-
1
-
-
84953366095
-
Proteomic analysis of integrin-associated complexes from mesenchymal stem cells
-
Ajeian, J.N., E.R. Horton, P. Astudillo, A. Byron, J.A. Askari, A. Millon-Frémillon, D. Knight, S.J. Kimber, M.J. Humphries, and J.D. Humphries. 2015. Proteomic analysis of integrin-associated complexes from mesenchymal stem cells. Proteomics Clin. Appl. http://dx.doi.org/10.1002/prca.201500033
-
(2015)
Proteomics Clin. Appl.
-
-
Ajeian, J.N.1
Horton, E.R.2
Astudillo, P.3
Byron, A.4
Askari, J.A.5
Millon-Frémillon, A.6
Knight, D.7
Kimber, S.J.8
Humphries, M.J.9
Humphries, J.D.10
-
2
-
-
84906314998
-
Integrin-associated complexes form hierarchically with variable stoichiometry in nascent adhesions
-
Bachir, A.I., J. Zareno, K. Moissoglu, E.F. Plow, E. Gratton, and A.R. Horwitz. 2014. Integrin-associated complexes form hierarchically with variable stoichiometry in nascent adhesions. Curr. Biol. 24:1845-1853. http://dx.doi.org/10.1016/j.cub.2014.07.011
-
(2014)
Curr. Biol.
, vol.24
, pp. 1845-1853
-
-
Bachir, A.I.1
Zareno, J.2
Moissoglu, K.3
Plow, E.F.4
Gratton, E.5
Horwitz, A.R.6
-
3
-
-
0037392942
-
The specificities of protein kinase inhibitors: an update
-
Bain, J., H. McLauchlan, M. Elliott, and P. Cohen. 2003. The specificities of protein kinase inhibitors: an update. Biochem. J. 371:199-204. http://dx.doi.org/10.1042/bj20021535
-
(2003)
Biochem. J.
, vol.371
, pp. 199-204
-
-
Bain, J.1
McLauchlan, H.2
Elliott, M.3
Cohen, P.4
-
4
-
-
33645234372
-
Molecular mapping of tyrosine-phosphorylated proteins in focal adhesions using fluorescence resonance energy transfer
-
Ballestrem, C., N. Erez, J. Kirchner, Z. Kam, A. Bershadsky, and B. Geiger. 2006. Molecular mapping of tyrosine-phosphorylated proteins in focal adhesions using fluorescence resonance energy transfer. J. Cell Sci. 119:866-875. http://dx.doi.org/10.1242/jcs.02794
-
(2006)
J. Cell Sci.
, vol.119
, pp. 866-875
-
-
Ballestrem, C.1
Erez, N.2
Kirchner, J.3
Kam, Z.4
Bershadsky, A.5
Geiger, B.6
-
5
-
-
0030266491
-
Involvement of microtubules in the control of adhesion-dependent signal transduction
-
Bershadsky, A., A. Chausovsky, E. Becker, A. Lyubimova, and B. Geiger. 1996. Involvement of microtubules in the control of adhesion-dependent signal transduction. Curr. Biol. 6:1279-1289. http://dx.doi.org/10.1016/S0960-9822(02)70714-8
-
(1996)
Curr. Biol.
, vol.6
, pp. 1279-1289
-
-
Bershadsky, A.1
Chausovsky, A.2
Becker, E.3
Lyubimova, A.4
Geiger, B.5
-
6
-
-
0037904987
-
The integrin-actin connection, an eternal love affair
-
Brakebusch, C., and R. Fässler. 2003. The integrin-actin connection, an eternal love affair. EMBO J. 22:2324-2333. http://dx.doi.org/10.1093/emboj/cdg245
-
(2003)
EMBO J.
, vol.22
, pp. 2324-2333
-
-
Brakebusch, C.1
Fässler, R.2
-
7
-
-
84897862926
-
FAK dimerization controls its kinase-dependent functions at focal adhesions
-
Brami-Cherrier, K., N. Gervasi, D. Arsenieva, K. Walkiewicz, M.C. Boutterin, A. Ortega, P.G. Leonard, B. Seantier, L. Gasmi, T. Bouceba, et al. 2014. FAK dimerization controls its kinase-dependent functions at focal adhesions. EMBO J. 33:356-370. http://dx.doi.org/10.1002/embj.201386399
-
(2014)
EMBO J.
, vol.33
, pp. 356-370
-
-
Brami-Cherrier, K.1
Gervasi, N.2
Arsenieva, D.3
Walkiewicz, K.4
Boutterin, M.C.5
Ortega, A.6
Leonard, P.G.7
Seantier, B.8
Gasmi, L.9
Bouceba, T.10
-
8
-
-
51449088226
-
Src and focal adhesion kinase as therapeutic targets in cancer
-
Brunton, V.G., and M.C. Frame. 2008. Src and focal adhesion kinase as therapeutic targets in cancer. Curr. Opin. Pharmacol. 8:427-432. http://dx.doi.org/10.1016/j.coph.2008.06.012
-
(2008)
Curr. Opin. Pharmacol.
, vol.8
, pp. 427-432
-
-
Brunton, V.G.1
Frame, M.C.2
-
9
-
-
78650433328
-
Adhesion signalling complexes
-
Byron, A., M.R. Morgan, and M.J. Humphries. 2010. Adhesion signalling complexes. Curr. Biol. 20:R1063-R1067. http://dx.doi.org/10.1016/j.cub.2010.10.059
-
(2010)
Curr. Biol.
, vol.20
, pp. R1063-R1067
-
-
Byron, A.1
Morgan, M.R.2
Humphries, M.J.3
-
10
-
-
84862653023
-
Proteomic analysis of α4β1 integrin adhesion complexes reveals α-subunit-dependent protein recruitment
-
Byron, A., J.D. Humphries, S.E. Craig, D. Knight, and M.J. Humphries. 2012. Proteomic analysis of α4β1 integrin adhesion complexes reveals α-subunit-dependent protein recruitment. Proteomics. 12:2107-2114. http://dx.doi.org/10.1002/pmic.201100487
-
(2012)
Proteomics.
, vol.12
, pp. 2107-2114
-
-
Byron, A.1
Humphries, J.D.2
Craig, S.E.3
Knight, D.4
Humphries, M.J.5
-
11
-
-
84937636601
-
A proteomic approach reveals integrin activation state-dependent control of microtubule cortical targeting
-
Byron, A., J.A. Askari, J.D. Humphries, G. Jacquemet, E.J. Koper, S. Warwood, C.K. Choi, M.J. Stroud, C.S. Chen, D. Knight, and M.J. Humphries. 2015. A proteomic approach reveals integrin activation state-dependent control of microtubule cortical targeting. Nat. Commun. 6:6135. http://dx.doi.org/10.1038/ncomms7135
-
(2015)
Nat. Commun.
