Combination of coenzyme Q10 with methotrexate suppresses Freund's complete adjuvant-induced synovial inflammation with reduced hepatotoxicity in rats: Effect on oxidative stress and inflammation

International Immunopharmacology

Volumn 24, Issue 1, 2014, Pages 80-87

  Tawfik, Mona K ^a  

^a Suez Canal University Faculty of Medicine   (Egypt)

Author keywords

Coenzyme Q10; Freund's complete adjuvant; Hepatotoxicity; Methotreaxate; Rat

Indexed keywords

ALANINE AMINOTRANSFERASE; ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; BILIRUBIN; CATALASE; FREUND ADJUVANT; GLUTATHIONE; INTERLEUKIN 6; LIPID PEROXIDE; MALONALDEHYDE; METHOTREXATE; SUPEROXIDE DISMUTASE; TUMOR NECROSIS FACTOR ALPHA; UBIDECARENONE; ANTIOXIDANT; ANTIRHEUMATIC AGENT; AUTACOID; UBIQUINONE;

ADJUVANT ARTHRITIS; ADJUVANT THERAPY; ADULT; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALKALINE PHOSPHATASE BLOOD LEVEL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BILIRUBIN BLOOD LEVEL; CELL DEATH; CELL HYPERPLASIA; CONTROLLED STUDY; DISEASE COURSE; DISEASE EXACERBATION; DISEASE SEVERITY; DOWN REGULATION; DRUG EFFECT; HEPATITIS; HISTOPATHOLOGY; INFLAMMATORY INFILTRATE; KUPFFER CELL; LIVER CELL; LIVER NECROSIS; LIVER PARENCHYMA; LIVER TOXICITY; MALE; NONHUMAN; OXIDATIVE STRESS; PROTEIN BLOOD LEVEL; RAT; SYNOVIUM; ANALOGS AND DERIVATIVES; ANIMAL; ARTHRITIS, EXPERIMENTAL; CELL CULTURE; DRUG COMBINATION; DRUG EFFECTS; DRUG POTENTIATION; IMMUNOLOGY; LIVER; METABOLISM; PATHOLOGY; WISTAR RAT;

ANIMALS; ANTIOXIDANTS; ANTIRHEUMATIC AGENTS; ARTHRITIS, EXPERIMENTAL; CELLS, CULTURED; DRUG SYNERGISM; DRUG THERAPY, COMBINATION; INFLAMMATION MEDIATORS; INTERLEUKIN-6; LIVER; MALE; METHOTREXATE; OXIDATIVE STRESS; RATS; RATS, WISTAR; SYNOVIAL MEMBRANE; TUMOR NECROSIS FACTOR-ALPHA; UBIQUINONE;

EID: 84915746563     PISSN: 15675769     EISSN: 18781705     Source Type: Journal    
DOI: 10.1016/j.intimp.2014.11.018     Document Type: Article

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