ω-3 fatty acids as an adjuvant therapy ameliorates methotrexate-induced hepatotoxicity in children and adolescents with acute lymphoblastic leukemia: A randomized placebo-controlled study

Nutrition

Volumn 32, Issue 1, 2016, Pages 41-47

  Elbarbary, Nancy Samir ^a   Ismail, Eman Abdel Rahman ^a   Farahat, Reham Kamel ^b   El Hamamsy, Manal ^b  

^a AIN SHAMS UNIVERSITY   (Egypt)

^b African Union Organization St Abbassia   (Egypt)

Author keywords

Acute lymphoblastic leukemia; Hepatotoxicity; Methotrexate; Oxidative stress; 3 fatty acids

Indexed keywords

ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; GAMMA GLUTAMYLTRANSFERASE; GLUTATHIONE PEROXIDASE; LIVER ENZYME; MALONALDEHYDE; METHOTREXATE; OMEGA 3 FATTY ACID; PLACEBO; SUPEROXIDE DISMUTASE; URIC ACID; ANTIOXIDANT;

ABSENCE OF SIDE EFFECTS; ACUTE LYMPHOBLASTIC LEUKEMIA; ADJUVANT THERAPY; ADOLESCENT; ANTIOXIDANT ACTIVITY; ARTICLE; CHILD; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG SAFETY; DRUG TOLERABILITY; ENZYME ANALYSIS; FEMALE; FOLLOW UP; HUMAN; LIVER FUNCTION; LIVER TOXICITY; MAJOR CLINICAL STUDY; MALE; MORNING DOSAGE; OXIDATIVE STRESS; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; TREATMENT DURATION; TREATMENT OUTCOME; DRUG EFFECTS; LIVER; METABOLISM; PRECURSOR CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; PRESCHOOL CHILD; TOXIC HEPATITIS;

ADOLESCENT; ANTIOXIDANTS; CHILD; CHILD, PRESCHOOL; DOUBLE-BLIND METHOD; DRUG-INDUCED LIVER INJURY; FATTY ACIDS, OMEGA-3; FEMALE; GLUTATHIONE PEROXIDASE; HUMANS; LIVER; MALE; MALONDIALDEHYDE; METHOTREXATE; OXIDATIVE STRESS; PRECURSOR CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; SUPEROXIDE DISMUTASE;

EID: 84959523118     PISSN: 08999007     EISSN: 18731244     Source Type: Journal    
DOI: 10.1016/j.nut.2015.06.010     Document Type: Article

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