, vol.6
, pp. 6135
-
-
Byron, A.1
Askari, J.A.2
Humphries, J.D.3
Jacquemet, G.4
Koper, E.J.5
Warwood, S.6
Choi, C.K.7
Stroud, M.J.8
Chen, C.S.9
Knight, D.10
Humphries, M.J.11
-
12
-
-
0028877919
-
Tyrosine phosphorylation of focal adhesion kinase at sites in the catalytic domain regulates kinase activity: a role for Src family kinases
-
Calalb, M.B., T.R. Polte, and S.K. Hanks. 1995. Tyrosine phosphorylation of focal adhesion kinase at sites in the catalytic domain regulates kinase activity: a role for Src family kinases. Mol. Cell. Biol. 15:954-963. http://dx.doi.org/10.1128/MCB.15.2.954
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 954-963
-
-
Calalb, M.B.1
Polte, T.R.2
Hanks, S.K.3
-
13
-
-
77951242361
-
Regulation of adhesion dynamics by calpain-mediated proteolysis of focal adhesion kinase (FAK)
-
Chan, K.T., D.A. Bennin, and A. Huttenlocher. 2010. Regulation of adhesion dynamics by calpain-mediated proteolysis of focal adhesion kinase (FAK). J. Biol. Chem. 285:11418-11426. http://dx.doi.org/10.1074/jbc. M109.090746
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 11418-11426
-
-
Chan, K.T.1
Bennin, D.A.2
Huttenlocher, A.3
-
14
-
-
61449243886
-
MatrixDB, a database focused on extracellular protein-protein and proteincarbohydrate interactions
-
Chautard, E., L. Ballut, N. Thierry-Mieg, and S. Ricard-Blum. 2009. MatrixDB, a database focused on extracellular protein-protein and proteincarbohydrate interactions. Bioinformatics. 25:690-691. http://dx.doi.org/10.1093/bioinformatics/btp025
-
(2009)
Bioinformatics.
, vol.25
, pp. 690-691
-
-
Chautard, E.1
Ballut, L.2
Thierry-Mieg, N.3
Ricard-Blum, S.4
-
15
-
-
66049088456
-
Combined integrin phosphoproteomic analyses and siRNA-based functional screening identified key regulators for cancer cell adhesion and migration
-
Chen, Y., B. Lu, Q. Yang, C. Fearns, J.R. Yates, and J.-D. Lee. 2009. Combined integrin phosphoproteomic analyses and siRNA-based functional screening identified key regulators for cancer cell adhesion and migration. Cancer Res. 69:3713-3720. http://dx.doi.org/10.1158/0008-5472.CAN-08-2515
-
(2009)
Cancer Res.
, vol.69
, pp. 3713-3720
-
-
Chen, Y.1
Lu, B.2
Yang, Q.3
Fearns, C.4
Yates, J.R.5
Lee, J.-D.6
-
16
-
-
51049104617
-
Actin and α-actinin orchestrate the assembly and maturation of nascent adhesions in a myosin II motor-independent manner
-
Choi, C.K., M. Vicente-Manzanares, J. Zareno, L.A. Whitmore, A. Mogilner, and A.R. Horwitz. 2008. Actin and α-actinin orchestrate the assembly and maturation of nascent adhesions in a myosin II motor-independent manner. Nat. Cell Biol. 10:1039-1050. http://dx.doi.org/10.1038/ncb1763
-
(2008)
Nat. Cell Biol.
, vol.10
, pp. 1039-1050
-
-
Choi, C.K.1
Vicente-Manzanares, M.2
Zareno, J.3
Whitmore, L.A.4
Mogilner, A.5
Horwitz, A.R.6
-
17
-
-
0029995797
-
Rho-stimulated contractility drives the formation of stress fibers and focal adhesions
-
Chrzanowska-Wodnicka, M., and K. Burridge. 1996. Rho-stimulated contractility drives the formation of stress fibers and focal adhesions. J. Cell Biol. 133:1403-1415. http://dx.doi.org/10.1083/jcb.133.6.1403
-
(1996)
J. Cell Biol.
, vol.133
, pp. 1403-1415
-
-
Chrzanowska-Wodnicka, M.1
Burridge, K.2
-
18
-
-
38449101120
-
Integration of biological networks and gene expression data using Cytoscape
-
Cline, M.S., M. Smoot, E. Cerami, A. Kuchinsky, N. Landys, C. Workman, R. Christmas, I. Avila-Campilo, M. Creech, B. Gross, et al. 2007. Integration of biological networks and gene expression data using Cytoscape. Nat. Protoc. 2:2366-2382. http://dx.doi.org/10.1038/nprot.2007.324
-
(2007)
Nat. Protoc.
, vol.2
, pp. 2366-2382
-
-
Cline, M.S.1
Smoot, M.2
Cerami, E.3
Kuchinsky, A.4
Landys, N.5
Workman, C.6
Christmas, R.7
Avila-Campilo, I.8
Creech, M.9
Gross, B.10
-
19
-
-
0034306450
-
Specificity and mechanism of action of some commonly used protein kinase inhibitors
-
Davies, S.P., H. Reddy, M. Caivano, and P. Cohen. 2000. Specificity and mechanism of action of some commonly used protein kinase inhibitors. Biochem. J. 351:95-105. http://dx.doi.org/10.1042/bj3510095
-
(2000)
Biochem. J.
, vol.351
, pp. 95-105
-
-
Davies, S.P.1
Reddy, H.2
Caivano, M.3
Cohen, P.4
-
20
-
-
84946782437
-
Local 3D matrix microenvironment regulates cell migration through spatiotemporal dynamics of contractility-dependent adhesions
-
Doyle, A.D., N. Carvajal, A. Jin, K. Matsumoto, and K.M. Yamada. 2015. Local 3D matrix microenvironment regulates cell migration through spatiotemporal dynamics of contractility-dependent adhesions. Nat. Commun. 6:8720. http://dx.doi.org/10.1038/ncomms9720
-
(2015)
Nat. Commun.
, vol.6
, pp. 8720
-
-
Doyle, A.D.1
Carvajal, N.2
Jin, A.3
Matsumoto, K.4
Yamada, K.M.5
-
21
-
-
76449110492
-
Focal adhesion kinase-dependent regulation of adhesive forces involves vinculin recruitment to focal adhesions
-
Dumbauld, D.W., K.E. Michael, S.K. Hanks, and A.J. García. 2010. Focal adhesion kinase-dependent regulation of adhesive forces involves vinculin recruitment to focal adhesions. Biol. Cell. 102:203-213. http://dx.doi.org/10.1042/BC20090104
-
(2010)
Biol. Cell.
, vol.102
, pp. 203-213
-
-
Dumbauld, D.W.1
Michael, K.E.2
Hanks, S.K.3
García, A.J.4
-
22
-
-
34249936024
-
Forces and bond dynamics in cell adhesion
-
Evans, E.A., and D.A. Calderwood. 2007. Forces and bond dynamics in cell adhesion. Science. 316:1148-1153. http://dx.doi.org/10.1126/science.1137592
-
(2007)
Science.
, vol.316
, pp. 1148-1153
-
-
Evans, E.A.1
Calderwood, D.A.2
-
23
-
-
20444370219
-
Microtubule-induced focal adhesion disassembly is mediated by dynamin and focal adhesion kinase
-
Ezratty, E.J., M.A. Partridge, and G.G. Gundersen. 2005. Microtubule-induced focal adhesion disassembly is mediated by dynamin and focal adhesion kinase. Nat. Cell Biol. 7:581-590. http://dx.doi.org/10.1038/ncb1262
-
(2005)
Nat. Cell Biol.
, vol.7
, pp. 581-590
-
-
Ezratty, E.J.1
Partridge, M.A.2
Gundersen, G.G.3
-
24
-
-
0029741102
-
Inhibition of focal adhesion kinase (FAK) signaling in focal adhesions decreases cell motility and proliferation
-
Gilmore, A.P., and L.H. Romer. 1996. Inhibition of focal adhesion kinase (FAK) signaling in focal adhesions decreases cell motility and proliferation. Mol. Biol. Cell. 7:1209-1224. http://dx.doi.org/10.1091/mbc.7.8.1209
-
(1996)
Mol. Biol. Cell.
