Life span extension by targeting a link between metabolism and histone acetylation in Drosophila

EMBO Reports

Volumn 17, Issue 3, 2016, Pages 455-469

  Peleg, Shahaf ^a   Feller, Christian ^a,c   Forne, Ignasi ^a   Schiller, Evelyn ^b   Sévin, Daniel C ^c,d   Schauer, Tamas ^a   Regnard, Catherine ^a   Straub, Tobias ^a   Prestel, Matthias ^a,e   Klima, Caroline ^a   Schmitt Nogueira, Melanie ^a   Becker, Lore ^b   Klopstock, Thomas ^e,f,g   Sauer, Uwe ^c   Becker, Peter B ^a   Imhof, Axel ^a,g   Ladurner, Andreas G ^a,g  

^a UNIVERSITY OF MUNICH   (Germany)

^b INSTITUTE OF EPIDEMIOLOGY   (Germany)

^c ETH ZURICH   (Switzerland)

^d Life Science Zurich   (Switzerland)

^e LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^f GERMAN CENTER FOR NEURODEGENERATIVE DISEASES DZNE   (Germany)

^g Germany 3 Munich Cluster for Systems Neurology   (Germany)

Author keywords

acetylation; ageing; chromatin; metabolism

Indexed keywords

ACETYL COENZYME A; ADENOSINE TRIPHOSPHATE CITRATE SYNTHASE; HISTONE; HISTONE DEACETYLASE INHIBITOR; HISTONE H4; PROTEOME; TRANSCRIPTOME; ACYLTRANSFERASE; CHAMEAU PROTEIN, DROSOPHILA; DROSOPHILA PROTEIN;

AGING; ANIMAL CELL; ARTICLE; CELL METABOLISM; CHROMATIN; CONTROLLED STUDY; DROSOPHILA MELANOGASTER; DRUG SENSITIVITY; ENZYME ACTIVITY; ENZYME BLOOD LEVEL; GENE EXPRESSION; GENETIC TRANSCRIPTION; HISTONE ACETYLATION; LIFE EXTENSION; LONGEVITY; MALE; METABOLOME; MITOCHONDRIAL RESPIRATION; NONHUMAN; OXYGEN CONSUMPTION; PHYSICAL ACTIVITY; PRIORITY JOURNAL; PROTEIN FUNCTION; TEMPERATURE; ACETYLATION; ANIMAL; GENETICS; GROWTH, DEVELOPMENT AND AGING; METABOLISM; PROTEIN PROCESSING;

ACETYLATION; ACETYLTRANSFERASES; ANIMALS; ATP CITRATE (PRO-S)-LYASE; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; HISTONES; LONGEVITY; PROTEIN PROCESSING, POST-TRANSLATIONAL;

EID: 84959462088     PISSN: 1469221X     EISSN: 14693178     Source Type: Journal    
DOI: 10.15252/embr.201541132     Document Type: Article

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