1    Pfeiffer, K.2
  • 55
    • 84869397441 scopus 로고    scopus 로고
    • Human mitochondrial DNA: Roles of inherited and somatic mutations
    • E.A. Schon, S. DiMauro, and M. Hirano Human mitochondrial DNA: roles of inherited and somatic mutations Nat. Rev. Genet. 13 2012 878 890
    • (2012) Nat. Rev. Genet. , vol.13 , pp. 878-890
    • Schon, E.A.1    Dimauro, S.2    Hirano, M.3
  • 57
    • 0035499457 scopus 로고    scopus 로고
    • Reprogramming of genome function through epigenetic inheritance
    • M.A. Surani Reprogramming of genome function through epigenetic inheritance Nature 414 2001 122 128
    • (2001) Nature , vol.414 , pp. 122-128
    • Surani, M.A.1
  • 58
    • 84895525043 scopus 로고    scopus 로고
    • The role of mitochondrial electron transport in tumorigenesis and metastasis
    • A.S. Tan, J.W. Baty, and M.V. Berridge The role of mitochondrial electron transport in tumorigenesis and metastasis Biochim. Biophys. Acta 1840 2014 1454 1463
    • (2014) Biochim. Biophys. Acta , vol.1840 , pp. 1454-1463
    • Tan, A.S.1    Baty, J.W.2    Berridge, M.V.3
  • 60
    • 66249108601 scopus 로고    scopus 로고
    • Understanding the Warburg effect: The metabolic requirements of cell proliferation
    • M.G. Vander Heiden, L.C. Cantley, and C.B. Thompson Understanding the Warburg effect: the metabolic requirements of cell proliferation Science 324 2009 1029 1033
    • (2009) Science , vol.324 , pp. 1029-1033
    • Vander Heiden, M.G.1    Cantley, L.C.2    Thompson, C.B.3
  • 61
    • 84866665390 scopus 로고    scopus 로고
    • Mitochondria and cancer
    • D.C. Wallace Mitochondria and cancer Nat. Rev. Cancer 12 2012 685 698
    • (2012) Nat. Rev. Cancer , vol.12 , pp. 685-698
    • Wallace, D.C.1
  • 62
    • 70450231612 scopus 로고    scopus 로고
    • Energetics, epigenetics, mitochondrial genetics
    • D.C. Wallace, and W. Fan Energetics, epigenetics, mitochondrial genetics Mitochondrion 10 2010 12 31
    • (2010) Mitochondrion , vol.10 , pp. 12-31
    • Wallace, D.C.1    Fan, W.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.