, vol.7
, pp. 1209-1224
-
-
Gilmore, A.P.1
Romer, L.H.2
-
25
-
-
33750491945
-
N-(5-chloro-1,3-benzodioxol-4-yl)-7-[2-(4-methylpiperazin-1-yl)ethoxy]-5-(tetrahydro-2H-pyran-4-yloxy)quinazolin-4-amine, a novel, highly selective, orally available, dual-specific c-Src/Abl kinase inhibitor
-
Hennequin, L.F., J. Allen, J. Breed, J. Curwen, M. Fennell, T.P. Green, C. Lambertvan der Brempt, R. Morgentin, R.A. Norman, A. Olivier, et al. 2006. N-(5-chloro-1,3-benzodioxol-4-yl)-7-[2-(4-methylpiperazin-1-yl)ethoxy]-5-(tetrahydro-2H-pyran-4-yloxy)quinazolin-4-amine, a novel, highly selective, orally available, dual-specific c-Src/Abl kinase inhibitor. J. Med. Chem. 49:6465-6488. http://dx.doi.org/10.1021/jm060434q
-
(2006)
J. Med. Chem.
, vol.49
, pp. 6465-6488
-
-
Hennequin, L.F.1
Allen, J.2
Breed, J.3
Curwen, J.4
Fennell, M.5
Green, T.P.6
Lambertvan der Brempt, C.7
Morgentin, R.8
Norman, R.A.9
Olivier, A.10
-
26
-
-
84902665682
-
Symmetric exchange of multi-protein building blocks between stationary focal adhesions and the cytosol
-
Hoffmann, J.-E., Y. Fermin, R.L. Stricker, K. Ickstadt, and E. Zamir. 2014. Symmetric exchange of multi-protein building blocks between stationary focal adhesions and the cytosol. eLife. 3:e02257. http://dx.doi.org/10.7554/eLife.02257
-
(2014)
eLife.
, vol.3
, pp. e02257
-
-
Hoffmann, J.-E.1
Fermin, Y.2
Stricker, R.L.3
Ickstadt, K.4
Zamir, E.5
-
27
-
-
0002294347
-
A simple sequentially rejective multiple test procedure
-
Holm, S. 1979. A simple sequentially rejective multiple test procedure. Scand. J. Stat. 6:65-70.
-
(1979)
Scand. J. Stat.
, vol.6
, pp. 65-70
-
-
Holm, S.1
-
28
-
-
84948718179
-
Definition of a consensus integrin adhesome and its dynamics during adhesion complex assembly and disassembly
-
Horton, E.R., A. Byron, J.A. Askari, D.H.J. Ng, A. Millon-Frémillon, J. Robertson, E.J. Koper, N.R. Paul, S. Warwood, D. Knight, et al. 2015a. Definition of a consensus integrin adhesome and its dynamics during adhesion complex assembly and disassembly. Nat. Cell Biol. 17:1577-1587. http://dx.doi.org/10.1038/ncb3257
-
(2015)
Nat. Cell Biol.
, vol.17
, pp. 1577-1587
-
-
Horton, E.R.1
Byron, A.2
Askari, J.A.3
Ng, D.H.J.4
Millon-Frémillon, A.5
Robertson, J.6
Koper, E.J.7
Paul, N.R.8
Warwood, S.9
Knight, D.10
-
29
-
-
84964086217
-
Mechanosensitivity of integrin adhesion complexes: role of the consensus adhesome
-
Horton, E.R., P. Astudillo, M.J. Humphries, and J.D. Humphries. 2015b. Mechanosensitivity of integrin adhesion complexes: role of the consensus adhesome. Exp. Cell Res. http://dx.doi.org/S0014-4827(15)30130-0
-
(2015)
Exp. Cell Res.
-
-
Horton, E.R.1
Astudillo, P.2
Humphries, M.J.3
Humphries, J.D.4
-
30
-
-
84868019676
-
Integrin bi-directional signaling across the plasma membrane
-
Hu, P., and B.-H. Luo. 2013. Integrin bi-directional signaling across the plasma membrane. J. Cell. Physiol. 228:306-312. http://dx.doi.org/10.1002/jcp.24154
-
(2013)
J. Cell. Physiol.
, vol.228
, pp. 306-312
-
-
Hu, P.1
Luo, B.-H.2
-
31
-
-
84913609685
-
GEF-H1 controls focal adhesion signaling that regulates mesenchymal stem cell lineage commitment
-
Huang, I.H., C.T. Hsiao, J.C. Wu, R.F. Shen, C.Y. Liu, Y.K. Wang, Y.C. Chen, C.M. Huang, J.C. del Álamo, Z.F. Chang, et al. 2014. GEF-H1 controls focal adhesion signaling that regulates mesenchymal stem cell lineage commitment. J. Cell Sci. 127:4186-4200. http://dx.doi.org/10.1242/jcs.150227
-
(2014)
J. Cell Sci.
, vol.127
, pp. 4186-4200
-
-
Huang, I.H.1
Hsiao, C.T.2
Wu, J.C.3
Shen, R.F.4
Liu, C.Y.5
Wang, Y.K.6
Chen, Y.C.7
Huang, C.M.8
del Álamo, J.C.9
Chang, Z.F.10
-
32
-
-
36849069902
-
Vinculin controls focal adhesion formation by direct interactions with talin and actin
-
Humphries, J.D., P. Wang, C. Streuli, B. Geiger, M.J. Humphries, and C. Ballestrem. 2007. Vinculin controls focal adhesion formation by direct interactions with talin and actin. J. Cell Biol. 179:1043-1057. http://dx.doi.org/10.1083/jcb.200703036
-
(2007)
J. Cell Biol.
, vol.179
, pp. 1043-1057
-
-
Humphries, J.D.1
Wang, P.2
Streuli, C.3
Geiger, B.4
Humphries, M.J.5
Ballestrem, C.6
-
33
-
-
77951153298
-
Proteomic analysis of integrin-associated complexes identifies RCC2 as a dual regulator of Rac1 and Arf6
-
Humphries, J.D., A. Byron, M.D. Bass, S.E. Craig, J.W. Pinney, D. Knight, and M.J. Humphries. 2009. Proteomic analysis of integrin-associated complexes identifies RCC2 as a dual regulator of Rac1 and Arf6. Sci. Signal. 2:ra51. http://dx.doi.org/10.1126/scisignal.2000396
-
(2009)
Sci. Signal.
, vol.2
, pp. ra51
-
-
Humphries, J.D.1
Byron, A.2
Bass, M.D.3
Craig, S.E.4
Pinney, J.W.5
Knight, D.6
Humphries, M.J.7
-
34
-
-
84937631806
-
Emerging properties of adhesion complexes: what are they and what do they do?
-
Humphries, J.D., N.R. Paul, M.J. Humphries, and M.R. Morgan. 2015. Emerging properties of adhesion complexes: what are they and what do they do? Trends Cell Biol. 25:388-397. http://dx.doi.org/10.1016/j.tcb.2015.02.008
-
(2015)
Trends Cell Biol.
, vol.25
, pp. 388-397
-
-
Humphries, J.D.1
Paul, N.R.2
Humphries, M.J.3
Morgan, M.R.4
-
35
-
-
0029120440
-
Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice
-
Ilić, D., Y. Furuta, S. Kanazawa, N. Takeda, K. Sobue, N. Nakatsuji, S. Nomura, J. Fujimoto, M. Okada, and T. Yamamoto. 1995. Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice. Nature. 377:539-544. http://dx.doi.org/10.1038/377539a0
-
(1995)
Nature.
