Bioisosteric Exchange of C sp 3 -Chloro and Methyl Substituents: Synthesis and Initial Biological Studies of Atpenin A5 Analogues

Angewandte Chemie - International Edition

Volumn 55, Issue 12, 2016, Pages 4049-4053

  Krautwald, Simon ^a   Nilewski, Christian ^a   Mori, Mihoko ^b   Shiomi, Kazuro ^b   Omura, Satoshi ^b   Carreira, Erick M ^a  

^a ETH ZURICH   (Switzerland)

^b KITASATO UNIVERSITY   (Japan)

Author keywords

antifungal agents; atpenins; bioisosterism; chlorinated natural products; inhibition of respiratory chain

Indexed keywords

CHAINS; FUNGICIDES;

ASYMMETRIC SYNTHESIS; ATPENINS; BIOISOSTERISM; BIOLOGICAL STUDIES; NATURAL PRODUCTS; NATURALLY OCCURRING; RESPIRATORY CHAINS; SIDE-CHAINS;

ANTIFUNGAL AGENTS;

ANTIFUNGAL AGENT; ATPENIN A5; PYRIDONE DERIVATIVE;

CHEMICAL STRUCTURE; CHEMISTRY;

ANTIFUNGAL AGENTS; MOLECULAR STRUCTURE; PYRIDONES;

EID: 84960416049     PISSN: 14337851     EISSN: 15213773     Source Type: Journal    
DOI: 10.1002/anie.201511672     Document Type: Article

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