, vol.377
, pp. 539-544
-
-
Ilić, D.1
Furuta, Y.2
Kanazawa, S.3
Takeda, N.4
Sobue, K.5
Nakatsuji, N.6
Nomura, S.7
Fujimoto, J.8
Okada, M.9
Yamamoto, T.10
-
36
-
-
0033864069
-
Y-27632, an inhibitor of rho-associated protein kinase, suppresses tumor cell invasion via regulation of focal adhesion and focal adhesion kinase
-
Imamura, F., M. Mukai, M. Ayaki, and H. Akedo. 2000. Y-27632, an inhibitor of rho-associated protein kinase, suppresses tumor cell invasion via regulation of focal adhesion and focal adhesion kinase. Jpn. J. Cancer Res. 91:811-816. http://dx.doi.org/10.1111/j.1349-7006.2000.tb01018.x
-
(2000)
Jpn. J. Cancer Res.
, vol.91
, pp. 811-816
-
-
Imamura, F.1
Mukai, M.2
Ayaki, M.3
Akedo, H.4
-
37
-
-
84902455490
-
The inhibition of SRC family kinase suppresses pancreatic cancer cell proliferation, migration, and invasion
-
Je, D.W., Y.M. O, Y.G. Ji, Y. Cho, and D.H. Lee. 2014. The inhibition of SRC family kinase suppresses pancreatic cancer cell proliferation, migration, and invasion. Pancreas. 43:768-776. http://dx.doi.org/10.1097/MPA.0000000000000103
-
(2014)
Pancreas.
, vol.43
, pp. 768-776
-
-
Je, D.W.1
Oh, Y.M.2
Ji, Y.G.3
Cho, Y.4
Lee, D.H.5
-
38
-
-
84948718023
-
Isolation of integrin-based adhesion complexes
-
9.8.1-9.8
-
Jones, M.C., J.D. Humphries, A. Byron, A. Millon-Frémillon, J. Robertson, N.R. Paul, D.H.J. Ng, J.A. Askari, and M.J. Humphries. 2015. Isolation of integrin-based adhesion complexes. Curr. Protoc. Cell Biol. 66:9.8.1-9.8: 15. http://dx.doi.org/10.1002/0471143030.cb0908s66
-
(2015)
Curr. Protoc. Cell Biol.
, vol.66
, pp. 15
-
-
Jones, M.C.1
Humphries, J.D.2
Byron, A.3
Millon-Frémillon, A.4
Robertson, J.5
Paul, N.R.6
Ng, D.H.J.7
Askari, J.A.8
Humphries, M.J.9
-
39
-
-
0036178447
-
Signal transduction by cell adhesion receptors and the cytoskeleton: functions of integrins, cadherins, selectins, and immunoglobulin-superfamily members
-
Juliano, R.L. 2002. Signal transduction by cell adhesion receptors and the cytoskeleton: functions of integrins, cadherins, selectins, and immunoglobulin-superfamily members. Annu. Rev. Pharmacol. Toxicol. 42:283-323. http://dx.doi.org/10.1146/annurev.pharmtox.42.090401.151133
-
(2002)
Annu. Rev. Pharmacol. Toxicol.
, vol.42
, pp. 283-323
-
-
Juliano, R.L.1
-
40
-
-
70349758510
-
Src kinases as therapeutic targets for cancer
-
Kim, L.C., L. Song, and E.B. Haura. 2009. Src kinases as therapeutic targets for cancer. Nat. Rev. Clin. Oncol. 6:587-595. http://dx.doi.org/10.1038/nrclinonc.2009.129
-
(2009)
Nat. Rev. Clin. Oncol.
, vol.6
, pp. 587-595
-
-
Kim, L.C.1
Song, L.2
Haura, E.B.3
-
41
-
-
0037444481
-
Live-cell monitoring of tyrosine phosphorylation in focal adhesions following microtubule disruption
-
Kirchner, J., Z. Kam, G. Tzur, A.D. Bershadsky, and B. Geiger. 2003. Live-cell monitoring of tyrosine phosphorylation in focal adhesions following microtubule disruption. J. Cell Sci. 116:975-986. http://dx.doi.org/10.1242/jcs.00284
-
(2003)
J. Cell Sci.
, vol.116
, pp. 975-986
-
-
Kirchner, J.1
Kam, Z.2
Tzur, G.3
Bershadsky, A.D.4
Geiger, B.5
-
42
-
-
0027055575
-
Cell adhesion or integrin clustering increases phosphorylation of a focal adhesion-associated tyrosine kinase
-
Kornberg, L., H.S. Earp, J.T. Parsons, M. Schaller, and R.L. Juliano. 1992. Cell adhesion or integrin clustering increases phosphorylation of a focal adhesion-associated tyrosine kinase. J. Biol. Chem. 267:23439-23442.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 23439-23442
-
-
Kornberg, L.1
Earp, H.S.2
Parsons, J.T.3
Schaller, M.4
Juliano, R.L.5
-
43
-
-
79953303384
-
Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation
-
Kuo, J.C., X. Han, C.T. Hsiao, J.R. Yates III, and C.M. Waterman. 2011. Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation. Nat. Cell Biol. 13:383-393. http://dx.doi.org/10.1038/ncb2216
-
(2011)
Nat. Cell Biol.
, vol.13
, pp. 383-393
-
-
Kuo, J.C.1
Han, X.2
Hsiao, C.T.3
Yates, J.R.4
Waterman, C.M.5
-
44
-
-
80054738639
-
Isolation of focal adhesion proteins for biochemical and proteomic analysis
-
Kuo, J.C., X. Han, J.R. Yates III, and C.M. Waterman. 2012. Isolation of focal adhesion proteins for biochemical and proteomic analysis. Methods Mol. Biol. 757:297-323. http://dx.doi.org/10.1007/978-1-61779-166-6_19
-
(2012)
Methods Mol. Biol.
, vol.757
, pp. 297-323
-
-
Kuo, J.C.1
Han, X.2
Yates, J.R.3
Waterman, C.M.4
-
45
-
-
84863041492
-
FAK promotes recruitment of talin to nascent adhesions to control cell motility
-
Lawson, C., S.T. Lim, S. Uryu, X.L. Chen, D.A. Calderwood, and D.D. Schlaepfer. 2012. FAK promotes recruitment of talin to nascent adhesions to control cell motility. J. Cell Biol. 196:223-232. http://dx.doi.org/10.1083/jcb.201108078
-
(2012)
J. Cell Biol.
, vol.196
, pp. 223-232
-
-
Lawson, C.1
Lim, S.T.2
Uryu, S.3
Chen, X.L.4
Calderwood, D.A.5
Schlaepfer, D.D.6
-
46
-
-
84883485436
-
Distinct FAK activities determine progenitor and mammary stem cell characteristics
-
Luo, M., X. Zhao, S. Chen, S. Liu, M.S. Wicha, and J.L. Guan. 2013. Distinct FAK activities determine progenitor and mammary stem cell characteristics. Cancer Res. 73:5591-5602. http://dx.doi.org/10.1158/0008-5472.CAN-13-1351
-
(2013)
Cancer Res.
, vol.73
, pp. 5591-5602
-
-
Luo, M.1
Zhao, X.2
Chen, S.3
Liu, S.4
Wicha, M.S.5
Guan, J.L.6
-
47
-
-
84927965477
-
The many faces of cell adhesion during Drosophila muscle development
-
Maartens, A.P., and N.H. Brown. 2015. The many faces of cell adhesion during Drosophila muscle development. Dev. Biol. 401:62-74. http://dx.doi.org/10.1016/j.ydbio.2014.12.038
-
(2015)
Dev. Biol.
, vol.401
, pp. 62-74
-
-
Maartens, A.P.1
Brown, N.H.2
-
48
-
-
84855958004
-
Methods for cell and particle tracking
-
Meijering, E., O. Dzyubachyk, and I. Smal. 2012. Methods for cell and particle tracking. Methods Enzymol. 504:183-200. http://dx.doi.org/10.1016/B978-0-12-391857-4.00009-4
-
(2012)
Methods Enzymol.
, vol.504
, pp. 183-200
-
-
Meijering, E.1
Dzyubachyk, O.2
Smal, I.3
-
49
-
-
84946074739
-
The InterPro protein families database: the classification resource after 15 years
-
Mitchell, A., H.Y. Chang, L. Daugherty, M. Fraser, S. Hunter, R. Lopez, C. McAnulla, C. McMenamin, G. Nuka, S. Pesseat, et al. 2015. The InterPro protein families database: the classification resource after 15 years. Nucleic Acids Res. 43:D213-D221. http://dx.doi.org/10.1093/nar/gku1243
-
(2015)
Nucleic Acids Res.
, vol.43
, pp. D213-D221
-
-
Mitchell, A.1
Chang, H.Y.2
Daugherty, L.3
Fraser, M.4
Hunter, S.5
Lopez, R.6
McAnulla, C.7
McMenamin, C.8
Nuka, G.9
Pesseat, S.10
-
50
-
-
33748286819
-
Integrin-regulated FAK-Src signaling in normal and cancer cells
-
Mitra, S.K., and D.D. Schlaepfer. 2006. Integrin-regulated FAK-Src signaling in normal and cancer cells. Curr. Opin. Cell Biol. 18:516-523. http://dx.doi.org/10.1016/j.ceb.2006.08.011
-
(2006)
Curr. Opin. Cell Biol.
, vol.18
, pp. 516-523
-
-
Mitra, S.K.1
Schlaepfer, D.D.2
-
51
-
-
36448970493
-
Synergistic control of cell adhesion by integrins and syndecans
-
Morgan, M.R., M.J. Humphries, and M.D. Bass. 2007. Synergistic control of cell adhesion by integrins and syndecans. Nat. Rev. Mol. Cell Biol. 8:957-969. http://dx.doi.org/10.1038/nrm2289
-
(2007)
Nat. Rev. Mol. Cell Biol.
, vol.8
, pp. 957-969
-
-
Morgan, M.R.1
Humphries, M.J.2
Bass, M.D.3
-
52
-
-
33748983217
-
Expression of FAKrelated non-kinase (FRNK) coincides with morphological change in the early stage of cell adhesion
-
Nagoshi, Y., G. Yamamoto, T. Irie, and T. Tachikawa. 2006. Expression of FAKrelated non-kinase (FRNK) coincides with morphological change in the early stage of cell adhesion. Med. Mol. Morphol. 39:154-160. http://dx.doi.org/10.1007/s00795-006-0325-8
-
(2006)
Med. Mol. Morphol.
, vol.39
, pp. 154-160
-
-
Nagoshi, Y.1
Yamamoto, G.2
Irie, T.3
Tachikawa, T.4
-
53
-
-
84919493073
-
Microtubule-dependent modulation of adhesion complex composition
-
Ng, D.H.J., J.D. Humphries, A. Byron, A. Millon-Frémillon, and M.J. Humphries. 2014. Microtubule-dependent modulation of adhesion complex composition. PLoS One. 9:e115213. http://dx.doi.org/10.1371/journal.pone.0115213
-
(2014)
PLoS One.
, vol.9
, pp. e115213
-
-
Ng, D.H.J.1
Humphries, J.D.2
Byron, A.3
Millon-Frémillon, A.4
Humphries, M.J.5
-
54
-
-
84859387007
-
Tension is required but not sufficient for focal adhesion maturation without a stress fiber template
-
Oakes, P.W., Y. Beckham, J. Stricker, and M.L. Gardel. 2012. Tension is required but not sufficient for focal adhesion maturation without a stress fiber template. J. Cell Biol. 196:363-374. http://dx.doi.org/10.1083/jcb.201107042
-
(2012)
J. Cell Biol.
, vol.196
, pp. 363-374
-
-
Oakes, P.W.1
Beckham, Y.2
Stricker, J.3
Gardel, M.L.4
-
55
-
-
77949754056
-
Myosin II activity regulates vinculin recruitment to focal adhesions through FAK-mediated paxillin phosphorylation
-
Pasapera, A.M., I.C. Schneider, E. Rericha, D.D. Schlaepfer, and C.M. Waterman. 2010. Myosin II activity regulates vinculin recruitment to focal adhesions through FAK-mediated paxillin phosphorylation. J. Cell Biol. 188:877-890. http://dx.doi.org/10.1083/jcb.200906012
-
(2010)
J. Cell Biol.
, vol.188
, pp. 877-890
-
-
Pasapera, A.M.1
Schneider, I.C.2
Rericha, E.3
Schlaepfer, D.D.4
Waterman, C.M.5
-
56
-
-
0033434080
-
Probabilitybased protein identification by searching sequence databases using mass spectrometry data
-
Perkins, D.N., D.J. Pappin, D.M. Creasy, and J.S. Cottrell. 1999. Probabilitybased protein identification by searching sequence databases using mass spectrometry data. Electrophoresis. 20:3551-3567. http://dx.doi.org/10.1002/(SICI)1522-2683(19991201)20:18<3551::AID-ELPS3551>3.0.CO;2-2
-
(1999)
Electrophoresis.
, vol.20
, pp. 3551-3567
-
-
Perkins, D.N.1
Pappin, D.J.2
Creasy, D.M.3
Cottrell, J.S.4
-
57
-
-
0842304432
-
Discovery of a new class of anilinoquinazoline inhibitors with high affinity and specificity for the tyrosine kinase domain of c-Src
-
Plé, P.A., T.P. Green, L.F. Hennequin, J. Curwen, M. Fennell, J. Allen, C. Lambert-Van Der Brempt, and G. Costello. 2004. Discovery of a new class of anilinoquinazoline inhibitors with high affinity and specificity for the tyrosine kinase domain of c-Src. J. Med. Chem. 47:871-887. http://dx.doi.org/10.1021/jm030317k
-
(2004)
J. Med. Chem.
, vol.47
, pp. 871-887
-
-
Plé, P.A.1
Green, T.P.2
Hennequin, L.F.3
Curwen, J.4
Fennell, M.5
Allen, J.6
Lambert-Van Der Brempt, C.7
Costello, G.8
-
58
-
-
84871591464
-
Force fluctuations within focal adhesions mediate ECM-rigidity sensing to guide directed cell migration
-
Plotnikov, S.V., A.M. Pasapera, B. Sabass, and C.M. Waterman. 2012. Force fluctuations within focal adhesions mediate ECM-rigidity sensing to guide directed cell migration. Cell. 151:1513-1527. http://dx.doi.org/10.1016/j.cell.2012.11.034
-
(2012)
Cell.
, vol.151
, pp. 1513-1527
-
-
Plotnikov, S.V.1
Pasapera, A.M.2
Sabass, B.3
Waterman, C.M.4
-
59
-
-
0033731010
-
Focal adhesion kinase suppresses Rho activity to promote focal adhesion turnover
-
Ren, X.D., W.B. Kiosses, D.J. Sieg, C.A. Otey, D.D. Schlaepfer, and M.A. Schwartz. 2000. Focal adhesion kinase suppresses Rho activity to promote focal adhesion turnover. J. Cell Sci. 113:3673-3678.
-
(2000)
J. Cell Sci.
, vol.113
, pp. 3673-3678
-
-
Ren, X.D.1
Kiosses, W.B.2
Sieg, D.J.3
Otey, C.A.4
Schlaepfer, D.D.5
Schwartz, M.A.6
-
60
-
-
0029971297
-
A mechanism for regulation of the adhesion-associated proteintyrosine kinase pp125FAK
-
Richardson, A., and T. Parsons. 1996. A mechanism for regulation of the adhesion-associated proteintyrosine kinase pp125FAK. Nature. 380:538-540. http://dx.doi.org/10.1038/380538a0
-
(1996)
Nature.
, vol.380
, pp. 538-540
-
-
Richardson, A.1
Parsons, T.2
-
61
-
-
0030694182
-
Inhibition of cell spreading by expression of the C-terminal domain of focal adhesion kinase (FAK) is rescued by coexpression of Src or catalytically inactive FAK: a role for paxillin tyrosine phosphorylation
-
Richardson, A., R.K. Malik, J.D. Hildebrand, and J.T. Parsons. 1997. Inhibition of cell spreading by expression of the C-terminal domain of focal adhesion kinase (FAK) is rescued by coexpression of Src or catalytically inactive FAK: a role for paxillin tyrosine phosphorylation. Mol. Cell. Biol. 17:6906-6914. http://dx.doi.org/10.1128/MCB.17.12.6906
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 6906-6914
-
-
Richardson, A.1
Malik, R.K.2
Hildebrand, J.D.3
Parsons, J.T.4
-
62
-
-
84937630834
-
Defining the phospho-adhesome through the phosphoproteomic analysis of integrin signalling
-
Robertson, J., G. Jacquemet, A. Byron, M.C. Jones, S. Warwood, J.N. Selley, D. Knight, J.D. Humphries, and M.J. Humphries. 2015. Defining the phospho-adhesome through the phosphoproteomic analysis of integrin signalling. Nat. Commun. 6:6265. http://dx.doi.org/10.1038/ncomms7265
-
(2015)
Nat. Commun.
, vol.6
, pp. 6265
-
-
Robertson, J.1
Jacquemet, G.2
Byron, A.3
Jones, M.C.4
Warwood, S.5
Selley, J.N.6
Knight, D.7
Humphries, J.D.8
Humphries, M.J.9
-
63
-
-
84859039080
-
Src kinases catalytic activity regulates proliferation, migration and invasiveness of MDA-MB-231 breast cancer cells
-
Sánchez-Bailón, M.P., A. Calcabrini, D. Gómez-Domínguez, B. Morte, E. Martín-Forero, G. Gómez-López, A. Molinari, K.U. Wagner, and J. Martín-Pérez. 2012. Src kinases catalytic activity regulates proliferation, migration and invasiveness of MDA-MB-231 breast cancer cells. Cell. Signal. 24:1276-1286. http://dx.doi.org/10.1016/j.cellsig.2012.02.011
-
(2012)
Cell. Signal.
, vol.24
, pp. 1276-1286
-
-
Sánchez-Bailón, M.P.1
Calcabrini, A.2
Gómez-Domínguez, D.3
Morte, B.4
Martín-Forero, E.5
Gómez-López, G.6
Molinari, A.7
Wagner, K.U.8
Martín-Pérez, J.9
-
64
-
-
0028986116
-
pp125FAK-dependent tyrosine phosphorylation of paxillin creates a high-affinity binding site for Crk
-
Schaller, M.D., and J.T. Parsons. 1995. pp125FAK-dependent tyrosine phosphorylation of paxillin creates a high-affinity binding site for Crk. Mol. Cell. Biol. 15:2635-2645. http://dx.doi.org/10.1128/MCB.15.5.2635
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 2635-2645
-
-
Schaller, M.D.1
Parsons, J.T.2
-
65
-
-
0026612521
-
pp125FAK a structurally distinctive protein-tyrosine kinase associated with focal adhesions
-
Schaller, M.D., C.A. Borgman, B.S. Cobb, R.R. Vines, A.B. Reynolds, and J.T. Parsons. 1992. pp125FAK a structurally distinctive protein-tyrosine kinase associated with focal adhesions. Proc. Natl. Acad. Sci. USA. 89:5192-5196. http://dx.doi.org/10.1073/pnas.89.11.5192
-
(1992)
Proc. Natl. Acad. Sci. USA.
, vol.89
, pp. 5192-5196
-
-
Schaller, M.D.1
Borgman, C.A.2
Cobb, B.S.3
Vines, R.R.4
Reynolds, A.B.5
Parsons, J.T.6
-
66
-
-
0028350859
-
Autophosphorylation of the focal adhesion kinase, pp125FAK, directs SH2-dependent binding of pp60src
-
Schaller, M.D., J.D. Hildebrand, J.D. Shannon, J.W. Fox, R.R. Vines, and J.T. Parsons. 1994. Autophosphorylation of the focal adhesion kinase, pp125FAK, directs SH2-dependent binding of pp60src. Mol. Cell. Biol. 14:1680-1688. http://dx.doi.org/10.1128/MCB.14.3.1680
-
(1994)
Mol. Cell. Biol.
, vol.14
, pp. 1680-1688
-
-
Schaller, M.D.1
Hildebrand, J.D.2
Shannon, J.D.3
Fox, J.W.4
Vines, R.R.5
Parsons, J.T.6
-
67
-
-
79952283069
-
Quantitative proteomics of the integrin adhesome show a myosin II-dependent recruitment of LIM domain proteins
-
Schiller, H.B., C.C. Friedel, C. Boulegue, and R. Fässler. 2011. Quantitative proteomics of the integrin adhesome show a myosin II-dependent recruitment of LIM domain proteins. EMBO Rep. 12:259-266. http://dx.doi.org/10.1038/embor.2011.5
-
(2011)
EMBO Rep.
, vol.12
, pp. 259-266
-
-
Schiller, H.B.1
Friedel, C.C.2
Boulegue, C.3
Fässler, R.4
-
68
-
-
84878598076
-
β1-and αv-class integrins cooperate to regulate myosin II during rigidity sensing of fibronectin-based microenvironments
-
Schiller, H.B., M.R. Hermann, J. Polleux, T. Vignaud, S. Zanivan, C.C. Friedel, Z. Sun, A. Raducanu, K.-E. Gottschalk, M. Théry, et al. 2013. β1-and αv-class integrins cooperate to regulate myosin II during rigidity sensing of fibronectin-based microenvironments. Nat. Cell Biol. 15:625-636. http://dx.doi.org/10.1038/ncb2747
-
(2013)
Nat. Cell Biol.
, vol.15
, pp. 625-636
-
-
Schiller, H.B.1
Hermann, M.R.2
Polleux, J.3
Vignaud, T.4
Zanivan, S.5
Friedel, C.C.6
Sun, Z.7
Raducanu, A.8
Gottschalk, K.-E.9
Théry, M.10
-
69
-
-
84862520770
-
Fiji: an opensource platform for biological-image analysis
-
Schindelin, J., I. Arganda-Carreras, E. Frise, V. Kaynig, M. Longair, T. Pietzsch, S. Preibisch, C. Rueden, S. Saalfeld, B. Schmid, et al. 2012. Fiji: an opensource platform for biological-image analysis. Nat. Methods. 9:676-682. http://dx.doi.org/10.1038/nmeth.2019
-
(2012)
Nat. Methods.
, vol.9
, pp. 676-682
-
-
Schindelin, J.1
Arganda-Carreras, I.2
Frise, E.3
Kaynig, V.4
Longair, M.5
Pietzsch, T.6
Preibisch, S.7
Rueden, C.8
Saalfeld, S.9
Schmid, B.10
-
70
-
-
33847413148
-
Focal adhesion kinase modulates tension signaling to control actin and focal adhesion dynamics
-
Schober, M., S. Raghavan, M. Nikolova, L. Polak, H.A. Pasolli, H.E. Beggs, L.F. Reichardt, and E. Fuchs. 2007. Focal adhesion kinase modulates tension signaling to control actin and focal adhesion dynamics. J. Cell Biol. 176:667-680. http://dx.doi.org/10.1083/jcb.200608010
-
(2007)
J. Cell Biol.
, vol.176
, pp. 667-680
-
-
Schober, M.1
Raghavan, S.2
Nikolova, M.3
Polak, L.4
Pasolli, H.A.5
Beggs, H.E.6
Reichardt, L.F.7
Fuchs, E.8
-
71
-
-
33846241683
-
Identification of potential biomarkers for measuring inhibition of Src kinase activity in colon cancer cells following treatment with dasatinib
-
Serrels, A., I.R.J. Macpherson, T.R.J. Evans, F.Y. Lee, E.A. Clark, O.J. Sansom, G.H. Ashton, M.C. Frame, and V.G. Brunton. 2006. Identification of potential biomarkers for measuring inhibition of Src kinase activity in colon cancer cells following treatment with dasatinib. Mol. Cancer Ther. 5:3014-3022. http://dx.doi.org/10.1158/1535-7163.MCT-06-0382
-
(2006)
Mol. Cancer Ther.
, vol.5
, pp. 3014-3022
-
-
Serrels, A.1
Macpherson, I.R.J.2
Evans, T.R.J.3
Lee, F.Y.4
Clark, E.A.5
Sansom, O.J.6
Ashton, G.H.7
Frame, M.C.8
Brunton, V.G.9
-
72
-
-
84861637416
-
The role of focal adhesion kinase catalytic activity on the proliferation and migration of squamous cell carcinoma cells
-
Serrels, A., K. McLeod, M. Canel, A. Kinnaird, K. Graham, M.C. Frame, and V.G. Brunton. 2012. The role of focal adhesion kinase catalytic activity on the proliferation and migration of squamous cell carcinoma cells. Int. J. Cancer. 131:287-297. http://dx.doi.org/10.1002/ijc.26351
-
(2012)
Int. J. Cancer.
, vol.131
, pp. 287-297
-
-
Serrels, A.1
McLeod, K.2
Canel, M.3
Kinnaird, A.4
Graham, K.5
Frame, M.C.6
Brunton, V.G.7
-
73
-
-
0029927505
-
Mass spectrometric sequencing of proteins silver-stained polyacrylamide gels
-
Shevchenko, A., M. Wilm, O. Vorm, and M. Mann. 1996. Mass spectrometric sequencing of proteins silver-stained polyacrylamide gels. Anal. Chem. 68:850-858. http://dx.doi.org/10.1021/ac950914h
-
(1996)
Anal. Chem.
, vol.68
, pp. 850-858
-
-
Shevchenko, A.1
Wilm, M.2
Vorm, O.3
Mann, M.4
-
74
-
-
0032531732
-
Pyk2 and Src-family protein-tyrosine kinases compensate for the loss of FAK in fibronectin-stimulated signaling events but Pyk2 does not fully function to enhance FAK-cell migration
-
Sieg, D.J., D. Ilić, K.C. Jones, C.H. Damsky, T. Hunter, and D.D. Schlaepfer. 1998. Pyk2 and Src-family protein-tyrosine kinases compensate for the loss of FAK in fibronectin-stimulated signaling events but Pyk2 does not fully function to enhance FAK-cell migration. EMBO J. 17:5933-5947. http://dx.doi.org/10.1093/emboj/17.20.5933
-
(1998)
EMBO J.
, vol.17
, pp. 5933-5947
-
-
Sieg, D.J.1
Ilić, D.2
Jones, K.C.3
Damsky, C.H.4
Hunter, T.5
Schlaepfer, D.D.6
-
75
-
-
0032820782
-
Required role of focal adhesion kinase (FAK) for integrin-stimulated cell migration
-
Sieg, D.J., C.R. Hauck, and D.D. Schlaepfer. 1999. Required role of focal adhesion kinase (FAK) for integrin-stimulated cell migration. J. Cell Sci. 112:2677-2691.
-
(1999)
J. Cell Sci.
, vol.112
, pp. 2677-2691
-
-
Sieg, D.J.1
Hauck, C.R.2
Schlaepfer, D.D.3
-
76
-
-
0033772308
-
FAK integrates growth-factor and integrin signals to promote cell migration
-
Sieg, D.J., C.R. Hauck, D. Ilić, C.K. Klingbeil, E. Schaefer, C.H. Damsky, and D.D. Schlaepfer. 2000. FAK integrates growth-factor and integrin signals to promote cell migration. Nat. Cell Biol. 2:249-256. http://dx.doi.org/10.1038/35010517
-
(2000)
Nat. Cell Biol.
, vol.2
, pp. 249-256
-
-
Sieg, D.J.1
Hauck, C.R.2
Ilić, D.3
Klingbeil, C.K.4
Schaefer, E.5
Damsky, C.H.6
Schlaepfer, D.D.7
-
77
-
-
0035826165
-
Alterations in the focal adhesion kinase/Src signal transduction pathway correlate with increased migratory capacity of prostate carcinoma cells
-
Slack, J.K., R.B. Adams, J.D. Rovin, E.A. Bissonette, C.E. Stoker, and J.T. Parsons. 2001. Alterations in the focal adhesion kinase/Src signal transduction pathway correlate with increased migratory capacity of prostate carcinoma cells. Oncogene. 20:1152-1163. http://dx.doi.org/10.1038/sj.onc.1204208
-
(2001)
Oncogene.
, vol.20
, pp. 1152-1163
-
-
Slack, J.K.1
Adams, R.B.2
Rovin, J.D.3
Bissonette, E.A.4
Stoker, C.E.5
Parsons, J.T.6
-
78
-
-
34447538483
-
Cellular characterization of a novel focal adhesion kinase inhibitor
-
Slack-Davis, J.K., K.H. Martin, R.W. Tilghman, M. Iwanicki, E.J. Ung, C. Autry, M.J. Luzzio, B. Cooper, J.C. Kath, W.G. Roberts, and J.T. Parsons. 2007. Cellular characterization of a novel focal adhesion kinase inhibitor. J. Biol. Chem. 282:14845-14852. http://dx.doi.org/10.1074/jbc. M606695200
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 14845-14852
-
-
Slack-Davis, J.K.1
Martin, K.H.2
Tilghman, R.W.3
Iwanicki, M.4
Ung, E.J.5
Autry, C.6
Luzzio, M.J.7
Cooper, B.8
Kath, J.C.9
Roberts, W.G.10
Parsons, J.T.11
-
79
-
-
81055127013
-
Inhibition of focal adhesion kinase by PF-562,271 inhibits the growth and metastasis of pancreatic cancer concomitant with altering the tumor microenvironment
-
Stokes, J.B., S.J. Adair, J.K. Slack-Davis, D.M. Walters, R.W. Tilghman, E.D. Hershey, B. Lowrey, K.S. Thomas, A.H. Bouton, R.F. Hwang, et al. 2011. Inhibition of focal adhesion kinase by PF-562,271 inhibits the growth and metastasis of pancreatic cancer concomitant with altering the tumor microenvironment. Mol. Cancer Ther. 10:2135-2145. http://dx.doi.org/10.1158/1535-7163.MCT-11-0261
-
(2011)
Mol. Cancer Ther.
, vol.10
, pp. 2135-2145
-
-
Stokes, J.B.1
Adair, S.J.2
Slack-Davis, J.K.3
Walters, D.M.4
Tilghman, R.W.5
Hershey, E.D.6
Lowrey, B.7
Thomas, K.S.8
Bouton, A.H.9
Hwang, R.F.10
-
80
-
-
84906935511
-
FAK in cancer: mechanistic findings and clinical applications
-
Sulzmaier, F.J., C. Jean, and D.D. Schlaepfer. 2014. FAK in cancer: mechanistic findings and clinical applications. Nat. Rev. Cancer. 14:598-610. http://dx.doi.org/10.1038/nrc3792
-
(2014)
Nat. Rev. Cancer.
, vol.14
, pp. 598-610
-
-
Sulzmaier, F.J.1
Jean, C.2
Schlaepfer, D.D.3
-
81
-
-
77953709612
-
PND-1186 FAK inhibitor selectively promotes tumor cell apoptosis in three-dimensional environments
-
Tanjoni, I., C. Walsh, S. Uryu, A. Tomar, J.-O. Nam, A. Mielgo, S.-T. Lim, C. Liang, M. Koenig, C. Sun, et al. 2010. PND-1186 FAK inhibitor selectively promotes tumor cell apoptosis in three-dimensional environments. Cancer Biol. Ther. 9:764-777. http://dx.doi.org/10.4161/cbt.9.10.11434
-
(2010)
Cancer Biol. Ther.
, vol.9
, pp. 764-777
-
-
Tanjoni, I.1
Walsh, C.2
Uryu, S.3
Tomar, A.4
Nam, J.-O.5
Mielgo, A.6
Lim, S.-T.7
Liang, C.8
Koenig, M.9
Sun, C.10
-
82
-
-
84874762979
-
The PRoteomics IDEntifications (PRIDE) database and associated tools: status in 2013
-
Vizcaíno, J.A., R.G. Côté, A. Csordas, J.A. Dianes, A. Fabregat, J.M. Foster, J. Griss, E. Alpi, M. Birim, J. Contell, et al. 2013. The PRoteomics IDEntifications (PRIDE) database and associated tools: status in 2013. Nucleic Acids Res. 41:D1063-D1069. http://dx.doi.org/10.1093/nar/gks1262
-
(2013)
Nucleic Acids Res.
, vol.41
, pp. D1063-D1069
-
-
Vizcaíno, J.A.1
Côté, R.G.2
Csordas, A.3
Dianes, J.A.4
Fabregat, A.5
Foster, J.M.6
Griss, J.7
Alpi, E.8
Birim, M.9
Contell, J.10
-
83
-
-
0029888132
-
Regulation of leukocyte adhesion and signaling in inflammation and disease
-
Wahl, S.M., G.M. Feldman, and J.B. McCarthy. 1996. Regulation of leukocyte adhesion and signaling in inflammation and disease. J. Leukoc. Biol. 59:789-796.
-
(1996)
J. Leukoc. Biol.
, vol.59
, pp. 789-796
-
-
Wahl, S.M.1
Feldman, G.M.2
McCarthy, J.B.3
-
84
-
-
0035949694
-
Focal adhesion kinase is involved in mechanosensing during fibroblast migration
-
Wang, H.B., M. Dembo, S.K. Hanks, and Y. Wang. 2001. Focal adhesion kinase is involved in mechanosensing during fibroblast migration. Proc. Natl. Acad. Sci. USA. 98:11295-11300. http://dx.doi.org/10.1073/pnas.201201198
-
(2001)
Proc. Natl. Acad. Sci. USA.
, vol.98
, pp. 11295-11300
-
-
Wang, H.B.1
Dembo, M.2
Hanks, S.K.3
Wang, Y.4
-
85
-
-
1642586962
-
FAK-Src signalling through paxillin, ERK and MLCK regulates adhesion disassembly
-
Webb, D.J., K. Donais, L.A. Whitmore, S.M. Thomas, C.E. Turner, J.T. Parsons, and A.F. Horwitz. 2004. FAK-Src signalling through paxillin, ERK and MLCK regulates adhesion disassembly. Nat. Cell Biol. 6:154-161. http://dx.doi.org/10.1038/ncb1094
-
(2004)
Nat. Cell Biol.
, vol.6
, pp. 154-161
-
-
Webb, D.J.1
Donais, K.2
Whitmore, L.A.3
Thomas, S.M.4
Turner, C.E.5
Parsons, J.T.6
Horwitz, A.F.7
-
86
-
-
4444338326
-
SRC-mediated phosphorylation of focal adhesion kinase couples actin and adhesion dynamics to survival signaling
-
Westhoff, M.A., B. Serrels, V.J. Fincham, M.C. Frame, and N.O. Carragher. 2004. SRC-mediated phosphorylation of focal adhesion kinase couples actin and adhesion dynamics to survival signaling. Mol. Cell. Biol. 24:8113-8133. http://dx.doi.org/10.1128/MCB.24.18.8113-8133.2004
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 8113-8133
-
-
Westhoff, M.A.1
Serrels, B.2
Fincham, V.J.3
Frame, M.C.4
Carragher, N.O.5
-
87
-
-
84896911248
-
The integrin adhesome: from genes and proteins to human disease
-
Winograd-Katz, S.E., R. Fässler, B. Geiger, and K.R. Legate. 2014. The integrin adhesome: from genes and proteins to human disease. Nat. Rev. Mol. Cell Biol. 15:273-288. http://dx.doi.org/10.1038/nrm3769
-
(2014)
Nat. Rev. Mol. Cell Biol.
, vol.15
, pp. 273-288
-
-
Winograd-Katz, S.E.1
Fässler, R.2
Geiger, B.3
Legate, K.R.4
-
88
-
-
58149271021
-
Integrated network analysis platform for protein-protein interactions
-
Wu, J., T. Vallenius, K. Ovaska, J. Westermarck, T.P. Mäkelä, and S. Hautaniemi. 2009. Integrated network analysis platform for protein-protein interactions. Nat. Methods. 6:75-77. http://dx.doi.org/10.1038/nmeth.1282
-
(2009)
Nat. Methods.
, vol.6
, pp. 75-77
-
-
Wu, J.1
Vallenius, T.2
Ovaska, K.3
Westermarck, J.4
Mäkelä, T.P.5
Hautaniemi, S.6
-
89
-
-
84918495009
-
Microtubules regulate focal adhesion dynamics through MAP4K4
-
Yue, J., M. Xie, X. Gou, P. Lee, M.D. Schneider, and X. Wu. 2014. Microtubules regulate focal adhesion dynamics through MAP4K4. Dev. Cell. 31:572-585. http://dx.doi.org/10.1016/j.devcel.2014.10.025
-
(2014)
Dev. Cell.
, vol.31
, pp. 572-585
-
-
Yue, J.1
Xie, M.2
Gou, X.3
Lee, P.4
Schneider, M.D.5
Wu, X.6
-
90
-
-
77951737987
-
The switchable integrin adhesome
-
Zaidel-Bar, R., and B. Geiger. 2010. The switchable integrin adhesome. J. Cell Sci. 123:1385-1388. http://dx.doi.org/10.1242/jcs.066183
-
(2010)
J. Cell Sci.
, vol.123
, pp. 1385-1388
-
-
Zaidel-Bar, R.1
Geiger, B.2
-
91
-
-
34547606042
-
Functional atlas of the integrin adhesome
-
Zaidel-Bar, R., S. Itzkovitz, A. Ma'ayan, R. Iyengar, and B. Geiger. 2007. Functional atlas of the integrin adhesome. Nat. Cell Biol. 9:858-867. http://dx.doi.org/10.1038/ncb0807-858
-
(2007)
Nat. Cell Biol.
, vol.9
, pp. 858-867
-
-
Zaidel-Bar, R.1
Itzkovitz, S.2
Ma'ayan, A.3
Iyengar, R.4
Geiger, B.5
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